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1. 发明申请

WO2010086776A1 SYSTEM FOR PROVIDING LUNG VENTILATION INFORMATION 审中-公开
标题翻译：提供肺通气信息的系统
公开(公告)号：WO2010086776A1
公开(公告)日：2010-08-05
申请号：PCT/IB2010/050305
申请日：2010-01-25
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , KABUS, Sven , OPFER, Roland , CARLSEN, Ingwer, C. , RENISCH, Steffen , SABCZYNSKI, Joerg , BARSCHDORF, Hans , VON BERG, Jens , BLAFFERT, Thomas , KLINDER, Tobias , LORENZ, Cristian , SCHADEWALDT, Nicole
发明人： KABUS, Sven , OPFER, Roland , CARLSEN, Ingwer, C. , RENISCH, Steffen , BARSCHDORF, Hans , VON BERG, Jens , BLAFFERT, Thomas , KLINDER, Tobias , LORENZ, Cristian , SCHADEWALDT, Nicole
IPC分类号： A61B5/08 , A61B6/03 , G06T7/00
CPC分类号： A61B6/5235 , A61B5/08 , A61B6/541 , G06T7/33 , G06T2207/10081 , G06T2207/30061
摘要： A system for displaying lung ventilation information, the system comprising an input (12) and a processing unit (15). The input being provided for receiving multiple CT images (71) of a lung, each CT image (71) corresponding to one phase of at least two different phases in a respiratory cycle. The processing unit (15) being configured to compare CT images (71) corresponding to different phases in the respiratory cycle for determining a deformation vector field for each phase, to generate for each phase a ventilation image (72) based on the corresponding deformation vector field, to spatially align the ventilation images (72), and to generate for at least one common position (62) in each one of the aligned ventilation images (72), a function (81) of a time course of a ventilation value for said common position (62), each ventilation value in the function (81) being based on the deformation vector fields corresponding to the aligned ventilation images (73).
摘要翻译：一种用于显示肺通气信息的系统，所述系统包括输入（12）和处理单元（15）。所述输入被提供用于接收肺的多个CT图像（71），每个CT图像（71）对应于呼吸周期中的至少两个不同相的一个相。所述处理单元（15）被配置为比较对应于呼吸周期中的不同相位的CT图像（71），以确定每个相位的变形矢量场，以根据相应的变形矢量为每个阶段生成通气图像（72）在空间上对准通气图像（72），并且为每个对齐的通气图像（72）中的至少一个公共位置（62）产生功能（81），其中通风值的时间过程为所述公共位置（62）中，所述功能（81）中的每个换气值基于对应于对齐的通气图像（73）的变形矢量场。

2. 发明申请

WO2009101560A2 APPARATUS FOR SEGMENTING AN OBJECT COMPRISING SUB-OBJECTS 审中-公开
标题翻译：用于分配包含子对象的对象的设备
公开(公告)号：WO2009101560A2
公开(公告)日：2009-08-20
申请号：PCT/IB2009/050495
申请日：2009-02-06
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , BLAFFERT, Thomas , BARSCHDORF, Hans , VON BERG, Jens , DRIES, Sebastian, P., M. , LORENZ, Cristian , WIEMKER, Rafael , KLINDER, Tobias , FRANZ, Astrid, R. , RENISCH, Steffen
发明人： BLAFFERT, Thomas , BARSCHDORF, Hans , VON BERG, Jens , DRIES, Sebastian, P., M. , LORENZ, Cristian , WIEMKER, Rafael , KLINDER, Tobias , FRANZ, Astrid, R. , RENISCH, Steffen
IPC分类号： G06T7/00 , A61B5/00
CPC分类号： G06T5/003 , G06T7/11 , G06T7/149 , G06T2207/10081 , G06T2207/20041 , G06T2207/20081 , G06T2207/20124 , G06T2207/20192 , G06T2207/30061
摘要： The present invention relates to an apparatus (1) for segmenting an object comprising sub-objects shown in an object image. The apparatus comprises a feature image generation unit (2) for generating a feature image showing features related to intermediate regions between the sub-objects and a segmentation unit (3) for segmenting the sub-objects by using the object image and the feature image. Preferentially, the feature image generation unit (2) is adapted for generating a feature image from the object image. In a further embodiment, the feature image generation unit (2) comprises a feature enhancing unit for enhancing features related to intermediate regions between the sub-objects in the object image.
摘要翻译：本发明涉及一种用于分割包含物体图像中所示的子对象的物体的装置（1）。该装置包括：特征图像生成单元，用于生成显示与子对象之间的中间区域相关的特征的特征图像和用于通过使用对象图像和特征图像来分割子对象的分割单元（3）。优选地，特征图像生成单元（2）适于从对象图像生成特征图像。在另一实施例中，特征图像生成单元（2）包括特征增强单元，用于增强与对象图像中的子对象之间的中间区域相关的特征。

