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1. 发明申请

WO2008139473A3 DELIVERY DEVICE FOR DELIVERING BIOACTIVE AGENTS TO INTERNAL TISSUE IN A BODY 审中-公开
标题翻译：用于向身体内部组织递送生物剂的递送装置
公开(公告)号：WO2008139473A3
公开(公告)日：2010-02-18
申请号：PCT/IL2008000662
申请日：2008-05-13
申请人： BIOPROTECT LTD , SHOHAT SHAUL , MACHLEV ELI , HAIMOVICH DANA , DOMB ABRAHAM JACKOB
发明人： SHOHAT SHAUL , MACHLEV ELI , HAIMOVICH DANA , DOMB ABRAHAM JACKOB
IPC分类号： A61F2/958 , A61M31/00
CPC分类号： A61M25/10 , A61L29/146 , A61L29/148 , A61L29/16 , A61L2300/232 , A61L2300/25 , A61L2300/252 , A61L2300/258 , A61L2300/30 , A61L2300/604 , A61M25/1029 , A61M2025/0056 , A61M2025/0681 , A61M2025/105 , A61M2025/1054 , A61M2025/1088
摘要： A device and method for administering a bioactive agent to internal tissue in a body, by introducing a balloon in a deflated condition into the body, inflating the balloon, introducing the bioactive agent into the balloon at the time of, after, or before the inflation of the balloon, and delivering the bioactive agent from the balloon to the tissue.
摘要翻译：一种将生物活性剂施用于身体内部组织的装置和方法，通过将处于放气状态的气囊引入体内，使气囊膨胀，在膨胀之前，之后或之前将生物活性剂引入气囊中并将生物活性剂从气囊输送到组织。

2. 发明申请

WO2008111078A2 SOFT TISSUE FIXATION DEVICES 审中-公开
标题翻译：软组织固定装置
公开(公告)号：WO2008111078A2
公开(公告)日：2008-09-18
申请号：PCT/IL2008000354
申请日：2008-03-13
申请人： BIOPROTECT LTD , SHOHAT SHAUL
发明人： SHOHAT SHAUL
IPC分类号： A61B17/04
CPC分类号： A61B17/00234 , A61B17/0057 , A61B2017/00004 , A61B2017/00557 , A61B2017/00792 , A61B2017/00796 , A61B2017/22061 , A61F2/0045 , A61F2/0063 , A61F2002/0072 , A61F2210/0004
摘要： Remodeling of body tissue using a bioabsorbable implant that maintains or otherwise mechanically assists a more permanent implant or other treatment take, for example, by the treatment causing fibrosis. For example, the apparatus and methods can be used for hernia, organ prolapse and cosmetic purposes, such as breast and face lifts.
摘要翻译：使用维持或以其他方式机械辅助更持久的植入物或其它治疗的生物可吸收植入物重建身体组织，例如通过引起纤维化的治疗。例如，该装置和方法可用于疝气，器官脱垂和化妆用途，例如乳房和面部电梯。

3. 发明申请

WO2011083474A2 CONTROLLED TISSUE DISSECTION SYSTEMS AND METHODS 审中-公开
标题翻译：控制组织分离系统和方法
公开(公告)号：WO2011083474A2
公开(公告)日：2011-07-14
申请号：PCT/IL2011000018
申请日：2011-01-06
申请人： BIOPROTECT LTD , SHOHAT SHAUL
发明人： SHOHAT SHAUL
IPC分类号： A61B17/02
CPC分类号： A61B8/12 , A61B8/445 , A61B17/320016 , A61B2017/320048 , A61B2034/107
摘要： A tissue dissecting device, including an inflatable bladder configured to be inserted into a body via an introducer tube in a compact deflated state, and to be inflated to a substantially planar form in a manner which dissects tissue. A method for dissecting tissue, including inserting an inflatable bladder, in a deflated state, via an introducer tube, into a space in a body, and inflating the bladder to a substantially planar form, thereby dissecting tissue. A method for dissecting tissue, including inserting an introducer tube via an incision into a body, inserting an inflatable bladder, in a deflated state, via the introducer tube, into a space in the body, pulling the introducer tube back at least a length of the deflated bladder, inflating the bladder, via a filling tube, to a substantially planar form, thereby dissecting tissue, disconnecting the filling tube from the bladder, retracting the filling tube and the introducer tube from the body. Related apparatus and methods are also described.
摘要翻译：一种组织解剖装置，包括可膨胀囊，其构造成以紧凑的放气状态通过导引管插入体内，并且以解剖组织的方式充气至基本上平面的形式。一种用于解剖组织的方法，包括将处于放气状态的可膨胀气囊经由导引管插入体内的空间，并将膀胱充气至基本平面的形式，从而解剖组织。一种用于解剖组织的方法，包括通过切口将导引管插入到体内，将处于放气状态的可膨胀囊经由导引管插入到体内的空间中，将引导管拉回至少一段长度放气的膀胱，通过填充管将膀胱充气到基本上平面的形式，从而解剖组织，将填充管从囊中分离，使填充管和导引管从身体缩回。还描述了相关装置和方法。

