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1. 发明申请

WO1989010101A1 MECHANICAL FIXATION OF PROSTHETIC LIGAMENT 审中-公开
标题翻译：机体固定机制
公开(公告)号：WO1989010101A1
公开(公告)日：1989-11-02
申请号：PCT/GB1989000454
申请日：1989-04-28
申请人： SEEDHOM, Bahaa, Botros
IPC分类号： A61F02/08
CPC分类号： A61F2/0811 , A61F2/08 , A61F2002/0829 , A61F2002/087 , A61F2002/0882 , A61F2002/0888 , A61F2250/0037
摘要： There is disclosed a prosthetic ligament (20) made of woven implantable material and which can be introduced into a passage (11) formed in a pair of adjoining bones (12, 13) of a bone joint, there being enlarged entrances (14) at each end of passage (11) to receive bone plugs (14a) for closing the entrances after the ligament has been introduced into the passage and the entrances. The ligament (20, 30) comprises a main tubular portion (21) to be located in the passage (11) and having its axis extending generally longitudinally of the ligament, and end portions (25) each intended to be located in a respective entrance (14) and to project therefrom for securement to the respective bone (12, 13) by mechanical fixation. At least one of the end portions (25) comprises a tubular portion (26) which extends transversely of the longitudinal axis and which is open at each end so as to receive an elongate anchoring element (a cross piece of a staple (28) or an anchoring bar (31) of a mechanical fixation arrangement which is operative to make a mechanical fixation of the end portion to the respective bone, and there is also provided a strengthened section (27) in the form of a dense weave section which is adjacent to the transverse tubular portion (26) and which can therefore withstand tensile load which may be applied in use to the ligament.

2. 发明申请

WO2013017835A1 CONNECTIVE TISSUE REPAIR 审中-公开
标题翻译：连接组织修复
公开(公告)号：WO2013017835A1
公开(公告)日：2013-02-07
申请号：PCT/GB2012/051747
申请日：2012-07-20
申请人： XIROS LIMITED , SEEDHOM, Bahaa Botros
发明人： SEEDHOM, Bahaa Botros
IPC分类号： A61F2/00 , A61F2/08
CPC分类号： A61F2/08 , A61F2/0063 , A61F2002/087 , A61F2240/001 , B29C70/08 , B29L2031/7546
摘要： The invention relates to an implantable prosthetic device, a patch, for the repair of connective tissue in an animal or a human. In one embodiment, a biocompatible repair patch (10) for repair of human or animal tissue is disclosed which comprises a tensile load- bearing component in the form of a pre-formed array (13) of a looped configuration in a desired pattern and having at least one return end, said array being formed of an elongate filamentary material; and a base layer (1 1) of non- woven fibrous material. The pre-formed array is attached to one surface of the base layer so that the pre-formed array retains its configuration while being handled during surgery. The at least one return end serves to receive a suture or the like to attach the patch to tissue. The fibres of the base layer are entangled with the looped configuration so as to attach the array to the base layer and substantially to maintain the desired pattern.
摘要翻译：本发明涉及一种用于修复动物或人类中的结缔组织的可植入假体装置，补片。在一个实施方案中，公开了一种用于人或动物组织修复的生物相容性修复贴片（10），其包括具有期望图案的环形构型的预先形成的阵列（13）形式的拉伸承载部件，并且具有至少一个返回端，所述阵列由细长的丝状材料形成; 和非织造纤维材料的基层（11）。预先形成的阵列附接到基底层的一个表面，使得预先形成的阵列在手术期间被处理时保持其构造。至少一个返回端用于接收缝合线等以将贴片附接到组织。基层的纤维与环形结构缠结，以便将阵列附接到基层并且基本上保持所需的图案。

3. 发明申请

WO2010049737A3 TUBULAR IMPLANTABLE CORD 审中-公开
公开(公告)号：WO2010049737A3
公开(公告)日：2010-05-06
申请号：PCT/GB2009/051459
申请日：2009-10-29
申请人： XIROS LIMITED , BEEVERS, David , SEEDHOM, BAHAA, Botros
发明人： BEEVERS, David , SEEDHOM, BAHAA, Botros
IPC分类号： A61F2/08
摘要： A surgical cord (100, 200,101) comprising a tubular section along its main length and comprising regions (600, 608, 601) exhibiting different mechanical and/or physical properties resultant from a change in material, pattern type, pattern density, yarn thickness and/or shape. Different regions along the length of the cord are optimised to provide the required extensibility, abrasion resistance and/or stiffness. A tissue core (904) may be incorporated within the tubular cord structure and a means of indicating the tensile loading force applied to the cord may be provided.

