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1. 发明申请

WO2018022674A1 COMPACT DETECTION MODULE FOR FLOW CYTOMETERS 审中-公开
标题翻译：用于流式细胞仪的紧凑型检测模块
公开(公告)号：WO2018022674A1
公开(公告)日：2018-02-01
申请号：PCT/US2017/043815
申请日：2017-07-25
申请人： CYTEK BIOSCIENCES, INC. , YAN, Ming , HSIEH, Yung-Chieh , VRANE, David , CHASE, Eric
发明人： YAN, Ming , HSIEH, Yung-Chieh , VRANE, David , CHASE, Eric
IPC分类号： G01B9/02 , G01J3/00 , G01J3/45 , G02B17/00 , G02B21/00
摘要： In one embodiment, a flow cytometer is disclosed having a compact light detection module. The compact light detection module includes an image array with a transparent block, a plurality of micro-mirrors in a row coupled to a first side of the transparent block, and a plurality of filters in a row coupled to a second side of the transparent block opposite the first side. Each of the plurality of filters reflects light to one of the plurality of micro-mirrors and passes light of a differing wavelength range and each of the plurality of micro-mirrors reflects light to one of the plurality of filters, such that incident light into the image array zigzags back and forth between consecutive filters of the plurality of filters and consecutive micro-mirrors of the plurality of micro-mirrors. A radius of curvature of each of the plurality of micro-mirrors images the fiber aperture onto the odd filters and collimates the light beam on the even filters.
摘要翻译：在一个实施例中，公开了一种具有紧凑型光检测模块的流式细胞仪。紧凑型光检测模块包括具有透明块的图像阵列，耦合到透明块的第一侧的行中的多个微镜以及耦合到透明块的第二侧的行中的多个滤波器在第一面对面。多个滤光器中的每个滤光器将光反射到多个微镜中的一个并且传递不同波长范围的光，并且多个微镜中的每一个将光反射到多个滤光器中的一个，使得入射到图像阵列在所述多个滤波器的连续滤波器与所述多个微镜的连续微镜之间来回锯齿形。多个微镜中的每一个的曲率半径将光纤孔径成像到奇数滤波器上并且将光束准直到偶数滤波器上。

2. 发明申请

WO2017189783A1 COMPACT MULTI-COLOR FLOW CYTOMETER 审中-公开
标题翻译：紧凑的多色流式细胞仪
公开(公告)号：WO2017189783A1
公开(公告)日：2017-11-02
申请号：PCT/US2017/029724
申请日：2017-04-26
申请人： CYTEK BIOSCIENCES, INC.
发明人： YAN, Ming , CHASE, Eric , VRANE, David , JIANG, Wenbin
IPC分类号： G06F19/00 , G01N15/14 , G01N21/00 , G01N21/76 , G01N21/77
摘要： A system, an apparatus, and a method are provided for a modular flow cytometer with a compact size. In one embodiment, the modular flow cytometry system includes the following: a laser system for emitting laser beams; a flow cell assembly positioned to receive the laser beams at an interrogation region of a fluidics stream where fluoresced cells scatter the laser beams into fluorescent light; a fiber assembly positioned to collect the fluorescent light; and a grating system including a dispersive element and a receiver assembly, wherein the dispersive element is positioned to receive the fluorescent light from the fiber assembly and to direct spectrally dispersed light toward the receiver assembly.
摘要翻译：为具有紧凑尺寸的模块化流式细胞仪提供系统，装置和方法。在一个实施例中，模块化流式细胞术系统包括以下部分：用于发射激光束的激光系统; 流动池组件，所述流动池组件定位成在流体流的询问区域处接收激光束，其中荧光细胞将激光束散射到荧光灯中; 定位成收集荧光的纤维组件; 以及包括色散元件和接收器组件的光栅系统，其中色散元件被定位成接收来自光纤组件的荧光并将光谱分散的光导向接收器组件。

