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1. 发明申请

WO2019155326A1 TISSUE EXPANDER 审中-公开
公开(公告)号：WO2019155326A1
公开(公告)日：2019-08-15
申请号：PCT/IB2019/050786
申请日：2019-01-31
申请人： ETHICON, INC.
发明人： KIRCHHEVEL, Gordon Lamar , TAFFE, David Henry
IPC分类号： A61F2/12 , A61B90/00 , A61B17/00
CPC分类号： A61B90/02 , A61B2017/00539 , A61B2017/00557 , A61B2017/00792 , A61B2017/00796 , A61B2017/00876 , A61F2/12 , A61M5/178 , A61M39/02 , A61M2039/0205 , A61M2039/027 , A61M2039/0276
摘要： A tissue expander is disclosed herein. The tissue expander may comprise a shell defining a chamber, and having a flexible wall and a port disposed through the flexible wall. The shell may also include a channel disposed through the flexible wall. A first syringe containing a first volume of a liquid may be connected to the chamber of the tissue expander via the channel. A second syringe containing a second volume of the liquid may be connected to the chamber via the port at least approximately one week after the first volume of liquid is injected. The first volume of liquid may be injected more quickly than the second volume of liquid.

2. 发明申请

WO2017221172A2 PROCESS FOR PRODUCING A MEDICAL DEVICE WHICH IS COATED WITH A THIN FILM BASED ON CARBON AND MEDICAL DEVICE WHICH CAN BE OBTAINED BY MEANS OF THIS PROCESS 审中-公开
标题翻译：用碳膜包裹薄膜的医疗器械的制造方法以及通过该方法得到的医疗器械
公开(公告)号：WO2017221172A2
公开(公告)日：2017-12-28
申请号：PCT/IB2017/053698
申请日：2017-06-21
申请人： ARCHIMEDES S.R.L.
发明人： ORNAGHI, Oscar Marco , BINOTTO, Radames
IPC分类号： A61F2/12 , A61F2/00 , A61L33/02 , A61L27/30 , C23C14/06 , C23C14/22 , C23C14/35 , C23C14/50
CPC分类号： A61F2/12 , A61F2/0063 , A61F2240/001 , A61L27/303 , A61L2420/02 , A61L2430/04 , C23C14/0605 , C23C14/35 , C23C14/505
摘要： A process for producing a medical device (100), which is coated with a thin film based on carbon, comprises the steps of: - positioning a medical device to be coated inside a processing chamber (3), in which there is provided a target element (10) of carbon; reducing the pressure in the processing chamber until reaching a residual pressure between 10 -4 Pa and 10 -3 Pa; starting in the processing chamber a physical vapour deposition step in which a group of ions is accelerated against the target element so as to cause the projection of carbon atoms towards the medical device; maintaining the physical vapour deposition step for a predefined time so as to deposit on the medical device a coating of a thin film of turbostratic carbon having a thickness between 100 nm and 1000 nm.
摘要翻译：一种制造涂覆有基于碳的薄膜的医疗装置（100）的方法，包括以下步骤： - 将待涂敷的医疗装置定位在处理腔室（3）内部，其中提供了碳的目标元素（10）; 减小处理室中的压力直到达到10 -4 Pa和10 -3 Pa之间的残余压力; 在处理室中开始物理气相沉积步骤，在该步骤中，一组离子加速撞击目标元件，从而引起碳原子朝向医疗装置的投影; 将物理气相沉积步骤保持预定时间，以便在医疗装置上沉积厚度在100nm和1000nm之间的乱层碳薄膜的涂层。

3. 发明申请

WO2017100713A1 HUMAN NIPPLE AREOLAR COMPLEX EXTRACELLULAR MATRIX SCAFFOLD AND METHODS RELATING THERETO 审中-公开
标题翻译：人类痣区域复杂的细胞外基质支架及其与其相关的方法
公开(公告)号：WO2017100713A1
公开(公告)日：2017-06-15
申请号：PCT/US2016/066024
申请日：2016-12-09
申请人： NOVOTHELIUM, LLC
发明人： CERQUEIRA, Bianca G. , CORNELL, Lauren E.
IPC分类号： A61F2/12
CPC分类号： A61L27/3633 , A61F2/12 , A61L27/3666 , A61L27/3687 , A61L27/3869 , A61L2430/04
摘要： Methods of producing and methods of treatment using a nipple areolar complex extracellular matrix. A method for processing tissue comprises harvesting a human nipple areolar complex tissue, treating the tissue with a stabilizing medium, wherein the medium stabilizes the tissue during transport, decellularizing the tissue, and sterilizing the tissue to form a human nipple areolar complex extracellular matrix scaffold (ECMS). A method of treating an individual with a need for a nipple reconstruction comprises forming an ECMS and applying the ECMS to the individual for nipple areolar regeneration.
摘要翻译：使用乳头乳晕复合体细胞外基质的治疗方法和治疗方法用于处理组织的方法包括收获人乳头乳晕复合组织，用稳定介质处理组织，其中所述介质在运输期间稳定组织，使组织脱细胞化，并且消毒组织以形成人乳头乳晕复合细胞外基质支架（ ECMS）。治疗需要乳头重建的个体的方法包括形成ECMS并将ECMS应用于个体用于乳头乳晕再生。

