专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2010071488A1 IMPLANTABLE MEDICAL DEVICE AND METHOD FOR MONITORING SYNCHRONICITY OF THE VENTRICLES OF A HEART 审中-公开
标题翻译：用于监测心脏通气道的同步性的可植入医疗装置和方法
公开(公告)号：WO2010071488A1
公开(公告)日：2010-06-24
申请号：PCT/SE2008/000720
申请日：2008-12-17
申请人： ST. JUDE MEDICAL AB , HOLMSTRÖM, Nils , LJUNGSTRÖM, Karin , BROOME, Michael , EMANUELSSON, Cecilia
发明人： HOLMSTRÖM, Nils , LJUNGSTRÖM, Karin , BROOME, Michael , EMANUELSSON, Cecilia
IPC分类号： A61N1/362 , A61N1/365 , A61B5/053 , A61B5/08 , A61B5/11 , A61N1/368 , A61N1/372
CPC分类号： A61N1/3627 , A61B5/053 , A61B5/0538 , A61B5/0816 , A61B5/11 , A61B5/7239 , A61B5/7289 , A61N1/36521 , A61N1/36578 , A61N1/3684 , A61N1/3686
摘要： The present invention generally relates to the field of implantable heart stimulation devices, such as pacemakers, and similar cardiac stimulation devices that also are capable of monitoring and detecting electrical activities and events within the heart. More specifically, the present invention relates to an implantable medical device and a method for monitoring ventricular synchronicity of a heart. In particular, the present invention comprises measuring impedance signals that reflects septal wall movements and detecting impedance amplitude peaks in the impedance signal. A synchronicity index indicating a degree of synchronicity is determined based on detected impedance peaks, wherein at least two impedance peaks detected within a predetermined time window including a cardiac cycle or a part of a cardiac cycle indicates an increased dyssynchronicity in the ventricular contractions. The system also selects an optimal electrode configuration based on a minimum synchronicity index obtained by testing several electrode configurations.
摘要翻译：本发明一般涉及可植入的心脏刺激装置领域，例如起搏器和类似的心脏刺激装置，其也能够监测和检测心脏内的电活动和事件。更具体地，本发明涉及可植入医疗装置和用于监测心脏的心室同步性的方法。特别地，本发明包括测量反射隔壁移动的阻抗信号和检测阻抗信号中的阻抗幅度峰值。基于检测到的阻抗峰值确定表示同步度的同步性指标，其中在包括心动周期或心动周期的一部分的预定时间窗口内检测到的至少两个阻抗峰值表示心室收缩中增加的不同步性。该系统还基于通过测试多个电极配置获得的最小同步性指数来选择最佳电极配置。

2. 发明申请

WO2008118041A1 AN IMPLANTABLE CARDIAC DEVICE AND METHOD FOR MONITORING THE STATUS OF A CARDIOVASCULAR DISEASE 审中-公开
标题翻译：用于监测心血管疾病状态的可植入心脏装置和方法
公开(公告)号：WO2008118041A1
公开(公告)日：2008-10-02
申请号：PCT/SE2007/000288
申请日：2007-03-23
申请人： ST. JUDE MEDICAL AB , HOLMSTRÖM, Nils , ÖHLANDER, Malin , NOREN, Kjell , BLOMQVIST, Andreas , LJUNGSTRÖM, Karin
发明人： HOLMSTRÖM, Nils , ÖHLANDER, Malin , NOREN, Kjell , BLOMQVIST, Andreas , LJUNGSTRÖM, Karin
IPC分类号： A61N1/365 , A61N1/37
CPC分类号： A61N1/36521 , A61B5/0215 , A61B5/02405 , A61B5/053 , A61B5/4035 , A61B5/4836 , A61B5/7257 , A61N1/36564 , A61N1/36578 , A61N1/36592 , A61N1/3702
摘要： An implantable cardiac device comprises a heart stimulator (10, 12) for electricly stimulating the heart of a patient, detecting means (2, 4) for measuring a physiologic parameter which is affected by the status of a cardiovascular disease associated with sympathetic activation, signal processing means (6) for determining at least one of a low frequency, LF, and a very low frequency, VLF, Mayer wave component in the measured parameter, and an analysor for analyzing the determined Mayer wave component in relation to a predetermined reference value to determine the status of the cardiovascular disease. The detecting means comprise measuring means (2) arranged to measure, as said physiologic parameter, a mechanical change in at least one of the four chambers of the heart. In a corresponding method for monitoring the status of a cardiovascular disease associated with sympathetic activation of a patient having an implantable electric heart stimulator (10, 12) a physiologic parameter affected by the cardiac disease is measured. At least one of a low frequency, LF, and a very low frequency, VLF, Mayer wave component in the parameter is determined, and the wave component is analysed in relation to a predetermined reference value to determine the status of the cardiovascular disease. A mechanical change in at least one of the four chambers of the heart is measured as the physiologic parameter.
摘要翻译：可植入心脏装置包括用于电刺激患者心脏的心脏刺激器（10,12），用于测量受到与交感神经激活相关的心血管疾病状态影响的生理参数的检测装置（2,4），信号用于确定所测量的参数中的低频，低频和极低频，伏尔伏特梅耶波分量中的至少一个的处理装置（6），以及用于相对于预定参考值分析所确定的梅尔波分量的分析器以确定心血管疾病的状况。检测装置包括测量装置（2），其被布置成根据所述生理参数测量心脏的四个腔室中的至少一个中的机械变化。在用于监测与具有可植入电心脏刺激器（10,12）的患者的交感神经激活相关的心血管疾病的状态的相应方法中，测量受心脏病影响的生理参数。确定参数中的低频，低频和极低频VLF，梅耶波分量中的至少一个，并且相对于预定参考值分析波分量以确定心血管疾病的状态。测量心脏四个腔室中的至少一个的机械变化作为生理参数。