3. 发明申请

WO2017185071A1 FLOW CYTOMETRY WITH DUAL LASER BEAMS 审中-公开
标题翻译：双激光束流动细胞计数
公开(公告)号：WO2017185071A1
公开(公告)日：2017-10-26
申请号：PCT/US2017/029009
申请日：2017-04-21
申请人： CYTEK BIOSCIENCES, INC.
发明人： YAN, Ming , CHASE, Eric , HSIEH, Yung-Chieh
IPC分类号： G01N15/14 , G01J4/00 , G01N15/02 , G01N15/06 , G02B27/09
摘要： A system, method, and apparatus are provided for cytometry with dual laser beams. In one example, the method includes directing an incident light beam from a source to enter an optical waveplate; polarizing the incident light beam into a polarized light beam in response to the incident light beam entering through the optical waveplate; directing the polarized light beam to enter a birefringent crystal; separating the polarized light beam into an ordinary light beam and an extraordinary light beam in response to the polarized light beam entering the birefringent crystal; directing the ordinary light beam and the extraordinary light beam to enter a lens; focusing the ordinary light beam and the extraordinary light beam into dual light beams separated by a beam displacement; and coupling the dual light beams to form a sample region having substantially uniform light intensity to analyze moving particles in the particle analyzer.
摘要翻译：提供了用于双激光束的细胞术的系统，方法和设备。在一个示例中，该方法包括引导来自光源的入射光束进入光学波片; 响应于通过光学波片进入的入射光束将入射光束偏振成偏振光束; 引导偏振光束进入双折射晶体; 响应于进入双折射晶体的偏振光束将偏振光束分成普通光束和异常光束; 引导普通光束和异常光束进入透镜; 将普通光束和异常光束聚焦成由光束位移分开的双光束; 并耦合双光束以形成具有基本均匀光强度的样品区域，以分析颗粒分析仪中的移动颗粒。

4. 发明申请

WO2023000166A1 Exhaust after-treatment system, operating method thereof and computer program product 审中-公开
公开(公告)号：WO2023000166A1
公开(公告)日：2023-01-26
申请号：PCT/CN2021/107331
申请日：2021-07-20
申请人： ROBERT BOSCH GMBH , YAN, Ming
发明人： YAN, Ming
IPC分类号： F01N3/20 , F01N9/00
摘要： The invention provides an exhaust after-treatment system (2) for a diesel engine (1), comprising an injection device (21) for injecting exhaust gas treatment agent and a controller (23) for controlling the injection device (21), wherein the controller (23) is provided to select different strategies for determining an injection limit value of the exhaust gas treatment agent depending on whether the diesel engine (1) has a demand for revolution increase within a predetermined period of time, and to keep an injection amount of the injection device (21) below the injection limit value. The invention also provides a method for operating the exhaust after-treatment system (2) and a corresponding computer program product. With the invention, different strategies can be selected for determining the injection limit value of the exhaust gas treatment agent depending on whether the diesel engine has the demand for revolution increase within the predetermined period of time, so that over-injection of the exhaust gas treatment agent can be reduced and, in particular, crystallization of the exhaust gas treatment agent can be avoided.

5. 发明申请

WO2010130240A1 MAGNETOELEKTRONISCHE BAUELEMENTE UND MESSVERFAHREN 审中-公开
标题翻译：磁电子元件及测量方法
公开(公告)号：WO2010130240A1
公开(公告)日：2010-11-18
申请号：PCT/DE2010/000495
申请日：2010-05-03
申请人： FORSCHUNGSZENTRUM JÜLICH GMBH , HERTEL, Riccardo , YAN, Ming
发明人： HERTEL, Riccardo , YAN, Ming
IPC分类号： H01L43/00 , G11C11/16
CPC分类号： H01L43/00 , G01R33/1292 , G11C11/161 , G11C11/1675 , G11C11/1693 , G11C19/0808 , G11C19/0841 , G11C2207/00 , H01L21/00 , H01L2221/00
摘要： Die erfindungsgemäßen magnetoelektronischen Bauelemente umfassen mindestens eine längliche Arbeitsstruktur aus einem ferromagnetischen Material, entlang der magnetische Domänenwände wandern können, Mittel zur Beaufschlagung dieser Arbeitsstruktur mit einem elektrischen Strom sowie mindestens einen Magnetfeldsensor für das von der Arbeitsstruktur ausgehende Magnetfeld. Erfindungsgemäß ist die Arbeitsstruktur derart ausgestaltet, dass sie Domänenwände, deren transversale Magnetisierungsrichtung in ihrer Mitte keine Vorzugsrichtung in der Ebene senkrecht zu ihrer Wanderungsrichtung entlang der Arbeitsstruktur aufweist, und/oder masselose Domänenwände auszubilden vermag. Es wurde erkannt, dass die kinetische Energie derartiger bewegter Domänenwände verschwindet. Sie unterliegen daher weder dem Walker-Limit noch dem intrinsischen Pinning. Dadurch können die Bauelemente Informationen schneller einlesen, speichern oder verarbeiten und schließlich ausgeben. Die Erfindung bezieht sich auch auf ein Verfahren zur Messung des nicht-adiabatischen Spintransferparameters ß eines ferromagnetischen Materials. Dieses Verfahren wurde im Zuge einer genaueren Untersuchung der erkannten Phänomene entwickelt.
摘要翻译：根据本发明的磁 - 电子部件包括一铁磁材料可沿磁畴壁迁移中的至少一种长椭圆形的工作结构的装置，用于以电流和用于从工作结构磁场发出的光的至少一个磁场传感器应用这种工作结构。根据本发明的工作结构被设计为使得其能够形成具有在中心它们的横向磁化方向的平面内没有优选的方向垂直于沿着所述工作结构其行进方向的畴壁，和/或无质量的畴壁。人们认识到，这样的移动畴壁的动能消失。因此，他们不受沃克极限也不是内在的牵制。因此，该设备可以读取信息更快，存储或处理和最终消费。本发明还涉及一种用于测量一个铁磁材料的非绝热自旋转移参数SS的方法。这种方法被开发为一体的检测现象进行详细检查的一部分。