3. 发明申请

WO2008065590A1 IMPROVED SEGMENTATION 审中-公开
标题翻译：改进分类
公开(公告)号：WO2008065590A1
公开(公告)日：2008-06-05
申请号：PCT/IB2007/054751
申请日：2007-11-22
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , LORENZ, Cristian , BARSCHDORF, Hans , VON BERG, Jens , BLAFFERT, Thomas , DRIES, Sebastian, P., M , KABUS, Sven
发明人： LORENZ, Cristian , BARSCHDORF, Hans , VON BERG, Jens , BLAFFERT, Thomas , DRIES, Sebastian, P., M , KABUS, Sven
IPC分类号： G06T5/00
CPC分类号： G06T7/149 , G06T7/11 , G06T2207/10072 , G06T2207/30048
摘要： A computer program product is described to adapt a shape model to a patient data set, the data set representing at least a region of anatomy of the patient, and in which the shape model is pre-adapted to a data set representing substantially the same anatomy of the same patient. This provides a surprisingly better segmentation of the data in the data set. In addition, A computer program product is described for the comparison of quantitative patient data and arranged to access quantitative patient data contained in a patient data record, characterized in that the quantitative patient data is in the form of an adapted shape model, adapted from a pre-adapted shape model. This extends the improvement derived by use of pre-adapted shape models and extends them to the use of pre-adapted shape models for data comparison.
摘要翻译：描述了计算机程序产品以将形状模型适应于患者数据集，所述数据集表示至少一个患者的解剖结构的区域，并且其中形状模型预先适应于表示基本上相同的解剖结构的数据集的同一病人。这为数据集中的数据提供了令人惊奇的更好的分割。另外，计算机程序产品被描述为用于比较定量患者数据并被安排用于访问包含在患者数据记录中的定量患者数据，其特征在于定量患者数据是适应形状模型的形式，预适应形状模型。这扩展了通过使用预先调整的形状模型得到的改进，并将其扩展到使用预先调整的形状模型进行数据比较。

4. 发明申请

WO2008065585A3 IMPROVED PATIENT DATA RECORD AND USER INTERFACE 审中-公开
公开(公告)号：WO2008065585A3
公开(公告)日：2008-06-05
申请号：PCT/IB2007/054740
申请日：2007-11-22
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , LORENZ, Cristian , BARSCHDORF, Hans , VON BERG, Jens , BLAFFERT, Thomas , DRIES, Sebastian, P., M. , KABUS, Sven
发明人： LORENZ, Cristian , BARSCHDORF, Hans , VON BERG, Jens , BLAFFERT, Thomas , DRIES, Sebastian, P., M. , KABUS, Sven
IPC分类号： G06F19/00
摘要： A patient data record is described comprising a mean model representative of the patient and further comprises at least one shape model to represent data concerning the patient, in which the said mean model comprises at least one region and the said shape model comprises at least one sub-section, and in which the at least one sub-section of the shape model is linked to the equivalent region of the mean model. This has the advantage of allowing greater structure to the patient record. Further a system is described to present patient data upon queries generated by a user and arranged to access the claimed patient data record, and which is further arranged to provide access to information in the sub-section of the shape model when a query generated by the user accesses the equivalent region of the mean model. This system allows full use of the improved patient data record.

