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    • 1. 发明申请
    • SYSTEM AND METHOD FOR DETERMINING TISSUE CHARACTERISTICS
    • 用于确定组织特征的系统和方法
    • WO2002071026A2
    • 2002-09-12
    • PCT/US2002/006350
    • 2002-03-01
    • SPECTRX, INC.BAMBOT, ShabbirFAUPEL, Mark, L.AGRAWAL, AnantIGNOTZ, Keith, D.FORDHAM, Andrew
    • BAMBOT, ShabbirFAUPEL, Mark, L.AGRAWAL, AnantIGNOTZ, Keith, D.FORDHAM, Andrew
    • G01N
    • A61B5/4331A61B5/0071A61B5/0075A61B5/0084A61B5/444
    • The present invention, according to its various embodiments, provides for a method and apparatus that interrogates, receives and analyzes full emission spectra for at least one fluorescence excitation wavelength and for at least one reflectance measurement to determine tissue characteristics. According to embodiments, the method of the present invention comprises of illuminating a first portion of a target tissue with optical energy, forming a first image of the target tissue, illuminating a second portion of the target tissue with optical energy, performing spectroscopic measurements on optical energy reflected and/or emitted by the target tissue upon illumination of the second portion of the target tissue with optical energy, and determining tissue characteristics of the target tissue based on the results of the spectroscopic measurements. The apparatus and system of the invention comprises of a base unit comprising illumination, detection and control sub-units, the illumination sub-unit providing illumination optical energy for illuminating a target tissue and the detection sub-unit detecting tissue characteristics of a target tissue, a separate tissue interface unit, and a pathway coupling the base unit and the tissue interface unit. According to other embodiments, the system and apparatus comprises of a tissue interface unit configured to perform spectroscopic measurements on a target tissue, a docking unit configured to support the tissue interface unit when not in use, the docking unit comprising an illumination source and a processor that processes spectrographic measurements results received from the tissue interface unit, and a pathway coupling the docking unit and the tissue interface unit.
    • 根据其各种实施例,本发明提供了询问,接收和分析至少一种荧光激发波长的全发射光谱和至少一种反射测量以确定组织特征的方法和装置。 根据实施例,本发明的方法包括用光能照射目标组织的第一部分,形成目标组织的第一图像,用光能照射目标组织的第二部分,在光学上执行光谱测量 基于光谱测量的结果,通过用能量照射目标组织的第二部分的目标组织反射和/或发射的能量,以及确定目标组织的组织特征。 本发明的装置和系统包括:包括照明,检测和控制子单元的基本单元,照明子单元提供用于照射目标组织的照明光能和检测目标组织的组织特征的检测子单元, 单独的组织接口单元和连接基部单元和组织接口单元的通路。 根据其他实施例,系统和装置包括被配置为在目标组织上执行光谱测量的组织接口单元,配置成在不使用时支撑组织接口单元的对接单元,对接单元包括照明源和处理器 其处理从组织接口单元接收的光谱测量结果,以及连接对接单元和组织接口单元的通路。