6. 发明申请

WO2010052609A2 COIL ARRANGEMENT AND MAGNETIC INDUCTION TOMOGRAPHY SYSTEM COMPRISING SUCH A COIL ARRANGEMENT 审中-公开
标题翻译：包括这种线圈布置的线圈布置和磁感应感应系统
公开(公告)号：WO2010052609A2
公开(公告)日：2010-05-14
申请号：PCT/IB2009/054766
申请日：2009-10-28
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , CHEN, Dayu , YAN, Ming , JIN, Hua
发明人： CHEN, Dayu , YAN, Ming , JIN, Hua
IPC分类号： G01V3/10
CPC分类号： G01V3/104
摘要： The invention relates to a coil arrangement comprising at least one transmitting coil for generating a primary magnetic field; and a plurality of measurement coils; wherein the at least one transmitting coil (408, 409) and the plurality of measurement coils (410, 411) are arranged in such a way that the flux curve of the primary magnetic field generated by a transmitting coil (409) among said at least one transmitting coil (408, 409) passes into and out of a first measurement coil (410) among said plurality of measurement coils (410, 411), the first measurement coil being the coil closest to the transmitting coil. By enabling the flux of the primary magnetic field to pass into and out of a first measurement coil, the signal induced on the first measurement coil by the positive and negative flux can be compensated, resulting in a reduction of the signal strength of the induced signal on the measurement coil and the signal dynamic range.
摘要翻译：本发明涉及一种线圈装置，其包括至少一个用于产生初级磁场的传输线圈; 和多个测量线圈; 其中所述至少一个发射线圈（408,409）和所述多个测量线圈（410,411）以这样的方式布置，使得由所述至少一个发射线圈（409）产生的所述初级磁场的磁通曲线一个发射线圈（408,409）在所述多个测量线圈（410,411）之间进入和离开第一测量线圈（410），第一测量线圈是最靠近发射线圈的线圈。通过使一次磁场的磁通量能够通过和流出第一测量线圈，可以补偿在第一测量线圈上由正和负磁通感应的信号，导致感应信号的信号强度的降低在测量线圈和信号动态范围内。

7. 发明申请

WO2007075175A1 THERMAL CONTROL OF OPTICAL COMPONENTS 审中-公开
标题翻译：光学元件的热控制
公开(公告)号：WO2007075175A1
公开(公告)日：2007-07-05
申请号：PCT/US2005/047513
申请日：2005-12-29
申请人： NEOPHOTONICS CORPORATION , YAN, Ming , TICKNOR, Anthony, J. , HO, Calvin , XU, Hao , WEAVER, Jason , TARTER, Thomas, S. , LAM, Jane
发明人： YAN, Ming , TICKNOR, Anthony, J. , HO, Calvin , XU, Hao , WEAVER, Jason , TARTER, Thomas, S. , LAM, Jane
IPC分类号： G02B6/12 , G02B6/26 , G02B6/28 , G02B6/34 , G02B6/42
CPC分类号： G02B6/12026 , G02B6/12011 , G02B2006/12135
摘要： A linearized thermal and optical model of an optical integrated circuit can be used to temperature-stabilize one or more optical elements of the circuit (455) using active temperature regulation. To stabilize a single optical element, such as an arrayed waveguide grating (AWG), a temperature sensor (425) and a heater (427) can be provided proximate to the grating. Thermal and optical coefficients can be then used to select an appropriate temperature set-point for the temperature controller (400) that receives readings from the sensor and determines the power dissipated in the heater. Multiple AWG's can be stabilized individually, lumping cross- heating factors together with other environmental factors.
摘要翻译：可以使用光学集成电路的线性化热和光学模型来使用主动温度调节来温度稳定电路（455）的一个或多个光学元件。为了稳定诸如阵列波导光栅（AWG）的单个光学元件，可以在光栅附近提供温度传感器（425）和加热器（427）。然后可以使用热和光系数来为接收来自传感器的读数的温度控制器（400）选择适当的温度设定点，并确定加热器中消耗的功率。多个AWG可以单独稳定，将交叉加热因素与其他环境因素结合。

