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1. 发明申请

WO2009044276A3 MOTION COMPENSATED IMAGE-GUIDED FOCUSED ULTRASOUND THERAPY SYSTEM 审中-公开
公开(公告)号：WO2009044276A3
公开(公告)日：2009-04-09
申请号：PCT/IB2008/003069
申请日：2008-10-01
申请人： INSIGHTEC LTD. , VORTMAN, JACOB , MEDAN, YOAV , ASSIF, Benny
发明人： VORTMAN, JACOB , MEDAN, YOAV , ASSIF, Benny
IPC分类号： A61N7/02 , G01R33/48
摘要： An image-guide therapy system comprises a thermal treatment device (e.g., an ultrasound transducer) configured for transmitting a therapeutic energy beam, and The system further comprises an imaging device (e.g., a magnetic resonant imaging (MRI) device) configured for acquiring images of the target tissue mass and the thermal treatment device. The system further comprises a controller configured for controlling thermal dose properties of the thermal treatment device to focus the energy beam on a target tissue mass located in an internal body region of a patient, and a processor configured for tracking respective positions of the thermal treatment device and the target tissue mass in a common coordinate system based on the acquired images. The system may optionally comprise a display configured for displaying the acquired images.

2. 发明申请

WO2009007847A3 TRANSRECTAL ULTRASOUND ABLATION PROBE 审中-公开
公开(公告)号：WO2009007847A3
公开(公告)日：2009-01-15
申请号：PCT/IB2008/002436
申请日：2008-07-08
申请人： INSIGHTEC LTD. , MEDAN, Yoav , ASSIF, Benny , GERSHTEIN, Vladimir
发明人： MEDAN, Yoav , ASSIF, Benny , GERSHTEIN, Vladimir
IPC分类号： A61N7/02
摘要： Transrectal ultrasound probes, systems and related methods. A probe includes an anisotropic balloon that defines a cavity for receiving a probe body that carries an ultrasound transducer. A vent tube is attached to or integral with, an outer surface of the anisotropic balloon. The balloon is structured to have inflation and elasticity characteristics that allow air bubbles between the balloon and rectal wall to be pushed away to form an improved acoustic interface while allowing bowel gas to be vented through the vent tube.

3. 发明申请

WO2013030671A1 AVOIDING MRI-INTERFERENCE WITH CO-EXISTING SYSTEMS 审中-公开
标题翻译：避免与同时存在的系统的MRI干扰
公开(公告)号：WO2013030671A1
公开(公告)日：2013-03-07
申请号：PCT/IB2012/002115
申请日：2012-08-30
申请人： INSIGHTEC, LTD. , VITEK, Shuki , ASSIF, Benny , GREENBERG, Adi
发明人： VITEK, Shuki , ASSIF, Benny , GREENBERG, Adi
IPC分类号： A61B5/055 , A61N7/02
CPC分类号： A61B5/055 , A61B8/0808 , A61B2017/22007 , A61B2090/374 , A61B2090/378 , A61N7/02 , A61N2007/0078
摘要： MRI interference with a co-existing treatment system may be reduced or avoided by carrying out RF-sensitive operations of the treatment system only when gradient field activity of the MRI system is suppressed.
摘要翻译：只有当MRI系统的梯度场活动被抑制时，才能通过执行治疗系统的RF敏感操作来减少或避免与共存治疗系统的MRI干扰。

