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    • 7. 发明申请
    • MULTI-PORTION ANTIPERSPIRANT COMPOSITION
    • 多部位抗刺激剂组合物
    • WO2004045514A3
    • 2004-07-15
    • PCT/US0336286
    • 2003-11-13
    • GILLETTE COELLIOTT DAVID LCOLWELL DENNIS JSANE JAYANT NVU TUAN MGALANTE CHERYL LYNN
    • ELLIOTT DAVID LCOLWELL DENNIS JSANE JAYANT NVU TUAN MGALANTE CHERYL LYNN
    • A61K8/02A61K8/28A61Q15/00A61K7/00A61K7/32A61K7/36A61K7/38
    • A61K8/02A61K8/0229A61K8/0237A61K8/042A61K8/28A61K2800/262A61K2800/31A61Q15/00
    • Disclosed is a non-flowable anhydrous topical antiperspirant composition comprising a first portion and a second portion contiguous with the first portion. The first portion is semi-opaque to opaque and comprises a first hydrophobic carrier vehicle and a first gellant and has a particulate antiperspirant active suspended therein. The second portion is translucent to transparent and comprises a second hydrophobic carrier vehicle and a second gellant. Preferably, the second hydrophobic carrier vehicle has an average refractive index that approximately matches the refractive index of the second gellant. Ideally, for greater translucency the second portion will be substantially free of antiperspirant salt and/or other opacifying materials. Preferably, the first hydrophobic carrier vehicle also has an average refractive index that approximately matches the refractive index of the first gellant. Even more preferably, the second hydrophobic carrier vehicle and second gellant are comprised of substantially the same materials in substantially the same proportions as the first hydrophobic carrier vehicle and first gellant.
    • 公开了包含第一部分和与第一部分邻接的第二部分的非流动性无水局部止汗组合物。 第一部分是半透明不透明的并且包含第一疏水性载体载体和第一胶凝剂并且具有悬浮于其中的颗粒状止汗剂活性物质。 第二部分半透明至透明并且包含第二疏水性载体载体和第二胶凝剂。 优选地,第二疏水性载剂具有与第二胶凝剂的折射率大致匹配的平均折射率。 理想地,为了更大的半透明度,第二部分将基本上不含防汗剂盐和/或其他不透明材料。 优选地,第一疏水性载体媒介物也具有与第一胶凝剂的折射率大致匹配的平均折射率。 甚至更优选地,第二疏水载体媒介物和第二胶凝剂由与第一疏水性载体媒介物和第一胶凝剂基本上相同比例的基本上相同的材料构成。
    • 8. 发明申请
    • GENTLE-ACTING SKIN-DISINFECTANTS AND HYDROALCOHOLIC GEL FORMULATIONS
    • GENTLE-ACTING SKIN-DISINFANTANTS和HYDROALCOLOLIC GEL FORMULATIONS
    • WO03034994A3
    • 2003-07-17
    • PCT/US0233865
    • 2002-10-23
    • UNIV COLUMBIAMODAK SHANTAGAONKAR TRUPTI ACARAOS LAUSERSAMPATH LESTER
    • MODAK SHANTAGAONKAR TRUPTI ACARAOS LAUSERSAMPATH LESTER
    • A61K8/04A61K8/34A61K8/41A61K8/43A61K31/79A61Q17/00A61Q19/00A61K7/32A61K7/00A61K7/34A61K7/36A61K7/38
    • A61K8/042A61K8/347A61K8/416A61K8/43A61K31/79A61K2800/75A61Q17/005
    • Antimicrobial compositions having synergistic combinations of octoxyglycerin and at least one other antimicrobial agent in formulations which are more effective than prior art compositions without causing increased irritation to the skin of the average user. In certain embodiments, skin irritation may be minimized by low concentrations of antimicrobials and/or the presence of soothing compounds such as zinc. Preferred embodiments include combinations of octoxyglycerin, a quaternary compound, and at least one other antimicrobial agent. Without being bound to any particular theory, it is hypothesized that the unexpected antimicrobial effectiveness of combinations of octoxyglycerin may result from an enhancement of the permeability of microbes to antimicrobials caused by octoxyglycerin. Hydroalcoholic gel composition containing alcohol, water, hydrogel, and emollient or emulsifier, wherein the composition has a viscosity of below 2000 centipoises at between 20 and 40 DEG C. This skin-friendly hydroalcoholic gel composition, which can be further combined with silicone polymer, emollient solvent, thickening agent and antimicrobial agent, enhances rapid and long-term antimicrobial efficacy.
    • 在制剂中具有协同组合的辛氧基甘油和至少一种其它抗微生物剂的抗微生物组合物比现有技术组合物更有效,而不会对一般使用者的皮肤造成更大的刺激。 在某些实施方案中,皮肤刺激可以通过低浓度的抗微生物剂和/或舒缓化合物如锌的存在来最小化。 优选的实施方案包括辛氧基甘油,季化合物和至少一种其它抗微生物剂的组合。 不受任何特定理论的约束,假设辛氧基甘油组合的意想不到的抗菌效果可能是由于由辛氧基甘油引起的微生物对抗微生物剂的渗透性的提高。 含有醇,水,水凝胶和软化剂或乳化剂的水性醇凝胶组合物,其中该组合物在20至40℃之间的粘度低于2000厘泊。该皮肤友好的水醇凝胶组合物可进一步与硅氧烷聚合物组合, 润肤溶剂,增稠剂和抗菌剂,可提高快速和长期的抗菌功效。
    • 10. 发明申请
    • DEODORANT
    • 除臭剂
    • WO01012145A1
    • 2001-02-22
    • PCT/EP2000/007624
    • 2000-08-04
    • A61L9/01A61K7/36
    • A61L9/01
    • An agent with a deodorizing effect containing (a) one or more metal salts of an unbranched or branched, unsaturated or saturated mono- or multihydroxylated acid with at least 16 carbon atoms, and/or resin acid with the exception of alkali metal salts; (b) one or more solubilizers, (c) up to 30 % by weight of one or more organic solvents soluble in water and (d) water. The agent forms, with a spray dispenser, a product which is used to deodorize objects, surfaces or spaces. It can be used as a concentrate and can be produced from a concentrate.
    • 具有除臭效果(A)含有具有至少16个碳原子和/或用碱金属盐以外的树脂酸的直链或支链的,不饱和的或饱和的,单或多羟基化的脂肪酸的一种或多种金属的盐,(b)一种或多种增溶剂甲手段, (c)至多30重量%的一种或多种水溶性有机溶剂,和(d)水的%,连同一种喷射分配器中,可以使用一个产品,一个在一个方法的除臭用于除臭的物体,表面或空间 使用对象,一个表面或空间,以及使用作为浓缩物和产生的浓缩物。