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1. 发明申请

WO1996026709A3 CLEAR ANTIPERSPIRANT STICK CONTAINING DIBENZYLIDENE ALDITOL 审中-公开
公开(公告)号：WO1996026709A3
公开(公告)日：1996-09-06
申请号：PCT/US1996002836
申请日：1996-02-29
申请人： THE GILLETTE COMPANY , VU, Tuan, M. , IOVANNI, Carl, F. , SANE, Jayant, N.
发明人： THE GILLETTE COMPANY
IPC分类号： A61K07/32

2. 发明申请

WO2004045514A2 MULTI-PORTION ANTIPERSPIRANT COMPOSITION 审中-公开
标题翻译：多部分抗菌组合物
公开(公告)号：WO2004045514A2
公开(公告)日：2004-06-03
申请号：PCT/US2003/036286
申请日：2003-11-13
申请人： THE GILLETTE COMPANY , ELLIOTT, David, L. , COLWELL, Dennis, J. , SANE, Jayant, N. , VU, Tuan, M. , GALANTE, Cheryl, Lynn
发明人： ELLIOTT, David, L. , COLWELL, Dennis, J. , SANE, Jayant, N. , VU, Tuan, M. , GALANTE, Cheryl, Lynn
IPC分类号： A61K
CPC分类号： A61K8/02 , A61K8/0229 , A61K8/0237 , A61K8/042 , A61K8/28 , A61K2800/262 , A61K2800/31 , A61Q15/00
摘要： Disclosed is a non-flowable anhydrous topical antiperspirant composition comprising a first portion and a second portion contiguous with the first portion. The first portion is semi-opaque to opaque and comprises a first hydrophobic carrier vehicle and a first gellant and has a particulate antiperspirant active suspended therein. The second portion is translucent to transparent and comprises a second hydrophobic carrier vehicle and a second gellant. Preferably, the second hydrophobic carrier vehicle has an average refractive index that approximately matches the refractive index of the second gellant. Ideally, for greater translucency the second portion will be substantially free of antiperspirant salt and/or other opacifying materials. Preferably, the first hydrophobic carrier vehicle also has an average refractive index that approximately matches the refractive index of the first gellant. Even more preferably, the second hydrophobic carrier vehicle and second gellant are comprised of substantially the same materials in substantially the same proportions as the first hydrophobic carrier vehicle and first gellant.
摘要翻译：公开了一种不可流动的无水局部止汗组合物，其包含与第一部分邻接的第一部分和第二部分。第一部分是不透明的，不透明的，并且包括第一疏水载体载体和第一胶凝剂，并且其中悬浮有颗粒止汗剂活性物质。第二部分是透明的，透明的，并且包括第二疏水载体载体和第二胶凝剂。优选地，第二疏水性载体载体具有与第二胶凝剂的折射率近似匹配的平均折射率。理想地，为了更大的半透明度，第二部分将基本上不含止汗盐和/或其它不透明的材料。优选地，第一疏水载体载体还具有与第一胶凝剂的折射率近似匹配的平均折射率。甚至更优选地，第二疏水载体载体和第二胶凝剂由与第一疏水载体载体和第一胶凝剂基本相同的比例的基本上相同的材料构成。

