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1. 发明申请

WO2004043241A2 EMBOLIZATION DEVICE AND A METHOD OF USING THE SAME 审中-公开
标题翻译：嵌入装置及其使用方法
公开(公告)号：WO2004043241A2
公开(公告)日：2004-05-27
申请号：PCT/US2003/036373
申请日：2003-11-12
申请人： FOGARTY, Thomas, J. , DREWS, Michael, J. , MODESITT, D, Bruce , HOLMGREN, Neil , WILLIS, David, B.
发明人： FOGARTY, Thomas, J. , DREWS, Michael, J. , MODESITT, D, Bruce , HOLMGREN, Neil , WILLIS, David, B.
IPC分类号： A61B
CPC分类号： A61B17/12118 , A61B17/12022 , A61B17/1214 , A61B17/12163 , A61B90/39 , A61B2017/00004 , A61B2017/1205 , A61B2090/3966 , A61F2/07 , A61F2/88 , A61F2/90 , A61F2002/065 , A61F2002/077
摘要： Non-expandable space-occupying devices (24) for treating voids (10) within the body are disclosed. The devices (24) can have multiple non-expandable space-occupying elements connected to a flexible leader. The devices (24) can be deployed by a catheter (80) at a treatment site (4). Methods of making the devices (24) are also disclosed.
摘要翻译：公开了用于处理主体内的空隙（10）的不扩张空间占用装置（24）。设备（24）可以具有连接到柔性引导件的多个不可扩展空间占用元件。装置（24）可以在治疗部位（4）处由导管（80）展开。还公开了制造装置（24）的方法。

2. 发明申请

WO2004058106A2 BIOLOGICALLY IMPLANTABLE PROSTHESIS AND METHODS OF USING THE SAME 审中-公开
标题翻译：生物可植入假体及其使用方法
公开(公告)号：WO2004058106A2
公开(公告)日：2004-07-15
申请号：PCT/US2003/041222
申请日：2003-12-20
申请人： ARBOR SURGICAL TECHNOLOGIES, INC. , FOGARTY, Thomas, J. , DREWS, Michael, J. , HOLMGREN, Neil , MODESITT, D., Bruce
发明人： FOGARTY, Thomas, J. , DREWS, Michael, J. , HOLMGREN, Neil , MODESITT, D., Bruce
IPC分类号： A61F2/24
CPC分类号： A61F2/2409 , A61B17/0401 , A61B2017/00243 , A61B2017/0406 , A61B2017/0417 , A61B2017/0496 , A61B2017/0608 , A61F2/2412 , A61F2/2415 , A61F2/2445 , A61F2002/30545 , A61F2220/0016 , A61F2220/0041 , A61F2220/0066 , A61F2220/0075 , A61F2250/001 , Y10S623/91
摘要： A biologically implantable prosthesis is disclosed. The prosthesis can have a circumferentially expandable wall and elements that prevent the wall from collapsing once the wall is expanded. The prosthesis can also have an engagement element configured to self-engage a second prosthesis. Methods of making and using the prosthesis are also disclosed.
摘要翻译：公开了一种生物可植入假体。假体可以具有可周向扩张的壁和防止壁一旦扩张就会塌陷的元件。假体还可以具有被配置成自接合第二假体的接合元件。还公开了制造和使用假体的方法。

3. 发明申请

WO2004098388A2 TISSUE SEPARATION APPARATUS AND METHOD 审中-公开
标题翻译：组织分离装置和方法
公开(公告)号：WO2004098388A2
公开(公告)日：2004-11-18
申请号：PCT/US2004/013634
申请日：2004-04-30
申请人： FOGARTY, Thomas, J. , MODESITT, D., Bruce , HOLMGREN, Neil
发明人： FOGARTY, Thomas, J. , MODESITT, D., Bruce , HOLMGREN, Neil
IPC分类号： A61B
CPC分类号： A61B17/0218 , A61B17/00008 , A61B17/32056 , A61B2017/320741
摘要： A tissue separation apparatus (2) is disclosed. The apparatus can have a separating member (10) that has a contracted state and an expanded state. When the separating member (10) is placed between first and second tissue layers (222 and 224), the separating member (10) can part the first tissue layer (222) from the second tissue layer (224). The separating member (10) can be moved into the contracted state to sever the first tissue layer (222). Methods of making and using the apparatus (2) are also disclosed.
摘要翻译：公开了一种组织分离装置（2）。该装置可以具有收缩状态和膨胀状态的分离构件（10）。当分离构件（10）被放置在第一和第二组织层（222和224）之间时，分离构件（10）可以从第二组织层（224）部分第一组织层（222）。分离构件（10）可以移动到收缩状态以切断第一组织层（222）。还公开了制造和使用设备（2）的方法。

