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1. 发明申请

WO2017156259A1 SYNTHETIC CHORD FOR CARDIAC VALVE REPAIR APPLICATIONS 审中-公开
标题翻译：合成和弦适用于心脏瓣膜修复应用
公开(公告)号：WO2017156259A1
公开(公告)日：2017-09-14
申请号：PCT/US2017/021556
申请日：2017-03-09
申请人： LC THERAPEUTICS, INC.
发明人： LONGORIA, James
IPC分类号： A61F2/24 , A61B17/04 , A61B17/06 , A61L27/50
CPC分类号： A61F2/2457 , A61B2017/00783 , A61B2017/0406 , A61B2017/0409 , A61B2017/0419 , A61B2017/0443 , A61B2017/0464 , A61B2017/048 , A61F2/2436 , A61F2/2466 , A61F2210/0014 , A61F2220/0016 , A61F2230/0091 , A61F2250/0064
摘要： Synthetic chord devices and methods for using the same for connecting tissues are provided. Aspects of the synthetic chord devices include a first flexible connector having first and second ends. Located at the first end is an attachment element that includes a tissue piercing member coupled to a securing member. The securing member includes an elongated shape memory coil that is present in a removable sheath configured to maintain elongation of the shape memory coil. A reinforcing element is located at the second end. The devices and methods of the invention find use in a variety of applications, such as cardiac valve, e.g., mitral valve, repair.
摘要翻译：提供了用于连接组织的合成弦装置和使用其的方法。人造腱索装置的方面包括具有第一和第二端的第一柔性连接器。位于第一端处的是附接元件，其包括联接至固定构件的组织穿刺构件。固定构件包括存在于可移除护套中的细长形状记忆线圈，所述可移除护套被构造成保持形状记忆线圈的伸长。加强元件位于第二端。本发明的装置和方法可用于各种应用，例如心脏瓣膜，例如二尖瓣，修复。

2. 发明申请

WO2017136396A1 TISSUE AUGMENTATION SCAFFOLDS FOR USE WITH SOFT TISSUE FIXATION REPAIR SYSTEMS AND METHODS 审中-公开
标题翻译：组织增生支架用于软组织固定修复系统和方法
公开(公告)号：WO2017136396A1
公开(公告)日：2017-08-10
申请号：PCT/US2017/015954
申请日：2017-02-01
申请人： MEDOS INTERNATIONAL SÀRL , SENGUN, Mehmet Ziya
发明人： SENGUN, Mehmet Ziya , WHITTAKER, Gregory R. , CLEVELAND, Benjamin , BERTI, Stefano , DIAB, Tamim , PARRISH, William R. , THEIS, Reagan A.
IPC分类号： A61B17/04
CPC分类号： A61B17/0401 , A61B17/0483 , A61B17/0485 , A61B17/06133 , A61B17/06166 , A61B17/3421 , A61B50/20 , A61B50/30 , A61B2017/00477 , A61B2017/00526 , A61B2017/0053 , A61B2017/0403 , A61B2017/0404 , A61B2017/0406 , A61B2017/0409 , A61B2017/0414 , A61B2017/0417 , A61B2017/0446 , A61B2017/0448 , A61B2017/0464 , A61B2017/0495 , A61B2017/0496 , A61B2017/06176 , A61F2/0095 , A61F2/0805 , A61F2/0811
摘要： Devices, systems, and methods to improve both the reliability of soft tissue repair procedures and the speed at which the procedures are completed are provided. The devices and systems include one or more tissue augmentation constructs, which include constructs that are configured to increase a footprint across which suture applied force to tissue when the suture is tied down onto the tissue. The tissue augmentation constructs can be quickly and easily associated with the repair suture, and can be useful in many different tissue repair procedures that are disclosed in the application. In one exemplary embodiment, one or more constructs are disposed on a suture threader, which can be used to associate the construct(s) with a repair suture(s) being used to repair the soft tissue. Tissue augmentation constructs can include various blocks and patches, among other formations. Exemplary methods for manufacturing the tissue augmentation constructs are also provided.
摘要翻译：提供了用于改善软组织修复程序的可靠性和程序完成的速度的装置，系统和方法。所述装置和系统包括一个或多个组织增强构造，其包括被构造成增加足迹的构造，当缝线被系到组织上时，缝合线将力施加到组织上。组织增强构造可以快速且容易地与修复缝合相关联，并且可以用于本申请中公开的许多不同的组织修复过程。在一个示例性实施例中，一个或多个构造物设置在缝线穿线器上，其可用于使构建物与用于修复软组织的修复缝合线相关联。组织增强构建体可以包括各种块和贴片以及其他构造。还提供了用于制造组织增强构造的示例性方法。

