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1. 发明申请

WO2013017836A2 CONNECTIVE TISSUE REPAIR PAD 审中-公开
标题翻译：连接组织修复垫
公开(公告)号：WO2013017836A2
公开(公告)日：2013-02-07
申请号：PCT/GB2012/051749
申请日：2012-07-20
申请人： XIROS LIMITED , HACKNEY, Roger Graham , BEEVERS, David John , TIDBALL, Lauren
发明人： HACKNEY, Roger Graham , BEEVERS, David John , TIDBALL, Lauren
IPC分类号： A61F2/00 , A61F2/08
CPC分类号： A61F2/08 , A61F2/0063 , A61F2/0077 , A61F2002/0086 , A61F2220/0008 , A61F2220/0075
摘要： The invention relates to an implantable prosthetic device for the repair of connective tissue in an animal or a human. In one embodiment, an implantable prosthetic device (100) for the repair of connective tissue (500) in an animal or human is disclosed which comprises a biocompatible pad (101) having an open structure to provide a scaffold for the in-growth of tissue into the pad; and a reinforcement region (206) attached to or formed integrally with the pad. The device is arranged so that it can be attached to tissue by forming a puncture (301) either a) within the reinforcement region, or b) in an area of the pad which is inboard of the reinforcement region, so that a suture (300) can be located through the puncture, the reinforcement region serving to support tensile loading in the device during use by resisting pull-through of the suture.
摘要翻译：本发明涉及一种用于修复动物或人类结缔组织的可植入假体装置。在一个实施例中，公开了一种用于修复动物或人体中的结缔组织（500）的可植入假体装置（100），其包括具有开放结构的生物相容垫（101），以提供用于组织向内生长的支架进入垫子; 和附接到所述衬垫或与所述衬垫一体形成的增强区域（206）。该装置被布置为使得其可以通过以下方式附接到组织上：a）在增强区域内，或者b）在增强区域的内侧的衬垫的区域中，从而缝合线（300））可以穿过穿孔定位，加强区域用于在使用期间通过抵抗穿过缝线来支撑装置中的拉伸负载。

2. 发明申请

WO2010100488A1 HIGH STRENGTH SUTURE 审中-公开
标题翻译：高强度
公开(公告)号：WO2010100488A1
公开(公告)日：2010-09-10
申请号：PCT/GB2010/050369
申请日：2010-03-03
申请人： XIROS LIMITED , BEEVERS, David , CALLOWAY, Lauren
发明人： BEEVERS, David , CALLOWAY, Lauren
IPC分类号： A61B17/06
CPC分类号： A61B17/06166 , A61B90/92 , A61B2017/06185 , D04C1/12 , D10B2403/02411 , D10B2509/04
摘要： A suture comprising an elongate tubular sheath formed from a plurality of braided yarn strands a plurality of axial yarn strands overlapping the braided yarn strands and aligned with the longitudinal axis of the elongate tubular sheath and transverse to the braided yarn strands and a core positioned within the tubular sheath, the core formed from a plurality of yarn strands extending longitudinally within the tubular sheath. Additionally, both axial and braided yarns may be incorporated within the suture having different denier. Different coloured yarn strands may also be incorporated within the outer tubular sheath to create repeating patterns along regions of the suture.
摘要翻译：一种缝合线，其包括由多根编织纱股线形成的细长管状护套，多条纱线与多条编织纱线重叠并与细长管状护套的纵向轴线相对准，横向于编织纱股线，管状护套，芯部由在管状护套内纵向延伸的多条纱股线形成。此外，轴向和编织纱线可以并入具有不同旦数的缝线内。不同的着色纱线也可以并入外管状护套中以沿着缝合线的区域产生重复图案。

3. 发明申请

WO2005051245A3 SURGICAL INSTRUMENTS FOR USE IN THE IMPLANTATION OF TISSUE REPAIR KIT 审中-公开
公开(公告)号：WO2005051245A3
公开(公告)日：2005-06-09
申请号：PCT/GB2004/004537
申请日：2004-10-27
申请人： XIROS PLC , SEEDHOM, Bahaa, Botros , LORRISON, Jonathan, Charles , BRYANT, Julian , BEEVERS, David
发明人： SEEDHOM, Bahaa, Botros , LORRISON, Jonathan, Charles , BRYANT, Julian , BEEVERS, David
IPC分类号： A61F2/46
摘要： A set of surgical instruments for use in the implantation of a tissue repair kit (9, 11) after preparation of a bone site (1, 3, 5) having damaged tissue, in which damaged tissue is first removed and an annular groove (7) is formed around the defect site prior to application of the repair kit comprising a bio-compatible pad (9) to fit on the prepared bone site, and an overlying cover sheet (11) to fit in the groove, and the set of surgical instruments comprising: an introducer cylinder (44) having a hollow driving head (44a) at one end for introducing an outer portion (11a) of the cover sheet into the groove (7); a plunger (43) relatively slidable within the cylinder (44) and having a delivery end (43a) engageable with the cover sheet so as to move a main portion (11b) of the cover sheet towards the bone site with the outer portion (11a) of the cover sheet trailing behind the main portion; and a pad-receiving recess defined between the delivery end (43a) of the plunger (43) and the inner wall of the cylinder (44) so that a pad (9) can be introduced into the recess to overlie the main portion (11b) of the cover sheet (11); and a bone site preparation device (30) for removing damaged tissue from the bone site (1, 3) and for forming the annular groove (7) around the site prior to use of the introducer cylinder (44) and plunger (43).

