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1. 发明申请

WO2019060689A1 DISCRETE VOLUME DISPENSING SYSTEM FLOW RATE AND ANALYTE SENSOR 审中-公开
公开(公告)号：WO2019060689A1
公开(公告)日：2019-03-28
申请号：PCT/US2018/052176
申请日：2018-09-21
申请人： UNIVERSITY OF CINCINNATI , ECCRINE SYSTEMS, INC.
发明人： GOMEZ, Eliot , STAMPER, Isaac , HEIKENFELD, Jason , FRANCIS, Jessica , LARSEN, Mikel , HOFFMAN, Michelle
IPC分类号： B01L3/00 , A61B5/00
CPC分类号： B01L3/502715 , A61B5/14517 , A61B5/14521 , A61B5/14532 , A61B5/1486 , A61B5/4266 , B01L2200/027 , B01L2200/0605 , B01L2300/0636 , B01L2300/0645 , B01L2300/069 , B01L2300/0825 , B01L2300/161 , B01L2300/163 , B01L2400/022 , B01L2400/0406 , G06N3/061
摘要： A device (10) for determining the amount or concentration of an analyte (1700) in a fluid sample (1500) and a flow rate (1000) of the fluid sample (1500) in a channel (14) is provided. The device (10) includes a chamber (20) including a channel (14) and an opening (12a), the channel (14) in fluid communication with the opening (12a). The device further includes a wicking component (16) positioned adjacent to the opening (12a) configured to receive an amount of fluid (1500) from the channel (14). The device may further include an analyte sensor (18) positioned on the wicking component (16), the analyte sensor (18) configured to detect an analyte (1700) in fluid ((1500) in contact with the analyte sensor (18), wherein the wicking component (16) is configured to contact the amount of fluid (1500) with the analyte sensor (18). Alternatively the device (10) may include at least one pair of electrodes (130, 132) configured to determine a flow rate (1000) of the fluid (1500) in the channel (14).

2. 发明申请

WO2017053122A1 VAGINAL RING SENSOR 审中-公开
标题翻译： VAGINAL环传感器
公开(公告)号：WO2017053122A1
公开(公告)日：2017-03-30
申请号：PCT/US2016/051444
申请日：2016-09-13
申请人： JOHNSON & JOHNSON CONSUMER INC.
发明人： FOUGERE, Richard J. , DONG, Ming
IPC分类号： A61B5/00 , A61B5/145 , A61K9/00 , A61B5/07 , A61B5/01 , A61B5/021 , A61B5/024 , A61B5/16 , A61B5/1486 , A61B5/1459
CPC分类号： A61B5/6847 , A61B5/0002 , A61B5/0011 , A61B5/0071 , A61B5/0084 , A61B5/01 , A61B5/021 , A61B5/0215 , A61B5/024 , A61B5/07 , A61B5/14503 , A61B5/14507 , A61B5/14532 , A61B5/14539 , A61B5/14546 , A61B5/1459 , A61B5/1473 , A61B5/1486 , A61B5/14865 , A61B5/165 , A61B5/4318 , A61B5/4337 , A61B5/4875 , A61B5/746 , A61B2562/12 , A61M31/00 , A61M2210/1475
摘要： A vaginal ring sensor device adapted to be placed within the vaginal vault of a user, the device including a ring body, at least one through hole that passes through the ring body, and at least one biosensor structured and arranged to sense and/or measure a parameter of vaginal fluid as such fluid passes through the at least one through hole.
摘要翻译：一种阴道环传感器装置，适于放置在使用者的阴道拱顶内，该装置包括环体，穿过环体的至少一个通孔和至少一个构造和布置成感测和/或测量的生物传感器这样的流体的参数通过至少一个通孔。

