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    • 2. 发明申请
    • STEM CELLS DERIVED FROM PRIMARY PLACENTA TISSUE AND CELLULAR THERAPEUTIC AGENT CONTAINING SAME
    • 来自主要组织的细胞干细胞和包含其的细胞治疗剂
    • WO2012008733A3
    • 2012-04-19
    • PCT/KR2011005103
    • 2011-07-12
    • MARIA BIOTECHLIM JIN HOLEE YOUNG JAEPARK SAEYOUNG
    • LIM JIN HOLEE YOUNG JAEPARK SAEYOUNG
    • C12N5/074A61K35/50A61P25/00C12N5/02
    • C12N5/0607A61K35/50C12N5/0605
    • The present invention relates to stem cells derived from primary placenta tissue at 14 weeks or less of gestation, to a method for separation of same, to a method for proliferation of same, and to a cellular therapeutic agent containing the stem cells. More particularly, the present invention relates to stem cells derived from primary placenta tissue at 14 weeks or less of gestation, to a method for separation of same, to a method for proliferation of same, and to a cellular therapeutic agent containing the stem cells, wherein the stem cells: (a) exhibit positive immunological properties with respect to CD9, CD13, CD29, CD44, CD90, CD105 and HLA-class I, and negative immunological properties against CD14, CD19, CD34, CD38, CD45, CD127 and HLA-DR; (b) express genes of Oct4, Nanog, Tbn, Klf4, Activin and Rex1; (c) have the ability of differentiation into cells derived from an ectoderm, mesoderm, or endoderm; and are maintained for 30 generations or more in an undifferentiated state. In spite of being adult stem cells, adult stem cells derived from placenta tissue according to the present invention have excellent cell proliferation and advantageous differentiation ability compared to existing stem cells derived from placenta tissue, and thus can be efficiently used as a cellular therapeutic agent. In particular, the stem cells have the ability to differentiate into nerve cells, bone-forming cells, or pancreatic beta cells that secrete insulin, and are also efficient at treating bone defect diseases, nerve diseases, diabetes, etc.
    • 本发明涉及在14周或更少妊娠期从原代胎盘组织衍生的干细胞,其分离方法,其增殖方法和含有干细胞的细胞治疗剂。 更具体地说,本发明涉及在14周或更少妊娠期从原代胎盘组织衍生的干细胞,其分离方法,其增殖方法和含有干细胞的细胞治疗剂, 其中所述干细胞:(a)相对于CD9,CD13,CD29,CD44,CD90,CD105和HLA-I类呈现阳性免疫学特性,对CD14,CD19,CD34,CD38,CD45,CD127和HLA具有阴性免疫学特性 -DR; (b)表达Oct4,Nanog,Tbn,Klf4,Activin和Rex1的基因; (c)具有分化成源自外胚层,中胚层或内胚层的细胞的能力; 在未分化状态下维持30代以上。 尽管是成体干细胞,但与源自胎盘组织的现有干细胞相比,根据本发明的源自胎盘组织的成体干细胞具有优异的细胞增殖和有利的分化能力,因此可以有效地用作细胞治疗剂。 特别是,干细胞具有分化成分泌胰岛素的神经细胞,成骨细胞或胰腺β细胞的能力,并且也有效治疗骨缺损疾病,神经疾病,糖尿病等。
    • 5. 发明申请
    • DEVICE FOR DRIVING CRANE BOOM ASSEMBLY
    • 驱动起重机臂组件的装置
    • WO2013005978A3
    • 2013-04-11
    • PCT/KR2012005292
    • 2012-07-04
    • DONGYANG MECHATRONICS CORPLEE YOUNG JAEJEONG IN GWON
    • LEE YOUNG JAEJEONG IN GWON
    • B66C23/687B66C23/68
    • B66C23/701
    • The present invention relates to a device for driving a crane boom assembly. Said device for driving a crane boom assembly has a main boom, a plurality of inserting and withdrawing booms combined inside said main boom to insert and withdraw, a cylinder device for allowing some of said inserting and withdrawing booms to insert and withdraw, wires for allowing the rest of said inserting and withdrawing booms to be operated, and pulleys on which said wires are wound, wherein the device for driving a crane boom assembly comprises: a first cylinder which has a first rod that is fixed to said main boom, and a first cylinder body into which said first rod is inserted to emerge therefrom and which is fixed to a inserting and withdrawing boom, in order to allow said first inserting and withdrawing boom to insert and withdraw from said main boom when said first inserting and withdrawing boom to an Nth inserting and withdrawing boom (N is a natural number which of 4 or more) are sequentially inserted into the inside of said main boom; a second cylinder which has a second rod that is fixed to a second inserting and withdrawing boom, and a second cylinder body into which said second rod is inserted to emerge therefrom and which is fixed to a third inserting and withdrawing boom, in order to operate simultaneously with said first cylinder body and to allow said third inserting and withdrawing boom to insert and withdraw from said second inserting and withdrawing boom; a first wire having one end that is coupled with said main boom, and the other end that is coupled with said second inserting and withdrawing boom; a first pulley which is installed on said first inserting and withdrawing boom, and guides said first wire by hanging said first wire; a second wire having one end that is coupled with said second inserting and withdrawing boom, and the other end that is coupled with said main boom; and a second pulley which is installed on said first inserting and withdrawing boom, and guides said first wire by hanging said first wire.
    • 本发明涉及一种用于驱动起重机吊杆组件的装置。 所述用于驱动起重机悬臂组件的装置具有主悬臂,在所述主悬臂内部结合以插入和退出的多个插入和抽出悬臂,允许一些所述插入和抽出悬臂插入和抽出的缸体装置,用于允许 其余的所述插入和抽出的吊杆被操作,以及所述导线缠绕在其上的滑轮,其中,用于驱动起重机吊杆组件的装置包括:第一气缸,其具有固定到所述主吊杆的第一杆以及 第一缸体,所述第一杆插入所述第一缸体以从其中伸出并固定到插入和退出悬臂上,以便当所述第一插入和退出悬臂到达所述第一插入和退出悬臂时,允许所述第一插入和退出悬臂插入和退出所述主悬臂; 第N插拔吊杆(N为4以上的自然数)依次插入所述主吊杆的内部, 第二缸体,其具有固定在第二插拔起重臂上的第二杆,以及第二缸体,所述第二杆插入该第二缸体以从其中伸出并固定在第三插拔臂上,以便操作 与所述第一缸体同时并允许所述第三插入和退出吊杆插入和退出所述第二插入和退出吊杆; 第一金属线,其一端与所述主臂连接,另一端与所述第二插入抽出臂连接; 第一滑轮,其安装在所述第一插拔起重臂上,并且通过悬挂所述第一导线来引导所述第一导线; 第二金属丝,其一端与所述第二插拔用吊杆连结,另一端与所述主吊杆连结; 以及安装在所述第一插拔起重臂上的第二滑轮,并且通过悬挂所述第一导线来引导所述第一导线。