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1. 发明申请

WO2011053661A1 METHOD AND APPARATUS FOR MAGNETIC INDUCTION THERAPY 审中-公开
标题翻译：用于磁感应治疗的方法和装置
公开(公告)号：WO2011053661A1
公开(公告)日：2011-05-05
申请号：PCT/US2010/054353
申请日：2010-10-27
申请人： EMKINETICS, INC. , BURNETT, Daniel, R. , HERMANSON, Christopher
发明人： BURNETT, Daniel, R. , HERMANSON, Christopher
IPC分类号： A61N1/00
CPC分类号： A61N2/006 , A61N1/08 , A61N2/02
摘要： Energy emitting systems are provided which include an adjustable conductive coil configured to generate a magnetic or electromagnetic field focused on a target nerve. The coil includes a central aperture which may be adjustable between a first configuration and a second configuration having a radius greater than the radius of the first configuration. The adjustable or movable nature of the coil allows the conductive coil to conform to, accommodate, or be positioned on a particular anatomical structure of a patient to position the coil in proximity to the underlying target nerve. In certain embodiments, methods of magnetic induction therapy are provided which include positioning a conductive coil relative to a portion of a patient's body by adjusting the central aperture of the coil such that the coil may conform to, accommodate or be positioned on the portion of the patient's body in proximity to the underlying target nerve.
摘要翻译：提供能量发射系统，其包括被配置为产生聚焦在目标神经上的磁场或电磁场的可调导电线圈。线圈包括可以在第一配置和第二配置之间可调节的中心孔，其具有大于第一配置的半径的半径。线圈的可调节或可移动的性质允许导电线圈符合，适应或定位在患者的特定解剖结构上，以将线圈定位在接近下面的目标神经。在某些实施例中，提供了磁感应治疗的方法，其包括通过调节线圈的中心孔来相对于患者身体的一部分定位导电线圈，使得线圈可以符合，适应或定位在患者身体的一部分上患者的身体靠近潜在的目标神经。

2. 发明申请

WO2008042902A3 METHOD AND APPARATUS FOR MAGNETIC INDUCTION THERAPY 审中-公开
公开(公告)号：WO2008042902A3
公开(公告)日：2008-04-10
申请号：PCT/US2007/080196
申请日：2007-10-02
申请人： EMKINETICS, INC. , BURNETT, Daniel, R. , HERMANSON, Christopher
发明人： BURNETT, Daniel, R. , HERMANSON, Christopher
IPC分类号： A61N2/00
摘要： An energy emitting apparatus for providing a medical therapy includes one or more energy generators, a logic controller electrically connected to the one or more energy generators, and one or more sensors for detecting electric conduction in a target nerve that are connected to the logic controller. The one or more energy generators produce energy focused on the target nerve upon receiving a signal from the logic controller, and the energy is varied by the logic controller according to an input provided by the one or more sensors. In one embodiment, the energy emitting apparatus is an apparatus for magnetic induction therapy that includes one or more conductive coils disposed in an ergonomic housing that produce a magnetic field focused on the target nerve upon receiving an electric current from the logic controller based on an input provided by the one or more sensors.

3. 发明申请

WO2006135857A2 METHOD AND APPARATUS FOR MONITORING IMPLANTS 审中-公开
标题翻译：用于监控植入物的方法和装置
公开(公告)号：WO2006135857A2
公开(公告)日：2006-12-21
申请号：PCT/US2006/022761
申请日：2006-06-12
申请人： THERANOVA LLC , MANGRUM, Shane, C. , BURNETT, Daniel, R. , JOHNSON, Noel, L.
发明人： MANGRUM, Shane, C. , BURNETT, Daniel, R. , JOHNSON, Noel, L.
IPC分类号： A61F2/12
CPC分类号： A61F2/12 , A61B5/6846 , A61F2250/0002
摘要： The present invention involves a device and method that communicate, to a patient and/or healthcare professionals, the failure, rupture, or breakage of a barrier within an implant. The device consists of an implantable sensor and an alerting mechanism. The device may include an internal power source and may employ software to allow for external programming and/or interrogation of the device. The device may also be recharged and/or powered through an external source.
摘要翻译：本发明涉及一种向患者和/或保健专业人员传递植入物内的屏障的故障，破裂或断裂的装置和方法。该装置由可植入传感器和警报机构组成。该设备可以包括内部电源，并且可以使用软件来允许设备的外部编程和/或询问。该装置还可以通过外部源再充电和/或供电。