4. 发明申请

WO1992016167A1 IMPLANTABLE FIXING DEVICE FOR KNEE LIGAMENT PROSTHESIS 审中-公开
标题翻译：可伸缩的固定装置，用于KNEE LIGAMENT PROSTHESISIS
公开(公告)号：WO1992016167A1
公开(公告)日：1992-10-01
申请号：PCT/GB1992000469
申请日：1992-03-16
申请人： SEEDHOM, Bahaa, Botros , COLLINS, Simon
IPC分类号： A61F02/08
CPC分类号： A61F2/0811 , A61F2002/0829 , A61F2002/0852 , A61F2002/0858 , A61F2002/0882 , A61F2002/0888
摘要： A prosthetic ligament fixation system which comprises a prosthetic ligament (15) which can be taken through first and second bone tunnels (13, 14) formed in adjoining bones (11, 12) of a bone joint (10), a first fixing device (16) for holding one end of the ligament at or near to one end (19) of the first bone tunnel (13) and intended to seat itself on the surface of the bone surrounding entrance (19) to the bone tunnel (13) and a second fixing device (18) for holding an opposite end of the ligament (15) at or near to one end of the second bone tunnel (14) in which the first fixing device comprises an annular seating device (20) with an annular bearing surface (20a) on its underside to seat on the surrounding surface of the bone at the entrance (19) to the first bone tunnel (13) and also comprising a U-shaped cradle (22) adjustably mounted on, and extending away from seating device (20) to be located in the first bone tunnel (13) whereby the cradle (22) holds one end of the ligament but is capable of adjusting its position relative to the seating device (20) if necessary, so that the seating device can apply substantially uniform bearing pressure while the ligament (15) can extend along the bone tunnels (13, 14) without coming into engagement with the walls of the tunnels.
摘要翻译：一种假肢韧带固定系统，其包括可以穿过形成在骨关节（10）的相邻骨头（11,12）中的第一和第二骨隧道（13,14）的修复韧带（15），第一固定装置 16），用于将所述韧带的一端保持在所述第一骨隧道（13）的一端（19）处或附近，并且将其本身固定在所述骨周围入口（19）的表面上至所述骨隧道（13），并且第二固定装置（18），用于将所述韧带（15）的相对端保持在所述第二骨隧道（14）的一端处或附近，其中所述第一固定装置包括环形座位装置（20），其具有环形轴承在其下侧的表面（20a）位于入口（19）处的第一骨隧道（13）处的骨的周围表面上，并且还包括可调节地安装在座椅上并远离座椅的U形支架（22）装置（20）位于第一骨隧道（13）中，由此托架（22）保持韧带的一端如果需要，其能够相对于座椅装置（20）调节其位置，使得座椅装置可以施加基本均匀的承受压力，同时韧带（15）可以沿着骨隧道（13,14）延伸而不进入接合与隧道的墙壁。

5. 发明申请

WO2012140427A1 IMPLANTABLE SURGICAL CORD ANCHOR 审中-公开
标题翻译：可植入手术线锚
公开(公告)号：WO2012140427A1
公开(公告)日：2012-10-18
申请号：PCT/GB2012/050805
申请日：2012-04-12
申请人： XIROS LIMITED , LORRISON, Jonathan Charles , SEEDHOM, Bahaa Botros , HOGG, Alexander John , BEEVERS, David John
发明人： LORRISON, Jonathan Charles , SEEDHOM, Bahaa Botros , HOGG, Alexander John , BEEVERS, David John
IPC分类号： A61B17/04
CPC分类号： A61B17/0401 , A61B17/0469 , A61B2017/0414 , A61B2017/0417 , A61B2017/0435 , A61B2017/044 , A61B2017/0445 , A61B2017/045 , A61B2017/0451 , A61B2017/0453 , B33Y80/00
摘要： This invention relates to implantable cord anchorage devices for animals and humans and methods of manufacturing the same, optionally by using rapid manufacturing technology. One implantable surgical cord anchor (10) is disclosed which comprises: a main body (12) to be pressed or screwed into biological tissue; an internal cavity (14) extending internally along a region of the main body; an inner component (16) movable both axially and rotationally within the cavity of the main body such that the inner component may be inserted and withdrawn from the inner cavity via axial movement and rotated when inserted within the inner cavity; and cooperating locking components (18, 20) provided at an internal facing surface (22) of the inner cavity of the main body and an external facing surface (24) of the inner component such that the inner component is capable of being locked in position axially within the main body via engagement of the locking components.
摘要翻译：本发明涉及用于动物和人类的可植入脐带固定装置及其制造方法，可选地通过使用快速制造技术。公开了一种植入式外科手术绳锚（10），其包括：被压制或旋入生物组织的主体（12）; 沿着主体的区域内部延伸的内部空腔（14）; 内部构件（16），其可在主体的空腔内轴向和旋转地移动，使得内部构件可以通过轴向移动从内腔插入和退出，并且当插入内腔中时旋转; 以及设置在主体的内腔的内表面（22）处的配合的锁定部件（18,20）和内部部件的外部相对表面（24），使得内部部件能够被锁定就位通过锁定部件的接合而在主体内轴向地移动。