3. 发明申请

WO2017087848A1 KNOTLESS ANCHOR DEVICES AND SYSTEMS AND USES THEREOF 审中-公开
标题翻译：无缝锚固装置和系统及其用途
公开(公告)号：WO2017087848A1
公开(公告)日：2017-05-26
申请号：PCT/US2016/062855
申请日：2016-11-18
申请人： THE UAB RESEARCH FOUNDATION, INC. , SOUTHERN RESEARCH INSTITUTE
发明人： KHOURY, Joseph , HERGENROTHER, Robert, W. , SCHEXNAILDER, Patrick, J.
IPC分类号： A61B17/04
CPC分类号： A61B17/0401 , A61B17/7037 , A61B17/7053 , A61B17/842 , A61B2017/0406
摘要： Described herein are knotless anchor devices, knotless tulip heads, and systems thereof. Also described herein are methods of using the knotless fixation devices knotless tulip heads, and systems thereof.
摘要翻译：这里描述的是无结锚定装置，无结郁金香头部及其系统。本文还描述了使用无结的郁金香头的无结固定装置及其系统的方法。

4. 发明申请

WO2016187406A1 MINIMALLY INVASIVE SURGICAL SUTURING DEVICE FOR PAPILLARY MUSCLES AND METHODS THEREOF 审中-公开
标题翻译：用于毛细血管的微型外科手术装置及其方法
公开(公告)号：WO2016187406A1
公开(公告)日：2016-11-24
申请号：PCT/US2016/033234
申请日：2016-05-19
申请人： LSI SOLUTIONS, INC.
发明人： SAUER, Jude, S.
IPC分类号： A61B17/00 , A61B17/04 , A61B17/06
CPC分类号： A61B17/0482 , A61B17/0469 , A61B2017/0406 , A61B2017/0472
摘要： A surgical suturing device is disclosed. The surgical suturing device has a forked guide tip having a plurality of legs, wherein each of the plurality of legs comprises a proximal end,an anatomical variation, and a distal end. A method of chord replacement for a heart valve is also disclosed. A suture is placed in a papillary muscle using a surgical suturing device having a forked guide tip and a papillary suture. A leaflet suture is placed in a leaflet. The papillary suture and the leaflet suture are loaded in a suture fastener from opposite directions in a coaxial fashion. The length of the papillary suture and/or the leaflet suture are adjusted relative to the suture fastener to achieve a desired replacement chord length. The suture fastener is attached to the papillary suture and the leaflet suture to lock the desired replacement chord length.
摘要翻译：公开了一种外科缝合装置。手术缝合装置具有具有多个腿的叉形引导尖端，其中多个腿中的每一个包括近端，解剖变异和远端。还公开了一种用于心脏瓣膜的和弦更换方法。使用具有分叉引导尖端和乳头缝合线的手术缝合装置将缝合线放置在乳头肌中。小叶缝合线放置在传单中。乳头状缝合线和小叶缝合线以同轴方式从相反方向装载在缝合线紧固件中。乳头缝合线和/或小叶缝合线的长度相对于缝合线紧固件进行调节，以实现期望的替换弦长度。缝合紧固件连接到乳头缝合线和小叶缝合线以锁定期望的替换弦长度。