4. 发明申请

WO1995033425A1 PROSTHETIC FINGER JOINT 审中-公开
公开(公告)号：WO1995033425A1
公开(公告)日：1995-12-14
申请号：PCT/GB1995001341
申请日：1995-06-08
申请人： UNIVERSITY OF LEEDS , BEEVERS, David, John
发明人： UNIVERSITY OF LEEDS
IPC分类号： A61F02/42
CPC分类号： A61F2/4241 , A61F2002/30153 , A61F2002/30154 , A61F2002/30354 , A61F2002/30367 , A61F2002/30377 , A61F2002/30574 , A61F2002/30604 , A61F2002/30616 , A61F2002/30795 , A61F2002/30919 , A61F2002/4251 , A61F2220/0033 , A61F2230/0019 , A61F2230/0021 , A61F2310/00017 , A61F2310/00029
摘要： A finger joint prosthesis for implantation between a first bone and a second bone, the prosthesis comprising a first component capable of being operatively connected to said first bone, and a second component capable of being operatively connected to said second bone, each component comprising an anchor part for connection to said first bone and a bearing part for pivotal engagement with the bearing part of the other component, the anchor and bearing parts of the first component being distinct elements for connection together so that, when the implanted joint is in use, there is no relative movement between said elements. The joint is usually a metacarpophalangeal joint and the anchor part of the first component is, preferably, a sleeve fitted into the metacarpal bone to secure the replacement metacarpal head. The two-part first bone component allows replacement of worn heads without disturbing the sleeve anchor.
摘要翻译：一种用于在第一骨和第二骨之间植入的手指关节假体，所述假体包括能够可操作地连接到所述第一骨的第一部件和能够可操作地连接到所述第二骨的第二部件，每个部件包括锚固件用于连接到所述第一骨骼的部分和用于与另一部件的轴承部分枢转接合的支承部件，第一部件的锚固件和支承部件是用于连接在一起的不同元件，使得当使用植入的接头时，在所述元件之间没有相对运动。关节通常是掌指关节，并且第一部件的锚固部分优选地是装配到掌骨中的套筒以固定替换掌骨头。两部分第一个骨骼部件允许更换磨损的头部，而不会妨碍套筒锚固件。

5. 发明申请

WO2013017836A3 CONNECTIVE TISSUE REPAIR PAD 审中-公开
标题翻译：连接组织修复垫
公开(公告)号：WO2013017836A3
公开(公告)日：2013-04-04
申请号：PCT/GB2012051749
申请日：2012-07-20
申请人： XIROS LTD , HACKNEY ROGER GRAHAM , BEEVERS DAVID JOHN , TIDBALL LAUREN
发明人： HACKNEY ROGER GRAHAM , BEEVERS DAVID JOHN , TIDBALL LAUREN
IPC分类号： A61F2/00 , A61F2/08
CPC分类号： A61F2/08 , A61F2/0063 , A61F2/0077 , A61F2002/0086 , A61F2220/0008 , A61F2220/0075
摘要： The invention relates to an implantable prosthetic device for the repair of connective tissue in an animal or a human. In one embodiment, an implantable prosthetic device (100) for the repair of connective tissue (500) in an animal or human is disclosed which comprises a biocompatible pad (101) having an open structure to provide a scaffold for the in-growth of tissue into the pad; and a reinforcement region (206) attached to or formed integrally with the pad. The device is arranged so that it can be attached to tissue by forming a puncture (301) either a) within the reinforcement region, or b) in an area of the pad which is inboard of the reinforcement region, so that a suture (300) can be located through the puncture, the reinforcement region serving to support tensile loading in the device during use by resisting pull-through of the suture.
摘要翻译：本发明涉及一种用于修复动物或人类中的结缔组织的可植入假体装置。在一个实施例中，公开了一种用于修复动物或人体中的结缔组织（500）的可植入假体装置（100），其包括具有开放结构的生物相容性垫（101），以提供用于组织生长的支架进入垫以及附接到所述垫或与所述垫一体形成的加强区域（206）。该装置被布置成使得其可以通过在加强区域内或在b）在加强区域内的垫的区域中形成穿刺（301）而附接到组织，使得缝合线（300 ）可以通过穿刺定位，加强区域用于在使用期间通过阻止缝合线的穿通来支撑装置中的拉伸载荷。