4. 发明申请

WO2008001381A3 GASTROINTESTINAL PROSTHESES 审中-公开
公开(公告)号：WO2008001381A3
公开(公告)日：2009-04-30
申请号：PCT/IL2007000799
申请日：2007-06-28
申请人： SLIMEDICS LTD , SHOHAT SHAUL , BAR-ON RAZ
发明人： SHOHAT SHAUL , BAR-ON RAZ
IPC分类号： A61M29/00 , A61F2/04
CPC分类号： A61F2/04 , A61F5/0079
摘要： Gastrointestinal prosthesis for restraining the rate of the gastric digestion consists of a compressible proximal member connected by a string to a distal member, to be introduced into the intestine. The proximal member has an internal space, which is opened to the gastric lumen and may include passageways for the gastric content as well as open grooves or niches disposed on its external wall. The volume of a proximal member compressed by the gastric wall cannot get smaller than a lower threshold. Anchoring the gastrointestinal prosthesis at its desired location is accomplished by means of the proximal member the geometrical shape of which conforms the geometrical shape of a portion of the gastric lumen; as well as by means of the geometrical shape of the distal member which conforms the geometrical shape of a segment of the duodenum and/or a segment of the intestine.
摘要翻译：用于抑制胃消化速率的胃肠假体由通过弦连接到远端构件的可压缩近端构件组成，以被引入肠中。近端构件具有向胃腔敞开的内部空间，并且可以包括用于胃内容物的通道以及设置在其外壁上的开放凹槽或壁龛。由胃壁压缩的近端构件的体积不能小于较低的阈值。通过其几何形状符合胃腔的一部分的几何形状的近端构件来实现在其期望位置锚定胃肠假体。以及通过符合十二指肠的一部分和/或肠段的几何形状的远端构件的几何形状。

5. 发明申请

WO2007080578A3 SYSTEM AND METHOD FOR THERMALLY TREATING TISSUES 审中-公开
标题翻译：用于热处理组织的系统和方法
公开(公告)号：WO2007080578A3
公开(公告)日：2009-04-16
申请号：PCT/IL2007000029
申请日：2007-01-09
申请人： BIOSPIRAL LTD , SHOHAT SHAUL , SHABAT RONI , SEGAL ELAZAR , PAZ ADRIAN
发明人： SHOHAT SHAUL , SHABAT RONI , SEGAL ELAZAR , PAZ ADRIAN
IPC分类号： A61B18/04
CPC分类号： A61B18/04 , A61B2017/00274 , A61B2018/00547 , A61B2018/046
摘要： A system and method are provided for thermally treating tissues in percutaneous surgery or endoluminal treatments. The system consists of at least one catheter for thermally treating a tissue, hydraulic unit for circulating fluids through the catheters and a control station by which an operator is displayed with, and inputs and/or modifies, working parameters of the system. The catheters have an operational face, which is optionally expandable and encloses a lumen through which the fluids are circulated. The method disclosed implements cooling of the targeted tissue prior to its heating. For heating and or cooling the tissues, the operational face of a catheter is pressed against a surface of the targeted tissue while heat emitted from or conducted to the tissue is respectively transferred into or from the circulated fluids.
摘要翻译：提供用于经皮手术或腔内治疗中热处理组织的系统和方法。该系统包括用于热处理组织的至少一个导管，用于使流体通过导管循环的液压单元和操作者通过该控制站显示并输入和/或修改系统的工作参数。导管具有可操作的面，其可任选地可膨胀并且包围流体通过其流通的内腔。所公开的方法在加热之前对目标组织进行冷却。为了加热和/或冷却组织，将导管的操作面压在目标组织的表面上，同时从组织发出或传导到组织的热量分别转移到循环流体中或从循环流体转移。