3. 发明申请

WO2015191213A1 CONDITIONAL STORAGE 审中-公开
标题翻译：条件储存
公开(公告)号：WO2015191213A1
公开(公告)日：2015-12-17
申请号：PCT/US2015/030554
申请日：2015-05-13
申请人： GOOGLE INC.
发明人： YEAGER, Daniel, James , OTIS, Brian
IPC分类号： A61B5/00 , A61B3/125 , G02C7/04
CPC分类号： A61B5/6821 , A61B3/101 , A61B3/113 , A61B5/00 , A61B5/002 , A61B5/1103 , A61B5/14532 , A61B5/1486 , A61B5/16 , A61B2560/0209 , A61B2560/0214 , G02C7/04
摘要： In one aspect of the present disclosure, a method involves obtaining, by a body-mountable device, sensor data, where the body-mountable device includes a data storage. The method further involves making a determination that each condition in a condition set has been satisfied. In addition, the method involves responsive to making the determination that each condition in the condition set has been satisfied, storing the obtained sensor data in the data storage.
摘要翻译：在本公开的一个方面，一种方法包括通过身体安装装置获得传感器数据，其中身体安装装置包括数据存储器。该方法还包括确定条件集中的每个条件已被满足。此外，该方法包括响应于确定条件集中的每个条件已被满足，将获得的传感器数据存储在数据存储器中。

4. 发明申请

WO2015100265A1 SENSOR ELECTRODES IN A BIO-COMPATIBLE DEVICE 审中-公开
标题翻译：传感器电极在一个生物兼容的设备
公开(公告)号：WO2015100265A1
公开(公告)日：2015-07-02
申请号：PCT/US2014/071985
申请日：2014-12-22
申请人： GOOGLE INC.
发明人： ETZKORN, James , HO, Harvey , LIU, Zenghe
IPC分类号： G06K9/00
CPC分类号： A61B5/6821 , A61B5/0002 , A61B5/14532 , A61B5/1486 , Y10T29/49155
摘要： A method may involve providing a conductive pattern on a bio-compatible layer. The conductive pattern may include a first conductive layer that comprises a first metal and a second conductive layer that comprises a second metal. The second conductive layer may be over the first conductive layer, and the first metal may be more malleable than the second metal. The method may also include mounting an electrical component to the conductive pattern to provide an electrochemical sensor. The electrochemical sensor may be configured for use in a body-mountable device.
摘要翻译：一种方法可以涉及在生物相容层上提供导电图案。导电图案可以包括第一导电层，其包括第一金属和包括第二金属的第二导电层。第二导电层可以在第一导电层之上，并且第一金属可以比第二金属更具有延展性。该方法还可以包括将电气部件安装到导电图案以提供电化学传感器。电化学传感器可被配置为用于体内安装的装置。

5. 发明申请

WO2015100131A1 ANALYTE SENSORS WITH ETHYLENE OXIDE IMMUNITY 审中-公开
标题翻译：具有乙烯氧化物免疫力的分析仪传感器
公开(公告)号：WO2015100131A1
公开(公告)日：2015-07-02
申请号：PCT/US2014/071170
申请日：2014-12-18
申请人： GOOGLE INC.
发明人： LIU, Zenghe
IPC分类号： C12Q1/26 , G01N27/30
CPC分类号： A61L2/206 , A61B5/14532 , A61B5/14546 , A61B5/1486 , A61B5/682 , A61B5/6821 , C12Q1/006
摘要： Analyte sensors capable of undergoing sterilization with ethylene oxide are provided. The analyte sensors can include one or more polymer membranes having a nucleophilic group.
摘要翻译：提供能够与环氧乙烷进行灭菌的分析物传感器。分析物传感器可以包括具有亲核基团的一个或多个聚合物膜。