4. 发明申请

WO2016186803A1 TISSUE MATRICES FOR PLASTIC SURGERY 审中-公开
标题翻译：塑料手术的组织矩阵
公开(公告)号：WO2016186803A1
公开(公告)日：2016-11-24
申请号：PCT/US2016/029411
申请日：2016-04-27
申请人： LIFECELL CORPORATION
发明人： WANG, Kai-Roy , PARK, Sangwook , BARERE, Aaron
IPC分类号： A61F2/12
CPC分类号： A61F2/0063 , A61B90/02 , A61F2/12 , A61F2002/0068 , A61F2220/0008 , A61F2220/0075 , A61L27/3666 , A61L2430/04
摘要： Methods, systems, and compositions for treatment are provided. The methods can be used to stretch and completely or nearly completely wrap a composition around an implant or tissue expander. The systems can be used to protect an implant or tissue expander by completely or nearly completely wrapping a composition around the implant or tissue expander. The compositions can be used to completely or nearly completely wrap around an implant or tissue expander to provide support and protection to the implant or tissue expander.
摘要翻译：提供了用于治疗的方法，系统和组合物。该方法可用于拉伸和完全或几乎完全包裹植入物或组织扩张器周围的组合物。该系统可用于通过将组合物完全或几乎完全包裹在植入物或组织扩张器周围来保护植入物或组织扩张器。组合物可用于完全或几乎完全包裹植入物或组织扩张器，以为植入物或组织扩张器提供支撑和保护。

5. 发明申请

WO2016172094A1 ABSORBABLE IMPLANTS FOR PLASTIC SURGERY 审中-公开
标题翻译：用于塑料手术的可吸收植入物
公开(公告)号：WO2016172094A1
公开(公告)日：2016-10-27
申请号：PCT/US2016/028264
申请日：2016-04-19
申请人： TEPHA, INC.
发明人： LIMEM, Skander , STIRES, Emily , HOLMES, Rebecca , RIZK, Said , MOSES, Arikha , FELIX, Fabio , VAN NATTA, Bruce
IPC分类号： A61F2/00 , A61F2/12
CPC分类号： A61F2/12 , A61F2/0059 , A61F2/0063 , A61F2210/0004 , A61F2230/0076 , A61F2240/001 , A61L27/18 , A61L2430/04 , C08L67/04
摘要： Absorbable implants (200) for breast surgery that conform to the breast parenchyma and surrounding chest wall have been developed. These implants support newly lifted breast parenchyma, and/or a breast implant. The implants have mechanical properties sufficient to support a reconstructed breast, and allow the in-growth of tissue into the implant as it degrades. The implants have a strength retention profile allowing the support of the breast to be transitioned from the implant to regenerated host tissue, without significant loss of support. Three-dimensional implants for use in minimally invasive mastopexy/ breast reconstruction procedures are also described, that confer shape to a patient's breast. These implants are self-reinforced, can be temporarily deformed, implanted in a suitably dissected tissue plane, and resume their preformed three-dimensional shape. The implants are preferably made from poly-4-hydroxybutyrate (P4HB) and copolymers thereof. The implants have suture pullout strengths that can resist the mechanical loads exerted on the reconstructed breast.
摘要翻译：已经开发出符合乳房实质和周围胸壁的乳房手术的可吸收植入物（200）。这些植入物支持新提起的乳腺实质和/或乳房植入物。植入物具有足以支撑重建的乳房的机械性能，并且当植入物降解时允许组织进入植入物。植入物具有强度保持特征，允许乳房的支撑从植入物过渡到再生的宿主组织，而没有显着的支撑损失。还描述了用于微创乳突肌肉/乳房重建手术的三维植入物，其赋予患者乳房的形状。这些植入物是自增强的，可以暂时变形，植入合适的解剖组织平面，并恢复其预先形成的三维形状。植入物优选由聚-4-羟基丁酸酯（P4HB）及其共聚物制成。植入物具有可以抵抗施加在重建的乳房上的机械负荷的缝合拉拔强度。