6. 发明申请

WO2010049737A3 TUBULAR IMPLANTABLE CORD 审中-公开
公开(公告)号：WO2010049737A3
公开(公告)日：2010-05-06
申请号：PCT/GB2009/051459
申请日：2009-10-29
申请人： XIROS LIMITED , BEEVERS, David , SEEDHOM, BAHAA, Botros
发明人： BEEVERS, David , SEEDHOM, BAHAA, Botros
IPC分类号： A61F2/08
摘要： A surgical cord (100, 200,101) comprising a tubular section along its main length and comprising regions (600, 608, 601) exhibiting different mechanical and/or physical properties resultant from a change in material, pattern type, pattern density, yarn thickness and/or shape. Different regions along the length of the cord are optimised to provide the required extensibility, abrasion resistance and/or stiffness. A tissue core (904) may be incorporated within the tubular cord structure and a means of indicating the tensile loading force applied to the cord may be provided.

7. 发明申请

WO2009109778A2 IMPLANTABLE PROSTHETIC CORD 审中-公开
标题翻译：可植入的假牙
公开(公告)号：WO2009109778A2
公开(公告)日：2009-09-11
申请号：PCT/GB2009050214
申请日：2009-03-04
申请人： XIROS PLC , BEEVERS DAVID
发明人： BEEVERS DAVID
IPC分类号： A61L17/04 , D01F8/14
CPC分类号： A61F2/08 , A61F2/0811 , A61F2002/087 , A61F2002/0888 , A61F2250/0026 , A61F2250/0028 , D07B1/02
摘要： A medical cord and surgical procedure for the connection of a first tissue site to a second tissue site. The cord comprises a main length having a width and end portions having respective widths being less than the width of the main length. This provides a medical cord that is easy to manipulate during surgical procedures in which the cord may be required to be threaded through apertures and tunnels. The cord is particularly suitable to attach soft tissue, including ligaments and tendons to bone anchorsites and provides a prosthetic scaffold to facilitate tissue ingrowth at the repair site.
摘要翻译：用于将第一组织部位连接到第二组织部位的医疗用绳索和外科手术。帘线包括具有宽度的主长度和具有小于主长度宽度的相应宽度的端部。这提供了在手术过程中容易操作的医疗线，其中绳索可能需要穿过孔和隧道。绳索特别适合于将软组织（包括韧带和腱）附着到骨锚固件上，并提供假体支架以便于修复部位的组织向内生长。

8. 发明申请

WO2012140427A1 IMPLANTABLE SURGICAL CORD ANCHOR 审中-公开
标题翻译：可植入手术线锚
公开(公告)号：WO2012140427A1
公开(公告)日：2012-10-18
申请号：PCT/GB2012/050805
申请日：2012-04-12
申请人： XIROS LIMITED , LORRISON, Jonathan Charles , SEEDHOM, Bahaa Botros , HOGG, Alexander John , BEEVERS, David John
发明人： LORRISON, Jonathan Charles , SEEDHOM, Bahaa Botros , HOGG, Alexander John , BEEVERS, David John
IPC分类号： A61B17/04
CPC分类号： A61B17/0401 , A61B17/0469 , A61B2017/0414 , A61B2017/0417 , A61B2017/0435 , A61B2017/044 , A61B2017/0445 , A61B2017/045 , A61B2017/0451 , A61B2017/0453 , B33Y80/00
摘要： This invention relates to implantable cord anchorage devices for animals and humans and methods of manufacturing the same, optionally by using rapid manufacturing technology. One implantable surgical cord anchor (10) is disclosed which comprises: a main body (12) to be pressed or screwed into biological tissue; an internal cavity (14) extending internally along a region of the main body; an inner component (16) movable both axially and rotationally within the cavity of the main body such that the inner component may be inserted and withdrawn from the inner cavity via axial movement and rotated when inserted within the inner cavity; and cooperating locking components (18, 20) provided at an internal facing surface (22) of the inner cavity of the main body and an external facing surface (24) of the inner component such that the inner component is capable of being locked in position axially within the main body via engagement of the locking components.
摘要翻译：本发明涉及用于动物和人类的可植入脐带固定装置及其制造方法，可选地通过使用快速制造技术。公开了一种植入式外科手术绳锚（10），其包括：被压制或旋入生物组织的主体（12）; 沿着主体的区域内部延伸的内部空腔（14）; 内部构件（16），其可在主体的空腔内轴向和旋转地移动，使得内部构件可以通过轴向移动从内腔插入和退出，并且当插入内腔中时旋转; 以及设置在主体的内腔的内表面（22）处的配合的锁定部件（18,20）和内部部件的外部相对表面（24），使得内部部件能够被锁定就位通过锁定部件的接合而在主体内轴向地移动。