6. 发明申请

WO2011007358A2 CIRCUMCISION DEVICE AND METHOD FOR MASS CIRCUMCISION 审中-公开
标题翻译：电路设备和大容量电路的方法
公开(公告)号：WO2011007358A2
公开(公告)日：2011-01-20
申请号：PCT/IL2010000568
申请日：2010-07-15
申请人： CIRC MEDTECH LTD , FUERST OREN , KILEMNICK IDO , SHOHAT SHAUL
发明人： FUERST OREN , KILEMNICK IDO , SHOHAT SHAUL
IPC分类号： A61B17/326 , A61H19/00 , A61M31/00
CPC分类号： A61B17/326 , A61B17/12009 , A61B17/1322 , A61B90/96 , A61B90/98 , A61B2017/0073 , A61B2017/00867 , A61B2017/12018 , A61B2090/061 , A61H19/32 , A61H23/02 , A61H39/002 , A61M35/00
摘要： System for effecting ischemic necrosis in a foreskin of a penis, including a rigid ring, at least one elastic ring and at least one circumferential groove, the rigid ring including an inner surface, the inner surface including an inner diameter, and an outer surface, the outer surface including an outer diameter, the elastic ring being configured to substantially fit around a surface of the rigid ring, the circumferential groove being located on a surface of at least one of the rigid ring and the elastic ring, wherein the inner diameter of the rigid ring is at least slightly larger than a diameter of a shaft of the penis, wherein a diameter of the elastic ring in a relaxed state is at least substantially equal to the diameter of the shaft of the penis, wherein the rigid ring is placed around a first surface of the foreskin, wherein the elastic ring is placed around a second surface of the foreskin, the foreskin being placed within the circumferential groove, the rigid ring and the elastic ring thereby compressing the foreskin in the circumferential groove with a compression force, and wherein the compression force is sufficient to effect ischemic necrosis in the foreskin.
摘要翻译：用于在阴茎包皮中实现缺血性坏死的系统，包括刚性环，至少一个弹性环和至少一个周向凹槽，刚性环包括内表面，内表面包括内径和外表面，所述外表面包括外径，所述弹性环被配置为基本上装配在所述刚性环的表面周围，所述周向槽位于所述刚性环和所述弹性环中的至少一个的表面上，其中，刚性环至少稍微大于阴茎轴的直径，其中处于松弛状态的弹性环的直径至少基本上等于阴茎轴的直径，其中刚性环被放置围绕包皮的第一表面，其中所述弹性环围绕包皮的第二表面放置，所述包皮放置在周向凹槽内，刚性环和睫毛由此以压缩力压缩周向槽中的包皮，并且其中压缩力足以实现包皮中的缺血性坏死。

7. 发明申请

WO2012077109A3 A SUPPORT ELEMENT FOR CIRCUMCISION AND SYSTEM COMPRISING THE SAME 审中-公开
标题翻译：包括其中的电路和系统的支持单元
公开(公告)号：WO2012077109A3
公开(公告)日：2012-08-02
申请号：PCT/IL2011050040
申请日：2011-12-05
申请人： CIRC MEDTECH LTD , FUERST OREN , KILEMNICK IDO , SHOHAT SHAUL
发明人： FUERST OREN , KILEMNICK IDO , SHOHAT SHAUL
IPC分类号： A61B17/326
CPC分类号： A61B17/326 , A61B90/06 , A61B2090/061
摘要： The present disclosure provides a support element (10,110) for use in effecting ischemic necrosis in a foreskin (186) of a penis, being a closed- loop member defining an opening (12) dimensioned to permit a penis glans to pass therethrough and having an inner surface (14) and an outer surface (16); the outer surface comprising a circumferential support (18, 118) for an elastic ring (150) to be mounted thereon, said circumferential support being formed within a groove (20,120) in at least part of the outer surface; at least one first segment (26, 28) of the outer surface having an outer curvature of a radius larger than that of its flanking second segments (30, 32). Also provided herein is a system (100) for effecting ischemic necrosis in a foreskin (186) of a penis, comprising the support element (110) and elastic ring (150), and optionally a deployment element (160) for mounting the elastic ring over the foreskin and support element.
摘要翻译：本公开提供了一种用于实现阴茎包皮（186）中的缺血性坏死的支撑元件（10,110），其是限定开口（12）的闭环构件，所述闭合构件的尺寸被设计成允许阴茎龟头穿过其中并具有内表面（14）和外表面（16）; 所述外表面包括用于安装在其上的弹性环（150）的周向支撑件（18,118），所述周向支撑件形成在所述外表面的至少一部分中的凹槽（20,120）内; 所述外表面的至少一个第一段（26,28）具有比其侧翼第二段（30,32）的半径大的半径的外曲率。本文还提供了一种用于在阴茎包皮（186）中实现缺血性坏死的系统（100），其包括所述支撑元件（110）和弹性环（150），以及任选的用于安装所述弹性环的展开元件（160）超过包皮和支撑元素。

