专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO0059373A9 ASSAY DEVICE FOR MEASURING CHARACTERISTICS OF A FLUID ON A CONTINUAL BASIS 审中-公开
标题翻译：用于测量流体在连续基础上的特性的测定装置
公开(公告)号：WO0059373A9
公开(公告)日：2002-02-07
申请号：PCT/US0009393
申请日：2000-04-07
申请人： SPECTRX INC , KUMAR KRISHNA S , PAPP JOSEPH , FARQUHAR J DAVID , TAYLOR LANCE , SMITH ALAN M , VREEKE MARK S , HATCH MICHAEL R , SCHIFFER JARAD , FAUPEL MARK L , CONNOLLY JAMES
发明人： KUMAR KRISHNA S , PAPP JOSEPH , FARQUHAR J DAVID , TAYLOR LANCE , SMITH ALAN M , VREEKE MARK S , HATCH MICHAEL R , SCHIFFER JARAD , FAUPEL MARK L , CONNOLLY JAMES
IPC分类号： G01N33/66 , A61B5/00 , G01N27/28 , G01N27/416
CPC分类号： A61B5/1486 , A61B5/1495
摘要： The present invention is directed at an assay device for detecting and enabling measurement of an analyte in a fluid. The assay device contains: a) an inlet port to receive fluid; b) a well in fluid communication with the inlet port; c) an outlet port in fluid communication with the well, wherein the outlet port is designed to allow discharge of the fluid; d) at least one first working electrode and at least one reference electrode disposed within the well; e) a quantity of reactant that reacts with the analyte to form a reaction product, wherein the reaction product is in fluid communication with the at least one first working electrode; and f) at least one membrane disposed over or around the reactant to regulate contact of the analyte in the fluid with the reactant.
摘要翻译：本发明涉及用于检测和测量流体中分析物的测定装置。测定装置包含：a）用于接收流体的入口; b）与入口流体连通的井; c）与所述井流体连通的出口，其中所述出口被设计成允许流体排放; d）至少一个第一工作电极和设置在所述阱内的至少一个参考电极; e）一定量的与分析物反应以形成反应产物的反应物，其中反应产物与至少一个第一工作电极流体连通; 和f）设置在反应物上方或周围的至少一个膜，以调节流体中分析物与反应物的接触。

2. 发明申请

WO2010021898A1 METHOD AND APPARATUS FOR DISEASE DIAGNOSIS AND SCREENING USING EXTREMELY LOW FREQUENCY ELECTROMAGNETIC FIELDS 审中-公开
标题翻译：使用极低频电磁场进行疾病诊断和筛选的方法和装置
公开(公告)号：WO2010021898A1
公开(公告)日：2010-02-25
申请号：PCT/US2009/053669
申请日：2009-08-13
申请人： FAUPEL, Mark, L.
发明人： FAUPEL, Mark, L.
IPC分类号： A61B5/04
CPC分类号： A61B5/04 , A61B5/7264 , A61B2562/0209 , A61B2562/046 , G06F19/00
摘要： Novel methods and apparatus for diagnosing or screening disease states in living organisms by the measurement and analysis of extremely low frequency electromagnetic fields, particularly extremely low frequency alternating current. The measurement of such fields is performed at a single point or at several test points on or in the body and compared to one or more reference. Information in the time-varying electromagnetic field is collected, then processed by diagnostic or screening algorithms to provide information about the disease state of the tissue being assessed.
摘要翻译：用于通过测量和分析极低频电磁场，特别是极低频交流电来诊断或筛选活体中疾病状态的新方法和装置。这些场的测量在单个点或身体上或身体上的几个测试点进行，并与一个或多个参考相比较。收集时变电磁场中的信息，然后通过诊断或筛选算法进行处理，以提供有关待评估组织的疾病状态的信息。