5. 发明申请

WO2008026141A2 REDUCTION OF HEART MOTION ARTIFACTS IN THORACIC CT IMAGING 审中-公开
标题翻译：减少心脏CT成像中心脏运动的影响
公开(公告)号：WO2008026141A2
公开(公告)日：2008-03-06
申请号：PCT/IB2007/053403
申请日：2007-08-27
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , BARSCHDORF, Hans , VON BERG, Jens , KUHN, Michael, H. , LORENZ, Cristian , BLAFFERT, Thomas
发明人： BARSCHDORF, Hans , VON BERG, Jens , KUHN, Michael, H. , LORENZ, Cristian , BLAFFERT, Thomas
IPC分类号： G06T7/20 , A61B5/00
CPC分类号： G06T7/251 , G06T7/149 , G06T7/33 , G06T2200/04 , G06T2207/10081 , G06T2207/30048 , G06T2207/30061 , G06T2211/412
摘要： The invention relates to a system (100) for adapting a plurality of model meshes to a plurality of image data, the system comprising a registration unit (110) for registering the plurality of model meshes with the plurality of image data on the basis of a computation of a registration transformation for transforming the plurality of model meshes, and an adaptation unit (120) for adapting the plurality of registered model meshes to the plurality of image data on the basis of a computation of locations of mesh vertices of the plurality of model meshes. The system (100) may further comprise a computing unit (130) for computing sparse vector fields comprising vectors of displacements of vertices of the adapted model meshes, an approximation unit (140) for computing dense vector fields on the basis of the sparse vector fields, a merge unit (150) for merging image data sets by means of the computed dense vector fields, and a reconstruction unit (155) for reconstructing a motion-compensated image data from the computed dense vector fields. The described system (100) is capable of reducing motion artifacts in tomographic images computed from data acquired at a plurality of different cardiac cycle phases.
摘要翻译：本发明涉及一种用于将多个模型网格适配到多个图像数据的系统（100），该系统包括登记单元（110），用于基于多个图像数据向多个图像数据登记多个模型网格用于变换多个模型网格的注册变换的计算;以及适应单元，用于根据多个模型的网格顶点的位置的计算来将多个注册模型网格适配到多个图像数据网格。系统（100）还可以包括计算单元（130），用于计算包括适应模型网格的顶点位移矢量的稀疏矢量场，用于基于稀疏矢量场计算密集矢量场的近似单元（140），用于通过所计算的密集矢量场合并图像数据组的合并单元（150），以及用于从所计算的密集矢量场重构运动补偿图像数据的重建单元（155）。所描述的系统（100）能够减少从在多个不同的心动周期阶段获取的数据计算的断层图像中的运动伪影。

6. 发明申请

WO2006000953A1 DISPLAYING A TRACHEOBRONCHIAL TREE 审中-公开
标题翻译：显示一个TRACHEOBRONCHIAL树
公开(公告)号：WO2006000953A1
公开(公告)日：2006-01-05
申请号：PCT/IB2005/051968
申请日：2005-06-15
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , WIEMKER, Rafael , BLAFFERT, Thomas , BUELOW, Thomas , RENISCH, Steffen , LORENZ, Cristian , WISCHMANN, Hans-Aloys
发明人： WIEMKER, Rafael , BLAFFERT, Thomas , BUELOW, Thomas , RENISCH, Steffen , LORENZ, Cristian , WISCHMANN, Hans-Aloys
IPC分类号： G06T5/50
CPC分类号： G06T11/206 , G06T7/12 , G06T7/62 , G06T2207/10072 , G06T2207/30028 , G06T2207/30061
摘要： The invention relates to automatically segmenting and displaying the tracheobronchial tree (400) and displaying clinical values (404) related to the segmented tracheobronchial tree (400).
摘要翻译：本发明涉及自动分割和显示气管支气管（400）并显示与分段的气管支气管结石（400）相关的临床值（404）。

