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1. 发明申请

WO2010131132A1 CLINICAL DECISION SUPPORT SYSTEMS WITH EXTERNAL CONTEXT 审中-公开
标题翻译：具有外部背景的临床决策支持系统
公开(公告)号：WO2010131132A1
公开(公告)日：2010-11-18
申请号：PCT/IB2010/051543
申请日：2010-04-09
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , OPFER, Roland , CARLSEN, Ingwer, C. , DUTTA, Autri , TULIPANO, P., Karina , VLOEMANS, Victor , BOROCZKY, Lilla , RENISCH, Steffen
发明人： OPFER, Roland , CARLSEN, Ingwer, C. , DUTTA, Autri , TULIPANO, P., Karina , VLOEMANS, Victor , BOROCZKY, Lilla , RENISCH, Steffen
IPC分类号： G06F19/00
CPC分类号： G06F19/325 , G06F19/00 , G06Q50/24
摘要： A clinical decision support (CDS) system comprises a patient treatment histories database (10, 32) and a patient case navigation tool (10, 30) operative to select a patient treatment history from the patient treatment histories database and to display a flowchart representation (50) of at least a portion of the selected patient treatment history. Optionally, the navigation tool (10, 30) is further operative to selectively display a flowchart representation (64, 66) of a portion or all of a patient nonspecific treatment guideline not coinciding with the selected patient treatment history. Optionally, the CDS system further comprises a patient records query engine (10, 40) operative to receive a query and apply same against the patient treatment histories database to retrieve query results, the navigation tool (10, 30) being further operative to generate a query responsive to user input and to display query results retrieved for the query.
摘要翻译：临床决策支持（CDS）系统包括患者治疗历史数据库（10,32）和患者病例导航工具（10,30），其可操作以从患者治疗历史数据库中选择患者治疗历史并显示流程图表示（ 50）所选择的患者治疗历史的至少一部分。可选地，导航工具（10,30）还可操作以选择性地显示与所选择的患者治疗历史不一致的患者非特异性治疗指南的一部分或全部的流程图表示（64,66）。可选地，CDS系统还包括患者记录查询引擎（10,40），其可操作以接收查询并将其应用于患者治疗历史数据库以检索查询结果，所述导航工具（10,30）进一步操作以产生查询响应用户输入并显示为查询检索的查询结果。

2. 发明申请

WO2010086776A1 SYSTEM FOR PROVIDING LUNG VENTILATION INFORMATION 审中-公开
标题翻译：提供肺通气信息的系统
公开(公告)号：WO2010086776A1
公开(公告)日：2010-08-05
申请号：PCT/IB2010/050305
申请日：2010-01-25
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , KABUS, Sven , OPFER, Roland , CARLSEN, Ingwer, C. , RENISCH, Steffen , SABCZYNSKI, Joerg , BARSCHDORF, Hans , VON BERG, Jens , BLAFFERT, Thomas , KLINDER, Tobias , LORENZ, Cristian , SCHADEWALDT, Nicole
发明人： KABUS, Sven , OPFER, Roland , CARLSEN, Ingwer, C. , RENISCH, Steffen , BARSCHDORF, Hans , VON BERG, Jens , BLAFFERT, Thomas , KLINDER, Tobias , LORENZ, Cristian , SCHADEWALDT, Nicole
IPC分类号： A61B5/08 , A61B6/03 , G06T7/00
CPC分类号： A61B6/5235 , A61B5/08 , A61B6/541 , G06T7/33 , G06T2207/10081 , G06T2207/30061
摘要： A system for displaying lung ventilation information, the system comprising an input (12) and a processing unit (15). The input being provided for receiving multiple CT images (71) of a lung, each CT image (71) corresponding to one phase of at least two different phases in a respiratory cycle. The processing unit (15) being configured to compare CT images (71) corresponding to different phases in the respiratory cycle for determining a deformation vector field for each phase, to generate for each phase a ventilation image (72) based on the corresponding deformation vector field, to spatially align the ventilation images (72), and to generate for at least one common position (62) in each one of the aligned ventilation images (72), a function (81) of a time course of a ventilation value for said common position (62), each ventilation value in the function (81) being based on the deformation vector fields corresponding to the aligned ventilation images (73).
摘要翻译：一种用于显示肺通气信息的系统，所述系统包括输入（12）和处理单元（15）。所述输入被提供用于接收肺的多个CT图像（71），每个CT图像（71）对应于呼吸周期中的至少两个不同相的一个相。所述处理单元（15）被配置为比较对应于呼吸周期中的不同相位的CT图像（71），以确定每个相位的变形矢量场，以根据相应的变形矢量为每个阶段生成通气图像（72）在空间上对准通气图像（72），并且为每个对齐的通气图像（72）中的至少一个公共位置（62）产生功能（81），其中通风值的时间过程为所述公共位置（62）中，所述功能（81）中的每个换气值基于对应于对齐的通气图像（73）的变形矢量场。