3. 发明申请

WO9626709A2 CLEAR ANTIPERSPIRANT STICK CONTAINING DIBENZYLIDENE ALDITOL 审中-公开
标题翻译：含有二苯基铝的透明防霉剂
公开(公告)号：WO9626709A2
公开(公告)日：1996-09-06
申请号：PCT/US9602836
申请日：1996-02-29
申请人： GILLETTE CO , VU TUAN M , IOVANNI CARL F , SANE JAYANT N
发明人： VU TUAN M , IOVANNI CARL F , SANE JAYANT N
IPC分类号： A61K8/00 , A61K8/02 , A61K8/04 , A61K8/20 , A61K8/26 , A61K8/28 , A61K8/34 , A61K8/368 , A61K8/41 , A61K8/49 , A61K8/73 , A61Q15/00 , A61K7/32
CPC分类号： A61K8/042 , A61K8/0229 , A61K8/26 , A61K8/28 , A61K8/345 , A61K8/498 , A61K8/731 , A61K2800/262 , A61K2800/51 , A61K2800/5422 , A61Q15/00
摘要： A clear gel cosmetic stick is disclosed which includes a liquid vehicle, an antiperspirant salt dissolved in the liquid vehicle, and a dibenzylidene alditol, and is further characterized in that said stick includes a hydroxyalkyl cellulose or a chelating agent or both a hydroxyalkyl cellulose and a chelating agent. The cosmetic stick comprises in percent by weight about 70 % to about 95 %, preferably 75 % to 92 %, of a liquid vehicle, about 1 % to about 22 %, preferably 3 % to 15 %, of an antiperspirant salt dissolved in said vehicle, about 0.5 % to about 3 %, preferably 0.5 % to 1.5 %, of a dibenzylidene alditol, about 0.1 % to about 0.5 %, preferably 0.2 % to 0.4 %, of a hydroxyalkyl cellulose, and about 0.05 % to about 3 %, preferably 0.1 % to 2 %, of a chelating agent. Preferably, the liquid vehicle comprises a polyhydric alcohol having from 3 to 6 carbon atoms and from 2 to 6 hydroxyl groups and is substantially free of monohydric alcohol and strong alkali such as sodium hydroxide and potassium hydroxide. Preferably, the cosmetic stick will have a pH greater than 4.4, more preferably greater than 4.7, a turbidity of less than about 120 NTU, more preferably less than 100 NTU, and a hardness of about 60 to 150. By lowering the dibenzylidene alditol level to 1.5 % or lower, the clarity and odor characteristics of the stick are greatly improved. The hardness of the stick is maintained by the addition of the hydroxyalkyl cellulose. The color of the stick is improved by the addition of the chelating agent.
摘要翻译：公开了一种透明的凝胶化妆棒，其包括液体载体，溶解在液体载体中的止汗盐和二亚苄基糖醇，其特征还在于所述棒包括羟烷基纤维素或螯合剂或羟烷基纤维素和螯合剂。化妆棒包含以重量百分比计约70％至约95％，优选75％至92％的液体载体，约1％至约22％，优选3％至15％的溶解在所述的防汗剂中的止汗盐约0.5％至约3％，优选0.5％至1.5％的二亚苄基糖醇，约0.1％至约0.5％，优选0.2％至0.4％的羟烷基纤维素，以及约0.05％至约3％，优选为0.1〜2％的螯合剂。优选地，液体载体包含具有3至6个碳原子和2至6个羟基的多元醇，并且基本上不含一元醇和强碱如氢氧化钠和氢氧化钾。优选地，化妆棒的pH值大于4.4，更优选大于4.7，浊度小于约120NTU，更优选小于100NTU，硬度为约60至150.通过降低二亚苄基胆固醇水平到1.5％以下，棒的透明度和气味特性大大提高。通过加入羟烷基纤维素来维持棒的硬度。通过添加螯合剂改善棒的颜色。

4. 发明申请

WO1998013015A1 CLEAR COSMETIC STICK COMPOSITION WITH ALKALI CHELATE 审中-公开
标题翻译：清洁化妆品组合物与阿尔卡利芝麻
公开(公告)号：WO1998013015A1
公开(公告)日：1998-04-02
申请号：PCT/US1997016339
申请日：1997-09-16
申请人： THE GILLETTE COMPANY , VU, Tuan, M. , SANE, Jayant, N. , COE, Craig, M.
发明人： THE GILLETTE COMPANY
IPC分类号： A61K07/32
CPC分类号： A61Q15/00 , A61K8/0229 , A61K8/361 , A61K2800/262 , A61K2800/51
摘要： Soap-based clear cosmetic sticks are disclosed which include an alkali metal salt of a chelating agent into the stick composition to increase the set temperature and the stick hardness and to prevent the formation of precipitates in the composition during aging. A typical composition of the present invention comprises about 40 to 90 %, preferably about 50 to 80 %, of a polyhydric alcohol, about 5 to 35 %, preferably 15 to 30 %, water, about 3 to 12 %, preferably 4 to 8 %, of an alkali metal salt of a C12-22, preferably C14-18, fatty acid, and about 0.3 to 1.6 %, preferably about 0.5 to 1.3 % of an alkali metal salt of a chelating agent, preferably a sodium or potassium salt of ethylene diamine tetraacetic acid (EDTA). The composition will also typically contain a cosmetic active ingredient such as a deodorant active. Preferably the composition will contain less than 0.3 %, most preferably less than 0.2 %, of C20-22 soap in order to achieve maximum clarity.
摘要翻译：公开了一种基于皂的透明化妆棒，其包括螯合剂的碱金属盐进入棒状组合物中以提高设定温度和棒状硬度，并防止在老化期间在组合物中形成析出物。本发明的典型组合物包含约40至90％，优选约50至80％的多元醇，约5至35％，优选15至30％的水，约3至12％，优选4至8 ％的C12-22的碱金属盐，优选C14-18，脂肪酸，和约0.3至1.6％，优选约0.5至1.3％的螯合剂的碱金属盐，优选钠或钾盐的乙二胺四乙酸（EDTA）。组合物还通常含有美容活性成分如除臭剂活性成分。优选地，组合物将含有小于0.3％，最优选小于0.2％的C20-22皂以实现最大的清晰度。