6. 发明申请

WO2016160952A1 FLUID-FILLED IMPLANTABLE STRUCTURES WITH INTERNAL SURFACE-MODIFYING COMPONENTS AND RELATED METHODS 审中-公开
标题翻译：具有内表面修饰组分的流体填充可植入结构及相关方法
公开(公告)号：WO2016160952A1
公开(公告)日：2016-10-06
申请号：PCT/US2016/024960
申请日：2016-03-30
申请人： SHI, Wendian , DEBOER, Charles , TAI, Yu-Chong , LEE, Jonathan, K. , RIBEIRO, Ramiro, Magalhaes , HUMAYUN, Mark, S.
发明人： SHI, Wendian , DEBOER, Charles , TAI, Yu-Chong , LEE, Jonathan, K. , RIBEIRO, Ramiro, Magalhaes , HUMAYUN, Mark, S.
IPC分类号： A61F2/16 , A61L27/14
CPC分类号： A61F2/1601 , A61F2/12 , A61F9/0017 , A61F2002/1699 , A61F2230/0071 , A61F2240/001 , A61F2250/0014
摘要： Implantable reservoir structures include an interior and/or exterior modifying element joined to the interior and/or exterior surface of the membrane defining the reservoir in order to alter one or more physical properties thereof. The physical properties can be mechanical (e.g., material strength, flexibility, shear modulus, Young's modulus, hardness, and/or ductility); optical (e.g., refraction, transparency, transmission spectrum, absorption spectrum, fluorescence spectrum, and/or color); and/or permeability to liquids generally or to a particular type of liquid, solute, or suspended material.
摘要翻译：可植入储存器结构包括连接到限定储存器的膜的内部和/或外表面的内部和/或外部修改元件，以便改变其一个或多个物理性质。物理性能可以是机械的（例如，材料强度，柔韧性，剪切模量，杨氏模量，硬度和/或延展性）; 光学（例如折射，透明度，透射光谱，吸收光谱，荧光光谱和/或颜色）; 和/或液体的通透性或特定类型的液体，溶质或悬浮物质的渗透性。

7. 发明申请

WO2016123554A1 GLUTEAL IMPLANTS AND IMPLANT SYSTEMS 审中-公开
标题翻译： GLUTEAL IMPLANTS和IMPLANT SYSTEMS
公开(公告)号：WO2016123554A1
公开(公告)日：2016-08-04
申请号：PCT/US2016/015787
申请日：2016-01-29
申请人： RYAN A. STANTON, M.D., INC.
发明人： STANTON, Ryan, A.
IPC分类号： A61F2/02 , A61F2/08
CPC分类号： A61F2/0059 , A61F2/12 , A61F2220/0033 , A61F2230/0008 , A61F2230/0093 , A61F2250/0062
摘要： Gluteal implants and gluteal implant systems are described herein, as are methods of manufacturing and implanting the same. In certain embodiments, the gluteal implant includes a body having a convex upper surface, a concave lower surface, and an edge, the edge being formed by the intersection between the convex upper surface and the concave lower surface. The body can take on various shapes, including a truncated ovoid shape, a truncated approximate ovoid shape, a truncated substantially ovoid shape, a truncated ellipsoid shape, a truncated approximate ellipsoid shape, or a truncated substantially ellipsoid shape, among others. In certain embodiments, the gluteal implant system includes first and second gluteal implants that have the same or different shaped bodies. In certain embodiments, the gluteal implants and gluteal implant systems are implanted in a buttock region.
摘要翻译：本文描述了臀部植入物和臀部植入物系统，制造和植入它们的方法也是如此。在某些实施例中，臀部植入物包括具有凸上表面，凹下表面和边缘的主体，该边缘由凸上表面和凹下表面之间的交点形成。身体可以具有各种形状，包括截顶的卵形，截短的近似卵形，截短的大致卵形，截短的椭圆形，截短的近似椭圆形或截短的大致椭圆形等。在某些实施例中，臀部植入系统包括具有相同或不同成形体的第一和第二臀部植入物。在某些实施例中，臀部植入物和臀部植入物系统植入臀部区域。