8. 发明申请

WO2013006762A2 MULTIPLE-ENZYME NANOCOMPLEXES 审中-公开
标题翻译：多元酶纳米复合物
公开(公告)号：WO2013006762A2
公开(公告)日：2013-01-10
申请号：PCT/US2012/045690
申请日：2012-07-06
申请人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA , LU, Yunfeng , YAN, Ming , LIU, Yang
发明人： LU, Yunfeng , YAN, Ming , LIU, Yang
CPC分类号： A61K38/443 , A61K38/44 , A61K47/549 , A61K47/64 , B82Y5/00 , C12N11/18
摘要： Provided are nanocomplexes having at least two different enzymes and a polymeric network anchored to at least one of the enzymes. In some embodiments, the activities of the enzymes catalyze a cascade reaction.
摘要翻译：提供了具有至少两种不同酶的纳米复合物和锚定至至少一种酶的聚合物网络。在一些实施方案中，酶的活性催化级联反应。

9. 发明申请

WO2011018744A1 METHOD AND DEVICE FOR MEASURING CONDUCTIVITY OF AN OBJECT 审中-公开
标题翻译：用于测量物体电导率的方法和装置
公开(公告)号：WO2011018744A1
公开(公告)日：2011-02-17
申请号：PCT/IB2010/053581
申请日：2010-08-09
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , YAN, Ming , CHEN, Dayu , LI, Hui , JIN, Hua
发明人： YAN, Ming , CHEN, Dayu , LI, Hui , JIN, Hua
IPC分类号： A61B5/053
CPC分类号： A61B5/0536 , A61B5/0522
摘要： The invention provides a device (10) for measuring the conductivity of an object (20), and the device (10) comprises: a measuring unit (11) for measuring a first voltage when the object (20) is not placed in the measuring unit (11), for measuring the voltage of the object (20) when the object (20) is placed in the measuring unit (11) after measuring the first voltage, and for measuring a second voltage when the object (20) is moved away from the measuring unit (11) after measuring the voltage of the object (20); a calculating unit (12) for calculating the difference between the first voltage and the second voltage; and an adjusting unit (13) for adjusting the voltage of the object (20), based on said difference, to generate an adjusted voltage of the object (20).
摘要翻译：本发明提供了一种用于测量物体（20）的导电性的装置（10），并且装置（10）包括：测量单元（11），用于当物体（20）未被放置在测量中时测量第一电压单元（11），用于在物体（20）在测量第一电压之后放置在测量单元（11）中时测量物体（20）的电压，并且当物体（20）移动时测量第二电压在测量对象（20）的电压之后离开测量单元（11）; 计算单元（12），用于计算第一电压和第二电压之间的差; 以及调整单元（13），用于基于所述差值调节所述物体（20）的电压，以产生所述物体（20）的调节电压。

10. 发明申请

WO2010103461A1 METHOD AND APPARATUS FOR MEASURING AN OBJECT OF INTEREST 审中-公开
标题翻译：用于测量兴趣对象的方法和装置
公开(公告)号：WO2010103461A1
公开(公告)日：2010-09-16
申请号：PCT/IB2010/051019
申请日：2010-03-10
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , YAN, Hua , YAN, Ming , LIU, Hui
发明人： YAN, Hua , YAN, Ming , LIU, Hui
IPC分类号： A61B5/053
CPC分类号： A61B5/0536 , A61B5/0522 , G01V3/104
摘要： This invention relates to a method of, and apparatus for, measuring an object of interest. The apparatus (100) comprises an outer layer (102), an inner layer (101) which is intended to be attached to the object of interest, a coil arrangement comprising at least one transmitting coil (111) and at least one measurement coil (111') arranged on the inner layer (101) obtains measurement signals, exciting circuits (112) and processing circuits (112') are configured to cooperate with the coils (111, 111') to get the measurement result. The inner layer (101) is movable together with the object of interest. At least part of the exciting circuits (112) and the processing circuits (112') are arranged on the outer layer (102). In this way, the measurement error caused by movement of the object of interest can be avoided and the object of interest can feel comfortable by being mobile.
摘要翻译：本发明涉及测量感兴趣对象的方法和装置。设备（100）包括外层（102），旨在附着到感兴趣物体的内层（101），包括至少一个传输线圈（111）和至少一个测量线圈（ 111'）设置在内层（101）上，获得测量信号，激励电路（112）和处理电路（112'）被配置为与线圈（111,111'）配合以获得测量结果。内层（101）可与感兴趣的物体一起移动。励磁电路（112）和处理电路（112'）的至少一部分布置在外层（102）上。以这种方式，可以避免由感兴趣的对象的移动引起的测量误差，并且感兴趣的对象可以通过移动来感觉舒适。

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