8. 发明申请

WO2010097724A9 EXPANDABLE JOINT IMPLANT 审中-公开
标题翻译：可扩展接合植入
公开(公告)号：WO2010097724A9
公开(公告)日：2011-07-28
申请号：PCT/IB2010050562
申请日：2010-02-08
申请人： ORTHO SPACE LTD , SHOHAT SHAUL
发明人： SHOHAT SHAUL
IPC分类号： A61F2/42
CPC分类号： A61F2/4241 , A61F2/4225 , A61F2/4261 , A61F2002/0086 , A61F2002/30062 , A61F2002/30171 , A61F2002/302 , A61F2002/30224 , A61F2002/30242 , A61F2002/30252 , A61F2002/30261 , A61F2002/30273 , A61F2002/3028 , A61F2002/30576 , A61F2002/30581 , A61F2002/30909 , A61F2002/3093 , A61F2002/30932 , A61F2002/4258 , A61F2210/0004 , A61F2230/005 , A61F2230/0063 , A61F2230/0065 , A61F2230/0069 , A61F2230/0071 , A61F2230/0073 , A61F2230/0082 , A61F2230/0086 , A61F2310/0097
摘要： A soft, expandable, implantable device sized for spacing between small bones comprising a first smooth surface on which a first small bone may slide. Implant (700) includes an opening (704) (passage) extending through the device for promoting fibrotic development through the opening from a direction from both thumb metacarpal (202) and trapezium (204). Passage (704) is optionally distally positioned from a one-way inflation valve (706) included inside an inflation port (702) substantially limiting possible damage to the device due to the insertion pressure of an expansion fluid. An inflation cannula and/or needle may be attached to inflation port (702) and inflation valve (706) for introducing the expansion fluid into the device. Implant (700) is inserted in a deflated mode and is positioned so that thumb metacarpal (202) abuts distal side (703) of the device when expanded and trapezium (704) abuts proximal side (701). Both distal side (703) and proximal side (701) include a smooth surface for allowing relative movement of thumb metacarpal (202) and trapezium (204) with respect to device (700).
摘要翻译：一种柔软的，可扩张的，可植入的装置，其尺寸适于在小骨之间的间隔，其包括第一平滑表面，第一小骨可以在其上滑动。植入物（700）包括延伸穿过该装置的开口（704），用于促进从拇指掌骨（202）和梯形（204）的方向穿过开口的纤维化发育。通道（704）可选地远离包括在充气端口（702）内的单向充气阀（706）定位，从而基本上限制了由于膨胀流体的插入压力而对装置的可能损坏。充气插管和/或针可以附接到充气端口（702）和充气阀（706），用于将膨胀流体引入到装置中。植入物（700）以放气模式插入并且定位成使得当扩张和梯形（704）邻近近侧（701）时，拇指掌骨（202）邻近装置的远侧（703）。远端侧（703）和近侧（701）均包括平滑表面，用于允许拇指掌骨（202）和梯形物（204）相对于装置（700）相对运动。