3. 发明申请

WO2008118047A1 IMPLANTABLE MEDICAL DEVICE COMPRISING AN OXYGEN SENSOR 审中-公开
标题翻译：包含氧传感器的可植入医疗装置
公开(公告)号：WO2008118047A1
公开(公告)日：2008-10-02
申请号：PCT/SE2007/001044
申请日：2007-11-27
申请人： ST. JUDE MEDICAL AB , HEDBERG, Sven-Erik , BLOMQVIST, Andreas , JÄRVERUD, Karin , LJUNGSTRÖM, Karin , LINDKVIST, Leif , LÖNN, Urban , HOLMSTRÖM, Nils
发明人： HEDBERG, Sven-Erik , BLOMQVIST, Andreas , JÄRVERUD, Karin , LJUNGSTRÖM, Karin , LINDKVIST, Leif , LÖNN, Urban , HOLMSTRÖM, Nils
IPC分类号： A61N1/37 , A61B5/02 , A61B5/08 , A61N1/02
CPC分类号： A61N1/3702 , A61B5/14542 , A61B5/1459 , A61N1/056 , A61N1/36557
摘要： Implantable medical device comprising an oxygen sensor adapted to measure the level of oxygen in oxygenized blood, and to generate an oxygen measurement signal in dependence of the level of oxygen. The oxygen sensor is adapted to perform measurements inside the heart, of blood entering the left atrium of a patient's heart. The obtained oxygen measurement signal is compared to a predetermined threshold level and an indication signal is generated in dependence of the comparison, and that the indication signal is indicative of the lung functionality of the patient.
摘要翻译：可植入医疗装置，其包括适于测量氧合血液中的氧气水平的氧传感器，以及根据氧水平产生氧测量信号。氧传感器适于在心脏内进行血液进入患者心脏左心房的血液。将获得的氧测量信号与预定阈值电平进行比较，并且根据比较生成指示信号，并且指示信号指示患者的肺功能。

4. 发明申请

WO2005107582A1 DETECTION OF DIASTOLIC HEART FAILURE 审中-公开
标题翻译：检测白内障心脏失败
公开(公告)号：WO2005107582A1
公开(公告)日：2005-11-17
申请号：PCT/SE2004/000698
申请日：2004-05-06
申请人： ST. JUDE MEDICAL AB , TORPO, Maria , ÖHLANDER, Malin , BJÖRLING, Anders , LJUNGSTRÖM, Karin
发明人： TORPO, Maria , ÖHLANDER, Malin , BJÖRLING, Anders , LJUNGSTRÖM, Karin
IPC分类号： A61B5/02
CPC分类号： A61N1/3627 , A61B8/06 , A61B8/13
摘要： An implantable medical apparatus for detecting diastolic heart failure, DHF, comprises a DHF determining device for determining at least one DHF parameter for detecting a DHF state of the heart of a patient. The DHF determining device comprises a means for determining, as said DHF parameter, the time length (DT,IVRT) of a predetermined phase of diastole. A pacemaker comprises such an apparatus and control means for optimising pacing therapy and pacemaker settings depending on the determined time length. A corresponding method of detecting diastolic heart failure, DHF, comprises the step of determining at least one DHF parameter for detecting a DHF state of the heart of a patient. This step comprises determining, as said DHF parameter, the time length (DT,IVRT) of a predetermined phase of diastole.
摘要翻译：用于检测舒张性心力衰竭的可植入医疗装置DHF包括DHF确定装置，用于确定用于检测患者心脏的DHF状态的至少一个DHF参数。 DHF确定装置包括用于根据所述DHF参数确定舒张期的预定阶段的时间长度（DT，IVRT）的装置。起搏器包括用于根据确定的时间长度优化起搏治疗和起搏器设置的这种装置和控制装置。检测舒张性心力衰竭DHF的相应方法包括确定至少一个DHF参数以检测患者心脏的DHF状态的步骤。该步骤包括根据所述DHF参数确定舒张期的预定相位的时间长度（DT，IVRT）。

