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11. 发明申请

WO2012004083A1 POWER-SUPPLY CIRCUIT 审中-公开
标题翻译：电源电路
公开(公告)号：WO2012004083A1
公开(公告)日：2012-01-12
申请号：PCT/EP2011/059632
申请日：2011-06-09
申请人： ST-ERICSSON SA , JOHANSSON, Henrik
发明人： JOHANSSON, Henrik
IPC分类号： G05F1/577 , H02M3/335
CPC分类号： G05F1/577 , H02M1/44 , H02M3/156 , H02M2001/0045 , H02M2001/0048 , Y02B70/1491
摘要： A power-supply circuit (10) for an electronic circuit (2) having a plurality of functional units (5-1,...,5-N) is disclosed. The power-supply circuit (10) comprises a plurality of supply-voltage regulators (30-1,...,30-N), each adapted to provide an output supply voltage to a corresponding one of the functional units (5-1,...,5-N) and each having a disabled and an enabled state. Furthermore, the power-supply circuit (10) comprises a preregulator (20) adapted to provide a common intermediate supply voltage to all of the supply-voltage regulators (30-1,...,30-N), wherein the preregulator (20) is adapted to generate the intermediate supply voltage such that it follows a reference level of the preregulator. Moreover, the power-supply circuit (10) comprises a control unit (40) adapted to control the reference level of the preregulator (20) at least based on which of the supply-voltage regulators (30-1,...,30-N) are currently in the enabled state and which of the supply-voltage regulators (30-1,...,30-N) are currently in the disabled state. A related method of operating the power-supply circuit (10), a related computer program product, and a related computer-readable medium are also disclosed.
摘要翻译：公开了一种具有多个功能单元（5-1，...，5-N）的电子电路（2）的电源电路（10）。电源电路（10）包括多个供电电压调节器（30-1，...，30-N），每个电源电压调节器适于向相应的一个功能单元（5-1）提供输出电源电压，...，5-N），并且每个具有禁用和启用状态。此外，电源电路（10）包括预调节器（20），其适于向所有电源电压调节器（30-1，...，30-N）提供公共的中间供电电压，其中预调节器 20）适于产生中间电源电压，使得其遵循前置调节器的参考电平。此外，电源电路（10）包括控制单元（40），该控制单元（40）至少基于哪个电源 - 稳压器（30-1，...，30）来控制预调节器（20）的参考电平 -N）当前处于使能状态，哪个电源电压调节器（30-1，...，30-N）当前处于禁用状态。还公开了操作电源电路（10）的相关方法，相关的计算机程序产品和相关的计算机可读介质。

12. 发明申请

WO2009142569A1 PHENYL OR PYRIDINYL SUBSTITUTED INDAZOLES DERIVATIVES 审中-公开
标题翻译：苯基或吡啶基取代的吲哚衍生物
公开(公告)号：WO2009142569A1
公开(公告)日：2009-11-26
申请号：PCT/SE2009/000265
申请日：2009-05-20
申请人： ASTRAZENECA AB , BAYER SCHERING PHARMA AG , BERGER, Markus , DAHMEN, Jan , EDMAN Karl , HANSSON, Thomas , HEMMERLING, Martin , HOSSAIN, Nafizal , JOHANSSON, Henrik , LEPISTÖ, Matti , NILSSON, Stinabritt , REHWINKEL, Hartmut
发明人： BAYER SCHERING PHARMA AG , BERGER, Markus , DAHMEN, Jan , EDMAN Karl , HANSSON, Thomas , HEMMERLING, Martin , HOSSAIN, Nafizal , JOHANSSON, Henrik , LEPISTÖ, Matti , NILSSON, Stinabritt , REHWINKEL, Hartmut
IPC分类号： C07D231/56 , A61K31/416 , A61K31/422 , A61K31/4439 , A61K31/444 , A61P11/00 , A61P29/00 , C07D401/12 , C07D401/14 , C07D403/10 , C07D403/12 , C07D407/14 , C07D409/12 , C07D409/14 , C07D413/12
CPC分类号： C07D409/14 , A61K31/416 , A61K31/4439 , A61K45/06 , C07D231/56 , C07D401/12 , C07D401/14 , C07D403/10 , C07D403/12 , C07D405/10 , C07D405/12 , C07D405/14 , C07D407/14 , C07D409/12 , C07D413/12
摘要： A compound of formula Ia: Formula (la) The present invention relates to novel indazolyl derivatives, to pharmaceutical compositions comprising such derivatives, to processes for preparing such novel derivatives and to the use of such derivatives as medicaments.
摘要翻译：式Ia化合物：式（Ia）本发明涉及新的吲唑基衍生物，包含该衍生物的药物组合物，制备这种新型衍生物的方法以及使用这些衍生物作为药物。