4. 发明申请

WO2005020842A2 PROSTHESIS FIXTURING DEVICE AND METHODS OF USING THE SAME 审中-公开
标题翻译： PROSTHESIS FIXTURING DEVICE及其使用方法
公开(公告)号：WO2005020842A2
公开(公告)日：2005-03-10
申请号：PCT/US2004/026922
申请日：2004-08-19
申请人： ARBOR SURGICAL TECHNOLOGIES, INC. , FOGARTY, Thomas, J. , DREWS, Michael, J. , LANE, Ernest , HOLMGREN, Neil , GUTIERREZ, Federico
发明人： FOGARTY, Thomas, J. , DREWS, Michael, J. , LANE, Ernest , HOLMGREN, Neil , GUTIERREZ, Federico
IPC分类号： A61F
CPC分类号： A61F2/2412 , A61B17/0401 , A61B2017/00243 , A61B2017/0406 , A61B2017/0417 , A61B2017/0496 , A61B2017/0608 , A61F2/2409 , A61F2/2415 , A61F2002/30545 , A61F2250/001 , Y10T29/49826
摘要： Devices for fixturing a prosthesis to a first mass and methods of making and using the same are disclosed. Complementary fixturing devices and methods of making and using the same are also disclosed. The devices can be used to attach a heart valve gasket body to a biological annulus.
摘要翻译：公开了将假体固定到第一质量块的装置及其制造和使用方法。还公开了互补固定装置及其制造和使用方法。该装置可用于将心脏瓣膜垫片主体附接到生物环。

5. 发明申请

WO2010083030A1 SYSTEMS AND METHODS FOR INCREASING THE VELOCITY OF FLUID WITHIN BODY CONDUITS 审中-公开
标题翻译：增加体内流体速度的系统和方法
公开(公告)号：WO2010083030A1
公开(公告)日：2010-07-22
申请号：PCT/US2010/000070
申请日：2010-01-13
申请人： TOMKEN MEDICAL , BAKER, Kenneth, D. , FOGARTY, Thomas, J. , SONG, Yongnam , CARD, Tiffany, H. , DOERKSEN, Kyle, J. , EISNER, Jake , NICHOLSON, Dana, Robert
发明人： BAKER, Kenneth, D. , FOGARTY, Thomas, J. , SONG, Yongnam , CARD, Tiffany, H. , DOERKSEN, Kyle, J. , EISNER, Jake , NICHOLSON, Dana, Robert
IPC分类号： A61H19/00
CPC分类号： A61H15/0078 , A61H2007/009 , A61H2015/0014 , A61H2201/0149 , A61H2201/1215 , A61H2201/1418 , A61H2201/1604 , A61H2201/1623 , A61H2201/1628 , A61H2201/1635 , A61H2201/164 , A61H2201/1654 , A61H2201/1671 , A61H2201/169 , A61H2201/5064 , A61H2205/06 , A61H2205/067 , A61H2205/106 , A61H2205/108 , A61H2209/00
摘要： Systems and methods move fluid within a body lumen in a body region, e.g., for the treatment of deep vein thrombosis or pulmonary embolism, by providing an array of rollers on a base mutually spaced apart and carried for rotation about parallel axes. Each roller has a roller contact surface that advances into and out of contact with tissue as a result of rotation of the respective roller about its respective parallel axis. The systems and methods support the body region in a holder in association with the array of rollers. The systems and methods drive the array of rollers to individually rotate each roller to cyclically advance the roller contact surfaces into and out of engagement with the tissue region in a synchronized fashion along the fluid flow path to increase fluid velocity in the fluid flow path.
摘要翻译：系统和方法通过在相互间隔开并围绕平行轴旋转的底座上提供一组滚子，将体内区域内的流体移动到体内区域，例如用于治疗深静脉血栓形成或肺栓塞。每个辊具有辊接触表面，其由于相应辊绕其相应的平行轴的旋转而进入和脱离与组织的接触。系统和方法支持与滚子阵列相关联的支架中的主体区域。系统和方法驱动滚子阵列以单独地旋转每个滚轮以沿着流体流动路径以同步的方式将滚子接触表面循环地推进到组织区域和与组织区域脱离接合，以增加流体流动路径中的流体速度。