6. 发明申请

WO2010049737A2 TUBULAR IMPLANTABLE CORD 审中-公开
标题翻译：管状可植入
公开(公告)号：WO2010049737A2
公开(公告)日：2010-05-06
申请号：PCT/GB2009051459
申请日：2009-10-29
申请人： XIROS LTD , BEEVERS DAVID , SEEDHOM BAHAA BOTROS
发明人： BEEVERS DAVID , SEEDHOM BAHAA BOTROS
IPC分类号： A61F2/08
CPC分类号： A61F2/08 , A61B2017/06185
摘要： A surgical cord comprising a tubular section along its main length and comprising regions exhibiting different mechanical and/or physical properties resultant from a change in material, pattern type, pattern density, yarn thickness and/or shape. Different regions along the length of the cord are optimised to provide the required extensibility, abrasion resistance and/or stiffness. A tissue core may be incorporated within the tubular cord structure and a means of indicating the tensile loading force applied to the cord may be provided.
摘要翻译：一种手术线，其包括沿其主要长度的管状部分，并且包括由材料，图案类型，图案密度，纱线厚度和/或形状的变化产生的不同的机械和/或物理性质的区域。沿着帘线长度的不同区域被优化以提供所需的延展性，耐磨性和/或刚度。组织芯可以结合在管状线结构中，并且可以提供指示施加到绳索的拉伸载荷力的装置。

7. 发明申请

WO2005051245A2 SURGICAL INSTRUMENTS FOR USE IN THE IMPLANTATION OF TISSUE REPAIR KIT 审中-公开
标题翻译：手术器械用于组织修复套件的植入
公开(公告)号：WO2005051245A2
公开(公告)日：2005-06-09
申请号：PCT/GB2004004537
申请日：2004-10-27
申请人： XIROS PLC , SEEDHOM BAHAA BOTROS , LORRISON JONATHAN CHARLES , BRYANT JULIAN , BEEVERS DAVID
发明人： SEEDHOM BAHAA BOTROS , LORRISON JONATHAN CHARLES , BRYANT JULIAN , BEEVERS DAVID
IPC分类号： A61B17/16 , A61B17/17 , A61F2/30 , A61F2/46
CPC分类号： A61B17/1637 , A61B17/17 , A61F2/30756 , A61F2002/30601
摘要： A set of surgical instruments for use in the implantation of a tissue repair kit (9, 11) after preparation of a bone site (1, 3, 5) having damaged tissue, in which damaged tissue is first removed and an annular groove (7) is formed around the defect site prior to application of the repair kit comprising a bio-compatible pad (9) to fit on the prepared bone site, and an overlying cover sheet (11) to fit in the groove, and the set of surgical instruments comprising: an introducer cylinder (44) having a hollow driving head (44a) at one end for introducing an outer portion (11a) of the cover sheet into the groove (7); a plunger (43) relatively slidable within the cylinder (44) and having a delivery end (43a) engageable with the cover sheet so as to move a main portion (11b) of the cover sheet towards the bone site with the outer portion (11a) of the cover sheet trailing behind the main portion; and a pad-receiving recess defined between the delivery end (43a) of the plunger (43) and the inner wall of the cylinder (44) so that a pad (9) can be introduced into the recess to overlie the main portion (11b) of the cover sheet (11); and a bone site preparation device (30) for removing damaged tissue from the bone site (1, 3) and for forming the annular groove (7) around the site prior to use of the introducer cylinder (44) and plunger (43).
摘要翻译：在制备具有受损组织的骨部位（1,3,5）之后，用于植入组织修复套件（9,11）的一组手术器械，其中首先移除受损组织，并且将环形凹槽（7 ）在应用修复套件之前在缺损部位周围形成，所述修复套件包括适合于准备好的骨骼部位的生物相容垫（9）以及配合在所述凹槽中的覆盖覆盖片（11），并且所述一组手术其包括：在一端具有中空驱动头（44a）的导引器圆筒（44），用于将覆盖片的外部（11a）引入凹槽（7）中; 柱塞（43），其可在缸体（44）内相对滑动并具有可与覆盖片接合的输送端（43a），从而使覆盖片的主要部分（11b）朝向具有外部部分（11a）的骨骼部位）在主要部分后面延伸的覆盖片; （43）的输出端（43a）和圆筒（44）的内壁之间形成一个垫接收凹槽，从而垫（9）可以被引入到凹槽中以覆盖主体部分（11b ）的盖片（11）; 以及用于从骨骼部位（1,3）去除受损组织并且在使用导引器柱体（44）和柱塞（43）之前围绕该部位形成环形凹槽（7）的骨骼部位准备设备（30）。