5. 发明申请

WO2008130291A1 IMPLANTABLE MEDICAL SYSTEM FOR DETECTING INCIPIENT EDEMA 审中-公开
标题翻译：用于检测机动车辆的可植入医疗系统
公开(公告)号：WO2008130291A1
公开(公告)日：2008-10-30
申请号：PCT/SE2007/000396
申请日：2007-04-24
申请人： ST. JUDE MEDICAL AB , HEDBERG, Sven-Erik , BLOMQVIST, Andreas , JÄRVERUD, Karin , LJUNGSTRÖM, Karin , LINDKVIST, Leif , LÖNN, Urban
发明人： HEDBERG, Sven-Erik , BLOMQVIST, Andreas , JÄRVERUD, Karin , LJUNGSTRÖM, Karin , LINDKVIST, Leif , LÖNN, Urban
IPC分类号： A61N1/05 , A61N1/365
CPC分类号： A61N1/05 , A61B5/0084 , A61B5/0086 , A61B5/08 , A61B5/1116 , A61B5/1118 , A61B5/4878 , A61B5/7207 , A61N1/025 , A61N1/056 , A61N1/362
摘要： The present invention generally relates implantable medical systems and, in particular, to systems, devices and methods for detecting incipient edema. The medical system comprises an implantable medical lead including an optical sensor comprising a light source and a light detector. The medical system further comprises an edema detection circuit being adapted to: activate the light source to emit light, wherein said light is directed into lung tissue of a patient; obtain a light intensity value corresponding to an intensity of light received by the light detector; and evaluate the light intensity value to detect a consistency with incipient edema.
摘要翻译：本发明通常涉及可植入医疗系统，特别是涉及用于检测初期水肿的系统，装置和方法。医疗系统包括可植入医疗引线，其包括包括光源和光检测器的光学传感器。医疗系统还包括水肿检测电路，其适于：激活光源以发光，其中所述光被引导到患者的肺组织中; 获得与由光检测器接收的光的强度对应的光强度值; 并评估光强值以检测与初期水肿的一致性。

6. 发明申请

WO2003051457A1 AN IMPLANTABLE HEART STIMULATING DEVICE, A SYSTEM INCLUDING SUCH A DEVICE AND A MANNER OF USING THE SYSTEM 审中-公开
标题翻译：可植入心脏刺激装置，包括这样一个装置的系统和使用该系统的手段
公开(公告)号：WO2003051457A1
公开(公告)日：2003-06-26
申请号：PCT/SE2002/001817
申请日：2002-10-04
申请人： ST. JUDE MEDICAL AB , NORÉN, Kjell , LJUNGSTRÖM, Karin , KALLING, Sven , MANDAL, Lars , BJÖRLING, Anders
发明人： NORÉN, Kjell , LJUNGSTRÖM, Karin , KALLING, Sven , MANDAL, Lars , BJÖRLING, Anders
IPC分类号： A61N1/368
CPC分类号： A61N1/3627 , A61N1/36521 , A61N1/3682 , A61N1/3684
摘要： The invention concerns an implantable heart stimulating device (10) comprising, inter alia, a control circuit (14) adapted to enable at least the following: a) delivering electrical stimulating pulses to the two ventricles (RV, LV) of a heart with a variable time interval (ΔT) between the pulses; b) sensing signals receivable from electrodes (31, 32; 41, 42; 51 , 52; 61, 62) positionable at two different positions in the heart, c) deriving an impedance value (Z) based on said sensed signals, d) determining a minimum value (Z min ) and a maximum value (Z max ) of said impedance value (Z) during a heart cycle, e) determining a relationship between said minimum (Z min ) and maximum (Z max )values, f) varying said time interval (ΔT) and monitoring said relationship over a plurality of heart cycles, g) setting said time interval (ΔT) such that said relationship fulfi1s a predetermined requirement. The invention also concerns a system including such a heart stimulating device (10) as well as a manner of using such a system.
摘要翻译：本发明涉及一种植入式心脏刺激装置（10），其特别地包括控制电路（14），该控制电路适于至少能够实现以下功能：a）将电刺激脉冲输送到心脏的两个心室（RV，LV）脉冲之间的可变时间间隔（DeltaT）; b）感测可定位在心脏中两个不同位置的电极（31,32; 41,42; 51,52; 61,62）的信号，c）基于所述感测信号导出阻抗值（Z），d）在心脏周期中确定所述阻抗值（Z）的最小值（Z> min <）和最大值（Z> max <），e）确定所述最小值（Z> min <）和最大值（Z > max <）值，f）改变所述时间间隔（DeltaT）并监视多个心脏周期的所述关系，g）设置所述时间间隔（DeltaT）使得所述关系满足预定要求。本发明还涉及包括这种心脏刺激装置（10）的系统以及使用这种系统的方式。