6. 发明申请

WO2002067787A2 ANASTOMOSIS OCCLUSION DEVICE 审中-公开
标题翻译： ANASTOMOSIS闭塞装置
公开(公告)号：WO2002067787A2
公开(公告)日：2002-09-06
申请号：PCT/US2002/004903
申请日：2002-02-20
申请人： NOVARE SURGICAL SYSTEMS, INC. , BUELNA, Terrence , GOLD, Adam , FOGARTY, Thomas, J. , HOWELL, Thomas , ANDERSON, Russell, J.
发明人： BUELNA, Terrence , GOLD, Adam , FOGARTY, Thomas, J. , HOWELL, Thomas , ANDERSON, Russell, J.
IPC分类号： A61B17/11
CPC分类号： A61B17/122 , A61B17/00234 , A61B17/00491 , A61B17/0057 , A61B17/0469 , A61B17/11 , A61B17/12022 , A61B17/12036 , A61B17/12109 , A61B17/12131 , A61B17/12172 , A61B2017/00252 , A61B2017/00641 , A61B2017/1135 , A61F2/01
摘要： An anastomosis occlusion device having a low-profile shaft assembly configured for insertion into the lumen of a vessel. The device includes an expandable region at the shaft assembly distal end with a sealing membrane that spans the expandable region, and a corresponding clamping member moveable toward the expandable region. Once inserted into the vessel lumen the expandable region is deployed from a first low-profile position into a second expanded position at the target site of the anastomosis. Movement of the distal end of the clamping member, which remains located outside the vessel, against the expanded region creates a seal at the target site allowing a blood-free, graft site.
摘要翻译：具有构造成插入血管内腔的低轮廓轴组件的吻合术闭塞装置。该装置包括在轴组件远端处的可扩展区域，其具有跨越可扩展区域的密封膜以及可朝向可扩展区域移动的对应夹紧构件。一旦插入血管内腔中，可扩展区域就从吻合的目标位置处的第一低轮廓位置展开到第二展开位置。保持位于血管外的夹紧构件的远端抵靠扩张区域的运动在目标部位处产生密封，从而允许无血的移植位点。

7. 发明申请

WO2012051244A1 APPARATUS, SYSTEMS, AND METHODS FOR AUGMENTING THE FLOW OF FLUID WITHIN BODY VESSELS 审中-公开
标题翻译：用于补充体内流体流动的装置，系统和方法
公开(公告)号：WO2012051244A1
公开(公告)日：2012-04-19
申请号：PCT/US2011/055889
申请日：2011-10-12
申请人： VENOUS HEALTH SYSTEMS, INC. , OLSON, Jonathan, M. , MANGANO, Salvatore, G. , DONOHOE, Brendan, M. , JOHANSSON, Peter, K. , LOTTI, Richard, A. , FOGARTY, Thomas, J.
发明人： OLSON, Jonathan, M. , MANGANO, Salvatore, G. , DONOHOE, Brendan, M. , JOHANSSON, Peter, K. , LOTTI, Richard, A. , FOGARTY, Thomas, J.
IPC分类号： A61H7/00
CPC分类号： A61H9/0078 , A61H9/0092 , A61H2201/1238 , A61H2201/164 , A61H2201/165 , A61H2201/169 , A61H2201/5007 , A61H2201/501 , A61H2201/5015 , A61H2201/5043 , A61H2201/5071 , A61H2209/00
摘要： Apparatus, systems, and methods are sized and configured to effectively and efficiently augment the flow of fluid within body vessels, not only during conditions in which a patient is bedbound and immobile, but also in conditions when the individual is out of bed, and completely mobile and ambulatory.
摘要翻译：设备，系统和方法的大小和构造可以有效地和有效地增加体内血液中的流体流动，不仅在患者卧床和不动的条件下，而且在个体脱床的条件下，并且完全移动和流动。