3. 发明申请

WO02071026A9 SYSTEM AND METHOD FOR DETERMINING TISSUE CHARACTERISTICS 审中-公开
标题翻译：用于确定组织特征的系统和方法
公开(公告)号：WO02071026A9
公开(公告)日：2003-02-06
申请号：PCT/US0206350
申请日：2002-03-01
申请人： SPECTRX INC , BAMBOT SHABBIR , FAUPEL MARK L , AGRAWAL ANANT , IGNOTZ KEITH D , FORDHAM ANDREW
发明人： BAMBOT SHABBIR , FAUPEL MARK L , AGRAWAL ANANT , IGNOTZ KEITH D , FORDHAM ANDREW
IPC分类号： A61B5/00 , A61B5/103 , G01N
CPC分类号： A61B5/4331 , A61B5/0071 , A61B5/0075 , A61B5/0084 , A61B5/444
摘要： The present invention, according to its various embodiments, provides for a method and apparatus that interrogates, receives and analyzes full emission spectra for at least one fluorescence excitation wavelength and for at least one reflectance measurement to determine tissue characteristics. According to embodiments, the method of the present invention comprises of illuminating a first portion of a target tissue with optical energy, forming a first image of the target tissue, illuminating a second portion of the target tissue with optical energy, performing spectroscopic measurements on optical energy reflected and/or emitted by the target tissue upon illumination of the second portion of the target tissue with optical energy, and determining tissue characteristics of the target tissue based on the results of the spectroscopic measurements. The apparatus and system of the invention comprises of a base unit comprising illumination, detection and control sub-units, the illumination sub-unit providing illumination optical energy for illuminating a target tissue and the detection sub-unit detecting tissue characteristics of a target tissue, a separate tissue interface unit, and a pathway coupling the base unit and the tissue interface unit. According to other embodiments, the system and apparatus comprises of a tissue interface unit configured to perform spectroscopic measurements on a target tissue, a docking unit configured to support the tissue interface unit when not in use, the docking unit comprising an illumination source and a processor that processes spectrographic measurements results received from the tissue interface unit, and a pathway coupling the docking unit and the tissue interface unit.
摘要翻译：根据其各种实施例，本发明提供了询问，接收和分析至少一种荧光激发波长的全发射光谱和至少一种反射测量来确定组织特征的方法和装置。根据实施例，本发明的方法包括用光能照射目标组织的第一部分，形成目标组织的第一图像，用光能照射目标组织的第二部分，在光学上执行光谱测量基于光谱测量的结果，通过用能量照射目标组织的第二部分的目标组织反射和/或发射的能量，以及确定目标组织的组织特征。本发明的装置和系统包括：包括照明，检测和控制子单元的基本单元，照明子单元提供用于照射目标组织的照明光能和检测目标组织的组织特征的检测子单元，单独的组织接口单元和连接基部单元和组织接口单元的通路。根据其他实施例，系统和装置包括被配置为在目标组织上执行光谱测量的组织接口单元，配置成在不使用时支撑组织接口单元的对接单元，对接单元包括照明源和处理器其处理从组织接口单元接收的光谱测量结果，以及连接对接单元和组织接口单元的通路。

4. 发明申请

WO2002095358A2 SYSTEM AND METHOD FOR MONITORING OR TREATING A HEALTH CONDITION 审中-公开
标题翻译：用于监测或治疗健康状况的系统和方法
公开(公告)号：WO2002095358A2
公开(公告)日：2002-11-28
申请号：PCT/US2002/016130
申请日：2002-05-20
申请人： SPECTRX, INC. , FAUPEL, Mark , MARCUS, Raulee , SMITH, Alan , YANG, Difei
发明人： FAUPEL, Mark , MARCUS, Raulee , SMITH, Alan , YANG, Difei
IPC分类号： G01N
CPC分类号： A61B5/145 , A61B5/14514 , A61B5/14532 , A61B5/14546 , A61B5/441 , A61B5/4839
摘要： The present invention relates to a system and method for monitoring or treating a health condition. The method can include accessing a biological fluid, evaluating an analyte in the fluid, presenting a measurement parameter based on the evaluation, and/or administering a treatment based on the evaluation. The measurement parameter can prompt administering a treatment. The system can include a fluid handling device, a display and/or alert device, and/or an administration device. This abstract is provided for searching purposes only and is not meant for construing the claims.
摘要翻译：本发明涉及用于监测或治疗健康状况的系统和方法。该方法可以包括进入生物流体，评估流体中的分析物，基于评估呈现测量参数，和/或基于评估进行治疗。测量参数可以促进治疗。该系统可以包括流体处理装置，显示器和/或警报装置，和/或管理装置。本摘要仅用于搜索目的，而不是用于解释权利要求。