4. 发明申请

WO2011021106A2 TECHNIQUES FOR TEMPERATURE MEASUREMENT AND CORRECTIONS IN LONG-TERM MAGNETIC RESONANCE THERMOMETRY 审中-公开
标题翻译：长时间磁共振热分析中的温度测量和校正技术
公开(公告)号：WO2011021106A2
公开(公告)日：2011-02-24
申请号：PCT/IB2010/002606
申请日：2010-08-19
申请人： INSIGHTEC LTD. , SCHMIDT, Rita , ZISO, Hadas , ASSIF, Benny , DOGATKIN, Osnat , FREUNDLICH, David , LEVY, Yoav , VITEK, Shuki
发明人： SCHMIDT, Rita , ZISO, Hadas , ASSIF, Benny , DOGATKIN, Osnat , FREUNDLICH, David , LEVY, Yoav , VITEK, Shuki
IPC分类号： G01R33/48
CPC分类号： A61B5/055 , A61N2007/0004 , G01R33/4804 , G01R33/56509 , G01R33/56563
摘要： Techniques for temperature measurement and correction in long-term MR thermometry utilize a known temperature distribution in an MR imaging area as a baseline for absolute temperature measurement. Phase shifts that arise from magnetic field drifts are detected in one or more portions of the MR imaging area, facilitating correction of temperature measurements in an area of interest.
摘要翻译：用于长期MR测温的温度测量和校正技术利用MR成像区域中已知的温度分布作为绝对温度测量的基线。在MR成像区域的一个或多个部分中检测出由磁场漂移产生的相移，有助于校正感兴趣区域中的温度测量。

5. 发明申请

WO2011058437A1 CORRECTING ARTIFACTS CAUSED BY MOTION OF A MEDICAL DEVICE AND/OR PATIENT MOTION IN MAGNETIC RESONANCE THERMOMETRY 审中-公开
标题翻译：矫正由医疗器械运动引起的病人和/或患者运动的磁共振热分析
公开(公告)号：WO2011058437A1
公开(公告)日：2011-05-19
申请号：PCT/IB2010/003038
申请日：2010-11-10
申请人： INSIGHTEC LTD. , LEVY, Yoav , HANANEL, Arik , FREUNDLICH, David , HALEVY, Gilad , ASSIF, Benny , ZISO, Hadas
发明人： LEVY, Yoav , HANANEL, Arik , FREUNDLICH, David , HALEVY, Gilad , ASSIF, Benny , ZISO, Hadas
IPC分类号： G01R33/48
CPC分类号： G01R33/4804 , A61B5/055 , G01R33/4814 , G01R33/56509 , G01R33/56536
摘要： Techniques for correcting measurement artifacts in MR thermometry predict or anticipate movements of objects (e.g. a thermal treatment device) and/or movements of the patient (e.g. respiratory motion) in or near an MR imaging region that may potentially affect a phase background and then acquire a library of reference phase images corresponding to different phase backgrounds that result from the predicted movements. For each phase image subsequently acquired, one reference phase image is selected from the library of reference phase images to serve as the baseline image for temperature measurement purposes. To avoid measurement artifacts that arise from phase wrapping, the phase shift associated with each phase image is calculated incrementally, that is, by accumulating phase increments from each pair of consecutively scanned phase images.
摘要翻译：用于校正MR测温中的测量伪影的技术可预测或预测物体（例如热处理装置）的运动和/或在MR成像区域内或附近的患者（例如呼吸运动）的运动，这可能潜在地影响相位背景然后获得对应于由预测的运动产生的不同相位背景的参考相位图像库。对于随后获取的每个相位图像，从参考相位图像库中选择一个参考相位图像，以作为温度测量目的的基线图像。为了避免相位缠绕产生的测量伪影，逐渐计算与每个相位图像相关的相移，即通过从每对连续扫描的相位图像中累加相位增量来计算。

6. 发明申请

WO2011028505A1 TECHNIQUES FOR CORRECTING TEMPERATURE MEASUREMENT IN MAGNETIC RESONANCE THERMOMETRY 审中-公开
标题翻译：用于校正磁共振热分析中温度测量的技术
公开(公告)号：WO2011028505A1
公开(公告)日：2011-03-10
申请号：PCT/US2010/046429
申请日：2010-08-24
申请人： INSIGHTEC LTD. , ASSIF, Benny , DUMOLIN, Charles, Lucian , MALLOZZI, Richard, Philip , DARROW, Robert, David
发明人： ASSIF, Benny , DUMOLIN, Charles, Lucian , MALLOZZI, Richard, Philip , DARROW, Robert, David
IPC分类号： G01R33/48 , G01R33/565 , G01R33/58 , A61B5/055
CPC分类号： G01R33/4804 , G01R33/24 , G01R33/243 , G01R33/4814 , G01R33/565 , G01R33/56509 , G01R33/56563 , G01R33/58
摘要： Techniques for correcting temperature measurement in MR thermometry are disclosed. In particular, phase shifts that arise from factors other than temperature changes are detected, e.g. changes in a local magnetic field, magnetic susceptibility changes in a patient's body due to breathing or movement, or magnetic field drifts. The phase shifts are determined by means of MR responses of one or more micro-coils located in or near the region of interest.
摘要翻译：公开了用于校正MR测温中的温度测量的技术。特别地，检测出由除温度变化以外的因素引起的相移。局部磁场的变化，由于呼吸或移动，或磁场漂移，患者身体的磁化率变化。通过位于感兴趣区域或附近的一个或多个微线圈的MR响应来确定相移。