7. 发明申请

WO2006085250A2 IMAGING METHOD FOR COMPUTED TOMOGRAPHY AND COMPUTER TOMOGRAPH 审中-公开
标题翻译：计算机图像和计算机图像的成像方法
公开(公告)号：WO2006085250A2
公开(公告)日：2006-08-17
申请号：PCT/IB2006/050362
申请日：2006-02-03
申请人： PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , KONINKLIJKE PHILIPS ELECTRONICS N.V. , BUELOW, Thomas , WIEMKER, Rafael , LORENZ, Cristian , RENISCH, Steffen , BLAFFERT, Thomas
发明人： BUELOW, Thomas , WIEMKER, Rafael , LORENZ, Cristian , RENISCH, Steffen , BLAFFERT, Thomas
IPC分类号： G06T7/00 , A61B5/00
CPC分类号： G06T7/0012 , A61B6/032 , A61B6/481 , A61B6/5217 , G06T5/50 , G06T7/10 , G06T7/12 , G06T7/149 , G06T2207/10081 , G06T2207/10116 , G06T2207/30061 , G06T2207/30064 , G06T2207/30101
摘要： An imaging method for identifying abnormal tissue in the lung is provided, comprising the recording of slice images of the lung by means of X-ray radiation, recording of blood vessels, differentiation of blood vessels and abnormal tissue, segmentation of the abnormal tissue and display of the segmented abnormal tissue on an output device. In addition, a computer tomograph for identifying abnormal tissue in the lung is provided, having a radiation source for recording slice images of the lung and blood vessels by means of X-ray radiation, a computer unit for differentiating the blood vessels from the abnormal tissue and for segmenting the abnormal tissue, as well as an output device for displaying the segmented abnormal tissue. Furthermore, a computer program is provided for controlling a computer tomograph for an identification of abnormal tissue in the lung by means of a radiation source, designed to record slice images of the lung and blood vessels by means of X-ray radiation, to differentiate the blood vessels from abnormal tissue, to segment the abnormal tissue and to control an output device for displaying the abnormal tissue.
摘要翻译：提供了一种用于识别肺中异常组织的成像方法，包括通过X射线照射记录肺的切片图像，血管记录，血管和异常组织的分化，异常组织的分割和显示的输出装置上的分段异常组织。另外，提供了一种用于识别肺中的异常组织的计算机断层摄影机，具有用于通过X射线辐射记录肺和血管的切片图像的辐射源，用于将血管与异常组织分离的计算机单元并且用于分割异常组织，以及用于显示分割的异常组织的输出装置。此外，提供了一种计算机程序，用于通过辐射源来控制用于识别肺中的异常组织的计算机断层摄影机，其被设计成通过X射线辐射记录肺和血管的切片图像，以区分来自异常组织的血管，分割异常组织并控制用于显示异常组织的输出装置。

8. 发明申请

WO2006085254A1 METHOD OF AUTOMATIC EXTRACTION OF THE PULMONARY ARTERY TREE FROM 3D MEDICAL IMAGES 审中-公开
标题翻译：从三维医学图像中自动提取脉络膜的方法
公开(公告)号：WO2006085254A1
公开(公告)日：2006-08-17
申请号：PCT/IB2006/050375
申请日：2006-02-06
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , BUELOW, Thomas , WIEMKER, Rafael , BLAFFERT, Thomas , LORENZ, Cristian , RENISCH, Steffen
发明人： BUELOW, Thomas , WIEMKER, Rafael , BLAFFERT, Thomas , LORENZ, Cristian , RENISCH, Steffen
IPC分类号： G06T5/00
CPC分类号： G06T7/155 , G06T7/11 , G06T7/149 , G06T2200/04 , G06T2207/10081 , G06T2207/20044 , G06T2207/20156 , G06T2207/30061 , G06T2207/30101
摘要： An automated method (1) for the automatic extraction of a pulmonary vessel tree from a 3D medical image, such as multi-slice CT data, is disclosed. A segmented pulmonary vessel is identified as either an artery or a vein by determining a measure for arterialness for the vessel. The measure is based on a relation of the orientation of a local bronchus to the orientation of the segmented pulmonary vessel of the local bronchus. When a vessel is identified as a pulmonary artery, it is added to the pulmonary artery tree. Radii of the pulmonary artery and bronchus are measured automatically and positions where a ratio of these radii exhibits unusual values are presented in a display, preferably for suggesting further assessment by a radiologist, which for instance is useful for pulmonary embolism detection
摘要翻译：公开了一种用于从诸如多层CT数据的3D医学图像自动提取肺血管树的自动化方法（1）。通过确定血管动脉的测量，将分段的肺血管识别为动脉或静脉。该措施基于局部支气管的取向与局部支气管的分段肺血管的取向的关系。当血管被识别为肺动脉时，将其加入肺动脉树。自动测量肺动脉和支气管的半径，并将这些半径的比率显示出异常值的位置呈现在显示器中，优选用于表示放射科医师的进一步评估，其例如可用于肺栓塞检测