5. 发明申请

WO1996014052A1 METHOD OF MAKING POLYHYDRIC ALCOHOL SOLUTIONS OF ENHANCED EFFICACY ANTIPERSPIRANT ACTIVES 审中-公开
标题翻译：制备高效抗菌活性多糖醇溶液的方法
公开(公告)号：WO1996014052A1
公开(公告)日：1996-05-17
申请号：PCT/US1995014073
申请日：1995-10-30
申请人： THE GILLETTE COMPANY , PROVANCAL, Stephen, J. , CARRILLO, Angel, L. , FLUHLER, Thomas, J. , ORYSZCZAK, Richard , SANE, Jayant, N.
发明人： THE GILLETTE COMPANY
IPC分类号： A61K07/38
CPC分类号： A61Q15/00 , A61K8/26 , A61K8/28 , A61K8/345 , A61K8/44
摘要： The present invention comprises a process of preparing a solution of an enhanced efficacy aluminum antiperspirant salt in a polyhydric alcohol by (a) providing an aqueous solution consisting essentially of about 5 % to about 18 % by weight of an enhanced efficacy aluminum antiperspirant salt in water, the enhanced efficacy aluminum antiperspirant salt having been prepared in situ without having been dried to a solid powder; (b) mixing the aqueous solution with a sufficient amount of a liquid polyhydric alcohol to provide a mixed solution which has an antiperspirant salt to polyhydric alcohol ratio of about 1:4 to about 1.2:1; and (c) rapidly evaporating the water from the mixed solution under vacuum to provide a final liquid polyhydric alcohol solution containing about 20 to 50 % enhanced efficacy aluminum antiperspirant salt and about 2 to 16 % water, with the balance being polyhydric alcohol. An alkaline glycinate salt, such as sodium, potassium or zinc glycinate, may be added to the polyhydric alcohol prior to the addition of the antiperspirant salt solution in order to raise the pH of the recovered product to about 4.1 to 5.0.
摘要翻译：本发明包括通过（a）提供基本上由约5重量％至约18重量％的增强的功效铝止汗药盐在水中组成的水溶液来制备增强的功效性铝止汗药盐在多元醇中的溶液的方法已经在原位制备了不再干燥成固体粉末的增强效力的铝止汗盐; （b）将水溶液与足量的液体多元醇混合，得到具有止汗剂盐与多元醇比为约1:4至约1.2:1的混合溶液; 和（c）在真空下从混合溶液中快速蒸发水，得到含有约20至50％增强效力的铝止汗塞盐和约2至16％水的最终液体多元醇溶液，余量为多元醇。在加入止汗盐溶液之前，可以向多元醇中加入碱性甘氨酸盐，例如甘氨酸钠，钾或锌，以便将回收产物的pH提高至约4.1至5.0。