8. 发明申请

WO2016108228A1 HUMAN IMPLANTABLE TISSUE EXPANDERS 审中-公开
标题翻译：人造革组织扩张器
公开(公告)号：WO2016108228A1
公开(公告)日：2016-07-07
申请号：PCT/IL2015/051257
申请日：2015-12-28
申请人： IMPLITE LTD.
发明人： GLICKSMAN, Ami
IPC分类号： A61F2/12
CPC分类号： A61F2/02 , A61F2/08 , A61F2/12 , A61F2002/0894 , A61F2210/0076
摘要： Human implantable tissue expanders are provided, such as breast tissue expanders, that comprise an inner foam filling enclosed within a liquid-filled compartment and further within a sealing shell comprising a substantially non-stretchable resilient expansion restricting layer. The substantially non-stretchable resilient expansion restricting layer is configured to retain a shape and/or volume of said foam filling upon changes of ambient pressure and/or temperature.
摘要翻译：提供人类植入式组织扩张器，例如乳房组织扩张器，其包括封闭在充满液体的隔室内的进一步包括基本上不可拉伸的弹性膨胀限制层的密封壳内的内泡沫填充物。基本上不可拉伸的弹性膨胀限制层构造成在环境压力和/或温度变化时保持所述泡沫填充物的形状和/或体积。

9. 发明申请

WO2016077160A1 IMMERSION CURING PROCESS 审中-公开
标题翻译：倾斜固化过程
公开(公告)号：WO2016077160A1
公开(公告)日：2016-05-19
申请号：PCT/US2015/059383
申请日：2015-11-06
申请人： APPLIED SILICONE COMPANY , WINN, R., Alastair , PASKO, Nolan
发明人： WINN, R., Alastair , PASKO, Nolan
IPC分类号： A61F2/12
CPC分类号： B29C35/041 , A61F2/12 , A61F2240/00 , B29C41/003 , B29C41/14 , B29C2035/042 , B29C2059/028 , B29K2083/005 , B29L2031/7532
摘要： A system and method for manufacture of prosthesis shells using a hot liquid bath to cure the shells is described. The shell is formed on a mold or mandrel, and is then immersed in a hot liquid bath to cure the shell material. Multiple layers of material, such a silicone, may be formed by immersing the layer into a hot liquid bath, cooling the cured layer, applying another layer of uncured material to the cured layer, and then curing the uncured layer in a hot liquid bath. A textured surface may be imparted to the shell by incorporating a texture component into the last layer formed, such that immersing the uncured layer incorporating the texture component in the hot liquid bath cures the last layer formed and dissolves the texture component.
摘要翻译：描述了使用热液浴来制造用于固化壳的假体壳的系统和方法。壳体形成在模具或心轴上，然后将其浸入热液浴中以固化壳材料。可以通过将层浸入热液浴中，冷却固化层，将另一层未固化的材料施加到固化层，然后在热液浴中固化未固化层来形成多层材料，例如硅氧烷。可以通过将纹理组分并入形成的最后层中来赋予壳体的纹理表面，使得将包含织构组分的未固化层浸入热液浴中固化形成的最后层并溶解织构组分。

10. 发明申请

WO2015196184A3 METHODS AND DEVICES FOR BREAST IMPLANT SURGERY AND SELECTION 审中-公开
标题翻译：用于乳腺移植手术和选择的方法和装置
公开(公告)号：WO2015196184A3
公开(公告)日：2016-03-03
申请号：PCT/US2015036860
申请日：2015-06-22
申请人： TANTILLO MICHAEL
发明人： TANTILLO MICHAEL
IPC分类号： A61F2/12
CPC分类号： B29C67/0088 , A61F2/12 , A61F2230/0006 , A61F2230/0008 , A61F2230/0015 , A61F2240/001 , A61F2240/002 , A61F2240/005 , A61F2240/007 , B29C64/386 , B33Y10/00 , B33Y30/00 , B33Y50/02 , B33Y80/00
摘要： The present disclosure provides several processes, algorithms, and devices for breast implant surgery. An algorithm of the present disclosure can receive input from a user, surgeon, patient, and determine an appropriate or desired implant size or shape. The algorithm can prompt the user for adjustment and/or prioritization of certain parameters, and adjust the implant determination accordingly. Two-dimensional (2D) sizers of the present disclosure can be used during implant surgery to assist in determining an appropriate amount of pocket dissection. The 2D sizers can be inserted into a partially dissected cavity to determine whether the cavity is the correct size, and the doctor can then perform more dissection if needed. The processes and devices of the present disclosure can also be used with other imaging devices and a printer to provide implants on site.
摘要翻译：本公开提供用于乳房植入手术的几种过程，算法和装置。本公开的算法可以从用户，外科医生，患者接收输入，并且确定适当或期望的植入物大小或形状。该算法可以提示用户对某些参数进行调整和/或优先排序，并相应地调整植入物确定。可以在植入手术期间使用本公开的二维（2D）分级器，以帮助确定适当量的口袋解剖。 2D尺寸调节器可以插入到部分解剖的腔中，以确定腔体是否是正确的尺寸，然后如果需要，医生可以执行更多的解剖。本公开的方法和装置还可以与其他成像装置和打印机一起使用以在现场提供植入物。

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