3. 发明申请

WO2010109350A2 PET/CT BASED THERAPY MONITORING SYSTEM SUPPORTED BY A CLINICAL GUIDELINE NAVIGATOR 审中-公开
标题翻译：基于PET / CT的临床指南导航器支持的治疗监测系统
公开(公告)号：WO2010109350A2
公开(公告)日：2010-09-30
申请号：PCT/IB2010/050638
申请日：2010-02-11
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , OPFER, Roland , BOROCZKY, Lilla , CARLSEN, Ingwer-Curt , DUTTA, Pradyumna , RENISCH, Steffen , SABCZYNSKI, Joerg , TULIPANO, Paola, Karina
发明人： OPFER, Roland , BOROCZKY, Lilla , CARLSEN, Ingwer-Curt , DUTTA, Pradyumna , RENISCH, Steffen , SABCZYNSKI, Joerg , TULIPANO, Paola, Karina
IPC分类号： A61B6/03 , G01T1/29 , G06F19/00
CPC分类号： G16H10/60 , A61B6/037 , A61B6/508 , G06F19/00 , G06F19/321 , G06Q50/24
摘要： An oncology monitoring system comprises: an image analysis module (42, 44) configured to perform an oncological monitoring operation based on images of a subject, for example acquired by positron emission tomography (PET) and computed tomography (CT); and a clinical guideline support module (10). The clinical guideline support module is configured to: display a graphical flow diagram (GFD) of a clinical therapy protocol for treating the subject comprising graphical blocks (B0, B1, B2, B3, B4, B5, B21, B211, B22, B221, B222, B223, B23, B231, B232) representing therapeutic or monitoring operations of the clinical therapy protocol including at least one monitoring operation performed by the image analysis module; annotate a graphical block of the graphical flow diagram with subject-specific information pertaining to a therapeutic or monitoring operation represented by the graphical block; and display an annotation (POP) of a graphical block (B211) responsive to selection of the graphical block by a user.
摘要翻译：肿瘤学监测系统包括：图像分析模块（42,44），其被配置为基于例如由正电子发射断层摄影（PET）和计算机断层摄影术获取的对象的图像来执行肿瘤学监测操作（CT）; 和临床指南支持模块（10）。临床指南支持模块被配置为：显示用于治疗患者的临床治疗方案的图形流程图（GFD），其包括图形块（B0，B1，B2，B3，B4，B5，B21，B211，B22，B221， B222，B223，B23，B231，B232）表示临床治疗方案的治疗或监测操作，包括由图像分析模块执行的至少一个监测操作; 利用与由图形块表示的治疗或监视操作有关的特定于受试者的信息来注释图形流程图的图形块; 并且响应于用户对图形块的选择而显示图形块的注释（POP）（B211）。

4. 发明申请

WO2010018477A2 MODEL ENHANCED IMAGING 审中-公开
标题翻译：模型增强成像
公开(公告)号：WO2010018477A2
公开(公告)日：2010-02-18
申请号：PCT/IB2009/053192
申请日：2009-07-22
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , SABCZYNSKI, Joerg , RENISCH, Steffen , CARLSEN, Ingwer-Curt , KABUS, Sven , OPFER, Roland , KAUS, Michael , BZDUSEK, Karl, Antonin , WEESE, Juergen , PEKAR, Vladimir
发明人： SABCZYNSKI, Joerg , RENISCH, Steffen , CARLSEN, Ingwer-Curt , KABUS, Sven , OPFER, Roland , KAUS, Michael , BZDUSEK, Karl, Antonin , WEESE, Juergen , PEKAR, Vladimir
IPC分类号： G06F19/00
CPC分类号： G06F19/3481 , A61B2034/105 , A61B2090/374 , A61B2090/3762 , A61N5/103 , A61N7/02 , A61N2005/1041 , G06F19/00 , G06F19/321 , G06F19/324 , G16H10/60 , G16H50/20 , G16H50/50
摘要： A therapy treatment response simulator includes a modeler (202) that generates a model of a structure of an object or subject based on information about the object or subject and a predictor (204) that generates a prediction indicative of how the structure is likely to respond to treatment based on the model and a therapy treatment plan. In another aspect, a system includes performing a patient state determining in silico simulation for a patient using a candidate set of parameters corresponding to another patient and producing a first signal indicative of a predicted state of the patient, and generating a second signal indicative of whether the candidate set of parameters are suitable for the patient based on a known state of the patient.
摘要翻译：治疗治疗反应模拟器包括基于关于对象或对象的信息生成对象或对象的结构的模型的建模器（202），以及生成表示结构如何响应的预测的预测器（204）基于模型治疗和治疗方案。在另一方面，一种系统包括使用与另一患者相对应的参数的候选组来执行患者状态的计算机模拟，并产生指示患者的预测状态的第一信号，以及产生指示是否基于患者的已知状态，候选参数组适合于患者。