9. 发明申请

WO2008111073A3 PROSTHETIC DEVICES AND METHODS FOR USING SAME 审中-公开
标题翻译：前置装置及其使用方法
公开(公告)号：WO2008111073A3
公开(公告)日：2010-02-18
申请号：PCT/IL2008000347
申请日：2008-03-13
申请人： ORTHO SPACE LTD , SHOHAT SHAUL
发明人： SHOHAT SHAUL
IPC分类号： A61F2/02
CPC分类号： A61F2/40 , A61B17/562 , A61B17/7061 , A61B17/7097 , A61B17/7275 , A61B17/8805 , A61B17/8855 , A61B2017/00557 , A61F2250/0003
摘要： A prosthesis for reducing injury to soft tissues of the body, comprising an implantable member adapted to simulate at least one of a size or a shape of a naturally occurring bursa, where the member may be inflatable or otherwise expandable, flexible or rigid, and may be composed of a biocompatible, biodegradable, or non-biodegradable material The member is adapted to be implanted at a musculoskeletal attachment site or at a site between a muscle and a bone, and is shaped and sized to reduce injury to the site The prosthesis may also include a plug which seals the prosthesis automatically upon removal of an inflation tube.
摘要翻译：一种用于减少身体软组织损伤的假体，包括适于模拟天然存在的囊的尺寸或形状中的至少一种的可植入构件，其中所述构件可以是充气的或可膨胀的，柔性的或刚性的，并且可以由生物相容性，可生物降解的或不可生物降解的材料组成。该构件适于植入肌肉骨骼附着部位或肌肉和骨骼之间的部位，并且其形状和尺寸以减少对部位的损伤。假体可以还包括塞子，其在去除充气管时自动密封假体。

10. 发明申请

WO2008035329A3 GASTROINTESTINAL CAPSULE 审中-公开
标题翻译：胃肠胶囊
公开(公告)号：WO2008035329A3
公开(公告)日：2009-05-07
申请号：PCT/IL2007001139
申请日：2007-09-17
申请人： VIBRANT LTD , SHOHAT SHAUL , BELENKY ALEXANDER , SHABAT RONI
发明人： SHOHAT SHAUL , BELENKY ALEXANDER , SHABAT RONI
IPC分类号： A61H1/00 , A61H23/02
CPC分类号： A61H23/0263 , A61H23/02 , A61H2205/083
摘要： An ingestible gastrointestinal capsule (GIC) for mechanically stimulating a segment of the gastrointestinal (Gl) wall by alternately and repeatedly pressurizing, and/or vibrating it is provided. The GIC is programmed to being activated following a predefined time delay. The activated GIC agitates, shakes, rattles, jolts, vibrates and/or moves in a reciprocal expanding and contracting motion thereby mechanically stimulating the adjacent segment of the Gl wall at a targeted location. Activation of the GIC may include a number of automatically accomplished partial activations, such as when the time elapsed from the moment of setting the GIC on equals a predefined time delay; when the mechanical load applied onto the GIC exceeds, and/or gets lower than a respective predefined level of mechanical load; when the ambient pH reaches a predefined level, or changes, and/or a temperature associated with the user reaches a predefined threshold. Agitation is accomplished by means of agitation means embedded in the GIC. Such agitation means includes an unbalanced weight attached to the shaft of an electric motor, an actuator implemented by, such as an electric solenoid, an electro-active polymer (EAP), a dielectric elastomer actuator (DEA), embedded in a GIC of the invention.
摘要翻译：提供了用于通过交替地和反复地加压和/或振动来机械刺激胃肠（G1）壁的一部分的可摄入胃肠胶囊（GIC）。 GIC被编程为在预定义的时间延迟之后被激活。激活的GIC搅动，摇动，摇晃，颠簸，振动和/或以往复的伸缩运动移动，从而在目标位置机械地刺激G1壁的相邻部分。 GIC的激活可以包括许多自动完成的部分激活，例如当从设置GIC开始的时刻经过等于预定时间延迟的时间时; 当施加到GIC上的机械载荷超过和/或变得低于相应的预定水平的机械载荷时; 当环境pH达到预定义的水平或变化时，和/或与用户相关联的温度达到预定阈值。搅拌是通过嵌入GIC中的搅拌装置来实现的。这种搅拌装置包括附接到电动机的轴的不平衡重物，由例如电磁螺线管执行的致动器，嵌入在GIC中的电活性聚合物（EAP），介电弹性体致动器（DEA）发明。

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