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    • 6. 发明申请
    • LOCKING MECHANISMS FOR FIXATION DEVICES AND METHODS OF ENGAGING TISSUE
    • 用于固定装置的锁定机构和接合组织的方法
    • WO2005112792A3
    • 2006-03-23
    • PCT/US2005017178
    • 2005-05-16
    • EVALVE INCGOLDFARB ERIC ASARABIA JAIME ERASCHDORF ALFRED HMADDEN JOHN P
    • GOLDFARB ERIC ASARABIA JAIME ERASCHDORF ALFRED HMADDEN JOHN P
    • A61B17/00A61B17/04A61B17/08A61B17/10A61B17/28
    • A61B17/08A61B17/00234A61B17/10A61B17/122A61B17/1285A61B17/2909A61B2017/00243A61B2017/00783A61B2017/2946A61F2/2442
    • Devices, systems and methods are provided for tissue approximation and repair at treatment sites. In particular, fixation devices are provided comprising a pair of fixation elements each having a first end, a free end opposite the first end, and an engagement surface therebetween for engaging the tissue, the first ends being movably coupled together such that the fixation elements are moveable between an open position wherein the free ends are spaced apart and a closed position wherein the free ends are closer together with the engagement surfaces generally facing each other. The fixation devices also include a locking mechanism coupled to the fixation elements for locking the fixation elements in place. The devices, systems and methods of the invention will find use in a variety of therapeutic procedures, including endovascular, minimally-invasive, and open surgical procedures, and can be used in various anatomical regions, including the abdomen, thorax, cardiovascular system, heart, intestinal tract, stomach, urinary tract, bladder, lung, and other organs, vessels, and tissues. The invention is particularly useful in those procedures requiring minimally-invasive or endovascular access to remote tissue locations, where the instruments utilized must negotiate long, narrow, and tortuous pathways to the treatment site.
    • 提供设备,系统和方法用于组织近似和修复治疗部位。 特别地,提供了固定装置,其包括一对固定元件,每个固定元件具有第一端,与第一端相对的自由端和用于接合组织的接合表面,第一端可移动地联接在一起,使得固定元件 在其中自由端间隔开的打开位置和闭合位置之间可移动,其中自由端通常彼此面对的接合表面更靠近在一起。 固定装置还包括联接到固定元件的锁定机构,用于将固定元件锁定就位。 本发明的装置,系统和方法将用于各种治疗方法,包括血管内,微创和开放性外科手术,并可用于各种解剖学领域,包括腹部,胸部,心血管系统,心脏 ,肠道,胃,尿道,膀胱,肺和其他器官,血管和组织。 本发明在需要微创或血管内进入远程组织位置的那些程序中特别有用,其中所使用的仪器必须协商到治疗部位的长,窄和曲折的路径。
    • 7. 发明申请
    • LOCKING MECHANISMS FOR FIXATION DEVICES AND METHODS OF ENGAGING TISSUE
    • 用于固定装置的锁定机构和接合组织的方法
    • WO2005112792A2
    • 2005-12-01
    • PCT/US2005/017178
    • 2005-05-16
    • EVALVE, INC.GOLDFARB, Eric, A.SARABIA, Jaime, E.RASCHDORF, Alfred, H.MADDEN, John, P.
    • GOLDFARB, Eric, A.SARABIA, Jaime, E.RASCHDORF, Alfred, H.MADDEN, John, P.
    • A61B17/10
    • A61B17/08A61B17/00234A61B17/10A61B17/122A61B17/1285A61B17/2909A61B2017/00243A61B2017/00783A61B2017/2946A61F2/2442
    • Devices, systems and methods are provided for tissue approximation and repair at treatment sites. In particular, fixation devices are provided comprising a pair of fixation elements each having a first end, a free end opposite the first end, and an engagement surface therebetween for engaging the tissue, the first ends being movably coupled together such that the fixation elements are moveable between an open position wherein the free ends are spaced apart and a closed position wherein the free ends are closer together with the engagement surfaces generally facing each other. The fixation devices also include a locking mechanism coupled to the fixation elements for locking the fixation elements in place. The devices, systems and methods of the invention will find use in a variety of therapeutic procedures, including endovascular, minimally-invasive, and open surgical procedures, and can be used in various anatomical regions, including the abdomen, thorax, cardiovascular system, heart, intestinal tract, stomach, urinary tract, bladder, lung, and other organs, vessels, and tissues. The invention is particularly useful in those procedures requiring minimally-invasive or endovascular access to remote tissue locations, where the instruments utilized must negotiate long, narrow, and tortuous pathways to the treatment site.