4. 发明申请

WO2006047708A2 MEDICAL DEVICE DELIVERY CATHETER 审中-公开
标题翻译：医疗器械输送管
公开(公告)号：WO2006047708A2
公开(公告)日：2006-05-04
申请号：PCT/US2005/038842
申请日：2005-10-25
申请人： MEDVENTURE ASSOCIATES IV , BURNETT, Daniel, R. , HALL, Gregory, W. , BAJOR, Jordan, T. , FISHER, Winfield, Scott , HITES, Tibor, Laszlo
发明人： BURNETT, Daniel, R. , HALL, Gregory, W. , BAJOR, Jordan, T. , FISHER, Winfield, Scott , HITES, Tibor, Laszlo
IPC分类号： A61B17/00
CPC分类号： A61F2/95 , A61B17/12099 , A61B17/12159 , A61B2017/12054 , A61B2017/12059 , A61B2017/12081 , A61B2090/037 , A61F2/88 , A61F2/97 , A61F5/0079 , A61F2002/044 , A61F2002/9511
摘要： Apparatus for delivering a medical device to a location in a patient's body includes an elongate catheter body having a proximal end and a distal end, a pod coupled with the distal end of the catheter body and adapted to house the medical device during delivery to the location and to open to release the medical device, and at least one distal actuator coupled with at least one of the pod and the medical device. The distal actuator is adapted to promote opening of the pod. A method involves advancing a pod at the distal end of an elongate catheter to the location within the body and activating an actuator coupled with the pod and/or the medical device to cause the pod to open. Opening the pod releases the medical device.
摘要翻译：用于将医疗装置递送到患者体内的位置的装置包括具有近端和远端的细长导管主体，与导管主体的远端联接的适配器，用于在输送到位置期间容纳医疗装置并且打开以释放所述医疗装置，以及至少一个与所述容器和所述医疗装置中的至少一个联接的远端致动器。远侧致动器适于促进荚的打开。一种方法包括将细长导管的远端处的囊推进到体内的位置，并启动与荚和/或医疗装置连接的致动器以使荚打开。打开荚释放医疗器械。

5. 发明申请

WO2006020370A2 DEVICES AND METHODS FOR PYLORIC ANCHORING 审中-公开
标题翻译：用于垂直锚定的装置和方法
公开(公告)号：WO2006020370A2
公开(公告)日：2006-02-23
申请号：PCT/US2005/026370
申请日：2005-07-25
申请人： POLYMORFIX, INC. , BURNETT, Daniel, R. , HALL, Gregory, W. , CAMPBELL-WHITE, Annette , BAJOR, Jordan, T.
发明人： BURNETT, Daniel, R. , HALL, Gregory, W. , CAMPBELL-WHITE, Annette , BAJOR, Jordan, T.
IPC分类号： A61B17/08
CPC分类号： A61F5/0079 , A61B5/036 , A61B5/073 , A61B5/145 , A61B5/14539 , A61B5/14546 , A61B5/4238 , A61B17/12022 , A61B17/12036 , A61B17/12099 , A61B17/12136 , A61B17/12172 , A61B17/1219 , A61B2017/00876 , A61B2017/12054 , A61B2017/12086 , A61F2/24 , A61F5/003 , A61F5/0036 , A61F2002/044 , A61N1/06 , A61N1/40
摘要： A device for performing one or more functions in a gastrointestinal tract of a patient includes an anchoring member and at least one actuator, sensor, or combination of both coupled with the anchoring device. The anchoring device is adapted to maintain at least part of the device within a pyloric portion of the patient's stomach and to intermittently engage, without directly attaching to, stomach tissue. Actuators perform any suitable function, such as transmitting energy to tissue, acting as a sleeve to reduce nutrient absorption, occupying space in the stomach, eluting a drug and/or the like. Sensors may be adapted to sense any suitable patient characteristic within the patient's gastrointestinal tract, such as pH, temperature, bile content, nutrient content, fats, sugars, alcohol, opiates, drugs, analytes, electrolytes and/or hemoglobin.
摘要翻译：用于在患者的胃肠道中执行一个或多个功能的装置包括锚定构件和至少一个致动器，传感器或两者的组合，其与锚定装置联接。锚定装置适于将装置的至少一部分保持在患者胃的幽门部分内，并间歇地接合，而不直接附着于胃组织。致动器执行任何合适的功能，例如将能量传递到组织，用作套筒以减少营养吸收，占据胃中的空间，洗脱药物等。传感器可以适于感测患者胃肠道内的任何合适的患者特征，例如pH，温度，胆汁含量，营养成分，脂肪，糖，酒精，阿片剂，药物，分析物，电解质和/或血红蛋白。

