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    • 3. 发明申请
    • A METHOD OF IMPROVING A MASS SPECTRUM
    • 改进质谱的方法
    • WO2005093782A2
    • 2005-10-06
    • PCT/EP2005/003367
    • 2005-03-24
    • THERMO FINNIGAN LLCHORNING, Stevan, RoyLANGE, OliverMALEK, RobertWIEGHAUS, Andreas
    • HORNING, Stevan, RoyLANGE, OliverMALEK, RobertWIEGHAUS, Andreas
    • H01J49/00
    • H01J49/38H01J49/0009
    • The present invention provides a method of improving a mass spectrum collected from a mass spectrometer comprising a detector for collecting a mass spectrum from ions stored in or released from an ion trapping volume, wherein assignment of masses to peaks appearing in the mass spectrum is sensitive to an experimental parameter related to the mass spectrometer or the operation thereof, such as ion abundance, the method comprising: determining a positional value of a peak; determining the experimental parameter associated with the mass spectrum; comparing the determined positional value with positional values of peaks contained in a calibration dataset; and improving the determined positional value of the peak from adjacent peak positional values by interpolation thereby to provide a corrected mass assignment for the peak. The present invention also provides a method of calibrating such a mass spectrometer.
    • 本发明提供了一种改进从质谱仪收集的质谱的方法,该质谱仪包括用于从离子捕获体积存储或释放的离子中收集质谱的检测器,其中质谱对质谱中出现的峰的分配对 与质谱仪或其操作相关的实验参数,例如离子丰度,该方法包括:确定峰的位置值; 确定与质谱相关的实验参数; 将确定的位置值与校准数据集中包含的峰的位置值进行比较; 并且通过内插从相邻的峰值位置值改善确定的峰值的位置值,从而为峰值提供校正的质量分配。 本发明还提供了一种校准这种质谱仪的方法。
    • 5. 发明申请
    • METHOD OF PROCESSING AND STORING MASS SPECTROMETRY DATA
    • 处理和存储大量光谱数据的方法
    • WO2005031791A2
    • 2005-04-07
    • PCT/EP2004/010736
    • 2004-09-23
    • THERMO FINNIGAN LLCMALEK, RobertLANGE, Oliver
    • MALEK, RobertLANGE, Oliver
    • H01J49/00
    • H01J49/0036H03M7/30
    • A data compression technique is disclosed for Fourier Transform Mass Spectrometry (FTMS). A statistical analysis is applied to the data in the frequency domain since most of this data is a result of randomly distributed electronic noise. A fit of the whole frequency dataset to the distribution is made to determine preliminary moments of the distribution. The data in the tail of that distribution (which is mainly the peak data) is then removed and the remaining data points are re-fitted to the distribution, to identify the moments of distribution of that remaining noise data. A noise threshold for the mass spectrum is then applied using the calculated moments. The data above the threshold is kept. The whole spectrum can be reconstituted by storing the moments of distribution along with the peak data and then regenerating the noise from those moments and adding it to the peak data.
    • 公开了用于傅里叶变换质谱(FTMS)的数据压缩技术。 对频域中的数据进行统计分析,因为这些数据大部分是随机分布的电子噪声的结果。 将整个频率数据集合到分布上进行确定分布的初步时刻。 然后删除该分布尾部的数据(主要是峰值数据),并将剩余的数据点重新拟合到分布中,以识别该剩余噪声数据的分布时刻。 然后使用计算的时刻应用质谱的噪声阈值。 保持阈值以上的数据。 可以通过将分布的时刻与峰值数据一起存储,然后从那些时刻再生噪声并将其加到峰值数据来重构整个频谱。
    • 8. 发明申请
    • DEVICE AND METHOD FOR EVALUATING A SIGNAL INDICATIVE OF THE RESPIRATION OF A PERSON
    • 用于评估表示个人呼吸的信号的装置和方法
    • WO2006045559A1
    • 2006-05-04
    • PCT/EP2005/011358
    • 2005-10-21
    • MAP MEDIZIN-TECHNOLOGIE GMBHSCHÄTZL, StefanMEIER, JörgDANA-MIKA, AleksandraBETZL, ThomasLANGE, Oliver
    • SCHÄTZL, StefanMEIER, JörgDANA-MIKA, AleksandraBETZL, ThomasLANGE, Oliver
    • A61B5/087
    • A61B5/4818A61B5/087
    • The present invention relates to a device and a method for evaluating a signal that is indicative of the respiration of a person. A signal evaluation of this kind is particularly suitable for examining a patient with respect to the occurrence of sleep-related breathing disturbances. It is the object of the present invention to provide a device and a method by means of which phases and properties which are relevant to the control and diagnosis, in particular respiratory patterns in the temporal course of the respiration of a patient, can be detected with a sufficiently high reliability. In view of the device, this object is achieved in accordance with the present invention by means of a device for evaluating a signal that is indicative of the temporal course of the respiration of a patient, in particular a respiratory flow signal, by means of an electronic evaluation means which is configured in such a manner that it evaluates the signal by continuously generating intermediate evaluation results for short signal periods and for longer signal periods being parallel thereto and performs an identification of respiratory patterns in the time signal or in specific time periods on the basis of the position of the intermediate evaluation results of the short signal periods relative to the intermediate evaluation results of the longer signal periods.