6. 发明申请

WO2004045514A3 MULTI-PORTION ANTIPERSPIRANT COMPOSITION 审中-公开
标题翻译：多部位抗刺激剂组合物
公开(公告)号：WO2004045514A3
公开(公告)日：2004-07-15
申请号：PCT/US0336286
申请日：2003-11-13
申请人： GILLETTE CO , ELLIOTT DAVID L , COLWELL DENNIS J , SANE JAYANT N , VU TUAN M , GALANTE CHERYL LYNN
发明人： ELLIOTT DAVID L , COLWELL DENNIS J , SANE JAYANT N , VU TUAN M , GALANTE CHERYL LYNN
IPC分类号： A61K8/02 , A61K8/28 , A61Q15/00 , A61K7/00 , A61K7/32 , A61K7/36 , A61K7/38
CPC分类号： A61K8/02 , A61K8/0229 , A61K8/0237 , A61K8/042 , A61K8/28 , A61K2800/262 , A61K2800/31 , A61Q15/00
摘要： Disclosed is a non-flowable anhydrous topical antiperspirant composition comprising a first portion and a second portion contiguous with the first portion. The first portion is semi-opaque to opaque and comprises a first hydrophobic carrier vehicle and a first gellant and has a particulate antiperspirant active suspended therein. The second portion is translucent to transparent and comprises a second hydrophobic carrier vehicle and a second gellant. Preferably, the second hydrophobic carrier vehicle has an average refractive index that approximately matches the refractive index of the second gellant. Ideally, for greater translucency the second portion will be substantially free of antiperspirant salt and/or other opacifying materials. Preferably, the first hydrophobic carrier vehicle also has an average refractive index that approximately matches the refractive index of the first gellant. Even more preferably, the second hydrophobic carrier vehicle and second gellant are comprised of substantially the same materials in substantially the same proportions as the first hydrophobic carrier vehicle and first gellant.
摘要翻译：公开了包含第一部分和与第一部分邻接的第二部分的非流动性无水局部止汗组合物。第一部分是半透明不透明的并且包含第一疏水性载体载体和第一胶凝剂并且具有悬浮于其中的颗粒状止汗剂活性物质。第二部分半透明至透明并且包含第二疏水性载体载体和第二胶凝剂。优选地，第二疏水性载剂具有与第二胶凝剂的折射率大致匹配的平均折射率。理想地，为了更大的半透明度，第二部分将基本上不含防汗剂盐和/或其他不透明材料。优选地，第一疏水性载体媒介物也具有与第一胶凝剂的折射率大致匹配的平均折射率。甚至更优选地，第二疏水载体媒介物和第二胶凝剂由与第一疏水性载体媒介物和第一胶凝剂基本上相同比例的基本上相同的材料构成。

7. 发明申请

WO1997014398A1 CLEAR COSMETIC STICK COMPOSITION WITH 2-METHYL-1,3-PROPANEDIOL 审中-公开
标题翻译：具有2-甲基-1,3-丙二醇的清晰化妆品组合物
公开(公告)号：WO1997014398A1
公开(公告)日：1997-04-24
申请号：PCT/US1996016375
申请日：1996-10-15
申请人： THE GILLETTE COMPANY , COE, Craig, M. , UTAEGBULAM, Chinyere, E., Onyekachi , JEAN, Yanick , VU, Tuan, M. , SANE, Jayant, N.
发明人： THE GILLETTE COMPANY
IPC分类号： A61K07/32
CPC分类号： A61Q15/00 , A61K8/0229 , A61K8/345 , A61K8/361 , A61K2800/262 , A61Q19/00
摘要： Soap-based clear cosmetic sticks are disclosed which include 2-methyl-1,3-propanediol in the composition to increase the set temperature, and also the stick hardness. A typical composition of the present invention comprises about 20 to 50 %, preferably 28 to 46 %, of 2-methyl-1,3-propanediol, about 3 to 12 %, preferably 4 to 8 %, of an alkali metal salt of a C12-22, preferably C14-18, fatty acid, about 10 to 42 %, preferably 18 to 30 %, of a polyhydric alcohol other than 2-methyl-1,3-propanediol, and about 5 to 35 %, preferably 15 to 30 %, water. To achieve the highest set temperature the composition should also contain an alkali metal salt, preferably a sodium or potassium salt, particularly an alkali metal halide such as sodium chloride or an alkali metal chelate such as di-, tri- or tetra-sodium EDTA. The composition will also typically contain a cosmetic active ingredient such as a deodorant active. Preferably the composition will contain less than 0.3 %, most preferably less than 0.2 %, of C20-22 soap in order to achieve maximum clarity.
摘要翻译：公开了在组合物中包含2-甲基-1,3-丙二醇的皂基透明化妆棒，以提高设定温度，以及粘度硬度。本发明的典型组合物包含约20至50％，优选28至46％的2-甲基-1,3-丙二醇，约3至12％，优选4至8％的碱金属盐优选C 14-18，优选C 14-18，脂肪酸，约10至42％，优选18至30％的除2-甲基-1,3-丙二醇以外的多元醇，以及约5至35％，优选15至 30％，水。为达到最高设定温度，组合物还应含有碱金属盐，优选钠盐或钾盐，特别是碱金属卤化物如氯化钠或碱金属螯合物，如二，三或四钠EDTA。组合物还通常含有美容活性成分如除臭剂活性成分。优选地，组合物将含有小于0.3％，最优选小于0.2％的C20-22皂以实现最大的清晰度。

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