5. 发明申请

WO2016148714A1 TISSUE ANCHORS AND PERCUTANEOUS TRICUSPID VALVE REPAIR USING A TISSUE ANCHOR 审中-公开
标题翻译：使用组织锚固器的组织锚固器和胰腺三尖瓣修复
公开(公告)号：WO2016148714A1
公开(公告)日：2016-09-22
申请号：PCT/US2015/021346
申请日：2015-03-18
申请人： MITRALIGN, INC.
发明人： CAHALANE, Steven , ROBINSON, Jason , HOUSE, Morgan
IPC分类号： A61B17/04 , A61F2/24
CPC分类号： A61B17/0401 , A61B2017/00243 , A61B2017/00477 , A61B2017/00783 , A61B2017/00876 , A61B2017/0406 , A61B2017/0409 , A61B2017/0414 , A61B2017/0417 , A61B2017/0419 , A61B2017/0464 , A61F2/2445
摘要： The present teachings provide devices and methods of treating a tricuspid valve regurgitation. Specifically, one aspect of the present teachings provides devices and methods of identifying a suitable location on the tricuspid annulus, placing a wire across the tricuspid annulus at such an identified location, deploying a tissue anchor across such an identified location, deploying two or more tissue anchors and coupling the tissue anchors with a flexible tensioning member, and applying tension to a flexible tensioning member that is coupled with the two or more tissue anchors, plicating tissues between each pair of the two or more tissue anchors, and reducing the circumference of the tricuspid annuls. As a result, a regurgitation jet is reduced or eliminated.
摘要翻译：本教导提供治疗三尖瓣回流的装置和方法。具体而言，本教导的一个方面提供了鉴定三尖瓣环上的合适位置的装置和方法，将线穿过位于这样一个识别位置的三尖瓣环，在穿过这样的识别位置部署组织锚，展开两个或更多个组织将组织锚固件与柔性张紧构件联接并且将张力施加到与两个或更多个组织锚固件联接的柔性张紧构件上，在每对两个或多个组织锚固件之间修整组织，并且减小三尖瓣环结果，减少或消除了反流喷射。

6. 发明申请

WO2016126699A1 RAPID DEPLOYMENT ARTIFICIAL CHORDAE TENDINAE SYSTEM 审中-公开
标题翻译：快速部署人工犬腱系统
公开(公告)号：WO2016126699A1
公开(公告)日：2016-08-11
申请号：PCT/US2016/016156
申请日：2016-02-02
申请人： ON-X LIFE TECHNOLOGIES, INC.
发明人： MEDEMA, Ryan , SEELEY, Mark E.
IPC分类号： A61F2/24
CPC分类号： A61F2/2457 , A61B17/0401 , A61B17/06066 , A61B17/06166 , A61B2017/00539 , A61B2017/00946 , A61B2017/0406 , A61B2017/0409 , A61B2017/0417 , A61B2017/042 , A61B2017/06052 , A61B2017/061 , A61B2017/0619 , A61F2/2466 , A61F2210/0014 , A61F2250/0007
摘要： An embodiment includes an apparatus comprising: a hollow needle with a narrowed inner diameter in a distal third of the needle; and a flexible chord coupled to proximal and distal conduits; wherein the distal conduit is in the needle and distal to the narrowed inner diameter and the proximal conduit is in the needle and proximal to the narrowed inner diameter; wherein: (a)(i) long axes of the proximal and distal conduits are substantially parallel to a long axis of the needle when the proximal and distal conduits are in the needle, and (a)(ii) the proximal and distal conduits are configured to rotate when deployed from the needle such that their long axes are not parallel to a long axis of the chord when the chord is fully extended. Other embodiments are described herein.
摘要翻译：一个实施例包括一种装置，包括：在针的远端三分之一中具有变窄的内径的中空针; 以及耦合到近端和远端导管的柔性弦; 其中所述远端导管位于所述针中且远离所述变窄的内径，并且所述近侧导管位于所述针中并且接近所述变窄的内径; 其中：（a）（i）当近端和远端导管位于针中时，近端和远端导管的长轴基本上平行于针的长轴线，并且（a）（ii）近端和远端导管是配置成当从针展开时旋转，使得当弦完全伸展时，它们的长轴不平行于弦的长轴。本文描述了其它实施例。