8. 发明申请

WO2006074163A2 RETRIEVABLE ENDOLUMINAL FILTER 审中-公开
标题翻译：可检测的内镜过滤器
公开(公告)号：WO2006074163A2
公开(公告)日：2006-07-13
申请号：PCT/US2006/000087
申请日：2006-01-03
申请人： CRUX BIOMEDICAL, INC. , JOHNSON, Eric , FOGARTY, Thomas, J. , ARKO, Frank , ELKINS, Jeff , SEERY, Martin
发明人： JOHNSON, Eric , FOGARTY, Thomas, J. , ARKO, Frank , ELKINS, Jeff , SEERY, Martin
IPC分类号： B01D71/06
CPC分类号： A61B17/221 , A61F2/01 , A61F2002/011 , A61F2002/016 , A61F2002/018 , A61F2230/0008 , A61F2230/001 , A61F2230/0067 , A61F2230/0095 , A61F2250/0067 , A61M25/0021 , A61M25/007 , A61M2025/0037 , A61M2025/004
摘要： In one embodiment of the present invention there is provided a filter having a first structural member extending along and clockwise about an axis, a second structural member extending along and counter clockwise about the axis and a material capture structure extending between the first and the second structural members and across the axis. Ih yet another embodiment, there is provided a filter having a first spiral shaped support member having an end; a second support member positioned to cross the first spiral support member and form a loop between the end and the place where the second support member crosses the first spiral support member; and a material capture structure extending across and secured to the loop. In one embodiment of the present invention there is provided a coated endoluminal filter having a support structure; a filtering structure attached to the support structure; a coating over at least a portion of support structure. In another alternative embodiment, there is provided an endoluminal filter having a support structure; and a filtering structure attached to the support structure; wherein, the support structure is generally symmetrical about a plane that is orthogonal to the flow direction of the filter and contains a crossover point between two structural elements of the support structure. In another alternative embodiment, there is provided an endoluminal filter, having a support structure; and a filtering structure attached to the support structure; wherein, the support structure is generally symmetrical about a plane that is parallel to the flow direction of the filter and contains both ends of the support structure.
摘要翻译：在本发明的一个实施例中，提供了一种过滤器，其具有沿着轴线延伸并沿着轴线顺时针方向延伸的第一结构件，围绕轴线沿着逆时针延伸的第二结构件以及在第一和第二结构之间延伸的材料捕获结构成员和跨轴。在另一个实施例中，提供了一种具有第一螺旋状支撑构件的过滤器，其具有一端; 定位成穿过第一螺旋支撑构件并在端部与第二支撑构件穿过第一螺旋支撑构件的位置之间形成环的第二支撑构件; 以及延伸跨越并固定到环的材料捕获结构。在本发明的一个实施例中，提供了一种具有支撑结构的涂覆的腔内过滤器; 附接到所述支撑结构的过滤结构; 在支撑结构的至少一部分上的涂层。在另一替代实施例中，提供了一种具有支撑结构的腔内过滤器; 以及附接到所述支撑结构的过滤结构; 其中，所述支撑结构大体上关于与所述过滤器的流动方向正交的平面对称，并且在所述支撑结构的两个结构元件之间包含交叉点。在另一替代实施例中，提供了一种具有支撑结构的腔内过滤器; 以及附接到所述支撑结构的过滤结构; 其中，所述支撑结构大致对称关于平行于所述过滤器的流动方向并且包含所述支撑结构的两端的平面。