8. 发明申请

WO2005051242A1 REPAIR OF DAMAGED TISSUE ON A BONE SITE 审中-公开
标题翻译：修复骨质疏松的组织
公开(公告)号：WO2005051242A1
公开(公告)日：2005-06-09
申请号：PCT/GB2004/004536
申请日：2004-10-27
申请人： XIROS PLC , SEEDHOM, Bahaa, Botros , LORRISON, Jonathan, Charles
发明人： SEEDHOM, Bahaa, Botros , LORRISON, Jonathan, Charles
IPC分类号： A61F2/30
CPC分类号： A61F2/4618 , A61B17/06166 , A61F2/30749 , A61F2/30756 , A61F2002/30113 , A61F2002/30131 , A61F2002/30143 , A61F2002/30144 , A61F2002/302 , A61F2002/30225 , A61F2002/30326 , A61F2002/30448 , A61F2002/30462 , A61F2002/30599 , A61F2002/30611 , A61F2002/30612 , A61F2002/30751 , A61F2002/30759 , A61F2002/30762 , A61F2002/30766 , A61F2220/0008 , A61F2220/005 , A61F2220/0075 , A61F2230/0006 , A61F2230/0013 , A61F2230/0017 , A61F2230/0065 , A61F2230/0069 , A61F2250/0037 , A61F2250/0063
摘要： A repair kit (10) for use in the repair of damaged cartilage present at or on the surface of a bone site (20) in an animal or human, in which the damaged cartilage is removed from the site and a groove (25) is formed about the site and into the bone (20) prior to implantation of the repair kit (10), and said repair kit comprising: a pad (11) of bio-compatible material shaped and dimensioned to occupy at least part of the site from which the damaged tissue has been removed; elongate connecting portions (14) attached to the periphery of the pad (11) in an array corresponding in shape to the groove (25), said portions being intended to extend away from the general plane of the pad so as to be introduced into the groove and to be anchored therein; and a retaining element (26) slidable depthwise of the groove (25) in order to anchor at least some of the connecting portions (14) in the groove (25) and thereby locate and retain the pad (11) in said part of the bone site. There is also disclosed a method of preparation of the bone site prior to implantation, and also an implant delivery device (46), on which the repair kit can be temporarily stored, and which also serves to deliver the pad, the elongate connecting portions (14) and the retaining element (47) on to the prepared site.
摘要翻译：用于修复存在于动物或人的骨部位（20）表面上或其表面的受损软骨的修复工具（10），其中从现场移除受损的软骨和凹槽（25）是在植入修复套件（10）之前围绕该部位形成并进入骨骼（20），并且所述修复套件包括：生物相容性材料的垫（11），其形状和尺寸被设计成占据所述部位的至少一部分，损坏的组织被去除; 细长的连接部分（14）以与凹槽（25）的形状相对应的阵列附接到焊盘（11）的周边，所述部分旨在远离焊盘的总平面延伸，以便被引入到凹槽并锚定在其中; 以及保持元件（26），其能够沿所述凹槽（25）的深度方向滑动，以便将所述凹槽（25）中的至少一些所述连接部分（14）锚固，从而将所述垫（11）定位并保持在所述部分骨骼部位。还公开了在植入之前制备骨部位的方法，以及植入物递送装置（46），修复工具可以临时存储在该植入物输送装置上，并且还用于输送垫，细长连接部分 14）和保持元件（47）放置在准备的位置上。