13. 发明申请

WO2008153492A1 METHOD FOR INTRODUCING COMMON AND/OR INDIVIDUAL SEQUENCE ELEMENTS IN A TARGET NUCLEIC ACID MOLECULE 审中-公开
标题翻译：在目标核酸分子中引入通用和/或个体序列元件的方法
公开(公告)号：WO2008153492A1
公开(公告)日：2008-12-18
申请号：PCT/SE2008/050694
申请日：2008-06-11
申请人： JOHANSSON, Henrik , ERICSSON, Olof
发明人： JOHANSSON, Henrik , ERICSSON, Olof
IPC分类号： C12Q1/68
CPC分类号： C12N15/1065 , C12N15/10
摘要： The invention relates to a method for introducing common and/or individual sequence elements in a target nucleic acid molecule in a sample containing sample nucleic acid molecules, comprising the steps i) denaturing the sample nucleic acid molecules, if the sample nucleic acid molecules are double-stranded, to obtain single stranded sample nucleic acid molecules ii) bringing the sample nucleic acid molecules in contact with primary, secondary and tertiary probe nucleic acid molecules, wherein the 3 '-end of the tertiary probe comprise a part complementary to the primary probe and the 5 '-end of the tertiary probe comprise a part complementary to a 5 '-part of the target nucleic acid molecule; the 3 '-end of the secondary probe is complementary to a 3 '-part of the target nucleic acid molecule and the 5 '-end of the secondary probe is not complementary to the target nucleic acid molecule; wherein said primary, secondary and tertiary probes comprise said common and/ or individual sequence elements; iii) ligating the 3 '-end of the primary probe to the 5 '-end of the target nucleic acid molecule; and iv) elongating the 3 '-end of the secondary probe by means of a nucleic acid polymerase; or iv') elongating the 3'-end of the target nucleic acid molecule.
摘要翻译：本发明涉及在含有样品核酸分子的样品中引入靶核酸分子中的常见和/或单个序列元件的方法，其包括以下步骤：i）如果样品核酸分子是双重的，则使样品核酸分子变性以获得单链样品核酸分子ii）使样品核酸分子与初级，次级和第三级探针核酸分子接触，其中第三级探针的3'末端包含与主要探针互补的部分并且第三探针的5'末端包含与靶核酸分子的5'部分互补的部分; 第二探针的3'末端与靶核酸分子的3'部分互补，并且第二探针的5'末端与靶核酸分子不互补; 其中所述初级，次级和第三级探针包括所述共同和/或单个序列元件; iii）将主要探针的3'端连接到靶核酸分子的5'末端; 和iv）通过核酸聚合酶延伸第二探针的3'末端; 或iv'）延伸靶核酸分子的3'末端。

14. 发明申请

WO2013036191A1 AGRICULTURAL IMPLEMENT HAVING HEIGHT ADJUSTMENT AND METHOD OF ADJUSTING HEIGHT OF AGRICULTURAL IMPLEMENT 审中-公开
标题翻译：具有高度调整的农业实施和调整农业实施高度的方法
公开(公告)号：WO2013036191A1
公开(公告)日：2013-03-14
申请号：PCT/SE2012/050936
申请日：2012-09-04
申请人： VÄDERSTAD-VERKEN AB , JOHANSSON, Henrik , STARK, Crister
发明人： JOHANSSON, Henrik , STARK, Crister
IPC分类号： A01B63/32 , A01B73/04 , A01B63/22 , A01B63/24 , A01B63/111 , A01B63/16
CPC分类号： A01B63/002 , A01B63/16 , A01B63/22 , A01B63/24 , A01B63/32 , A01B73/02
摘要： An agricultural implement (1) for soil cultivation comprises a main frame (10, 10' 10''), a side section frame (31a, 31b), which is rotatable relative to the main frame (10, 10' 10''), at least one transport wheel (11), at least one tilling tool (12), at least one ground-contacting depth holder (13), associated with the side section frame (31a, 31b), for controlling a working depth for the said tilling tool (12), and a first actuator (18), for controlling a height position for the said transport wheel (11) relative to the main frame (10, 10' 10''), or for controlling a height position for the said depth holder (13) relative to the main frame (10, 10' 10"). The depth holder (13) is connected to the transport wheel (11), so that both the height position of the depth holder and the height position of the transport wheel are simultaneously controllable by the said first actuator (18).
摘要翻译：用于土壤栽培的农具（1）包括主框架（10,10'10“），可相对于主框架（10,10'10”）旋转的侧部框架（31a，31b），至少一个运送轮（11），至少一个耕作工具（12），与所述侧部框架（31a，31b）相关联的至少一个接地深度保持器（13），用于控制所述侧部所述耕作工具（12）和用于控制所述运输轮（11）相对于主框架（10,10'10“）的高度位置的第一致动器（18），或用于控制用于所述深度保持器（13）相对于主框架（10,10'10“），深度保持器（13）连接到输送轮（11），使得深度保持器的高度位置和高度传送轮的位置可由所述第一致动器（18）同时控制。