5. 发明申请

WO2011010231A1 ANATOMY MODELING FOR TUMOR REGION OF INTEREST DEFIINITION 审中-公开
标题翻译：肿瘤学习区域的解剖学建模
公开(公告)号：WO2011010231A1
公开(公告)日：2011-01-27
申请号：PCT/IB2010/052689
申请日：2010-06-15
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , RENISCH, Steffen , OPFER, Roland
发明人： RENISCH, Steffen , OPFER, Roland
IPC分类号： G06T7/00
CPC分类号： G06T7/0012 , A61B6/037 , G06T2200/24 , G06T2207/10072 , G06T2207/20221 , G06T2207/30096
摘要： A hot spot detection system for automatically segmenting and quantifying hot spots in functional images includes a segmentation unit (76) to segment an anatomical image representation (72) into regions corresponding to anatomical structures of a subject. A hot spot detection unit (90) detects regions of high uptake from a functional second image representation (74). The regions of high tracer uptake indicate high metabolic activity which maybe caused by potentially hazardous tumor lesions or other malignant processes. However, a number of normally functioning organs uptake high amounts of imaging tracer, particularly FDG. Therefore, a suppression unit (102) suppresses regions of high tracer uptake in the functional second image representation based on the results of a classification unit (101). The classification unit classifies the regions of high tracer uptake according to their position relative to the anatomical structures segmented from the anatomical first image representation. The remaining unsuppressed regions of high uptake are identified by an identification unit (106) as one of potential lesion and non-potential lesion.
摘要翻译：用于在功能图像中自动分割和量化热点的热点检测系统包括将解剖图像表示（72）分割成对应于对象的解剖结构的区域的分割单元（76）。热点检测单元（90）从功能性第二图像表示（74）检测高摄取区域。高示踪剂摄取的区域表明可能由潜在的危险的肿瘤病变或其他恶性过程引起的高代谢活性。然而，许多正常功能的器官摄取大量成像示踪剂，特别是FDG。因此，抑制单元（102）基于分类单元（101）的结果来抑制功能性第二图像表示中的高示踪剂摄取的区域。分类单元根据其相对于从解剖学第一图像表示分割的解剖结构的位置对高示踪剂摄取的区域进行分类。剩余的未摄取的未被抑制的区域由识别单元（106）鉴定为潜在病变和非潜在病变之一。

6. 发明申请

WO2006000953A1 DISPLAYING A TRACHEOBRONCHIAL TREE 审中-公开
标题翻译：显示一个TRACHEOBRONCHIAL树
公开(公告)号：WO2006000953A1
公开(公告)日：2006-01-05
申请号：PCT/IB2005/051968
申请日：2005-06-15
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , WIEMKER, Rafael , BLAFFERT, Thomas , BUELOW, Thomas , RENISCH, Steffen , LORENZ, Cristian , WISCHMANN, Hans-Aloys
发明人： WIEMKER, Rafael , BLAFFERT, Thomas , BUELOW, Thomas , RENISCH, Steffen , LORENZ, Cristian , WISCHMANN, Hans-Aloys
IPC分类号： G06T5/50
CPC分类号： G06T11/206 , G06T7/12 , G06T7/62 , G06T2207/10072 , G06T2207/30028 , G06T2207/30061
摘要： The invention relates to automatically segmenting and displaying the tracheobronchial tree (400) and displaying clinical values (404) related to the segmented tracheobronchial tree (400).
摘要翻译：本发明涉及自动分割和显示气管支气管（400）并显示与分段的气管支气管结石（400）相关的临床值（404）。