9. 发明申请

WO1998012991A1 ATTACHMENT DEVICE FOR USE IN THE IMPLANTATION OF PROSTHETIC LIGAMENT 审中-公开
标题翻译：附着装置，用于植入浮雕生物
公开(公告)号：WO1998012991A1
公开(公告)日：1998-04-02
申请号：PCT/GB1997002612
申请日：1997-09-26
申请人： NEOLIGAMENTS LIMITED , SEEDHOM, Bahaa, Botros
发明人： NEOLIGAMENTS LIMITED
IPC分类号： A61F02/08
CPC分类号： A61F2/0811 , A61F2/08 , A61F2002/0852 , A61F2002/0882
摘要： An attachment device for use in an implantation system which includes a prosthetic ligament (21), in order to guide the ligament to a required position in a bone tunnel, formed in a bone joint (10) between two adjacent bones (11, 12), and to anchor one end of the ligament, said device comprising: an elongate guide element (25, 125) which is manipulatable between a pulling position in which its longitudinal axis extends generally parallel to the pulling direction and an anchoring position in which its longitudinal axis extends transversely of the pulling direction; a connecting loop (27, 129) of flexible and implantable material which is connected, or connectable, at one end to the guide element (25, 125) and at its other end is connectable to one end of the prosthetic ligament (21) to be implanted, said loop being assembled from a fibre bundle of twisted yarn; connecting apertures (26, 126) formed in the guide elements (25, 125) which permit the loop (27, 129) to be connected thereto; and connecting means (26, 127) provided on the guide elements (25, 125) to permit pulling means (22, 128) to be connected to the element in order to pull the guide element, and trailing implantation system connected thereto, through the bone tunnels with the guide element orientated so that its longitudinal axis extends generally parallel to the pulling direction until the element emerges from the mouth at one end of one of the tunnels, whereby the guide element is manipulatable by the pulling means so as to overlie the mouth and thereby anchor one end of the implantation system.
摘要翻译：一种用于植入系统的附接装置，其包括修复韧带（21），以便将韧带引导到形成在两个相邻骨头（11,12）之间的骨关节（10）中的骨隧道中的所需位置，并且固定所述韧带的一端，所述装置包括：细长引导元件（25,125），其可在其纵向轴线基本上平行于所述牵引方向延伸的拉动位置与所述拉伸位置之间可操纵，在所述锚定位置，轴线沿牵引方向横向延伸; 柔性和可植入材料的连接环（27,129）在一端连接或连接到引导元件（25,125）并且在其另一端处可连接到假肢韧带（21）的一端至被植入，所述环路由加捻纱线的纤维束组装; 形成在引导元件（25,125）中的连接孔（26,126），其允许环路（27,129）与其连接; 以及设置在引导元件（25,125）上的连接装置（26,127），以允许牵引装置（22,128）连接到元件，以便拉动引导元件，并且通过所述引导元件与其连接的拖曳植入系统具有引导元件的骨隧道定向成使得其纵向轴线大致平行于牵引方向延伸，直到元件在一个隧道的一端处从嘴部露出，由此引导元件可被拉动装置操纵以覆盖从而锚定植入系统的一端。

10. 发明申请

WO1991006249A1 LIGAMENT FIXATION DEVICE 审中-公开
标题翻译：大容量固定装置
公开(公告)号：WO1991006249A1
公开(公告)日：1991-05-16
申请号：PCT/GB1990001694
申请日：1990-11-05
申请人： SEEDHOM, Bahaa, Botros , COLLINS, Simom , SWAN, Anthony, Charles
IPC分类号： A61B17/064
CPC分类号： A61F2/0805 , A61B17/0642 , A61B17/88 , A61F2/0811 , A61F2002/0829 , A61F2002/0852 , A61F2002/0888
摘要： There is disclosed a fixation device (100) for securing a prosthetic ligament (103) to a bone (104) and which comprises a bone staple (101) having a head portion (105) by means of which the staple can be driven into the bone, and a pair of legs (106) extending from the head (105) and having ends (107) engageable into the bone, characterised by a stirrup (102) for guiding the driving movement of the staple (101) and arranged also to cooperate with the staple in order to enable the prosthetic ligament (103) to engage the staple and the stirrup and to be securable to the bone (104) upon completion of driving of the staple (101) into the bone, the stirrup comprising two generally parallel side portions (108) which define guides (109) to receive the legs (106) of the stapleand to guide the driving movement of the legs, and also defining an aperture (110) through which the ligament (103) can be taken prior to securement of the ligament to the bone.
摘要翻译：公开了一种用于将假体韧带（103）固定到骨头（104）上的固定装置（100），该固定装置包括具有头部部分（105）的骨钉（101），通过该头钉部分可将钉子驱动到骨头和从头部（105）延伸并且具有可接合到骨中的端部（107）的一对腿部（106），其特征在于，用于引导钉（101）的驱动运动的箍筋（102）并且还布置与订书钉配合以使得当钉子（101）进入骨骼完成时，假肢韧带（103）能够接合钉和箍筋并且可固定到骨骼（104）上，马镫包括两个通常平行侧部分（108），其限定引导件（109）以接收钉臂的腿部（106）以引导腿部的驱动运动，并且还限定孔（110），先前可以将韧带（103）从该孔将韧带固定在骨上。

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