15. 发明申请

WO2013007440A1 FRAME FOR A GYRATORY CRUSHER 审中-公开
标题翻译：摇篮的框架
公开(公告)号：WO2013007440A1
公开(公告)日：2013-01-17
申请号：PCT/EP2012/059962
申请日：2012-05-29
申请人： SANDVIK INTELLECTUAL PROPERTY AB , JOHANSSON, Henrik , NILSSON, Martin
发明人： JOHANSSON, Henrik , NILSSON, Martin
IPC分类号： B02C2/04
CPC分类号： B02C2/04 , B02C2/042
摘要： A gyratory crusher comprising a frame and a crushing head, which is arranged rotatably about a substantially vertical shaft, the frame comprising an upper frame portion, and a lower frame portion (42), which lower frame portion comprises a hub (43), which hub comprises a centralized arranged through hole (404) with a centre axis extending through said hole (404) and the hub, which hole is arranged to cooperate with the shaft being turnable arranged in said hole, which hub is connected by arms (44) to the lower frame portion (42) and comprises a drive ring pocket (64). The hub (43) further comprises a waist portion (402) with a thickness in a radial direction from the centre axis (80) being larger than the width of the drive ring pocket (64) of the hub.
摘要翻译：一种旋转式破碎机，包括框架和破碎头，所述框架和破碎头围绕基本垂直的轴可旋转地布置，所述框架包括上框架部分和下框架部分，所述下框架部分包括轮毂，毂包括具有延伸穿过所述孔（404）和毂的中心轴线的集中布置的通孔（404），该孔被布置成与可转动地布置在所述孔中的轴配合，该毂通过臂（44）连接，到下框架部分（42）并且包括驱动环口袋（64）。轮毂（43）还包括从中心轴线（80）的径向方向上的厚度大于轮毂的驱动环口（64）的宽度的腰部（402）。

16. 发明申请

WO2010039088A1 CHEMICALLY MODIFIED CELL-PENETRATING PEPTIDES FOR IMPROVED DELIVERY OF GENE MODULATING COMPOUNDS 审中-公开
标题翻译：用于改进基因调节化合物递送的化学改性细胞培养基
公开(公告)号：WO2010039088A1
公开(公告)日：2010-04-08
申请号：PCT/SE2009/051032
申请日：2009-09-16
申请人： AHMED, Kariem , EL ANDALOUSSI, Samir , GUTERSTAM, Peter , HÄLLBRINK, Mattias , JOHANSSON, Henrik , LANGEL, Ülo , LEHTO, Taavi , LINDGREN, Maria , MÄGER, Imre , SILLARD, Rannar , ROSENTHAL AIZMAN, Katri , TEDEBARK, Ulf , LUNDIN, Per
发明人： AHMED, Kariem , EL ANDALOUSSI, Samir , GUTERSTAM, Peter , HÄLLBRINK, Mattias , JOHANSSON, Henrik , LANGEL, Ülo , LEHTO, Taavi , LINDGREN, Maria , MÄGER, Imre , SILLARD, Rannar , ROSENTHAL AIZMAN, Katri , TEDEBARK, Ulf , LUNDIN, Per
IPC分类号： A61K47/48 , A61K31/00 , A61K31/20 , A61K38/16 , C07K1/107 , C07K14/00 , C07K7/08
CPC分类号： A61K49/0004 , A61K31/20 , A61K38/00 , A61K47/543 , A61K47/641 , A61K47/6455 , C07K7/06 , C07K7/08 , C07K9/00 , C07K14/001 , C12N15/87 , Y02P20/582
摘要： The present invention relates to a system for intracellular delivery of a cargo comprising at least one component A chosen from aliphatic linear or branched moieties with at least 4 carbon and/or cyclic ring systems comprising 2-4 rings which may contain several hetero atoms chosen from N, S, O and P, wherein component(s) A is (are) attached to a cell penetrating peptide B and/or a non-peptide analogue thereof. It also relates to the use of the system in diagnosis of deceases, as research tool and as a targeting system, a composition comprising the system and especially a pharmaceutical composition a material covered with the system and a material having the delivery systems into the material. Finally it relates to novel peptides.
摘要翻译：本发明涉及一种用于细胞内递送货物的系统，其包含至少一种选自脂族直链或支链部分的组分A和至少4个碳环和/或环环系统，其包含2-4个环，其可以含有选自以下的多个杂原子 N，S，O和P，其中组分A连接到穿透肽B的细胞和/或其非肽类似物。它还涉及该系统在诊断死亡中的用途，作为研究工具和作为靶向系统的组合物，包含该系统的组合物，特别是药物组合物包含在该系统中的材料以及具有输送系统进入该材料的材料。最后涉及新型肽。