7. 发明申请

WO2008118042A1 IMPLANTABLE MEDICAL DEVICE 审中-公开
标题翻译：可植入医疗器械
公开(公告)号：WO2008118042A1
公开(公告)日：2008-10-02
申请号：PCT/SE2007/000289
申请日：2007-03-23
申请人： ST. JUDE MEDICAL AB , HEDBERG, Sven-Erik , BLOMQVIST, Andreas , JÄRVERUD, Karin , LJUNGSTRÖM, Karin , LÖNN, Urban
发明人： HEDBERG, Sven-Erik , BLOMQVIST, Andreas , JÄRVERUD, Karin , LJUNGSTRÖM, Karin , LÖNN, Urban
IPC分类号： A61N1/37 , A61B5/02 , A61B5/08 , A61N1/02
CPC分类号： A61N1/3702 , A61B5/14542 , A61B5/1459 , A61N1/056 , A61N1/36557
摘要： Implantable medical device comprising an optical oxygen sensor adapted to measure the level of oxygen in oxygenized blood, and to generate an oxygen measurement signal in dependence of the level of oxygen. The oxygen sensor is adapted to perform measurements inside the heart, of blood entering the left atrium of a patient's heart. The obtained oxygen measurement signal is compared to a predetermined threshold level and an indication signal is generated in dependence of the comparison, and that the indication signal is indicative of the lung functionality of the patient.
摘要翻译：可植入医疗装置，其包括适于测量氧合血液中氧气水平的光学氧传感器，并且根据氧气水平产生氧气测量信号。氧传感器适于在心脏内进行血液进入患者心脏左心房的血液。将获得的氧测量信号与预定阈值电平进行比较，并且根据比较生成指示信号，并且指示信号指示患者的肺功能。

8. 发明申请

WO2006130055A1 PIEZOELECTRIC FILM 审中-公开
标题翻译：压电薄膜
公开(公告)号：WO2006130055A1
公开(公告)日：2006-12-07
申请号：PCT/SE2005/000823
申请日：2005-05-31
申请人： ST. JUDE MEDICAL AB , ERIKSSON, Tom , NILSSON, Kenth , JOHANSSON, Anna-Karin , LJUNGSTRÖM, Karin , LASHGARI, Koroush , POHL, Annika , WESTIN, Gunnar
发明人： ERIKSSON, Tom , NILSSON, Kenth , JOHANSSON, Anna-Karin , LJUNGSTRÖM, Karin , LASHGARI, Koroush , POHL, Annika , WESTIN, Gunnar
IPC分类号： H01L41/187 , C04B35/495
CPC分类号： C04B35/495 , A61N1/056 , A61N1/0565 , A61N1/36542 , A61N1/36564 , C01G33/00 , C01G33/006 , C01P2002/72 , C01P2002/77 , C01P2002/82 , C01P2002/88 , C01P2004/03 , C04B35/624 , C04B35/62645 , C04B35/62675 , C04B2235/3201 , C04B2235/3251 , C04B2235/3255 , C04B2235/441 , C04B2235/6562 , C04B2235/768 , C04B2235/80 , C23C18/1216 , C23C18/1225 , C23C18/1254 , C23C18/1283 , H01L41/1873 , H01L41/318
摘要： The invention refers to a method for producing a biocompatible material of the formula Na x K y NbO 3 , 0≤x≤0.8, 0.2≤y≤1, x+y=1, comprising the steps of: (i) providing a Na-precursor and a K-precursor for Na x K y NbO 3 ; (ii) mixing the precursors in solution, whereby they first react to form a sol and thereafter a gel; and heat treating the gel to obtain an oxide of the material Na x K y NbO 3 , 0≤x≤0.8, 0.2≤y≤1, x+y=1. Hereby, a biocompatible material having several advantages, such as a highly controlled composition, is produced. Further, the invention refers to a method for producing a film comprising the material, as well as a material and a film produced by the method of the invention. Moreover, the invention refers to an implant comprising the biocompatible film of the invention.
摘要翻译：本发明涉及一种制备式Na生物相容性材料的方法，其中0 = x = 0.8,0.2 = y = 1，x + y = 1，包括以下步骤：（i）提供Na +前体和K-前体，用于Na + > 3 ; （ii）将前体在溶液中混合，由此它们首先反应形成溶胶，然后凝胶; 并且对所述凝胶进行热处理以获得所述材料的氧化物，所述氧化物为Na 2 O 3，NbO 3，0 = x = 0.8,0.2 = y = 1，x + y = 1。因此，生产具有几个优点的生物相容性材料，例如高度控制的组合物。此外，本发明涉及一种制造包含该材料的膜的方法，以及通过本发明的方法制备的材料和膜。此外，本发明涉及包含本发明的生物相容性膜的植入物。