    • 提供了设备,系统和方法用于治疗部位的组织近似和修复。 特别地,提供固定装置,其包括一对固定元件,每个固定元件具有第一端,与第一端相对的自由端以及用于接合组织的接合表面,第一端可移动地联接在一起,使得固定元件 在其中自由端间隔开的打开位置和闭合位置之间可移动,其中自由端与通常彼此面对的接合表面更靠近在一起。 固定装置还包括联接到固定元件的锁定机构,用于将固定元件锁定就位。 本发明的装置,系统和方法将用于各种治疗方法,包括血管内,微创和开放手术,并可用于各种解剖区域,包括腹部,胸部,心血管系统,心脏 ,肠道,胃,尿道,膀胱,肺和其他器官,血管和组织。 本发明在需要微创或血管内进入远程组织位置的那些程序中特别有用,其中所使用的仪器必须协商到治疗部位的长,窄和曲折的路径。
    • 10. 发明申请
    • APPARATUS FOR TREATING DISORDERS OF THE SINUSES
    • 用于治疗神经病变的装置
    • WO2012039906A1
    • 2012-03-29
    • PCT/US2011/049929
    • 2011-08-31
    • ACCLARENT, INC.GOLDFARB, Eric, A.CHOW, Mina, W.b.WHITE, John, W.CHANG, John, Y.PADER, Mei, Y.LIBERATORE, Jessica, M.TANTISIRA, RaditLOH, Serena, SweiMAKOWER, JoshuaVO, HungGANDIONCO, Isidro, M.GOTTESMAN, Michael, J.
    • GOLDFARB, Eric, A.CHOW, Mina, W.b.WHITE, John, W.CHANG, John, Y.PADER, Mei, Y.LIBERATORE, Jessica, M.TANTISIRA, RaditLOH, Serena, SweiMAKOWER, JoshuaVO, HungGANDIONCO, Isidro, M.GOTTESMAN, Michael, J.
    • A61B1/233A61B17/24
    • A61B17/24A61B1/00147A61B17/320016A61B17/3207A61B2017/00331A61B2017/22042A61B2017/22069A61M25/0113A61M25/09041A61M29/02A61M2025/0681A61M2025/09125
    • A medical device for the treatment of a sinus opening includes a handle, a grooming sheath, a rail, a guide wire, a balloon catheter and a balloon catheter movement mechanism. The handle has a proximal end, a distal end and a longitudinal axis along the length of the handle. The grooming sheath has a distal end and a proximal end with the proximal end of the grooming sheath being attached to the distal end of the handle. The rail has a distal end and a proximal end and disposed partially within the grooming sheath to define an annular lumen is between the rail and the grooming sheath. The guide wire operatively extends from the distal end of the rail and the balloon catheter is disposed at least partially in the handle and annular lumen. The balloon catheter movement mechanism operatively disposed on the handle and configured for advancement and retraction of the balloon catheter through both the handle and the annular lumen and along both the rail and guide wire by user operation of the balloon catheter movement mechanism. A method for treating a sinus opening includes inserting a medical device for the treatment of a sinus opening partially into a patient's anatomy and then positioning a guide wire operatively extending from a rail of a medical device into a sinus opening of the patient. The method further includes advancing a balloon catheter from an annular lumen of the medical device and along both the rail of the medical device and the guide wire. The method also includes treating the sinus opening via inflation of the balloon catheter. In the method, the annular lumen is between the rail and a grooming sheath of the medical device and the advancing is accomplished via user operation of a balloon catheter movement mechanism of the medical device.
    • 用于治疗窦口的医疗装置包括手柄,梳理护套,轨道,导丝,球囊导管和气囊导管移动机构。 手柄具有沿手柄长度的近端,远端和纵向轴线。 修饰鞘具有远端和近端,其中修饰护套的近端附接到手柄的远端。 轨道具有远端和近端并且部分地设置在梳理护套内以限定在轨道和修饰鞘之间的环形腔。 引导线从轨道的远端可操作地延伸,并且球囊导管至少部分地设置在手柄和环形腔中。 气囊导管移动机构可操作地设置在手柄上并且被配置用于通过球囊导管移动机构的用户操作通过手柄和环形内腔以及沿导轨和引导线的前进和缩回。 用于治疗窦口的方法包括将用于治疗窦开口的医疗装置部分地插入患者的解剖结构中,然后将从医疗装置的轨道可操作地延伸的导丝定位到患者的窦口中。 该方法还包括从医疗装置的环形腔并且沿医疗装置的导轨和引导线推进气囊导管。 该方法还包括通过气囊导管的膨胀来治疗窦口。 在该方法中,环形腔位于轨道和医疗装置的整洁护套之间,并且通过用户操作医疗装置的气囊导管移动机构来实现前进。