17. 发明申请

WO2004016611A1 USE OF AND SOME NOVEL IMIDAZOPYRIDINES 审中-公开
标题翻译：使用和一些新的咪唑吡啶
公开(公告)号：WO2004016611A1
公开(公告)日：2004-02-26
申请号：PCT/SE2003/001279
申请日：2003-08-13
申请人： ASTRAZENECA AB , JOHANSSON, Henrik , LAWITZ, Karolina , NIKITIDIS, Grigorios , SJÖ, Peter , STORM, Peter
发明人： JOHANSSON, Henrik , LAWITZ, Karolina , NIKITIDIS, Grigorios , SJÖ, Peter , STORM, Peter
IPC分类号： C07D471/04
CPC分类号： C07D471/04 , A61K31/437
摘要： The use of compounds of formula (I) wherein R 1 , R 3 , R 10 , m and Ar are as defined in the Specification and pharmaceutically acceptable salts thereof in the manufacture of a medicament for the treatment or prophylaxis of diseases or conditions in which inhibition of kinase Itk activity is beneficial is disclosed. Certain novel compounds of formula (I), together with processes for their preparation, compositions containing them and their use in therapy are also disclosed.
摘要翻译：使用其中R 1，R 3，R 10，m和Ar的式（I）化合物如本说明书及其药学上可接受的盐所定义，用于制备用于治疗或预防的药物公开了抑制激酶Itk活性有益的疾病或病症。还公开了某些新的式（I）化合物及其制备方法，含有它们的组合物及其在治疗中的用途。

18. 发明申请

WO2012056236A2 ANALYTICAL METHODS AND ARRAYS FOR USE IN THE SAME 审中-公开
标题翻译：分析方法和使用的阵列
公开(公告)号：WO2012056236A2
公开(公告)日：2012-05-03
申请号：PCT/GB2011/052082
申请日：2011-10-26
申请人： SENZAGEN AB , SMITH, Stephen Edward , LINDSTEDT, Malin , BORREBAECK, Carl A K , JOHANSSON, Henrik , ALBREKT, Ann-Sofie
发明人： LINDSTEDT, Malin , BORREBAECK, Carl A K , JOHANSSON, Henrik , ALBREKT, Ann-Sofie
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6883 , C12Q1/6876 , C12Q2600/148 , C12Q2600/158 , G01N33/5023 , G01N33/5044 , G01N33/5047
摘要： The present invention relates to an in vitro method for identifying agents capable of inducing sensitization of human skin and arrays and diagnostic kits for use in such methods. In particular, the methods include measurement of the expression of the biomarkers listed in Table 3A and/or 3B in MUTZ-3 cells exposed to a test agent.
摘要翻译：本发明涉及一种用于鉴定能够诱导人皮肤和阵列致敏的试剂的体外方法以及用于这些方法的诊断试剂盒。特别地，所述方法包括测量暴露于测试试剂的MUTZ-3细胞中表3A和/或3B中列出的生物标志物的表达。