9. 发明申请

WO2010049737A2 TUBULAR IMPLANTABLE CORD 审中-公开
标题翻译：管状可植入
公开(公告)号：WO2010049737A2
公开(公告)日：2010-05-06
申请号：PCT/GB2009051459
申请日：2009-10-29
申请人： XIROS LTD , BEEVERS DAVID , SEEDHOM BAHAA BOTROS
发明人： BEEVERS DAVID , SEEDHOM BAHAA BOTROS
IPC分类号： A61F2/08
CPC分类号： A61F2/08 , A61B2017/06185
摘要： A surgical cord comprising a tubular section along its main length and comprising regions exhibiting different mechanical and/or physical properties resultant from a change in material, pattern type, pattern density, yarn thickness and/or shape. Different regions along the length of the cord are optimised to provide the required extensibility, abrasion resistance and/or stiffness. A tissue core may be incorporated within the tubular cord structure and a means of indicating the tensile loading force applied to the cord may be provided.
摘要翻译：一种手术线，其包括沿其主要长度的管状部分，并且包括由材料，图案类型，图案密度，纱线厚度和/或形状的变化产生的不同的机械和/或物理性质的区域。沿着帘线长度的不同区域被优化以提供所需的延展性，耐磨性和/或刚度。组织芯可以结合在管状线结构中，并且可以提供指示施加到绳索的拉伸载荷力的装置。

10. 发明申请

WO2005051245A2 SURGICAL INSTRUMENTS FOR USE IN THE IMPLANTATION OF TISSUE REPAIR KIT 审中-公开
标题翻译：手术器械用于组织修复套件的植入
公开(公告)号：WO2005051245A2
公开(公告)日：2005-06-09
申请号：PCT/GB2004004537
申请日：2004-10-27
申请人： XIROS PLC , SEEDHOM BAHAA BOTROS , LORRISON JONATHAN CHARLES , BRYANT JULIAN , BEEVERS DAVID
发明人： SEEDHOM BAHAA BOTROS , LORRISON JONATHAN CHARLES , BRYANT JULIAN , BEEVERS DAVID
IPC分类号： A61B17/16 , A61B17/17 , A61F2/30 , A61F2/46
CPC分类号： A61B17/1637 , A61B17/17 , A61F2/30756 , A61F2002/30601
摘要： A set of surgical instruments for use in the implantation of a tissue repair kit (9, 11) after preparation of a bone site (1, 3, 5) having damaged tissue, in which damaged tissue is first removed and an annular groove (7) is formed around the defect site prior to application of the repair kit comprising a bio-compatible pad (9) to fit on the prepared bone site, and an overlying cover sheet (11) to fit in the groove, and the set of surgical instruments comprising: an introducer cylinder (44) having a hollow driving head (44a) at one end for introducing an outer portion (11a) of the cover sheet into the groove (7); a plunger (43) relatively slidable within the cylinder (44) and having a delivery end (43a) engageable with the cover sheet so as to move a main portion (11b) of the cover sheet towards the bone site with the outer portion (11a) of the cover sheet trailing behind the main portion; and a pad-receiving recess defined between the delivery end (43a) of the plunger (43) and the inner wall of the cylinder (44) so that a pad (9) can be introduced into the recess to overlie the main portion (11b) of the cover sheet (11); and a bone site preparation device (30) for removing damaged tissue from the bone site (1, 3) and for forming the annular groove (7) around the site prior to use of the introducer cylinder (44) and plunger (43).
摘要翻译：在制备具有受损组织的骨部位（1,3,5）之后，用于植入组织修复套件（9,11）的一组手术器械，其中首先移除受损组织，并且将环形凹槽（7 ）在应用修复套件之前在缺损部位周围形成，所述修复套件包括适合于准备好的骨骼部位的生物相容垫（9）以及配合在所述凹槽中的覆盖覆盖片（11），并且所述一组手术其包括：在一端具有中空驱动头（44a）的导引器圆筒（44），用于将覆盖片的外部（11a）引入凹槽（7）中; 柱塞（43），其可在缸体（44）内相对滑动并具有可与覆盖片接合的输送端（43a），从而使覆盖片的主要部分（11b）朝向具有外部部分（11a）的骨骼部位）在主要部分后面延伸的覆盖片; （43）的输出端（43a）和圆筒（44）的内壁之间形成一个垫接收凹槽，从而垫（9）可以被引入到凹槽中以覆盖主体部分（11b ）的盖片（11）; 以及用于从骨骼部位（1,3）去除受损组织并且在使用导引器柱体（44）和柱塞（43）之前围绕该部位形成环形凹槽（7）的骨骼部位准备设备（30）。

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