7. 发明申请

WO2016025404A1 FISTULA TREATMENT DEVICES AND RELATED METHODS 审中-公开
标题翻译： FISTULA治疗装置及相关方法
公开(公告)号：WO2016025404A1
公开(公告)日：2016-02-18
申请号：PCT/US2015/044516
申请日：2015-08-10
申请人： CURASEAL INC.
发明人： CARRISON, Harold, F.
IPC分类号： A61B17/04
CPC分类号： A61B17/0057 , A61B17/0401 , A61B2017/00477 , A61B2017/00557 , A61B2017/00619 , A61B2017/00623 , A61B2017/00641 , A61B2017/00654 , A61B2017/00898 , A61B2017/00951 , A61B2017/0404 , A61B2017/0406 , A61B2017/0417 , A61B2017/0496 , A61B2017/320012 , A61B2217/005 , A61B2217/007
摘要： Disclosed herein are implantable fistula treatment devices and related methods. In some embodiments, an implantable fistula treatment device may comprise a suture and a proximal anchor. The proximal anchor may comprise a tissue anchor and a suture tensioner. The suture tensioner may be configured to resiliently maintain the suture in tension over a range of distances between the proximal anchor and a distal anchor. In some variations, the suture tensioner may have a deformable elastic structure. The suture tensioner may have a tensioned configuration and a neutral configuration.
摘要翻译：本文公开了可植入式瘘治疗装置和相关方法。在一些实施例中，可植入式瘘治疗装置可包括缝线和近端锚。近端锚可以包括组织锚和缝合线张紧器。缝合线张紧器可以被配置成在近端锚固件和远侧锚固件之间的距离范围内弹性地将缝合线保持在张力中。在一些变型中，缝合线张紧器可以具有可变形的弹性结构。缝合线张紧器可以具有张紧构型和中性构型。

8. 发明申请

WO2016011275A2 DEVICES AND METHODS FOR SUTURING A CARDIAC IMPLANT 审中-公开
标题翻译：用于治疗心脏移植物的装置和方法
公开(公告)号：WO2016011275A2
公开(公告)日：2016-01-21
申请号：PCT/US2015/040782
申请日：2015-07-16
申请人： EDWARDS LIFESCIENCES CORPORATION
发明人： MIRAKI, Manouchehr, A.
CPC分类号： A61B17/06004 , A61B17/06123 , A61B2017/0406 , A61B2017/06009 , A61F2/2409
摘要： Described herein are reusable surgical needles having a resiliently collapsible rear loop that captures a suture as it is passed through an object and resiliently expands upon exiting the object to release the suture. Also described are suture spool assemblies that comprise a rigid housing and a rotatable spool of suture material suspended within the housing so that a plurality of sutures can be dispensed from the assembly in succession during a surgery. Also described are annular pledgets having diametrical dimensions similar to an outer ring of a cardiac implant such that a single annular pledget can be used with a plurality of sutures that secure the cardiac implant to native tissue around the perimeter of the cardiac implant. Related methods of suturing cardiac implants are also disclosed.
摘要翻译：这里描述的是可重复使用的手术针，其具有弹性可折叠的后环，当缝合线穿过物体并且在离开物体时弹性地膨胀以释放缝线，捕获缝合线。还描述了缝合线轴组件，其包括刚性壳体和悬挂在壳体内的可旋转的缝合线卷轴，使得可以在手术期间连续地从组件分配多个缝合线。还描述了具有类似于心脏植入物的外环的直径尺寸的环形毛坯，使得单个环形绒毛可以与多个缝合线一起使用，所述缝合线将心脏植入物固定到心脏植入物的周边周围的天然组织。还公开了缝合心脏植入物的相关方法。

