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    • 10. 发明申请
    • DIRECTIONAL ENERGY EMITTING IMPLANT
    • 方向能量发射植被
    • WO0240092A3
    • 2003-02-13
    • PCT/US0145689
    • 2001-11-14
    • APPLE MARC GAPPLE MELVIN J
    • APPLE MARC GAPPLE MELVIN J
    • A61B17/68A61B17/80A61F2/00A61F2/30A61F2/32A61F2/38A61K51/12A61N5/10A61F2/02
    • A61B17/68A61B17/8066A61F2/32A61F2/38A61F2002/30082A61F2002/30299A61F2002/30878A61F2002/30932A61F2210/0095A61F2230/0093A61K51/1282A61N5/1001A61N2005/1019
    • The insert device (15) is for attachment either to natural tissue or a prosthetic device, and delivers a prescribed dosage of energy to targeted tissue. The insert device (15) includes an energy-source material within the insert device (15) that delivers the prescribed dosage of energy to the targeted tissue, while minimizing exposure of nontargeted tissue. The targeted tissue has a known radio-response profile and is adjacent to the targeted tissue. The energy-source material in combination with the prosthetic device defines an actual energy-delivery distribution field. The energy-delivery distribution field has a configuration similar to the known profile of the targeted tissue. The prescribed dosage of energy is applied from energy-source material within the insert device (15) and directed to the targeted tissue. The prescribed energy dosage is determined by using known physics characteristics of the energy-source material, and by the placement of the energy-source material relative to the targeted tissue. The implant system reduces any occurrence of heterotopic ossification caused by the implant, inhibits growth or migration of benign or malignant living cells, and minimizes or even eliminates infectious processes or delayed keloid or scar formation induced from surgical placement of a functional prosthesis or fixation device (15), in tissue within or about the device due to its targeted radiation effects.
    • 插入装置(15)用于附接到天然组织或假体装置,并且将预定剂量的能量递送到目标组织。 插入装置(15)包括在插入装置(15)内的能量源材料,其将预定剂量的能量递送到目标组织,同时使非靶向组织的暴露最小化。 目标组织具有已知的放射反应曲线并且与目标组织相邻。 能量源材料与假体装置组合定义了实际的能量输送分布场。 能量输送分布场具有类似于目标组织的已知轮廓的构造。 规定剂量的能量从插入装置(15)内的能源材料施加并且被引导到目标组织。 通过使用能源材料的已知物理特性以及通过相对于目标组织放置能源材料来确定规定的能量剂量。 植入物系统减少由植入物引起的异位骨化的任何发生,抑制良性或恶性活细胞的生长或迁移,并且最小化甚至消除由功能性假体或固定装置的手术放置引起的感染过程或延迟的瘢痕疙瘩或瘢痕形成( 15),由于其目标的辐射效应,在装置内或周围的组织中。