7. 发明申请

WO2012160511A1 APPARATUS AND METHOD FOR GENERATING AN ATTENUATION CORRECTION MAP 审中-公开
标题翻译：用于产生衰减校正图的装置和方法
公开(公告)号：WO2012160511A1
公开(公告)日：2012-11-29
申请号：PCT/IB2012/052561
申请日：2012-05-22
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , BLAFFERT, Thomas , RENISCH, Steffen , SCHWEIZER, Bernd , HU, Zhiqiang
发明人： BLAFFERT, Thomas , RENISCH, Steffen , SCHWEIZER, Bernd , HU, Zhiqiang
IPC分类号： G06T7/00 , G01R33/48
CPC分类号： G06T11/005 , G01R33/481 , G06T7/11 , G06T7/155 , G06T7/174 , G06T7/181 , G06T2207/10084 , G06T2207/10088 , G06T2207/10104 , G06T2207/20152 , G06T2207/20221 , G06T2207/30004 , G06T2207/30008 , G06T2207/30061
摘要： The invention relates to an apparatus for generating an attenuation correction map. An image providing unit (5, 6) provides an image of an object comprising different element classes and a segmentation unit (11) applies a segmentation to the image for generating a segmented image comprising image regions corresponding to the element classes. The segmentation is based on at least one of a watershed segmentation and a body contour segmentation based on a contiguous skin and fat layers in the image. A feature determination unit (12) determines features of at least one of a) the image regions and b) boundaries between the image regions depending on image values of the image and an assigning unit (13) assigns attenuation values to the image regions based on the determined features for generating the attenuation correction map. The performed image processing steps can allow for producing a high quality attenuation correction map, even if the initial image does not comprise image values related to the attenuation of radiation like a CT image.
摘要翻译：本发明涉及一种用于产生衰减校正图的装置。图像提供单元（5,6）提供包括不同元素类别的对象的图像，并且分割单元（11）对图像应用分割以生成包括对应于元素类别的图像区域的分割图像。分割基于基于图像中的连续皮肤和脂肪层的分水岭分割和身体轮廓分割中的至少一个。特征确定单元（12）确定a）图像区域和b）图像区域之间的边界中的至少一个的特征，取决于图像的图像值，并且分配单元（13）基于图像区域向图像区域分配衰减值确定的用于产生衰减校正图的特征。执行的图像处理步骤可以允许产生高质量的衰减校正图，即使初始图像不包括像CT图像的辐射衰减相关的图像值。

8. 发明申请

WO2010035183A2 PATIENT SPECIFIC ANATOMICAL SKETCHES FOR MEDICAL REPORTS 审中-公开
标题翻译：患者特殊解剖医学报告草图
公开(公告)号：WO2010035183A2
公开(公告)日：2010-04-01
申请号：PCT/IB2009/054070
申请日：2009-09-17
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , LORENZ, Cristian , DRIES, Sebastian, P., M. , RENISCH, Steffen , VON BERG, Jens
发明人： LORENZ, Cristian , DRIES, Sebastian, P., M. , RENISCH, Steffen , VON BERG, Jens
IPC分类号： G06T17/00
CPC分类号： G06F19/3487 , G06F19/00 , G06F19/321 , G06T7/0012 , G06T7/12 , G06T7/149 , G06T19/20 , G06T2207/10072 , G06T2207/10116 , G06T2207/30012 , G06T2219/2021 , G16H15/00
摘要： The invention relates to a system (100) for producing a representation of an object in image data, based on a template coupled to a model of the object, the system comprising a model unit for adapting the model to the object in the image data, and a template unit for adapting the template to the adapted model on the basis of the coupling between the template and the model. The template defines a representation of the object which is simpler to interpret than the model. The template may be arranged to emphasize useful features of the object. The template comprises substantially fewer degrees of freedom and thus can be efficiently adapted to the model. Because the template of the invention is coupled to the model, the position, orientation and/or shape of the template is determined by the model adapted to the object in the image data. Hence, the template is adapted to the image data. The adapted template is capable of representing the object and its individual characteristics, e.g., the shape of the object as well as the position and/or orientation of the object with respect to an external reference system defined, e.g., based on the image data.
摘要翻译：本发明涉及一种用于基于耦合到对象模型的模板来产生图像数据中的对象的表示的系统（100），该系统包括用于使模型适应图像数据中的对象的模型单元，以及模板单元，用于基于模板和模型之间的耦合来将模板适配到适配模型。模板定义了比模型更简单的对象的表示。模板可以被布置为强调对象的有用特征。该模板包括基本上更少的自由度，因此可以有效地适应于该模型。因为本发明的模板耦合到模型，所以模板的位置，取向和/或形状由适于图像数据中的对象的模型确定。因此，该模板适合图像数据。适应的模板能够表示对象及其各自的特征，例如对象的形状以及对象相对于例如基于图像数据定义的外部参考系统的位置和/或取向。