9. 发明申请

WO2015109243A1 METHOD AND APPARATUS FOR REPAIRING A MITRAL VALVE 审中-公开
标题翻译：修理一个阀门的方法和装置
公开(公告)号：WO2015109243A1
公开(公告)日：2015-07-23
申请号：PCT/US2015/011834
申请日：2015-01-16
申请人： MITRASPAN, INC.
发明人： ROURKE, Jonathan, M. , KYI, Stanley, B. , FISHMAN, Robert, B. , CHANG, Showna, H.
IPC分类号： A61B17/04 , A61F2/24
CPC分类号： A61F2/2442 , A61B17/0401 , A61B17/0467 , A61B17/0485 , A61B17/132 , A61B2017/00243 , A61B2017/00349 , A61B2017/00477 , A61B2017/00557 , A61B2017/00783 , A61B2017/0406 , A61B2017/0409 , A61B2017/0417 , A61B2017/045 , A61B2017/0464 , A61B2017/0477 , A61B2017/06104 , A61B2017/0649 , A61B2017/12004 , A61B2017/22038 , A61B2017/22044 , A61F2/2466 , A61F2/2487
摘要： Apparatus, the apparatus comprising: an anchor, the anchor comprising: an elongated body having a distal end and a proximal end, and a first side and a second side; a through-hole formed in the body intermediate the distal end and the proximal end and extending through the body from the first side to the second side, the through-hole being sized to receive a spanning suture; a proximal slot formed in the first side of the body and communicating with the through-hole, the proximal slot being sized to receive a spanning suture; and a distal slot formed in the second side of the body and communicating with the through-hole, the distal slot being sized to receive a spanning suture; at least a portion of the proximal slot being axially aligned with at least a portion of the distal slot so that the proximal slot, the through-hole and the distal slot together form an axial passageway extending from the distal end of the elongated body to the proximal end of the elongated body, with the axial passageway being sized to receive a spanning suture.
摘要翻译：一种装置，该装置包括：锚固件，该锚固件包括：细长体，其具有远端和近端，以及第一侧和第二侧; 在所述主体中形成的通孔在所述远端和所述近端的中间，并且从所述第一侧向所述第二侧延伸通过所述主体，所述通孔的尺寸被设计成接纳跨接缝线; 近端狭槽，其形成在所述主体的所述第一侧面中并且与所述通孔连通，所述近侧狭槽的尺寸被设计成接纳跨缝合线; 以及形成在所述主体的第二侧中且与所述通孔连通的远侧狭槽，所述远端狭槽的尺寸被设计成接纳跨缝合线; 所述近侧狭槽的至少一部分与所述远侧狭槽的至少一部分轴向对齐，使得所述近侧狭槽，所述通孔和所述远端狭槽一起形成从所述细长主体的远端延伸到所述远端狭槽的轴向通道细长体的近端，轴向通道的尺寸被设计成接纳跨缝合线。

10. 发明申请

WO2015066243A2 SYSTEM FOR PROVIDING SURGICAL ACCESS 审中-公开
标题翻译：用于提供手术通路的系统
公开(公告)号：WO2015066243A2
公开(公告)日：2015-05-07
申请号：PCT/US2014/063012
申请日：2014-10-29
申请人： ENTOURAGE MEDICAL TECHNOLOGIES, INC. , SHLUZAS, Alan, E. , DIAZ, Stephen, H.
发明人： SHLUZAS, Alan, E. , DIAZ, Stephen, H.
IPC分类号： A61B17/04
CPC分类号： A61B17/0469 , A61B17/0057 , A61B17/0401 , A61B2017/00004 , A61B2017/00022 , A61B2017/00349 , A61B2017/00575 , A61B2017/00623 , A61B2017/00663 , A61B2017/00862 , A61B2017/00871 , A61B2017/00884 , A61B2017/0403 , A61B2017/0404 , A61B2017/0406 , A61B2017/0408 , A61B2017/0409 , A61B2017/0417 , A61B2017/0446 , A61B2017/0448 , A61B2017/0464 , A61B2017/0495 , A61B2017/0496 , A61B2017/06076 , A61B2017/06171 , A61B2017/06176 , A61B2017/22069 , A61B2090/065
摘要： One embodiment is directed to a system for closing a wound created across a portion of a tissue structure, comprising a suture member having proximal and distal ends; an anchor member coupled to the distal end of the suture member; a tension retainer assembly releasably coupleable to the suture member; and a suture buttress movably intercoupled to the suture member between the anchor member and the tension retainer and configured to minimize direct sliding contact between the suture member and the tissue structure portion around the location of the suture buttress.
摘要翻译：一个实施例涉及一种用于闭合在组织结构的一部分上创建的伤口的系统，该系统包括具有近端和远端的缝合线构件; 联接到缝合线构件的远端的锚定构件; 可释放地连接至所述缝合线构件的张力保持器组件; 以及缝合支柱，该缝合支柱与锚定构件和张力保持器之间的缝合线构件可移动地相互连接并且被配置为最小化缝合线构件和缝合线支撑物位置周围的组织结构部分之间的直接滑动接触。

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