5. 发明申请

WO0057157A8 APPARATUS AND METHOD FOR DETERMINING TISSUE CHARACTERISTICS 审中-公开
标题翻译：用于确定组织特征的装置和方法
公开(公告)号：WO0057157A8
公开(公告)日：2001-03-15
申请号：PCT/US0006428
申请日：2000-03-24
申请人： SPECTRX INC , ARCHE GLEN STEVEN , BAMBOT SHABBIR B , FARQUHAR DAVID , FAUPEL MARK L , HARRELL TIM , SANDERS WALTER R , KIMBRELL EDWARD L
发明人： ARCHE GLEN STEVEN , BAMBOT SHABBIR B , FARQUHAR DAVID , FAUPEL MARK L , HARRELL TIM , SANDERS WALTER R , KIMBRELL EDWARD L
IPC分类号： A61B5/00 , G01N21/00 , G01N21/21 , G01N21/47 , G01N21/49 , G01N21/64
CPC分类号： G01N21/474 , A61B5/0059 , A61B5/0071 , A61B5/0075 , A61B5/0084 , A61B5/0091 , A61B5/4312 , A61B5/444 , A61B5/6843 , A61B2562/164 , G01N21/21 , G01N21/49 , G01N21/64
摘要： An apparatus embodying the invention includes a probe head (304) with an interrogation surface that is intended to be positioned adjacent or pushed into contact with a target material or tissue (50). The probe head (304) is constructed to have a plurality of interrogation devices (317) arranged across the face of the interrogation surface. The probe head (304) is also constructed so that the interrogation device can conform to a non-uniform or non-planar surface of the target tissue (50). In some embodiments, the interrogation surface may have a particular shape that conforms to the shape of a target material. In other embodiments, one or more portions of the interrogation surface could be movable with respect to remaining portions so that the interrogation surface can thereby conform to a non-uniform surface. In still other embodiments, a plurality of separately moveable interrogation devices can be arranged across the interrogation surface. During a measurement process, the interrogation surface would be pressed into contact with the uniform surface to cause individual ones of the interrogation devices to move, thereby causing the probe head to conform to the non-uniform surface.
摘要翻译：体现本发明的装置包括具有询问表面的探针头（304），该询问表面旨在被定位成与靶材料或组织（50）相邻或被推动接触。探头（304）被构造为具有布置在询问表面的表面上的多个询问装置（317）。探针头（304）也被构造成使得询问装置可以符合目标组织（50）的不均匀或非平面的表面。在一些实施例中，询问表面可以具有符合目标材料的形状的特定形状。在其他实施例中，询问表面的一个或多个部分可以相对于剩余部分是可移动的，使得询问表面因此可以符合不均匀的表面。在其他实施例中，可以跨越询问表面布置多个可单独移动的询问装置。在测量过程中，询问表面将被压制成与均匀表面接触，以使单个询问装置移动，从而使探针头与不均匀的表面一致。

6. 发明申请

WO2003099123A1 SYSTEM AND METHOD FOR THE EXTRACTION AND MONITORING OF A BIOLOGICAL FLUID 审中-公开
标题翻译：用于提取和监测生物流体的系统和方法
公开(公告)号：WO2003099123A1
公开(公告)日：2003-12-04
申请号：PCT/US2003/016315
申请日：2003-05-22
申请人： SPECTRX, INC. , FAUPEL, Mark , LINCOLN, Danny
发明人： FAUPEL, Mark , LINCOLN, Danny
IPC分类号： A61B5/15
CPC分类号： A61B5/155 , A61B5/14514 , A61B5/150022 , A61B5/150099 , A61B5/150213 , A61B5/150229 , A61B5/150343 , A61B5/150358 , A61B5/150969 , A61B10/0045 , A61B2010/008
摘要： Systems and methods use extraction devices for extracting and monitoring biological fluids of patients. The systems and methods involve creating an opening in the biological tissue of the patient and placing a sampling aperture of the extraction device over the opening. The sampling aperture is defined in a contact surface of the extraction device that is placed into contact with the tissue of the patient. A pump of the extraction device such as a depressible bulb sealed to the body is charged to create a vacuum between the pump through a sampling channel to the sampling aperture, and the vacuum draws the biological fluid from the tissue opening into the sampling channel. An access point is exposed to the sampling channel, and the sample of fluid may be accessed from the access point. The access point may be an extraction opening covered by an access door, and the access door is opened to access the sample. Alternatively, the access point may be electrodes extending into the sampling channel where the electrodes are connectable to a fluid analyzer device.
摘要翻译：系统和方法使用提取装置来提取和监测患者的生物液体。所述系统和方法涉及在患者的生物组织中产生开口并将提取装置的采样孔放置在开口上。取样孔限定在提取装置的与患者组织接触的接触表面中。对诸如密封到身体的可压迫的灯泡的提取装置的泵进行充电以在泵通过采样通道到采样孔之间产生真空，并且真空将生物流体从组织开口吸入采样通道。接入点暴露于采样通道，可以从接入点访问流体样本。接入点可以是由进入门覆盖的提取开口，并且访问门被打开以访问样本。或者，接入点可以是延伸到采样通道中的电极，其中电极可连接到流体分析器装置。

