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1. 发明申请

WO2015161927A1 STABFÖRMIGER KÖRPER UND MEDIZINISCHES INSTRUMENT 审中-公开
标题翻译： BAR状体和医疗器械
公开(公告)号：WO2015161927A1
公开(公告)日：2015-10-29
申请号：PCT/EP2015/000845
申请日：2015-04-23
申请人： MARVIS MEDICAL GMBH
发明人： DÜRING, Klaus , DLAIKAN-CAMPOS, Nasib , VAN DIJK, Maarten
IPC分类号： A61L31/18
CPC分类号： A61B90/39 , A61B5/055 , A61B2090/3954 , A61L31/022 , A61L31/026 , A61L31/10 , A61L31/14 , A61L31/18 , A61M25/0127 , A61M25/09 , A61M2025/09166 , G01R33/287
摘要： Ein erfindungsgemäßer stabförmiger Körper umfasst einen Zentralabschnitt und einen Peripherabschnitt, wobei der Zentralabschnitt im Zentrum des stabförmigen Körpers angeordnet ist und vom Peripherabschnitt umschlossen ist. Sowohl der Zentralabschnitt als auch der Peripherabschnitt erstrecken sich über im Wesentlichen die gesamte Länge des stabförmigen Körpers. Der Zentralabschnitt weist zumindest ein in ein nicht-ferromagnetisches Matrixmaterial eingebettetes, nicht-metallisches Faserbündel auf. Das Matrixmaterial ist mit Markerpartikeln dotiert. Der Peripherabschnitt weist zumindest ein in ein undotiertes, nicht-ferromagnetisches Matrixmaterial auf. Der Durchmesser des Zentralabschnitts ist kleiner oder gleich 0,2 mm, bevorzugt kleiner oder gleich 0,15 mm und noch mehr bevorzugt kleiner oder gleich 0,1 mm und insbesondere kleiner oder gleich 0,08 mm.
摘要翻译：根据本发明的棒状体包括一中心部分和周边部分，所述中心部分被设置在棒状体的中心，并且由周缘部包围。二者的中心部分和周边部分上延伸大致棒状体的整个长度。的中央部分具有至少一个嵌入在非铁磁基体材料，非金属纤维束。所述基质材料掺杂有标记颗粒。外围部分具有在未掺杂的，非铁磁性基体材料的至少一种。中央部分的直径比小于或等于0.2mm，优选小于或等于0.15毫米，甚至比更优选小于或等于0.1毫米，特别是小于或等于0.08毫米。

2. 发明申请

WO2015017394A1 ACTIVELY TRACKED MEDICAL DEVICES 审中-公开
标题翻译：活力跟踪医疗器械
公开(公告)号：WO2015017394A1
公开(公告)日：2015-02-05
申请号：PCT/US2014/048583
申请日：2014-07-29
申请人： IMRICOR MEDICAL SYSTEMS, INC.
发明人： WEDAN, Steven R. , LLOYD, Thomas W. , BRUTLAG, Bryan A. , STENZEL, Gregg S. , KIMMEL, Scott
IPC分类号： A61M29/00
CPC分类号： A61M29/00 , A61B5/055 , A61B5/062 , A61B5/065 , A61B5/066 , A61B17/34 , A61B2034/2051 , G01R33/286 , G01R33/287
摘要： An actively tracked medical device comprising: a dilator having an inner tubular main body having a distal end and a proximal end, said tubular main body including at least first and second receiving channels positioned in a spaced apart relationship on an outer surface of said tubular main body; a region at the distal end of said tubular main body for supporting one or more tracking coils; an atrumatic tip portion operably coupled and positioned distal to said main body; a lumen extending through said tubular main body, said tip support and said atraumatic tip portion; and an outer polymer body having first and second ends, said outer polymer body operably covering said inner tubular main body and said tracking coils, said first end terminating adjacent a proximal end of said atraumatic tip portion and said second end terminating adjacent said hub.
摘要翻译：一种主动跟踪的医疗装置，包括：扩张器，具有具有远端和近端的内管状主体，所述管状主体至少包括在所述管状主体的外表面上以间隔开的关系定位的第一和第二接收通道身体; 在所述管状主体的远端处用于支撑一个或多个跟踪线圈的区域; 可操作地联接并定位在所述主体的远侧的起始尖端部分; 延伸穿过所述管状主体，所述尖端支撑件和所述无创伤尖端部分的内腔; 以及具有第一和第二端的外部聚合物本体，所述外部聚合物主体可操作地覆盖所述内部管状主体和所述跟踪线圈，所述第一端部邻近所述无创伤尖端部分的近端终止，所述第二端部终止于所述毂部附近。