9. 发明申请

WO2009101560A2 APPARATUS FOR SEGMENTING AN OBJECT COMPRISING SUB-OBJECTS 审中-公开
标题翻译：用于分配包含子对象的对象的设备
公开(公告)号：WO2009101560A2
公开(公告)日：2009-08-20
申请号：PCT/IB2009/050495
申请日：2009-02-06
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , BLAFFERT, Thomas , BARSCHDORF, Hans , VON BERG, Jens , DRIES, Sebastian, P., M. , LORENZ, Cristian , WIEMKER, Rafael , KLINDER, Tobias , FRANZ, Astrid, R. , RENISCH, Steffen
发明人： BLAFFERT, Thomas , BARSCHDORF, Hans , VON BERG, Jens , DRIES, Sebastian, P., M. , LORENZ, Cristian , WIEMKER, Rafael , KLINDER, Tobias , FRANZ, Astrid, R. , RENISCH, Steffen
IPC分类号： G06T7/00 , A61B5/00
CPC分类号： G06T5/003 , G06T7/11 , G06T7/149 , G06T2207/10081 , G06T2207/20041 , G06T2207/20081 , G06T2207/20124 , G06T2207/20192 , G06T2207/30061
摘要： The present invention relates to an apparatus (1) for segmenting an object comprising sub-objects shown in an object image. The apparatus comprises a feature image generation unit (2) for generating a feature image showing features related to intermediate regions between the sub-objects and a segmentation unit (3) for segmenting the sub-objects by using the object image and the feature image. Preferentially, the feature image generation unit (2) is adapted for generating a feature image from the object image. In a further embodiment, the feature image generation unit (2) comprises a feature enhancing unit for enhancing features related to intermediate regions between the sub-objects in the object image.
摘要翻译：本发明涉及一种用于分割包含物体图像中所示的子对象的物体的装置（1）。该装置包括：特征图像生成单元，用于生成显示与子对象之间的中间区域相关的特征的特征图像和用于通过使用对象图像和特征图像来分割子对象的分割单元（3）。优选地，特征图像生成单元（2）适于从对象图像生成特征图像。在另一实施例中，特征图像生成单元（2）包括特征增强单元，用于增强与对象图像中的子对象之间的中间区域相关的特征。

10. 发明申请

WO2007054907A1 ADAPTIVE POINT-BASED ELASTIC IMAGE REGISTRATION 审中-公开
标题翻译：自适应点弹性图像注册
公开(公告)号：WO2007054907A1
公开(公告)日：2007-05-18
申请号：PCT/IB2006/054183
申请日：2006-11-09
申请人： PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , KONINKLIJKE PHILIPS ELECTRONICS N.V. , FRANZ, Astrid , CARLSEN, Ingwer-Curt , RENISCH, Steffen , WISCHMANN, Hans
发明人： FRANZ, Astrid , CARLSEN, Ingwer-Curt , RENISCH, Steffen , WISCHMANN, Hans
IPC分类号： G06T3/00
CPC分类号： G06T3/0081
摘要： A point-based elastic registration method for registering a first image and a second image. Initially, a single control point is randomly placed (S2) with the source image region and optimal parameter settings in respect thereof are determined (S3) for performing elastic deformation (S4) in respect of the first image so as to optimise a similarity measure. Additional control points are then added (S6) one-by-one, and the elastic deformation process repeated each time (S8) in respect of the new control point set, until a predetermined stopping criterion is met, e.g. the resultant improvement in the similarity measure no longer exceeds some predetermined threshold value. Thus, a high speed, high quality registration method is provided without having to specify the number of control points initially.
摘要翻译：一种用于登记第一图像和第二图像的基于点的弹性登记方法。首先，单个控制点与源图像区域随机放置（S2），并且确定相对于第一图像执行弹性变形（S4）的最佳参数设置（S3），以便优化相似性度量。然后逐个添加附加的控制点（S6），并且相对于新的控制点集合每次重复弹性变形过程（S8），直到达到预定的停止标准为止。所得到的相似性度量的改善不再超过某个预定阈值。因此，提供高速，高质量的登记方法，而不必首先指定控制点的数量。

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