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1. 发明申请

WO2007022181A1 A LIGHT SCATTERING AND IMAGING OPTICAL SYSTEM 审中-公开
标题翻译：光散射和成像光学系统
公开(公告)号：WO2007022181A1
公开(公告)日：2007-02-22
申请号：PCT/US2006/031830
申请日：2006-08-15
申请人： HONEYWELL INTERNATIONAL INC. , FRITZ, Bernard, S. , COX, James, A. , REUTIMAN, Peter
发明人： FRITZ, Bernard, S. , COX, James, A. , REUTIMAN, Peter
IPC分类号： G01N21/53 , G01N15/14
CPC分类号： G01N15/1463 , G01N15/1434 , G01N15/1484 , G01N21/4788 , G01N21/53 , G01N2015/1447 , G01N2015/1493 , G01N2021/4707 , G01N2021/4716 , G02B5/1819 , G02B27/4244
摘要： An optical element (38) for conveying scattered (32, 33) and image (31) light to several detectors (35, 36, 37) . The optical element (38) has the properties of a dif tractive beam splitter and imaging lens. The detected light is from an illuminated target (12) . The optical element (38) is for conveying scattered light (32, 33) from a target (12) via several zones to specific detectors (36, 37), respectively. The latter optical element (38) may include a multiple annular zone dif f ractive structure on a hybrid lens .
摘要翻译：一种用于将散射（32,33）和图像（31）光传送到多个检测器（35,36,37）的光学元件（38）。光学元件（38）具有差动分束器和成像透镜的特性。检测到的光来自照射的目标（12）。光学元件（38）用于将散射光（32,33）从靶（12）经由多个区域分别传送到特定检测器（36,37）。后者的光学元件（38）可以包括混合透镜上的多个环形区域的不同结构。

2. 发明申请

WO2007075922A2 PORTABLE SAMPLE ANALYZER CARTRIDGE 审中-公开
标题翻译：便携式样品分析仪筒
公开(公告)号：WO2007075922A2
公开(公告)日：2007-07-05
申请号：PCT/US2006/048851
申请日：2006-12-22
申请人： HONEYWELL INTERNATIONAL INC. , REUTIMAN, Peter, L. , PADMANABHAN, Aravind , COX, James, A. , BARDELL, Ron, L. , REZACHEK, Tom, M. , CABUZ, Cleopatra , FRITZ, Bernard, S.
发明人： REUTIMAN, Peter, L. , PADMANABHAN, Aravind , COX, James, A. , BARDELL, Ron, L. , REZACHEK, Tom, M. , CABUZ, Cleopatra , FRITZ, Bernard, S.
IPC分类号： G01N15/00 , G01N15/14 , G01N33/49 , G01N35/00 , G01N35/08
CPC分类号： G01N35/085 , G01N15/1056 , G01N15/12 , G01N15/1459 , G01N15/1484 , G01N35/00603 , G01N35/00663 , G01N2015/0069 , G01N2015/0073 , G01N2015/008 , G01N2015/0084 , G01N2015/1062 , G01N2015/1486 , G06F19/00
摘要： A system relating to sample analyzers, and more particular, to sample analyzers that are simple to operate and have a reduced risk of providing an erroneous result to a user. In some cases, the sample analyzer may be a portable sample analyzer that includes a disposable fluidic cartridge. The operators of the analyzers need not be trained.
摘要翻译：与样本分析仪有关的系统，更具体地说，涉及样本分析仪，该样本分析仪操作简单并且降低了向用户提供错误结果的风险。在一些情况下，样品分析仪可以是包括一次性流体盒的便携式样品分析仪。分析仪的操作人员不需要接受培训。

3. 发明申请

WO2007075919A3 PORTABLE SAMPLE ANALYZER SYSTEM 审中-公开
公开(公告)号：WO2007075919A3
公开(公告)日：2007-07-05
申请号：PCT/US2006/048846
申请日：2006-12-22
申请人： HONEYWELL INTERNATIONAL INC. , PADMANABHAN, Aravind , COX, James, A. , FRITZ, Bernard, S. , REZACHEK, Tom, M. , REUTIMAN, Peter, N. , BARDELL, Ron, L. , CABUZ, Cleopatra
发明人： PADMANABHAN, Aravind , COX, James, A. , FRITZ, Bernard, S. , REZACHEK, Tom, M. , REUTIMAN, Peter, N. , BARDELL, Ron, L. , CABUZ, Cleopatra
IPC分类号： G01N15/14 , G01N35/00 , B01L3/00
摘要： A system relating to sample analyzers, and more particular, to sample analyzers that are simple to operate and have a reduced risk of providing an erroneous result to a user. In some cases, the sample analyzer may be a portable sample analyzer that includes a disposable ftuidic cartridge. The operators of the analyzers need not be trained.