6. 发明申请

WO2009023818A1 METHOD AND APPARATUS FOR AUTOMATED ACTIVE STERILIZATION OF FULLY IMPLANTED DEVICES 审中-公开
标题翻译：用于自动主动灭菌完全植入装置的方法和装置
公开(公告)号：WO2009023818A1
公开(公告)日：2009-02-19
申请号：PCT/US2008/073279
申请日：2008-08-15
申请人： THERANOVA, LLC , BURNETT, Daniel, R.
发明人： BURNETT, Daniel, R.
IPC分类号： A61L2/00
CPC分类号： A61M25/0017 , A61F2/042 , A61F2/82 , A61L2/02 , A61L2/025 , A61L2/08 , A61L2/10 , A61L2/12 , A61L2/18 , A61M5/142 , A61M2025/0056 , A61M2205/0205 , A61M2205/051 , A61M2205/054 , A61M2205/058
摘要： The current invention provides this advance in infection control via its unique application of active sterilization to a catheter or implant. While most catheters, and many implants, are passive devices, the current invention will provide an active component as a integral part of the implanted catheter or device to continuously or intermittently sterilize the exposed surfaces/areas of the device. This active sterilization may be accomplished by a variety of mechanisms, including, application of heat, RF, microwave, ultrasound, ultraviolet radiation or other energy capable of sterilizing the device or dislodging any problematic biofilm that may form. The active sterilization may also employ the pumping of a sterilizing chemical from an attached drug reservoir, the use of electricity or freezing temperatures or any other mechanism for either inhibiting, killing or dislodging any infection material in contact with the implant.
摘要翻译：本发明通过其对导管或植入物的主动消毒的独特应用来提供感染控制方面的进步。虽然大多数导管和许多植入物是无源器件，但是本发明将提供作为植入的导管或装置的组成部分的有源部件，以连续或间歇地对设备的暴露表面/区域进行灭菌。这种有效的灭菌可以通过多种机制来实现，包括应用热，RF，微波，超声波，紫外线辐射或其他能够对装置进行灭菌或排除可能形成的任何有问题的生物膜的能量。活性灭菌还可以使用从连接的药物储存器中泵送灭菌化学品，使用电力或冷冻温度或任何其他机制来抑制，杀死或移除与植入物接触的任何感染材料。

7. 发明申请

WO2007027812A3 GASTRIC RETAINING DEVICES AND METHODS 审中-公开
公开(公告)号：WO2007027812A3
公开(公告)日：2007-03-08
申请号：PCT/US2006/033923
申请日：2006-08-29
申请人： BARONOVA, INC. , BURNETT, Daniel, R. , HALL, Greg , GALLUP, David, A.
发明人： BURNETT, Daniel, R. , HALL, Greg , GALLUP, David, A.
IPC分类号： A61F2/04 , A61B17/08 , A61F2/00
摘要： Devices and methods are disclosed that facilitate gastric retention. In one embodiment of the present invention, a gastric device includes a support portion for preventing the device from passing through the pyloric valve or esophagus, and an optional retaining member for maintaining a position in the stomach. The device may be deliverable into the stomach through the esophagus, either by swallowing or through a delivery tube or catheter, and may be fully reversible. In another embodiments, a gastric device according to the present invention self-expands within the stomach, while in still another embodiments a gastric device is inflatable or otherwise expandable.