7. 发明申请

WO02071026A3 SYSTEM AND METHOD FOR DETERMINING TISSUE CHARACTERISTICS 审中-公开
标题翻译：用于确定组织特征的系统和方法
公开(公告)号：WO02071026A3
公开(公告)日：2003-12-18
申请号：PCT/US0206350
申请日：2002-03-01
申请人： SPECTRX INC , BAMBOT SHABBIR , FAUPEL MARK L , AGRAWAL ANANT , IGNOTZ KEITH D , FORDHAM ANDREW
发明人： BAMBOT SHABBIR , FAUPEL MARK L , AGRAWAL ANANT , IGNOTZ KEITH D , FORDHAM ANDREW
IPC分类号： A61B5/00 , A61B5/103 , A61B1/06 , A61B6/00
CPC分类号： A61B5/4331 , A61B5/0071 , A61B5/0075 , A61B5/0084 , A61B5/444
摘要： A tissue-characteristic-determining method and apparatus that analyzes full emission spectra at a fluorescence excitation wavelength and reflective measurements. The method includes illuminating a first tissue portion, forming a first image, illuminating a second tissue portion, spectroscopically measuring reflected optical energy, and determining tissue characteristics based on the spectroscopic measurements. The apparatus includes a base-unit (20) with sub-units. the sub-units include an illumination sub-unit (30), a detection sub-unit (50), and a control sub-unit (45). There is also a separate tissue interface unit (70), and a pathway (73) coupling the base unit and the tissue interface unit (70). The apparatus also includes a docking unit (120) that supports the tissue interface unit (70) when unused. The docking unit (120) further includes an illumination source (132), a processor (190), and a pathway (177).
摘要翻译：在荧光激发波长和反射测量下分析全发射光谱的组织特征确定方法和装置。该方法包括：照射第一组织部分，形成第一图像，照射第二组织部分，光谱测量反射光能，以及基于光谱测量确定组织特征。该装置包括具有子单元的基座单元（20）。子单元包括照明子单元（30），检测子单元（50）和控制子单元（45）。还存在单独的组织接口单元（70）和连接基座单元和组织接口单元（70）的通路（73）。所述装置还包括当未使用时支撑组织接口单元（70）的对接单元（120）。对接单元（120）还包括照明源（132），处理器（190）和通路（177）。

8. 发明申请

WO02095358A3 SYSTEM AND METHOD FOR MONITORING OR TREATING A HEALTH CONDITION 审中-公开
标题翻译：用于监测或治疗健康状况的系统和方法
公开(公告)号：WO02095358A3
公开(公告)日：2003-03-06
申请号：PCT/US0216130
申请日：2002-05-20
申请人： SPECTRX INC , FAUPEL MARK , MARCUS RAULEE , SMITH ALAN , YANG DIFEI
发明人： FAUPEL MARK , MARCUS RAULEE , SMITH ALAN , YANG DIFEI
IPC分类号： A61B5/00 , A61B5/103
CPC分类号： A61B5/145 , A61B5/14514 , A61B5/14532 , A61B5/14546 , A61B5/441 , A61B5/4839
摘要： The present invention relates to a system and method for monitoring or treating a health condition. The method can include accessing a biological fluid, evaluating an analyte in the fluid, presenting a measurement parameter based on the evaluation, and/or administering a treatment based on the evaluation. The measurement parameter can prompt administering a treatment. The system can include a fluid handling device, a display and/or alert device, and/or an administration device. This abstract is provided for searching purposes only and is not meant for construing the claims.
摘要翻译：本发明涉及用于监测或治疗健康状况的系统和方法。该方法可以包括进入生物流体，评估流体中的分析物，基于评估呈现测量参数，和/或基于评估进行治疗。测量参数可以促进治疗。该系统可以包括流体处理装置，显示器和/或警报装置，和/或管理装置。本摘要仅用于搜索目的，而不是用于解释权利要求。