19. 发明申请

WO2011067378A1 METHOD FOR AMPLIFICATION OF TARGET NUCLEIC ACID 审中-公开
标题翻译：放射性核酸的方法
公开(公告)号：WO2011067378A1
公开(公告)日：2011-06-09
申请号：PCT/EP2010/068837
申请日：2010-12-03
申请人： OLINK GENOMICS AB , ERICSSON, Olof , ISAKSSON, Magnus , JOHANSSON, Henrik , ROOS, Fredrik , FREDRIKSSON, Simon , NILSSON, Mats
发明人： ERICSSON, Olof , ISAKSSON, Magnus , JOHANSSON, Henrik , ROOS, Fredrik , FREDRIKSSON, Simon , NILSSON, Mats
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6837 , C12Q2565/519 , C12Q2531/125 , C12Q2563/131 , C12Q2525/161 , C12Q2521/501
摘要： The present invention provides a method for amplifying at least one target nucleic acid in a nucleic acid sample, comprising:(a) fragmenting the nucleic acid sample to create at least one target fragment comprising said target nucleic acid and comprising two probe-complementary portions, wherein at least one of said two probe-complementary portions is located at an end of the target fragment; (b) contacting said fragmented nucleic acid sample with at least one probe which is provided with an immobilisation moiety and optionally is immobilised on a solid phase by means of said moiety, and which comprises two target fragment-complementary portions which are complementary in sequence to the probe- complementary portions of the target fragment, wherein said portions of the probe may be adjacent, or separated by an intervening non-target fragment-complementary portion; (c) rendering the fragmented nucleic acid sample single- stranded, wherein the step may occur before, contemporaneously with or after step (b); (d) allowing the probe-complementary portions of the target fragment to hybridise with the target-fragment complementary portions of the probe; (e) if the probe provided in step (b) is not immobilised, immobilising the probe-target fragment hybrid on a solid phase by means of said immobilisation moiety; (f) separating non-immobilised nucleic acid fragments from the solid phase; (g) contacting the solid phase with a ligase to ligate, directly or indirectly, ligatable 5' and 3' ends of the target fragment whereby the target fragment is circularised, wherein where one of said probe-complementary portions of the target fragment is not located at an end of the target fragment, the ligatable end, other than that at which a probe-complementary portion is located, is created by the action of a flap endonuclease or an exonuclease; and (h) amplifying said circularised target fragment. Kits for use in the method of the invention are also provided.
摘要翻译：本发明提供了用于扩增核酸样品中的至少一种靶核酸的方法，其包括：（a）使核酸样品片段化以产生至少一个包含所述靶核酸的靶片段并且包含两个探针互补部分，其中所述两个探针互补部分中的至少一个位于所述靶片段的末端; （b）使所述片段化的核酸样品与至少一个具有固定部分的探针接触，并且任选地通过所述部分固定在固相上，并且其包含两个靶序列互补部分，其与序列互补所述靶片段的探针互补部分，其中所述探针的所述部分可以相邻，或由介入的非靶片段互补部分分开; （c）使所述片段化的核酸样品单链，其中所述步骤可以在步骤（b）之前或之后发生; （d）允许靶片段的探针互补部分与探针的靶 - 片段互补部分杂交; （e）如果步骤（b）中提供的探针未被固定，则通过所述固定部分将探针 - 靶片段杂交体固定在固相上; （f）从固相中分离未固定的核酸片段; （g）使固相与连接酶接触直接或间接连接目标片段的5'和3'末端，由此靶片段是环化的，其中靶片段的所述探针互补部分之一不是位于靶片段的末端，通过翼片内切核酸酶或外切核酸酶的作用产生除了探针互补部分所位于之外的可连接末端; 和（h）扩增所述环化的靶片段。还提供了用于本发明方法的试剂盒。

20. 发明申请

WO2010126446A1 DEMOUNTABLE FLOORING 审中-公开
标题翻译：不可接受的地板
公开(公告)号：WO2010126446A1
公开(公告)日：2010-11-04
申请号：PCT/SE2010/050475
申请日：2010-04-29
申请人： MON.ZON DEVELOPMENT AB , JOHANSSON, Henrik , CARLBOM, Lars
发明人： JOHANSSON, Henrik , CARLBOM, Lars
IPC分类号： E04H3/24 , E04F15/024
CPC分类号： E04H3/28 , E04G1/151 , E04H3/24
摘要： An edge profile (1) for connection of a decking member (2) to a supporting frame in a demountable flooring construction is provided. Said edge profile (1) has a top end, a bottom end and two side walls between the top end and the bottom end. A first projection unit (3) extends towards the bottom end of said edge profile (1) and is positioned at one of said side walls of said edge profile (1). Said edge profile (1) further comprises at least one second projection unit (4) extending towards the bottom end of said edge profile (1) and positioned at a distance from said first projection unit (3). The first and second projection units define a substantially U-shaped cavity (5) there between.
摘要翻译：提供了一种用于在可拆卸的地板结构中将甲板构件（2）连接到支撑框架的边缘轮廓（1）。所述边缘轮廓（1）具有顶端，底端和在顶端和底端之间的两个侧壁。第一投影单元（3）朝着所述边缘轮廓（1）的底端延伸并且被定位在所述边缘轮廓（1）的所述侧壁之一处。所述边缘轮廓（1）还包括朝向所述边缘轮廓（1）的底端延伸并且定位在离所述第一投影单元（3）一定距离处的至少一个第二投影单元（4）。第一和第二投影单元在其间限定基本上为U形的空腔（5）。

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