9. 发明申请

WO2013019947A3 ASSEMBLIES, SYSTEMS, AND METHODS FOR INFUSING THERAPEUTIC AGENTS INTO THE BODY 审中-公开
公开(公告)号：WO2013019947A3
公开(公告)日：2013-02-07
申请号：PCT/US2012/049322
申请日：2012-08-02
申请人： VENOUS THERAPY, INC. , COMEROTA, Anthony, J. , FOGARTY, Thomas, J. , OLSON, Jonathan, M. , LOTTI, Richard, A.
发明人： COMEROTA, Anthony, J. , FOGARTY, Thomas, J. , OLSON, Jonathan, M. , LOTTI, Richard, A.
IPC分类号： A61M25/00
摘要： An infusion catheter assembly has the ability to infinitely titrate the length of a porous fluid distribution section in situ. The infusion catheter assembly thereby provides a length of infusion that can be infinitely varied over a prescribed range, to control the effective infusion length and the rate of infusion. Using the infusion catheter assembly, a physician has the capability to treat only the length of the vessel desired, thereby preventing excessive drug/patient exposures. The porous fluid distribution section can include an array of spaced apart apertures that vary in size and/or density along the length of the porous fluid distribution section, such that the flow rate remains essentially constant for a given inlet pressure independent of the effective infusion length.

10. 发明申请

WO1994014497A1 ADJUSTABLE VALVE FOR SURGICAL APPLICATIONS 审中-公开
标题翻译：适用于外科应用的可调节阀
公开(公告)号：WO1994014497A1
公开(公告)日：1994-07-07
申请号：PCT/US1993012283
申请日：1993-12-16
申请人： FOGARTY, Thomas, J.
发明人： FOGARTY, Thomas, J. , MOLLENAUER, Kenneth, H. , HERMANN, George, D. , HOWELL, Thomas, A. , MONFORT, Michelle, Y.
IPC分类号： A61M39/06
CPC分类号： A61M39/0613 , A61M2039/062 , A61M2039/0673
摘要： An adjustable surgical valve has a sealing body (106) with an axial passage extending through it, a toroidal body (111) axially aligned with the sealing body, and a device (110, 120) that selectively changes the relative axial positions of the sealing body and the toroidal body. The sealing body and the toroidal body have mating surfaces which radially compress the axial passage of the sealing body when the relative axial positions of the sealing body and the toroidal body are changed. This causes the axial passage to seal with an instrument (c) inserted into it, or to seal with itself if no instrument is inserted. Alternatively, or additionally, the sealing body may include a braided sleeve (138) coaxial with the axial passage and extending from the sealing body, and a device that selectively changes the relative axial positions of the sealing body and the extended part of the braided sleeve to elongate the braided sleeve. This causes the braided sleeve to contract radially, which compresses the axial passage of the sealing body radially. The sealing body is made of an elastomeric foam or an encapsulated gel. In a method of making a surgical valve, a sealing body is attached inside one end of a braided sleeve, the other end of which is threaded through the bore of a toroidal body, and the braided sleeve, toroidal body, and sealing body are inserted into the bore of a substantially cylindrical valve body.
摘要翻译：可调外科手术阀具有密封体（106），其具有延伸穿过其的轴向通道，与密封体轴向对准的环形体（111）和选择性地改变密封件的相对轴向位置的装置（110,120）身体和环形体。当密封体和环形体的相对轴向位置改变时，密封体和环形体具有径向压缩密封体的轴向通道的配合表面。这导致轴向通道与插入其中的仪器（c）密封，或者如果没有插入仪器则与其自身密封。或者或另外，密封体可以包括与轴向通道同轴并且从密封体延伸的编织套筒（138），以及选择性地改变密封体和编织套筒的延伸部分的相对轴向位置的装置以伸长编织套筒。这使得编织套筒径向收缩，从而径向压缩密封体的轴向通道。密封体由弹性体泡沫或胶囊化的胶体制成。在制造外科手术阀的方法中，将密封体安装在编织套筒的一端，其另一端穿过环形体的孔，并且将编织套筒，环形体和密封体插入进入基本上圆柱形的阀体的孔中。

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