8. 发明申请

WO2005018708A2 MAGNETIC CIRCUMFERENTIALLY COUPLED IMPLANTABLE PUMP 审中-公开
标题翻译：磁性圆形连接可植入泵
公开(公告)号：WO2005018708A2
公开(公告)日：2005-03-03
申请号：PCT/US2004/026781
申请日：2004-08-18
申请人： THERANOVA, LLC , BURNETT, Daniel, R.
发明人： BURNETT, Daniel, R.
IPC分类号： A61M
CPC分类号： A61K9/0009 , A61K9/0024 , A61M5/14276 , A61M2205/8287
摘要： A magnetic circumferentially-coupled implantable pump is disclosed herein. A magnetically coupled implantable actuation system utilizes a magneticallyt-coupled drive mechanism configured to generate power for implantable medical devices. One variation generally comprise a drive magnet having a first radius and adapted to rotate about a longitudinal axis when urged, and a driven magnet defining a second radius, which is less than the first radius. This driven magnet is adapted to be implanted within a body rotate about the longitudinal axis when coaxially positioned within a receiving cavity defined by the drive magnet such that magnetic coupling occurs circurnferentially between the driven magnet and the drive magnet. Another variation utilizes elongate bar magnets configured to rotate about a pivot. An optional anchor can be used to secure the implanted driven magnet housing against any rotational forces or moments by securing the housing within the subcutaneous layer.
摘要翻译：本文公开了一种磁性圆周耦合可植入泵。磁耦合可植入致动系统利用配置成为可植入医疗装置产生电力的磁耦合驱动机构。一个变型通常包括具有第一半径并且适于在被推动时围绕纵向轴线旋转的驱动磁体以及限定小于第一半径的第二半径的从动磁体。当被驱动磁体同轴地位于由驱动磁体限定的接收腔内时，该驱动磁体适于被植入体内围绕纵向轴线旋转，使得磁耦合在从动磁体和驱动磁体之间周向发生。另一种变型使用配置成围绕枢轴旋转的细长杆状磁体。可选的锚固件可用于通过将壳体固定在皮下层内来固定植入的从动磁体壳体抵抗任何旋转力或力矩。

9. 发明申请

WO2005009288A3 PYLORIC VALVE OBSTRUCTING DEVICES AND METHODS 审中-公开
公开(公告)号：WO2005009288A3
公开(公告)日：2005-02-03
申请号：PCT/US2004/023470
申请日：2004-07-20
申请人： POLYMORFIX, INC. , BURNETT, Daniel, R. , HALL, Greg , RICHMAN, Roxanne , GALLUP, David, A. , CAMPBELL-WHITE, Annette
发明人： BURNETT, Daniel, R. , HALL, Greg , RICHMAN, Roxanne , GALLUP, David, A. , CAMPBELL-WHITE, Annette
IPC分类号： A61F2/04
摘要： Methods, devices and systems facilitate intermittent and/or partial obstruction of a pyloric valve. Devices generally include a support portion (16) for preventing the device from passing through the pyloric valve and a tissue engagement portion for contacting tissue adjacent the pyloric valve to obstruct the valve. Some embodiments also include a positioning member extending from the tissue engagement portion for helping position the device for obstructing the valve. A retaining member (210) may optionally be included on the distal end of the positioning member for further maintaining a position of the device in the stomach (74). Some embodiments are deliverable into the stomach through the esophagus (78), either by swallowing or through a delivery tube or catheter (8). Some embodiments are fully reversible. Some embodiments self-expand within the stomach, while others are inflated or otherwise expanded.

10. 发明申请

WO2007092501A3 GASTRO-INTESTINAL DEVICE AND METHOD FOR TREATING ADDICTION 审中-公开
公开(公告)号：WO2007092501A3
公开(公告)日：2007-08-16
申请号：PCT/US2007/003260
申请日：2007-02-05
申请人： BARONOVA, INC. , BURNETT, Daniel, R.
发明人： BURNETT, Daniel, R.
IPC分类号： A61B17/08
摘要： A device and a method for treating a medical condition include a reversible member disposed in a patient's gastro-intestinal tract, and a dispensing member coupled to the reversible member that delivers a drug and/or a noxious when a predetermined substance is detected. In a different embodiment, the device and method of the present invention include a polymer infused with a drug and disposed into a preformed shell inside the gastric space, where it expands and hardens, releasing the drug over time. Both the casing and the polymer may be biocompatible. The present invention enables the slow-release of anti-addictive agents without patient tampering and with the appropriate dosage. Ancillary systems such as sensors, actuators, refill and recharge ports, and communication and data processing units may also be included.

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