4. 发明申请

WO2007075920A2 ANALYZER SYSTEM 审中-公开
标题翻译：分析仪系统
公开(公告)号：WO2007075920A2
公开(公告)日：2007-07-05
申请号：PCT/US2006/048847
申请日：2006-12-22
申请人： HONEYWELL INTERNATIONAL INC. , PADMANABHAN, Aravind , COX, James, A. , FRITZ, Bernard, S. , REZACHEK, Tom, M. , REUTIMAN, Peter, L. , BARDELL, Ron, L. , CABUZ, Cleopatra
发明人： PADMANABHAN, Aravind , COX, James, A. , FRITZ, Bernard, S. , REZACHEK, Tom, M. , REUTIMAN, Peter, L. , BARDELL, Ron, L. , CABUZ, Cleopatra
CPC分类号： G01N35/00603 , B01L3/502715 , B01L3/502723 , B01L3/50273 , B01L3/502746 , B01L9/527 , B01L2200/027 , B01L2200/04 , B01L2200/0636 , B01L2200/0684 , B01L2200/143 , B01L2200/146 , B01L2300/021 , B01L2300/044 , B01L2300/0627 , B01L2300/0672 , B01L2300/0816 , B01L2300/0877 , B01L2300/14 , B01L2400/0406 , B01L2400/0481 , B01L2400/0487 , G01N15/1404 , G01N15/1459 , G01N15/1484 , G01N21/53 , G01N29/032 , G01N33/5094 , G01N35/00663 , G01N2015/0069 , G01N2015/0073 , G01N2015/008 , G01N2015/0084 , G01N2015/1452 , G01N2015/1486 , G01N2035/00148 , G01N2035/00158 , G01N2035/00247 , G01N2035/1034 , G01N2035/1053 , G01N2291/02433 , G01N2291/02836 , G01N2291/02872
摘要： A system relating to sample analyzers, and more particular, to sample analyzers that are simple to operate and have a reduced risk of providing an erroneous result to a user. In some cases, the sample analyzer may be a portable sample analyzer that includes a disposable fluidic cartridge. The operators of the analyzers need not be trained.
摘要翻译：与样品分析仪有关的系统，更具体地说，涉及操作简单且降低向使用者提供错误结果的风险的样品分析仪。在一些情况下，样品分析仪可以是便携式样品分析仪，其包括一次性流体盒。不需要对分析仪的操作员进行培训。

5. 发明申请

WO2007084232A1 DIFFERENTIAL WHITE BLOOD COUNT ON A DISPOSABLE CARD 审中-公开
标题翻译：不可比拟的白血病计数器
公开(公告)号：WO2007084232A1
公开(公告)日：2007-07-26
申请号：PCT/US2006/047792
申请日：2006-12-14
申请人： HONEYWELL INTERNATIONAL INC. , FRITZ, Bernard, S. , PADMANABHAN, Aravind , REUTIMAN, Peter
发明人： FRITZ, Bernard, S. , PADMANABHAN, Aravind , REUTIMAN, Peter
IPC分类号： G01N15/14 , G01N33/49
CPC分类号： B01L3/502715 , B01L3/502776 , B01L9/527 , B01L2200/027 , B01L2200/0636 , B01L2200/10 , B01L2200/143 , B01L2300/0672 , B01L2300/0816 , B01L2300/087 , B01L2400/0481 , B01L2400/0487 , B01L2400/0605 , G01N33/5002 , G01N2015/008 , G01N2015/1486
摘要： An apparatus and approach for performing multipart differentiation such as, for example, three, four and five part differentiation of white blood cells in a card or cartridge. The may be a combination of several kinds of lysing and/or staining/marking in a variety of sequential and parallel runs to achieve the differentiation of the cells. Various cell counts may also be performed.
摘要翻译：用于进行多部分微分的装置和方法，例如卡或盒中白细胞的三，四和五部分分化。可以是多种顺序和平行运行中的几种裂解和/或染色/标记的组合，以实现细胞的分化。也可以执行各种细胞计数。