6. 发明申请

WO2015084570A1 SENSOR MEMBRANE WITH LOW TEMPERATURE COEFFICIENT 审中-公开
标题翻译：具有低温系数的传感器膜
公开(公告)号：WO2015084570A1
公开(公告)日：2015-06-11
申请号：PCT/US2014/065905
申请日：2014-11-17
申请人： GOOGLE INC.
发明人： LIU, Zenghe
IPC分类号： G01N27/30 , G01N33/50 , C08L33/14
CPC分类号： C12Q1/006 , A61B5/14532 , A61B5/1486 , A61B5/6821 , C12Q1/002
摘要： An analyte sensor for measuring physiological parameters, a method for making the analyte sensor, and method of measuring a level of an analyte in a subject are disclosed. In one aspect, the analyte sensor includes a crosslinked, hydrophilic copolymer in contact with a surface of an electrode, and an analyte sensing component embedded within the crosslinked, hydrophilic copolymer. The crosslinked, hydrophilic copolymer has methacrylate-derived backbone chains of first methacrylate-derived units, second methacrylate-derived units and third methacrylate-derived units. The first and second methacrylate-derived units have side chains that can be the same or different, and the third methacrylate-derived units in different backbone chains are connected by hydrophilic crosslinks. The crosslinked, hydrophilic copolymer has an analyte permeability that is substantially temperature independent. The analyte sensor generates signals that are substantially temperature independent over a range of temperatures.
摘要翻译：公开了一种用于测量生理参数的分析物传感器，用于制备分析物传感器的方法和测量受试者中分析物水平的方法。一方面，分析物传感器包括与电极表面接触的交联的亲水共聚物和嵌入交联的亲水共聚物内的分析物感测组分。交联的亲水共聚物具有衍生自第一甲基丙烯酸酯单元，第二甲基丙烯酸酯衍生单元和第三甲基丙烯酸酯衍生单元的甲基丙烯酸酯衍生的主链。第一和第二甲基丙烯酸酯衍生单元具有可以相同或不同的侧链，并且不同主链中的第三甲基丙烯酸酯衍生单元通过亲水性交联连接。交联的亲水共聚物具有基本上独立于温度的分析物渗透性。分析物传感器产生在温度范围内基本上独立于温度的信号。

7. 发明申请

WO2014209998A1 CONTAINER 审中-公开
标题翻译：容器
公开(公告)号：WO2014209998A1
公开(公告)日：2014-12-31
申请号：PCT/US2014/043865
申请日：2014-06-24
申请人： GOOGLE INC.
发明人： LINHARDT, Jeffrey, George , BARROWS, Daniel
IPC分类号： A45C11/04 , A45C11/00 , B65D77/22 , B65D77/20
CPC分类号： A45C11/005 , A61B3/101 , A61B5/14507 , A61B5/14532 , A61B5/14542 , A61B5/1468 , A61B5/1486 , A61B5/6803 , A61B5/6821 , B65D25/08 , B65D77/08 , B65D2585/545
摘要： The present disclosure provides an apparatus including a first chamber containing an eye-mountable device. The apparatus may also include a second chamber containing an aqueous solution. The apparatus may also include a membrane positioned between the first chamber and the second chamber. The membrane may be configured to rupture based on application of a force to the apparatus. The ruptured membrane may allow the aqueous solution to engage with the eye-mountable device. The apparatus may also include a lid to seal one or more of the first chamber and the second chamber.
摘要翻译：本公开提供了一种包括包含眼睛安装装置的第一室的装置。该装置还可以包括含有水溶液的第二室。该装置还可以包括位于第一室和第二室之间的膜。膜可以被配置为基于对装置施加力而破裂。破裂的膜可以允许水溶液与眼睛安装的装置接合。该装置还可以包括用于密封第一室和第二室中的一个或多个的盖。

8. 发明申请

WO2014204575A1 SYMMETRICALLY ARRANGED SENSOR ELECTRODES IN AN OPHTHALMIC ELECTROCHEMICAL SENSOR 审中-公开
标题翻译：光学电化学传感器中对称的传感器电极
公开(公告)号：WO2014204575A1
公开(公告)日：2014-12-24
申请号：PCT/US2014/034839
申请日：2014-04-21
申请人： GOOGLE INC.
发明人： ETZKORN, James , LIU, Zenghe
IPC分类号： G01N27/26 , G01N27/416 , G02C7/04 , A61F2/14 , G08C17/00
CPC分类号： A61B5/1486 , A61B3/101 , A61B5/0002 , A61B5/0004 , A61B5/002 , A61B5/14507 , A61B5/14532 , A61B5/14546 , A61B5/1477 , A61B5/6821 , A61B5/7264 , A61B2560/0214 , G01N27/30 , G01N27/3271 , G01N27/4166 , G02C7/04
摘要： An eye-mountable device includes an electrochemical sensor embedded in a polymeric material configured for mounting to a surface of an eye. The electrochemical sensor includes a working electrode, a reference electrode, and a reagent that selectively reacts with an analyte to generate a sensor measurement related to a concentration of the analyte in a fluid to which the eye-mountable device is exposed. The working electrode can have a first side edge and a second side edge. The reference electrode can be situated such that at least a portion of the first and second side edges of the working electrode are adjacent respective sections of the reference electrode.
摘要翻译：一种可眼睛安装的装置包括嵌入聚合物材料中的电化学传感器，其被配置用于安装到眼睛的表面。电化学传感器包括工作电极，参比电极和选择性地与分析物反应以产生与可眼睛安装的装置暴露于的流体中的分析物的浓度相关的传感器测量的试剂。工作电极可以具有第一侧边缘和第二侧边缘。参考电极可以被定位成使得工作电极的第一和第二侧边缘的至少一部分与参考电极的相应部分相邻。

