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    • 4. 发明申请
    • キサントン誘導体
    • XANTHONE DERIVATIVE
    • WO2003062440A1
    • 2003-07-31
    • PCT/JP2003/000438
    • 2003-01-20
    • 住友製薬株式会社宮内 浩
    • 宮内 浩
    • C12P17/06
    • C12P17/06C07D311/86
    • A compound represented by the following formula: (1) wherein R 3 represents hydrogen, carboxy, alkoxycarbonyl, etc.; R 4 represents hydrogen, hydroxy, alkanoyloxy, cycloalkylcarbonyloxy, aroyloxy, etc.; R 5 represents hydrogen, alkanoyl, cycloalkylcarbonyl, aroyl, etc.; and R 1 and R 2 are as follows: R 1 represents methyl and R 2 represents a group represented by the formula (3) etc., or R 1 represents a group represented by the formula (8) etc., and R 2 represents acetyl. The xanthone derivative is useful as a preventive or therapeutic agent for various neuropathic diseases/neurodegenerative diseases.
    • 由下式表示的化合物:(1)其中R 3表示氢,羧基,烷氧基羰基等; R 4代表氢,羟基,烷酰氧基,环烷基羰氧基,芳酰氧基等; R 5代表氢,烷酰基,环烷基羰基,芳酰基等; R 1和R 2如下:R 1表示甲基,R 2表示由下式表示的基团: 式(3)等或R 1表示由式(8)等表示的基团,R 2表示乙酰基。 呫吨酮衍生物可用作各种神经病变/神经变性疾病的预防或治疗剂。