3. 发明申请

WO2014142772A2 ENHANCEMENT OF MAGNETIC RESONANCE IMAGE RESOLUTION BY USING BIO-COMPATIBLE, PASSIVE RESONATOR HARDWARE 审中-公开
标题翻译：利用生物兼容无源谐振器硬件增强磁共振成像分辨率
公开(公告)号：WO2014142772A2
公开(公告)日：2014-09-18
申请号：PCT/TR2014/000083
申请日：2014-03-14
申请人： DEMIR, Hilmi Volkan
发明人： DEMIR, Hilmi Volkan , UNAL, Emre , GOKYAR, Sayim
CPC分类号： G01R33/34053 , G01R33/286 , G01R33/287 , G01R33/34007 , G01R33/34084 , G01R33/3628
摘要： Embodiments of the present invention address the problems with previously known MRI enhancement resonators. The embodiments provide capacitances that are sufficiently large to result in resonance frequencies that are sufficiently low for medical MRI applications in devices that are sufficiently small for implantation into the body. Further, the capacitance and resonance frequency of the MRI enhancement resonator may be easily adjusted to particular desired values by selecting corresponding thin-film dielectrics, or thicknesses of such thin-film dielectrics. Moreover, the design and geometry of the embodiments provide MRI enhancement resonators with high Q-factors. The construction and material of such MRI enhancement resonators also yield flexible and biocompatible devices that are appropriate for applications involving implantation into the body.
摘要翻译：本发明的实施例解决了先前已知的MRI增强谐振器的问题。这些实施例提供足够大的电容以产生足够低的谐振频率，用于足够小以便植入体内的装置中的医疗MRI应用。此外，通过选择相应的薄膜电介质或这种薄膜电介质的厚度，可以容易地将MRI增强型谐振器的电容和谐振频率调节到特定的期望值。此外，实施例的设计和几何形状提供了具有高Q因子的MRI增强谐振器。这种MRI增强型谐振器的结构和材料也产生适用于涉及植入体内的应用的灵活和生物相容性装置。

4. 发明申请

WO2013090577A1 MR ACTIVE TRACKING SYSTEM 审中-公开
标题翻译：主动跟踪系统
公开(公告)号：WO2013090577A1
公开(公告)日：2013-06-20
申请号：PCT/US2012/069513
申请日：2012-12-13
申请人： IMRICOR MEDICAL SYSTEMS, INC.
发明人： WEDAN, Steven R. , LLOYD, Thomas W. , STENZEL, Gregg S.
IPC分类号： A61B5/055
CPC分类号： G01R33/36 , A61B5/055 , G01R33/287 , G01R33/288 , G01R33/3685 , G01R33/3692
摘要： An active tracking system that overcomes the heating problems of conventional transmission line and signal line conductors is provided. The active tracking system includes at least one active tracking coil; at least one integrated circuit proximate the active tracking coil; a tracking receiver; a first MR safe means configured for transmitting a received signal to the tracking receiver; and a second MR safe means configured for communicating one or more signals from the tracking receiver to the integrated circuit at coil. The integrated circuit may also include frequency estimations, analog to digital conversion at the tracking coil location to reduce the amount of processing required in the tracking receiver thereby decreasing the potential for signals passing from the tracking coil location to the tracking receiver to interfere with MR imaging signals.
摘要翻译：提供了克服传统传输线和信号线导体的加热问题的主动跟踪系统。主动跟踪系统包括至少一个主动跟踪线圈; 靠近有源跟踪线圈的至少一个集成电路; 跟踪接收器; 被配置为将接收到的信号发送到跟踪接收器的第一MR安全装置; 以及第二MR安全装置，被配置为将来自跟踪接收器的一个或多个信号传送到线圈处的集成电路。集成电路还可以包括在跟踪线圈位置处的模数转换的频率估计，以减少跟踪接收器中所需的处理量，从而减少从跟踪线圈位置到跟踪接收器的信号的干扰MR成像信号。