9. 发明申请

WO2012160511A1 APPARATUS AND METHOD FOR GENERATING AN ATTENUATION CORRECTION MAP 审中-公开
标题翻译：用于产生衰减校正图的装置和方法
公开(公告)号：WO2012160511A1
公开(公告)日：2012-11-29
申请号：PCT/IB2012/052561
申请日：2012-05-22
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , BLAFFERT, Thomas , RENISCH, Steffen , SCHWEIZER, Bernd , HU, Zhiqiang
发明人： BLAFFERT, Thomas , RENISCH, Steffen , SCHWEIZER, Bernd , HU, Zhiqiang
IPC分类号： G06T7/00 , G01R33/48
CPC分类号： G06T11/005 , G01R33/481 , G06T7/11 , G06T7/155 , G06T7/174 , G06T7/181 , G06T2207/10084 , G06T2207/10088 , G06T2207/10104 , G06T2207/20152 , G06T2207/20221 , G06T2207/30004 , G06T2207/30008 , G06T2207/30061
摘要： The invention relates to an apparatus for generating an attenuation correction map. An image providing unit (5, 6) provides an image of an object comprising different element classes and a segmentation unit (11) applies a segmentation to the image for generating a segmented image comprising image regions corresponding to the element classes. The segmentation is based on at least one of a watershed segmentation and a body contour segmentation based on a contiguous skin and fat layers in the image. A feature determination unit (12) determines features of at least one of a) the image regions and b) boundaries between the image regions depending on image values of the image and an assigning unit (13) assigns attenuation values to the image regions based on the determined features for generating the attenuation correction map. The performed image processing steps can allow for producing a high quality attenuation correction map, even if the initial image does not comprise image values related to the attenuation of radiation like a CT image.
摘要翻译：本发明涉及一种用于产生衰减校正图的装置。图像提供单元（5,6）提供包括不同元素类别的对象的图像，并且分割单元（11）对图像应用分割以生成包括对应于元素类别的图像区域的分割图像。分割基于基于图像中的连续皮肤和脂肪层的分水岭分割和身体轮廓分割中的至少一个。特征确定单元（12）确定a）图像区域和b）图像区域之间的边界中的至少一个的特征，取决于图像的图像值，并且分配单元（13）基于图像区域向图像区域分配衰减值确定的用于产生衰减校正图的特征。执行的图像处理步骤可以允许产生高质量的衰减校正图，即使初始图像不包括像CT图像的辐射衰减相关的图像值。

10. 发明申请

WO2008139344A1 MODEL-BASED SPECT HEART ORIENTATION ESTIMATION 审中-公开
标题翻译：基于模型的心跳心率估计
公开(公告)号：WO2008139344A1
公开(公告)日：2008-11-20
申请号：PCT/IB2008/051481
申请日：2008-04-17
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , BLAFFERT, Thomas , VON BERG, Jens , ZHAO, Zuo
发明人： BLAFFERT, Thomas , VON BERG, Jens , ZHAO, Zuo
IPC分类号： G06T7/00
CPC分类号： G06T7/75 , G06T2207/10104 , G06T2207/10108 , G06T2207/30048
摘要： When estimating a position or orientation of a patient's heart, a mesh model of a nominal heart is overlaid on a SPECT or PET image of the patient's heart and manipulated to conform to the image of the patient's heart. A mesh adaptation protocol applies opposing forces to the mesh model to constrain the mesh model from changing shape and to pull the mesh model to the shape of the patient's heart. A heart orientation estimator (60) iterates the mesh adaptation protocol a predetermined number of times, after which it defines a long axis of the left ventricle of the patient's heart as a line passing through the center of the mitral valve and the center of mass of the left ventricle. The long axis is then employed by a reorientation processor (70) to reorient the SPECT or PET image of the patient's heart, over which the mesh model was originally laid, to improve the accuracy of the PECT or PET image.
摘要翻译：当估计患者心脏的位置或取向时，标称心脏的网格模型覆盖在患者心脏的SPECT或PET图像上并被操纵以符合患者心脏的图像。网格适应协议将相反的力应用于网格模型，以将网格模型限制在不断变化的形状中，并将网格模型拉到患者心脏的形状。心脏取向估计器（60）将网格适应协议重复预定次数，然后将患者心脏的左心室的长轴定义为穿过二尖瓣中心的线，质心的中心左心室。然后由重新定向处理器（70）采用长轴以重新定向患者心脏的SPECT或PET图像，网格模型最初铺设在其上，以提高PECT或PET图像的准确度。

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