9. 发明申请

WO2014160893A3 ALL-IN-ONE ANALYTE SENSOR IN A DETACHABLE EXTERNAL MOBILE DEVICE CASE 审中-公开
标题翻译：一个可拆卸的外部移动设备案例中的一体化分析传感器
公开(公告)号：WO2014160893A3
公开(公告)日：2014-12-11
申请号：PCT/US2014032076
申请日：2014-03-27
申请人： ISMAIL MOUSSA , ISMAIL HAROON , HABIB AAQIB , MASOOD FAHAD
发明人： ISMAIL MOUSSA , ISMAIL HAROON , HABIB AAQIB , MASOOD FAHAD
IPC分类号： A61B5/157 , A61B5/145 , A61B5/151 , G01N33/48 , G01N33/66
CPC分类号： A61B5/14532 , A61B5/0015 , A61B5/1486 , A61B5/150022 , A61B5/150175 , A61B5/150358 , A61B5/150412 , A61B5/150854 , A61B5/15087 , A61B5/151 , A61B5/15113 , A61B5/15146 , A61B5/157 , A61B5/742 , A61B2562/0295
摘要： The embodiments herein discuss an analyte sensing processor housed in the external, detachable case of a mobile device. The analyte sensing processor converts the reading into a signal that can be further processed by a health management system and displayed on the graphical user interface of a user's device.
摘要翻译：这里的实施例讨论容纳在移动设备的外部可拆卸壳体中的分析物感测处理器。分析物检测处理器将读数转换为可由健康管理系统进一步处理并显示在用户设备的图形用户界面上的信号。

10. 发明申请

WO2014149514A1 MICROFLUIDIC SYSTEMS FOR ELECTROCHEMICAL TRANSDERMAL ANALYTE SENSING 审中-公开
标题翻译：电化学分析仪感应微电子系统
公开(公告)号：WO2014149514A1
公开(公告)日：2014-09-25
申请号：PCT/US2014/019183
申请日：2014-02-28
申请人： GEORGETOWN UNIVERSITY
发明人： MAKARAND, Paranjape
IPC分类号： A61B5/05 , A61N1/04 , A61N1/18
CPC分类号： A61B5/14532 , A61B5/14514 , A61B5/1477 , A61B5/1486 , A61B5/1491
摘要： A sensing device, designed to be used in contact with the skin, contains a plurality of individually controllable sites for electrochemically monitoring an analyte, such as glucose, in interstitial fluid of a user. The device includes at least a hydrophobic layer designed to contact the skin; a capillary channel providing an opening adjacent the skin; a metal electrode layer having a sensor layer applied to an edge portion thereof such that it is exposed to the interior of said capillary channel, the sensing layer being effective to measure the analyte.
摘要翻译：设计用于与皮肤接触的感测装置包含多个可独立控制的位置，用于在用户的间质液中电化学监测分析物，例如葡萄糖。该装置至少包括设计成接触皮肤的疏水层; 提供邻近皮肤的开口的毛细通道; 金属电极层，其具有施加到其边缘部分的传感器层，使得其暴露于所述毛细通道的内部，感测层有效地测量分析物。

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