7. 发明申请

WO2014118632A1 SIMULATION-BASED FOCUSED-ULTRASOUND TREATMENT PLANNING 审中-公开
标题翻译：基于模拟的聚焦超声波治疗计划
公开(公告)号：WO2014118632A1
公开(公告)日：2014-08-07
申请号：PCT/IB2014/000382
申请日：2014-01-29
申请人： INSIGHTEC, LTD. , LEVY, Yoav , ASSIF, Benny , HALEVY, Gilad , HERTZBERG, Yoni
发明人： LEVY, Yoav , ASSIF, Benny , HALEVY, Gilad , HERTZBERG, Yoni
IPC分类号： A61B19/00
CPC分类号： A61B19/50 , A61B34/10 , A61B2034/101 , A61B2034/104 , A61B2034/105 , A61B2090/374 , A61B2090/3762 , A61N7/02 , A61N2007/0086 , A61N2007/0095
摘要： A focused-ultrasound or other procedure for treating a target within a tissue region can be planned iteratively by creating a treatment plan specifying a treatment location pattern and stimuli applied thereto, simulating the treatment, computationally predicting an effect of the simulated treatment, comparing the predicted effect against one or more treatment constraints (such as efficacy and/or safety thresholds), and, if a constraint is violated, repeating the simulation for an adjusted treatment plan.
摘要翻译：可以通过创建指定治疗位置模式和施加到其上的刺激的治疗计划来迭代地计划用于治疗组织区域内的靶的聚焦超声或其它程序，模拟治疗，计算地预测模拟治疗的效果，比较预测对于一个或多个治疗约束（例如功效和/或安全阈值）的效果，并且如果违反约束，则重复经调整的治疗计划的模拟。

8. 发明申请

WO2008015520A1 SYSTEM FOR TRACKING MEDICAL DEVICE USING MAGNETIC RESONANCE DETECTION 审中-公开
标题翻译：使用磁共振检测跟踪医疗器械的系统
公开(公告)号：WO2008015520A1
公开(公告)日：2008-02-07
申请号：PCT/IB2007/002134
申请日：2007-07-27
申请人： INSIGHTEC, LTD , ASSIF, Benny
发明人： ASSIF, Benny
IPC分类号： A61B5/055 , A61B5/06 , G01R33/28 , A61B19/00
CPC分类号： A61B5/06 , A61B5/055 , A61B2090/3958 , G01R33/287 , G01R33/4814
摘要： A system for using magnetic resonance to track a medical device, including an MR tracking device comprising one or more radiofrequency (RF) tracking coils adapted to receive a magnetic resonance MR response signal from nuclei excited by an RF pulse, the tracking device being attached to a medical device, wherein a dephasing gradient is applied perpendicular to the readout gradient before the RF response signal is received, thereby dephasing and attenuating any interfering signal emanating from remote nuclei, while the MR response signal is substantially unaffected. The system can also detect errors in tracking location by checking the amplitude of the signal from each coil and the detected distance between each coil, and correcting for such errors by ignoring data from coils having low amplitude or location deviating from known location relative to the other coils.
摘要翻译：一种使用磁共振来跟踪医疗设备的系统，包括一个MR跟踪设备，该MR跟踪设备包括一个或多个射频（RF）跟踪线圈，适用于从由RF脉冲激发的核接收磁共振MR响应信号，跟踪设备被附加到医疗装置，其中在接收到RF响应信号之前垂直于读出梯度施加去相位梯度，从而相对于从远程核发出的任何干扰信号衰减和衰减，同时MR响应信号基本上不受影响。该系统还可以通过检查来自每个线圈的信号的幅度和每个线圈之间的检测距离来检测跟踪位置中的错误，并且通过忽略具有相对于另一个的已知位置偏离低振幅或位置的线圈的数据来校正这种误差线圈。