9. 发明申请

WO2006049538A1 DEVICE FOR EVALUATING POSITIONS OF AN IMPLANTABLE MEDICAL DEVICE 审中-公开
标题翻译：用于评估可植入医疗装置的位置的装置
公开(公告)号：WO2006049538A1
公开(公告)日：2006-05-11
申请号：PCT/SE2004/001600
申请日：2004-11-02
申请人： ST. JUDE MEDICAL AB , LJUNGSTRÖM, Karin , BJÖRLING, Anders , STRANDBERG, Hans
发明人： LJUNGSTRÖM, Karin , BJÖRLING, Anders , STRANDBERG, Hans
IPC分类号： A61N1/05
CPC分类号： A61N1/372 , A61B5/029 , A61B5/0452 , A61N1/08
摘要： The present invention relates to a device for evaluating positions of a medical lead during an implantation procedure, wherein the medical lead comprises at least one electrode and at least one sensor. The sensor is arranged to provide signals related to heart pumping activity. Furthermore, the device comprises measuring means arranged to record sensor signals and signals characteristic of the heart activity at different lead positions; storing means arranged to store the sensor signals; and processing means connected to the measurement means and is arranged to determine a measure of the heart activity at each lead position based on the recorded signals. Thus, physiologic parameters reflecting hemodynamic performance are derived and evaluated for each lead position in order to determine the optimal site with respect to a desired heart muscle reaction.
摘要翻译：本发明涉及一种用于在植入过程期间评估医用引线的位置的装置，其中所述医用引线包括至少一个电极和至少一个传感器。传感器布置成提供与心脏泵送活动有关的信号。此外，该装置包括测量装置，其被设置为在不同的引导位置记录心脏活动特征的传感器信号和信号; 存储装置，被布置成存储传感器信号; 以及连接到所述测量装置的处理装置，并且被布置成基于所记录的信号来确定每个引导位置处的心脏活动度量。因此，针对每个引导位置导出和评估反映血液动力学性能的生理参数，以便确定相对于所需心脏肌肉反应的最佳位置。

10. 发明申请

WO2004008959A1 A CONGESTIVE HEART FAILURE MONITOR 审中-公开
标题翻译：一个焦虑心脏故障监测器
公开(公告)号：WO2004008959A1
公开(公告)日：2004-01-29
申请号：PCT/SE2003/001081
申请日：2003-06-23
申请人： ST JUDE MEDICAL AB , HOLMSTRÖM, Nils , OBEL, Martin , NORLIN, Anna , DAHLBERG, Kenneth , BJÖRLING, Anders , KALLING, Sven , LJUNGSTRÖM, Karin , NORÉN, Kjell
发明人： HOLMSTRÖM, Nils , OBEL, Martin , NORLIN, Anna , DAHLBERG, Kenneth , BJÖRLING, Anders , KALLING, Sven , LJUNGSTRÖM, Karin , NORÉN, Kjell
IPC分类号： A61B5/053
CPC分类号： A61B5/0538 , A61B5/053 , A61N1/3627
摘要： A congestive heartvfailure monitor comprises an impedance measuring unit to measure the impedance between at least two electrodes intended to be implanted in a patient such that a change in the left atrium volume results in a change of the measured impedance. Analysing means are provided for analysing the measured impedance for detecting an incipient congestive heart failure.
摘要翻译：充血性心脏衰竭监测器包括阻抗测量单元，用于测量旨在植入患者中的至少两个电极之间的阻抗，使得左心房容积的变化导致测量的阻抗的变化。提供分析装置用于分析用于检测初始充血性心力衰竭的测量阻抗。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式