6. 发明申请

WO2006029358A2 DUAL USE DETECTORS FOR FLOW CYTOMETRY 审中-公开
标题翻译：用于流式细胞术的双用途检测器
公开(公告)号：WO2006029358A2
公开(公告)日：2006-03-16
申请号：PCT/US2005/032243
申请日：2005-09-08
申请人： HONEYWELL INTERNATIONAL INC. , FRITZ, Bernard, S. , PADMANABHAN, Aravind , COX, James, A.
发明人： FRITZ, Bernard, S. , PADMANABHAN, Aravind , COX, James, A.
IPC分类号： G01N15/14
CPC分类号： G01B11/272 , G01N15/1434 , G01N15/147 , G01N15/1484 , G01N35/085 , G01N2015/0069 , G01N2015/0073 , G01N2015/008 , G01N2015/0088 , G01N2015/0238 , G01N2015/1075 , G01N2015/1413 , G01N2015/1452 , G01N2015/1497
摘要： An optical alignment system for aligning a light beam with a core flow in a flow stream. The flow stream may have a sheath fluid and a core flow, where the core flow has a current position within the flow stream. A light source may be used to produce a light beam, and an optical element may be used to direct the light beam at the core flow. In some illustrative embodiments, an actuator is provided for moving the optical element, light source and/or flow stream such that the light directed by the optical element is aligned with the current position of the core flow.
摘要翻译：光学对准系统，用于使光束与流动流中的芯流对准。流动流可具有鞘流和核心流，其中核心流在流动流内具有当前位置。可以使用光源来产生光束，并且可以使用光学元件来将光束引导至芯流。在一些说明性实施例中，提供致动器用于移动光学元件，光源和/或流动流，使得由光学元件引导的光线与芯流的当前位置对准。

7. 发明申请

WO2007075355A1 SPECTROMETER METHOD AND APPARATUS FOR NEAR INFRARED TO TERAHERTZ WAVELENGTHS 审中-公开
标题翻译：近红外光谱仪的方法和设备对于TERAHERTZ波长
公开(公告)号：WO2007075355A1
公开(公告)日：2007-07-05
申请号：PCT/US2006/047783
申请日：2006-12-14
申请人： HONEYWELL INTERNATIONAL INC. , FRITZ, Bernard, S. , WOOD, Roland, A. , NUSSEIBEH, Fouad , FRITZ, Bernard, S.
发明人： FRITZ, Bernard, S. , WOOD, Roland, A. , NUSSEIBEH, Fouad , FRITZ, Bernard, S.
IPC分类号： G01J3/453 , G01J3/28 , G01J3/42
CPC分类号： G01J3/4531 , G01J3/0202 , G01J3/2823 , G01J3/42 , G01J3/4532
摘要： In accordance with the principles of the invention, a lamellar grating interferometer breaks the radiation down into its wavelength components. The two sets of teeth of the grating are moved relative to each other. The spectral output of the interferometer is focused on an array of detectors and data is stored for a large number of positions of the grating teeth. The collected data is then Fourier transformed to recover the spectrum of the radiation.
摘要翻译：根据本发明的原理，层状光栅干涉仪将辐射分解成其波长分量。光栅的两组齿相对于彼此移动。干涉仪的光谱输出集中在一组检测器上，数据存储在光栅齿的大量位置。然后将收集的数据进行傅里叶变换以恢复辐射的光谱。

8. 发明申请

WO2008055157A2 CIRCULAR POLARIZATION ILLUMINATION BASED ANALYZER SYSTEM 审中-公开
标题翻译：基于圆极化照明的分析仪系统
公开(公告)号：WO2008055157A2
公开(公告)日：2008-05-08
申请号：PCT/US2007/083004
申请日：2007-10-30
申请人： HONEYWELL INTERNATIONAL INC. , FRITZ, Bernard, S.
发明人： FRITZ, Bernard, S.
IPC分类号： G01N15/14 , G01N21/23 , G01N21/47
CPC分类号： G01N15/1404 , G01N15/1459 , G01N21/21 , G01N2015/008 , G01N2015/1075 , G01N2015/1413 , G01N2015/1477 , G01N2015/1486 , G01N2015/1493 , G01N2021/4707 , G01N2021/4792
摘要： A particle discriminator using circularly polarized light projected through a channel having target particles. Light may be propagated through the channel, with some light scattered separated into forward angle scattered light, small angle scattered light and unscattered light. The forward angle scattered light may be linearly polarized and detected. The small angle scattered light may be linearly polarized in a direction orthogonal to the direction of the polarization of the forward angle scattered light, and at least both these kinds of light may be detected. Data from these detected kinds of light may be analyzed to discriminate particles from one another.
摘要翻译：利用投射穿过具有目标粒子的通道的圆偏振光的粒子鉴别器。光可以通过通道传播，一些散射光分成前向散射光，小角散射光和未散射光。前向散射光可以被线偏振并被检测。小角度散射光可以在与前向散射光的偏振方向正交的方向上线性偏振，并且可以检测至少这两种光。来自这些检测到的光的数据可以被分析以区分彼此的颗粒。