9. 发明申请

WO2003042775A2 AN ADVANCED SHOPPING SYSTEM AND METHOD 审中-公开
标题翻译：先进的购物系统和方法
公开(公告)号：WO2003042775A2
公开(公告)日：2003-05-22
申请号：PCT/IL2002/000897
申请日：2002-11-10
申请人： HOVAV, Asher , ASSIF, Benny
发明人： ASSIF, Benny
IPC分类号： G06F
CPC分类号： G06Q30/06
摘要： The present invention is an advanced shopping system and method used for integrating traditional and electronic commerce channels. Each system user is provided with a shopping cart-unit, which is a portable device such as a dual-interface smart card. The system includes a number of item-units, whereineach item-unit is associated with an item or service presented for sale in a selling-area. Each item-unit contains in its memory distinctive item-information details that specifies the associated item or service. The selling-area can be an area in a store or a page in an online store Web site. The system also includes a number of selling-units that can be an in-store kiosk, a PC at home/office or a portable device. A system-server that handles the entire operation and security aspects of the system is also included. The user selcts an item that he would like to purchase and collects the item-information details from a specific item-unit into a shopping item-list that resides in the memory of his shopping cart-unit. By using a portable viewer-unit, the user can view, browse and update his shopping item-list. To complete his purchasing, the user introduces the shopping cart-unit to the selling-unit enabling the transfer of his shopping item-list and his personal details from the shopping cart-unit to the selling-unit. The user can then utilize the selling-unit to view, browse and update his shopping item-list, as well as confirm his purchase and pay for it.
摘要翻译：本发明是用于整合传统和电子商务渠道的高级购物系统和方法。每个系统用户都设置有购物车单元，其是诸如双接口智能卡的便携式设备。该系统包括多个项目单位，其中，所述项目单元与在销售区域中出售的项目或服务相关联。每个项目单位在其内存中包含指定相关项目或服务的独特项目信息详细信息。销售区域可以是商店中的一个区域，也可以是在线商店网站的页面。该系统还包括一些销售单元，可以是店内报亭，家庭/办公室的PC或便携式设备。还包括处理系统的整个操作和安全方面的系统服务器。用户选择他想要购买的物品，并将物品信息细节从特定物品单元收集到位于其购物车单元的存储器中的购物物品列表中。通过使用便携式查看器单元，用户可以查看，浏览和更新他的购物项目列表。为了完成购买，用户将购物车单元引入销售单元，从而将他的购物单和他的个人信息从购物车单元转移到销售单元。然后，用户可以利用销售单元来查看，浏览和更新他的购物项目列表，以及确认他的购买和支付。

10. 发明申请

WO2003042775A3 AN ADVANCED SHOPPING SYSTEM AND METHOD 审中-公开
公开(公告)号：WO2003042775A3
公开(公告)日：2003-05-22
申请号：PCT/IL2002/000897
申请日：2002-11-10
申请人： HOVAV, Asher , ASSIF, Benny
发明人： HOVAV, Asher , ASSIF, Benny
IPC分类号： G06F19/00
摘要： The implementation of an advanced shopping system in three shopping environments in a store (A), at home or office (B) and shopping on the go (C). A shopper (11), which is a system user, is shopping in a store (A) that includes a selling-area (13). The shopper (11) holds in his hand a shopping cart-unit (12), which is based on a dual-interface smart card. Items are presented for sale in the selling-area (13), wherein an item-unit (14) is located close to each of the item presented for sale in the selling area (13) and wherein each item-unit (14) contains in its memory distinctive item-information details that specofies the associated item. The shopper (11) selects an item that would purchase and positions of shopping cart-unit (14) that is associated with the selected item.

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