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1. 发明申请

WO2007050143A2 SURFACE MODIFICATION IN A MANIPULATION CHAMBER 审中-公开
标题翻译：操纵室中的表面修饰
公开(公告)号：WO2007050143A2
公开(公告)日：2007-05-03
申请号：PCT/US2006/022959
申请日：2006-06-13
申请人： APPLERA CORPORATION , LAU, Aldrich, N., K. , PHAN, Huan, L.
发明人： LAU, Aldrich, N., K. , PHAN, Huan, L.
IPC分类号： C07K1/26 , G01N27/00
CPC分类号： G01N27/305 , B03C11/00 , C07K1/26
摘要： A device for manipulating biological material, the device including at least one electrode and a photoconductive material configured to receive the biological material; and a light source configured to illuminate the photoconductive material so as to modulate an electric field, wherein the electric field is configured to manipulate the biological material; wherein a surface of the at least one electrode and/or the photoconductive material is modified with at least one of a carboxylic moiety, an amino moiety, a poly(ethylene glycol) moiety, a polymer of (poly(ethylene oxide) methyl ether) acrylate, a poly(2-hydroxyethyl (meth)acrylate), a poly(N-vinylpyrrolidone), a poly(N-vinylformamide), a poly(N-vinylformamide) derivative, a poly((meth)acrylamide), and a poly((meth)acrylamide) derivative. Methods for manipulating biological material are also disclosed.
摘要翻译：一种用于操纵生物材料的装置，该装置包括至少一个电极和被配置为容纳生物材料的光导材料; 以及光源，被配置为照亮所述光电导材料以调制电场，其中所述电场被配置为操纵所述生物材料; 其中所述至少一个电极和/或光电导材料的表面用羧基部分，氨基部分，聚（乙二醇）部分，（聚（环氧乙烷）甲基醚）的聚合物，丙烯酸酯，聚（甲基）丙烯酸2-羟乙酯），聚（N-乙烯基吡咯烷酮），聚（N-乙烯基甲酰胺），聚（N-乙烯基甲酰胺）衍生物，聚（（甲基）丙烯酰胺）聚（（甲基）丙烯酰胺）衍生物。还公开了用于操作生物材料的方法。

2. 发明申请

WO2003084629A3 METHODS AND APPARATUS FOR SEPARATION AND ISOLATION OF COMPONENTS FROM A BIOLOGICAL SAMPLE 审中-公开
公开(公告)号：WO2003084629A3
公开(公告)日：2003-10-16
申请号：PCT/US2003/009628
申请日：2003-03-27
申请人： CALIPER TECHNOLOGIES CORP. , DUBROW, Robert, S. , BOUSSE, Luc, J. , PHAN, Huan, L.
发明人： DUBROW, Robert, S. , BOUSSE, Luc, J. , PHAN, Huan, L.
IPC分类号： G01N33/558
摘要： Devices, systems and methods for use in separating sample materials into different sample components and then isolating one or more of the sample components for further processing or analysis are disclosed. Devices employ configurations that optionally allow a sample material to be electrophoretically separated into sample components in a separation matrix within a separation conduit. The sample components may then be detected in a detection zone in the separation conduit and then selected components shunted to a component collection conduit within the device downstream of the detection zone for further processing or analysis based on information received at the detection zone. Methods of using these devices, and systems that incorporate these devices are also envisioned.

3. 发明申请

WO03084629A2 METHODS, SYSTEMS AND APPARATUS FOR SEPARATION AND ISOLATION OF ONE OR MORE SAMPLE COMPONENTS OF A SAMPLE BIOLOGICAL MATERIAL 审中-公开
标题翻译：用于分离和分离样品生物材料的一个或多个样品组分的方法，系统和装置
公开(公告)号：WO03084629A2
公开(公告)日：2003-10-16
申请号：PCT/US0309628
申请日：2003-03-27
申请人： CALIPER TECHN CORP , DUBROW ROBERT S , BOUSSE LUC J , PHAN HUAN L
发明人： DUBROW ROBERT S , BOUSSE LUC J , PHAN HUAN L
IPC分类号： B01L3/00 , G01N27/447 , B01D
CPC分类号： B01L3/50273 , B01L3/502715 , B01L3/502753 , B01L3/502784 , B01L2200/0605 , B01L2200/0631 , B01L2200/10 , B01L2300/0816 , B01L2400/0421 , B01L2400/0487 , G01N27/44791 , Y10T436/25
摘要： Devices, systems and methods for use in separating sample materials into different sample components and then isolating one or more of the sample components for further processing or analysis are disclosed. Devices employ configurations that optionally allow a sample material to be electrophoretically separated into sample components in a separation matrix within a separation conduit. The sample components may then be detected in a detection zone in the separation conduit and then selected components shunted to a component collection conduit within the device downstream of the detection zone for further processing or analysis based on information received at the detection zone. Methods of using these devices, and systems that incorporate these devices are also envisioned.
摘要翻译：公开了用于将样品材料分离成不同样品组分，然后分离一个或多个样品组分用于进一步处理或分析的装置，系统和方法。设备采用可选地允许样品材料在分离管道内的分离基质中电泳分离成样品组分的构型。然后可以在分离管道中的检测区域中检测样品组分，然后根据在检测区域接收的信息，将检测区域下游的选定部件分流到设备下游的组件收集管道，以进一步处理或分析。也可以设想使用这些装置的方法，以及并入这些装置的系统。

4. 发明申请

WO2007050143A3 SURFACE MODIFICATION IN A MANIPULATION CHAMBER 审中-公开
标题翻译：操纵室中的表面修饰
公开(公告)号：WO2007050143A3
公开(公告)日：2009-05-14
申请号：PCT/US2006022959
申请日：2006-06-13
申请人： APPLERA CORP , LAU ALDRICH N K , PHAN HUAN L
发明人： LAU ALDRICH N K , PHAN HUAN L
IPC分类号： C12M1/34 , C12M3/00
CPC分类号： G01N27/305 , B03C11/00 , C07K1/26
摘要： A device for manipulating biological material, the device including at least one electrode and a photoconductive material configured to receive the biological material; and a light source configured to illuminate the photoconductive material so as to modulate an electric field, wherein the electric field is configured to manipulate the biological material; wherein a surface of the at least one electrode and/or the photoconductive material is modified with at least one of a carboxylic moiety, an amino moiety, a poly(ethylene glycol) moiety, a polymer of (poly(ethylene oxide) methyl ether) acrylate, a poly(2-hydroxyethyl (meth)acrylate), a poly(N-vinylpyrrolidone), a poly(N-vinylformamide), a poly(N-vinylformamide) derivative, a poly((meth)acrylamide), and a poly((meth)acrylamide) derivative. Methods for manipulating biological material are also disclosed.
摘要翻译：一种用于操纵生物材料的装置，该装置包括至少一个电极和被配置为容纳生物材料的光导材料; 以及光源，被配置为照亮所述光电导材料以调制电场，其中所述电场被配置为操纵所述生物材料; 其中所述至少一个电极和/或光电导材料的表面用羧基部分，氨基部分，聚（乙二醇）部分，（聚（环氧乙烷）甲基醚）的聚合物，丙烯酸酯，聚（甲基）丙烯酸2-羟乙酯），聚（N-乙烯基吡咯烷酮），聚（N-乙烯基甲酰胺），聚（N-乙烯基甲酰胺）衍生物，聚（（甲基）丙烯酰胺）聚（（甲基）丙烯酰胺）衍生物。还公开了用于操作生物材料的方法。

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