5. 发明申请

WO2010148083A2 MRI-GUIDED DEVICES AND MRI-GUIDED INTERVENTIONAL SYSTEMS THAT CAN TRACK AND GENERATE DYNAMIC VISUALIZATIONS OF THE DEVICES IN NEAR REAL TIME 审中-公开
标题翻译： MRI引导设备和MRI导引的传统系统可以在实时跟踪和生成设备的动态可视化
公开(公告)号：WO2010148083A2
公开(公告)日：2010-12-23
申请号：PCT/US2010/038816
申请日：2010-06-16
申请人： SURGIVISION, INC. , JENKINS, Kimble L. , PIFERI, Peter , VIJ, Kamal
发明人： JENKINS, Kimble L. , PIFERI, Peter , VIJ, Kamal
IPC分类号： A61B5/055 , A61B1/32
CPC分类号： A61B5/062 , A61B5/0044 , A61B5/042 , A61B5/0422 , A61B5/053 , A61B5/055 , A61B5/065 , A61B5/415 , A61B5/418 , A61B18/02 , A61B18/18 , A61B34/10 , A61B34/20 , A61B2090/365 , A61B2090/374 , A61B2090/3954 , A61M5/00 , A61M25/01 , A61M25/0127 , A61M29/00 , A61M2025/0089 , A61M2025/0166 , A61M2025/0681 , A61M2025/09175 , G01R33/286 , G01R33/287
摘要： An MRI-guided medical device includes an elongated sheath, an elongated dilator, and an elongated needle. The sheath has a distal end, an opposite proximal end, and a central lumen extending between the proximal and distal ends. The sheath comprises MRI-compatible material and includes a tracking member located adjacent to the sheath distal end that is visible in an MRI image. The dilator comprises MRI-compatible material and is movably disposed within the sheath lumen. A distal end of the dilator is configured to extend outwardly from the sheath distal end and dilator includes at least one tracking member that is visible in an MRI image. The needle is movably disposed within the dilator lumen and is movable between stored and operative positions relative to the dilator. An RF shield may be coaxially disposed within the elongated sheath so as to surround a portion of the sheath central lumen.
摘要翻译： MRI引导的医疗装置包括细长护套，细长扩张器和细长针头。鞘具有远端，相对的近端和在近端和远端之间延伸的中心腔。护套包括与MRI相容的材料，并且包括位于MRI图像中可见的护套远端附近的跟踪构件。扩张器包括与MRI相容的材料，并且可移动地设置在鞘腔内。扩张器的远端构造成从护套远端向外延伸，并且扩张器包括在MRI图像中可见的至少一个跟踪构件。针可移动地设置在扩张器腔内，并且可在相对于扩张器的存储和操作位置之间移动。 RF屏蔽件可以同轴地设置在细长护套内，以便围绕护套中心腔的一部分。