9. 发明申请

WO2006133185A1 MULTI-BAND LENS 审中-公开
标题翻译：多带镜头
公开(公告)号：WO2006133185A1
公开(公告)日：2006-12-14
申请号：PCT/US2006/021907
申请日：2006-06-06
申请人： HONEYWELL INTERNATIONAL INC. , WOOD, Roland, A. , FRITZ, Bernard, S.
发明人： WOOD, Roland, A. , FRITZ, Bernard, S.
IPC分类号： G02B13/14
CPC分类号： G02B13/146
摘要： An optical lens system that focuses both a first band of wavelengths and a second band of wavelengths onto a common focal plane. In some cases, the lens system includes a first region for focusing a first band of wavelengths onto a focal plane, and a second region for focusing a second band of wavelengths onto the same focal plane. Depending on the wavelengths and materials involved, the first region may or may not focus the second band of wavelengths onto the focal plane, and in some cases, may or may not even transmit the second band of wavelengths to the focal plane. Likewise, the second region may or may not focus the first band of wavelengths onto the focal plane, and in some cases, may or may not even transmit the first band of wavelengths onto the focal plane, but this is not required. In some embodiments, an additional lens may be provided between the lens system and the common focal plane to help focus the first band of wavelengths and the second band of wavelengths onto the common focal plane. The additional lens may be made from a material or material system that transmits and focuses both the first band of wavelengths and the second band of wavelengths.
摘要翻译：一种将第一波长波段和第二波长带聚焦在公共焦平面上的光学透镜系统。在一些情况下，透镜系统包括用于将第一波长带聚焦到焦平面上的第一区域和用于将第二波长带聚焦到同一焦平面上的第二区域。取决于所涉及的波长和材料，第一区域可以或可以不将第二波长带聚焦到焦平面上，并且在一些情况下，可能甚至不会将第二波长带透射到焦平面。类似地，第二区域可以或可以不将第一波长带聚焦到焦平面上，并且在一些情况下，可能甚至不会将第一波长带传播到焦平面上，但是这不是必需的。在一些实施例中，可以在透镜系统和公共焦平面之间提供附加透镜，以帮助将第一波长波段和第二波长带聚焦到公共焦平面上。附加透镜可以由材料或材料系统制成，该材料或材料系统透射和聚焦第一波长波段和第二波长波段。

10. 发明申请

WO2006055562A1 RAMAN DETECTION BASED FLOW CYTOMETER 审中-公开
标题翻译：基于拉曼检测的流量计
公开(公告)号：WO2006055562A1
公开(公告)日：2006-05-26
申请号：PCT/US2005/041363
申请日：2005-11-16
申请人： HONEYWELL INTERNATIONAL, INC. , FRITZ, Bernard, S.
发明人： FRITZ, Bernard, S. , CABUZ, Cleopatra , PADMANABHAN, Aravind
IPC分类号： G01N15/14 , G01N21/65
CPC分类号： G01N21/658 , G01N15/147
摘要： A method and apparatus for enabling chemical identification of individual particles, cells of molecules by obtaining a Raman spectrum of a particle, cell or molecule as it flows past a sensing point in a flow cytometer. The particles, which may be cells or molecules, are associated with a suitable noble metal colloid or colloidal aggregate. Cellular particles may be associated with gold or silver colloidal particles by ultra-sonic sonification while in a sample preparation reservoir containing the gold or silver colloidal suspension. The colloid associated particles are then hydrodynamically focused into a single file by a fluid control module. The surface-enhance Raman Spectrum of individual particles are obtained by illuminating the particle with a laser as the particle flows past a sensing point and gathering the light that is non-elastically scattered (Raman scattered) by the particle. The surface-enhanced Raman spectrum is then analyzed to identify the particle.
摘要翻译：一种方法和装置，用于通过在流式细胞计数器中流过感测点时获得粒子，细胞或分子的拉曼光谱，从而能够化学鉴定单个颗粒，分子细胞。可以是细胞或分子的颗粒与合适的贵金属胶体或胶体聚集体相关联。在含有金或银胶体悬浮液的样品制备储存器中，细胞颗粒可以通过超声波超声处理与金或银胶体颗粒结合。然后通过流体控制模块将胶体相关颗粒流体动力聚焦成单个文件。当颗粒流过感测点并通过颗粒收集非弹性散射（拉曼散射）的光时，通过用激光照射颗粒来获得单个颗粒的表面增强拉曼光谱。然后分析表面增强拉曼光谱以鉴定颗粒。

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