    • 本发明涉及一种用于评估指示人的呼吸的信号的装置和方法。 这种信号评估特别适合于对睡眠相关呼吸障碍的发生进行检查。 本发明的目的是提供一种装置和方法,通过该装置和方法可以检测与患者的呼吸的时间过程中的控制和诊断特别是呼吸模式相关的相位和性质, 足够高的可靠性。 鉴于该装置,根据本发明,通过用于评估指示患者的呼吸的时间进程(特别是呼吸流动信号)的信号的装置,借助于该装置来实现该目的,该目的是通过 电子评估装置,其被配置为通过连续生成用于短信号周期的中间评估结果和与其并行的较长信号周期来评估信号,并且在时间信号中或在特定时间段内执行呼吸模式的识别 相对于较长信号周期的中间评价结果,短信号周期的中间评价结果的位置的基础。
    • 9. 发明申请
    • ZUGFEDERKLEMME MIT ZUEINANDER SPIEGELBILDLICHEN ZUGFEDERN
    • 相互镜像避免拉拔拉簧
    • WO2004047226A1
    • 2004-06-03
    • PCT/EP2003/012580
    • 2003-11-11
    • PHOENIX CONTACT GMBH & CO.LANGE, Oliver
    • LANGE, Oliver
    • H01R4/48
    • H01R4/4827H01R4/4845
    • Eine solche Zugfederklemme hat schlaufenförmig ausgebildete Zugfedern mit einem Anlageschenkel zur Kontaktierung eines Strombalkens und mit einem Feder- und Klemmschenkel, wobei letzterer zur Ausbildung der Klemmschenkel durch ein Klemmfenster durchbrochen ist. Mittels eines Betätigungselementes, in das eine Werkzeugklinge in Eingriff bringbar ist, sind die Federschenkel der Zugfedern mit Druck beaufschlagbar, um die Klemmfenster zu öffnen. Dieses Betätigungselement befindet sich zwischen den beiden einander gegenüberliegenden Federschenkeln der Zugfeder. Um eine zeitsparendere Betätigung zu ermöglichen, liegt in der Beaufschlagungslage das Betätigungselement zugleich an beiden Federschenkeln an. So hat das Betätigungselement an seinen einander gegenüberliegenden Aussenseiten Anlagestellen, deren Abstand sich in der einen Bewegungsrichtung des Betätigungselementes vergrössert und sich in der anderen Bewegungsrichtung verkleinert.
    • 这样的拉伸弹簧与接触腿的环形弹簧用于功率波束接触并与弹簧和夹持腿,后者被刺穿以形成通过夹紧窗口夹紧腿。 通过在其中一个工具刀片可被带入接合的致动器的装置,所述拉伸弹簧的弹簧腿可以被加压以打开夹紧窗口。 这个致动元件位于所述拉伸弹簧的两个相对的弹簧臂之间。 为了能够节省时间的操作中,致动元件位于Beaufschlagungslage同时到两个弹簧腿。 因此,在它的相对的外侧上邻接点其距离在致动元件的运动的方向的放大图,并在运动的其他方向上减小所述操作构件。