6. 发明申请

WO2010102119A1 COMBINED FIELD LOCATION AND MRI TRACKING 审中-公开
标题翻译：组合场地和MRI跟踪
公开(公告)号：WO2010102119A1
公开(公告)日：2010-09-10
申请号：PCT/US2010/026227
申请日：2010-03-04
申请人： IMRICOR MEDICAL SYSTEMS, INC. , WEDAN, Steven, R. , LLOYD, Thomas, W. , STENZEL, Gregg, S.
发明人： WEDAN, Steven, R. , LLOYD, Thomas, W. , STENZEL, Gregg, S.
IPC分类号： A61B5/05
CPC分类号： G01R33/285 , A61B5/055 , A61B5/062 , A61B34/20 , A61B34/35 , A61B90/36 , A61B2034/2051 , A61B2090/364 , A61B2090/374 , G01R33/287
摘要： A composite tracking system for a medical device comprises a field location tracking system including at least one field location sensor structured to be coupled to a medical device, a magnetic resonance tracking system including at least one tracking coil structured to be coupled to a medical device, and a composite tracking processor operably coupled to the field location tracking system and the magnetic resonance tracking system. The composite tracking processor is operable to receive and process field location parameters from the field location tracking system and positional coordinates from the magnetic resonance tracking system to register a field location coordinate system to a magnetic resonance coordinate system.
摘要翻译：用于医疗设备的复合跟踪系统包括现场定位跟踪系统，其包括被构造为耦合到医疗设备的至少一个场位置传感器，包括构造为耦合到医疗设备的至少一个跟踪线圈的磁共振跟踪系统，以及可操作地耦合到所述场位置跟踪系统和所述磁共振跟踪系统的复合跟踪处理器。复合跟踪处理器可操作以从现场定位跟踪系统接收和处理现场定位参数以及来自磁共振跟踪系统的位置坐标，以将场位置坐标系记录到磁共振坐标系。

7. 发明申请

WO2010092495A1 METHOD AND SYSTEM OF TRACKING AND MAPPING IN A MEDICAL PROCEDURE 审中-公开
标题翻译：在医疗过程中跟踪和映射的方法和系统
公开(公告)号：WO2010092495A1
公开(公告)日：2010-08-19
申请号：PCT/IB2010/050226
申请日：2010-01-18
申请人： KONINKLIJKE PHILIPS ELECTRONICS, N.V. , MANZKE, Robert , CHAN, Raymond
发明人： MANZKE, Robert , CHAN, Raymond
IPC分类号： A61B5/055 , A61B19/00 , G01R33/26
CPC分类号： G01R33/286 , A61B5/064 , A61B6/547 , A61B34/20 , A61B2034/2051 , A61B2034/2072 , A61B2090/3954 , A61B2090/3983 , G01R33/24 , G01R33/26 , G01R33/287
摘要： A tracking system for a target anatomy of a patient can include a medical device having a magnetic source (299) integrally connected thereto and positionable in the target anatomy, a plurality of Optical Atomic Magnetometer (OAM) sensors (210) for detecting a magnetic field from the magnetic source, and a processor (120) for determining a position of the medical device based on one or more parameters associated with the detected magnetic field. Other embodiments can include connecting a magnetic source with the medical device and having the OAM sensors positionable in proximity to the target anatomy.
摘要翻译：用于患者的目标解剖结构的跟踪系统可以包括具有与其整体连接并可定位在目标解剖结构中的磁源（299）的医疗装置，用于检测磁场的多个光学原子磁强计（OAM）传感器（210）以及用于基于与检测到的磁场相关联的一个或多个参数来确定医疗设备的位置的处理器（120）。其他实施例可以包括将磁源与医疗装置连接并且使OAM传感器可定位在目标解剖结构附近。

8. 发明申请

WO2010086762A1 RF SAFE TRANSFORMER- COUPLED TRANSMISSION LINE FOR MRI WITH REDUCED ARTIFACTS 审中-公开
标题翻译：射频安全变压器 - 耦合传输线用于具有减少的艺术家的MRI
公开(公告)号：WO2010086762A1
公开(公告)日：2010-08-05
申请号：PCT/IB2010/050245
申请日：2010-01-20
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , WEISS, Steffen
发明人： WEISS, Steffen
IPC分类号： G01R33/28
CPC分类号： G01R33/287 , G01R33/288 , G01R33/3685
摘要： The present invention relates to an electrically conductive transmission line (100) adapted for use in the magnet bore of a magnetic resonance system, the line comprising at least one inductive coupling element (106) for coupling at least two lead segments (104) of the line, wherein the coupling element (106) further comprises a paramagnetic and/or ferromagnetic material (400).
摘要翻译：本发明涉及一种适于在磁共振系统的磁体孔中使用的导电传输线（100），该线包括至少一个感应耦合元件（106），用于将至少两个引线段（104）线，其中所述耦合元件（106）还包括顺磁性和/或铁磁材料（400）。

