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    • 5. 发明申请
    • METHOD OF PROCESSING MASS SPECTROMETRY DATA
    • 处理质谱数据的方法
    • WO2006058198A2
    • 2006-06-01
    • PCT/US2005/042714
    • 2005-11-23
    • THERMO FINNIGAN LLCLANGE, OliverSENKO, Michael, W.
    • LANGE, OliverSENKO, Michael, W.
    • G06K9/00H01J49/38
    • H01J49/38G06K9/00523H01J49/0036
    • A method of processing Fourier Transform Mass Spectrometry (FTMS) data comprises carrying out a Fourier Transform of a part of a time domain transient and identifying from that transformed data signal peaks representative of the presence of ions. Once the peaks have been identified, the full transient is then transformed, and the peaks identified in the partial transient transform are used to locate true peaks in the transformed full transient. The number of 'false' peaks resulting from random noise has been found to correlate to the resolution, so that using a partial transient to identify true peaks reduces the risk of false peaks being included; nevertheless this information can then be applied to the full data set when transformed. As an alternative, different parts of the full data set can be transformed and then correlated; because any noise will be random, false peaks should occur at different places in the two partial transforms.
    • 处理傅立叶变换质谱(FTMS)数据的方法包括执行时域瞬态的一部分的傅立叶变换并且从该变换的数据信号中识别表示离子的存在的峰。 一旦峰已被识别,完整的瞬态被转换,并且在部分瞬态转换中识别的峰被用于在转换的全瞬态中定位真正的峰。 已发现由随机噪声产生的“假”峰的数量与分辨率相关,因此使用部分瞬态来识别真实峰值会降低包括假峰值的风险; 然而这些信息可以在转换后应用于整个数据集。 作为一种选择,整个数据集的不同部分可以被转换并相互关联; 因为任何噪声都是随机的,所以在两次部分变换中的不同位置应该出现假峰。
    • 7. 发明申请
    • METHOD AND APPARATUS FOR MASS SPECTROMETRY
    • 用于质谱分析的方法和设备
    • WO2005031290A2
    • 2005-04-07
    • PCT/EP2004/010735
    • 2004-09-24
    • THERMO FINNIGAN LLCMALEK, RobertPESCH, ReinholdHORNING, StevanLANGE, Oliver
    • MALEK, RobertPESCH, ReinholdHORNING, StevanLANGE, Oliver
    • G01J3/00
    • H01J49/0027
    • The present invention relates to mass spectrometry and, more particularly, to the scheduling of the steps involved in performing mass spectrometry. The present invention will be of particular benefit to types of mass spectrometry that generate large quantities of data and hence give rise to lengthy data-processing. The present invention provides a method of mass spectrometry comprising a plurality of cycles, each cycle comprising the steps of (a) preparing ions to be analysed by a mass spectrometer; (b) using a detector of the mass spectrometer to collect data from the ions prepared in step (a); and (c) processing the data collected in step (b) with processing means; wherein at least a part of step (a) and/or a part of step (b) of a cycle is performed concurrently with part (c) of a previous cycle.
    • 本发明涉及质谱法,并且更具体地涉及执行质谱法中涉及的步骤的调度。 本发明将对产生大量数据并因此引起冗长的数据处理的质谱仪类型特别有益。 本发明提供一种包括多个循环的质谱法,每个循环包括以下步骤:(a)制备待由质谱仪分析的离子; (b)使用质谱仪的检测器从步骤(a)中制备的离子收集数据; 和(c)用处理装置处理步骤(b)中收集的数据; 其中周期的步骤(a)的至少一部分和/或步骤(b)的一部分与前一周期的部分(c)同时执行。