9. 发明申请

WO2002071026A2 SYSTEM AND METHOD FOR DETERMINING TISSUE CHARACTERISTICS 审中-公开
标题翻译：用于确定组织特征的系统和方法
公开(公告)号：WO2002071026A2
公开(公告)日：2002-09-12
申请号：PCT/US2002/006350
申请日：2002-03-01
申请人： SPECTRX, INC. , BAMBOT, Shabbir , FAUPEL, Mark, L. , AGRAWAL, Anant , IGNOTZ, Keith, D. , FORDHAM, Andrew
发明人： BAMBOT, Shabbir , FAUPEL, Mark, L. , AGRAWAL, Anant , IGNOTZ, Keith, D. , FORDHAM, Andrew
IPC分类号： G01N
CPC分类号： A61B5/4331 , A61B5/0071 , A61B5/0075 , A61B5/0084 , A61B5/444
摘要： The present invention, according to its various embodiments, provides for a method and apparatus that interrogates, receives and analyzes full emission spectra for at least one fluorescence excitation wavelength and for at least one reflectance measurement to determine tissue characteristics. According to embodiments, the method of the present invention comprises of illuminating a first portion of a target tissue with optical energy, forming a first image of the target tissue, illuminating a second portion of the target tissue with optical energy, performing spectroscopic measurements on optical energy reflected and/or emitted by the target tissue upon illumination of the second portion of the target tissue with optical energy, and determining tissue characteristics of the target tissue based on the results of the spectroscopic measurements. The apparatus and system of the invention comprises of a base unit comprising illumination, detection and control sub-units, the illumination sub-unit providing illumination optical energy for illuminating a target tissue and the detection sub-unit detecting tissue characteristics of a target tissue, a separate tissue interface unit, and a pathway coupling the base unit and the tissue interface unit. According to other embodiments, the system and apparatus comprises of a tissue interface unit configured to perform spectroscopic measurements on a target tissue, a docking unit configured to support the tissue interface unit when not in use, the docking unit comprising an illumination source and a processor that processes spectrographic measurements results received from the tissue interface unit, and a pathway coupling the docking unit and the tissue interface unit.
摘要翻译：根据其各种实施例，本发明提供了询问，接收和分析至少一种荧光激发波长的全发射光谱和至少一种反射测量以确定组织特征的方法和装置。根据实施例，本发明的方法包括用光能照射目标组织的第一部分，形成目标组织的第一图像，用光能照射目标组织的第二部分，在光学上执行光谱测量基于光谱测量的结果，通过用能量照射目标组织的第二部分的目标组织反射和/或发射的能量，以及确定目标组织的组织特征。本发明的装置和系统包括：包括照明，检测和控制子单元的基本单元，照明子单元提供用于照射目标组织的照明光能和检测目标组织的组织特征的检测子单元，单独的组织接口单元和连接基部单元和组织接口单元的通路。根据其他实施例，系统和装置包括被配置为在目标组织上执行光谱测量的组织接口单元，配置成在不使用时支撑组织接口单元的对接单元，对接单元包括照明源和处理器其处理从组织接口单元接收的光谱测量结果，以及连接对接单元和组织接口单元的通路。

10. 发明申请

WO0135820A9 TISSUE INTERFACE DEVICE 审中-公开
标题翻译：组装界面装置
公开(公告)号：WO0135820A9
公开(公告)日：2002-05-16
申请号：PCT/US0031765
申请日：2000-11-17
申请人： SPECTRX INC , ALTEA TECH INC , FAUPEL MARK L , KUMAR KRISHNA , FARQUHAR DAVID , VREEKE MARK , SMITH ALAN , HATCH MICHAEL , WOODS TERESA
发明人： FAUPEL MARK L , KUMAR KRISHNA , FARQUHAR DAVID , VREEKE MARK , SMITH ALAN , HATCH MICHAEL , WOODS TERESA
IPC分类号： G01N33/487 , A61B5/00 , G01N33/48
CPC分类号： A61B5/1486
摘要： A tissue interface device (10) suitable for positioning on or about one or more artificial openings in a biological membrane of an organism and for coupling to a monitor and control unit and a vacuum source. The tissue interface device (10) comprises a housing (100), a sensor channel (130), and a sensor (150). The housing (100) defines an orifice (120), the orifice (120) having an open inlet port (122) on the bottom end (102) of the housing (100) and a distal end (124) that is in fluid communication with the sensor channel (130). The orifice (120) is in fluid communication with fluid that flows from the artificial opening formed in the biological membranes. The sensor channel (130) is for coupling to, and fluid communication therewith, the vacuum source. The sensor (150) is positioned in the sensor channel (130) in a flow path of the fluid for sensing a characteristic of the fluid as it flows out from the artificial opening. The sensor generates a sensor signal representative thereof.
摘要翻译：适于定位在生物体的生物膜中的一个或多个人造开口上或周围的组织界面装置（10），并用于耦合到监测和控制单元和真空源。组织接口装置（10）包括壳体（100），传感器通道（130）和传感器（150）。壳体（100）限定孔口（120），孔口（120）在壳体（100）的底端（102）上具有开放的入口端口（122）和远端（124），该远端端部与传感器通道（130）连接。孔口（120）与从生物膜中形成的人造开口流动的流体流体连通。传感器通道（130）用于耦合到真空源并与之流体连通。传感器（150）在流体的流动路径中位于传感器通道（130）中，用于感测流体从人造开口流出时的特性。传感器产生代表其的传感器信号。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式