9. 发明申请

WO2010073176A1 SYSTEM, METHOD AND APPARATUS FOR CARDIAC INTERVENTION WITH MR STROKE DETECTION AND TREATMENT 审中-公开
标题翻译：用于心肌梗塞检测和治疗的心脏干预的系统，方法和装置
公开(公告)号：WO2010073176A1
公开(公告)日：2010-07-01
申请号：PCT/IB2009/055693
申请日：2009-12-11
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , WEISS, Steffen
发明人： WEISS, Steffen
IPC分类号： A61B5/055 , G01R33/28 , G01R33/563
CPC分类号： G01R33/56341 , A61B5/02007 , A61B5/055 , A61B5/4076 , A61B6/501 , G01R33/287 , G01R33/56366
摘要： A system for the early detection and treatment of catheter-induced ischemic strokes includes a magnetic resonance system (20) and a processor (36). The magnetic resonance system includes a sequence controller for performing each of a plurality of imaging sequences and a sequence memory (32) which stores at least a magnetic resonance angiography (MRA) sequence, a diffusion-weighted imaging (DWI) sequence, and a perfusion-weighted imaging (PWI) sequence. The processor is programmed to control the magnetic resonance system to perform the steps of: performing the MRA sequence to generate a baseline MRA image; performing a catheter-tracking procedure to track a catheter; performing the DWI sequence after the catheter procedure to generate a diffusion-weighted image; performing the PWI sequence to generate a perfusion-weighted image; and combining the diffusion-weighted image and the perfusion-weighted image to generate a combined image for evaluating the ischemic stroke.
摘要翻译：用于早期检测和治疗导管引起的缺血性卒中的系统包括磁共振系统（20）和处理器（36）。磁共振系统包括用于执行多个成像序列中的每一个的序列控制器和至少存储磁共振血管造影（MRA）序列，扩散加权成像（DWI）序列和灌注的序列存储器（32）加权成像（PWI）序列。处理器被编程为控制磁共振系统以执行以下步骤：执行MRA序列以生成基线MRA图像; 执行导管跟踪程序来跟踪导管; 在导管过程之后执行DWI序列以产生扩散加权图像; 执行PWI序列以产生灌注加权图像; 并组合扩散加权图像和灌注加权图像以产生用于评估缺血性中风的组合图像。

10. 发明申请

WO2010028508A1 CATHETER FOR MAGNETIC RESONANCE GUIDED PROCEDURES 审中-公开
标题翻译：磁共振引导程序导管
公开(公告)号：WO2010028508A1
公开(公告)日：2010-03-18
申请号：PCT/CA2009/001282
申请日：2009-09-11
申请人： SUNNYBROOK HEALTH SCIENCES CENTRE , ANDERSON, Kevan , WRIGHT, Graham
发明人： ANDERSON, Kevan , WRIGHT, Graham
IPC分类号： A61M25/095 , A61B5/055 , A61B5/06 , A61M25/098 , A61L29/02 , A61L29/04 , A61L29/18
CPC分类号： A61M25/01 , A61M25/0127 , A61M2025/0166 , A61M2205/3515 , G01R33/287 , G01R33/288 , G01R33/34084
摘要： A catheter for magnetic resonance (MR) guided procedures comprising: a catheter body having a lumen for accommodating an intravascular device; a magnetic coupling component in the catheter body, the magnetic coupling component being designed to magnetically couple with a conductive length on the intravascular device, the magnetic coupling resulting in a signal; the catheter having a connection to deliver the signal to a processor.
摘要翻译：一种用于磁共振（MR）引导程序的导管，包括：导管体，其具有用于容纳血管内装置的内腔; 导管主体中的磁耦合部件，所述磁耦合部件设计成与血管内装置上的导电长度磁耦合，所述磁耦合产生信号; 导管具有将信号传送到处理器的连接。

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