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1. 发明申请

WO2008006627A1 BENZYL AMINES, A PROCESS FOR THEIR PRODUCTION AND THEIR USE AS ANTI-INFLAMMATORY AGENTS 审中-公开
标题翻译：苯甲酰胺，其生产工艺及其作为抗炎剂的用途
公开(公告)号：WO2008006627A1
公开(公告)日：2008-01-17
申请号：PCT/EP2007/006472
申请日：2007-07-16
申请人： BAYER SCHERING PHARMA AKTIENGESELLSCHAFT , ASTRAZENECA AB , BERGER, Markus , DAHMEN, Jan , REHWINKEL, Hartmut , JAROCH, Stefan , SCHAECKE, Heike
发明人： BERGER, Markus , DAHMEN, Jan , REHWINKEL, Hartmut , JAROCH, Stefan , SCHAECKE, Heike
IPC分类号： C07C215/16 , C07D215/38 , A61K31/136 , C07D401/12 , C07D405/14 , C07D405/12 , C07C217/78
CPC分类号： C07C215/16 , C07B2200/07 , C07C215/28 , C07C217/70 , C07C317/28 , C07D215/38 , C07D233/84 , C07D401/12 , C07D405/12 , C07D405/14
摘要： The present invention relates to the compounds of formula (I), processes for their production and their use as anti-inflammatory agents.
摘要翻译：本发明涉及式（I）化合物，其制备方法及其作为抗炎剂的用途。

2. 发明申请

WO2009142571A1 PHENYL AND BENZODIOXINYL SUBSTITUTED INDAZOLES DERIVATIVES 审中-公开
标题翻译：苯并噻唑啉衍生物衍生物
公开(公告)号：WO2009142571A1
公开(公告)日：2009-11-26
申请号：PCT/SE2009000267
申请日：2009-05-20
申请人： ASTRAZENECA AB , BAYER SCHERING PHARMA AG , BERGER MARKUS , DAHMEN JAN , EDMAN KARL , ERIKSSON ANDERS , HANSSON THOMAS , HEMMERLING MARTIN , HOSSAIN NAFIZAL , KLINGSTEDT TOMAS , LEPISTOE MATTI , NILSSON STINABRITT , REHWINKEL HARTMUT
发明人： BAYER SCHERING PHARMA AG , BERGER MARKUS , DAHMEN JAN , EDMAN KARL , ERIKSSON ANDERS , HANSSON THOMAS , HEMMERLING MARTIN , HOSSAIN NAFIZAL , KLINGSTEDT TOMAS , LEPISTOE MATTI , NILSSON STINABRITT , REHWINKEL HARTMUT
IPC分类号： C07D409/14 , A61K31/416 , A61K31/4439 , A61P11/00 , A61P29/00 , C07D407/12 , C07D407/14
CPC分类号： C07D409/14 , A61K31/416 , A61K31/4439 , A61K45/06 , C07D231/56 , C07D401/12 , C07D401/14 , C07D403/10 , C07D403/12 , C07D405/10 , C07D405/12 , C07D405/14 , C07D407/14 , C07D409/12 , C07D413/12
摘要： A compound of formula la: (Ia) The present invention relates to novel indazolyl derivatives, to pharmaceutical compositions comprising such derivatives, to processes for preparing such novel derivatives and to the use of such derivatives as medicaments.
摘要翻译：式Ia化合物：（Ia）本发明涉及新的吲唑基衍生物，包含该衍生物的药物组合物，制备这种新型衍生物的方法以及使用这些衍生物作为药物。

3. 发明申请

WO2009142569A1 PHENYL OR PYRIDINYL SUBSTITUTED INDAZOLES DERIVATIVES 审中-公开
标题翻译：苯基或吡啶基取代的吲哚衍生物
公开(公告)号：WO2009142569A1
公开(公告)日：2009-11-26
申请号：PCT/SE2009/000265
申请日：2009-05-20
申请人： ASTRAZENECA AB , BAYER SCHERING PHARMA AG , BERGER, Markus , DAHMEN, Jan , EDMAN Karl , HANSSON, Thomas , HEMMERLING, Martin , HOSSAIN, Nafizal , JOHANSSON, Henrik , LEPISTÖ, Matti , NILSSON, Stinabritt , REHWINKEL, Hartmut
发明人： BAYER SCHERING PHARMA AG , BERGER, Markus , DAHMEN, Jan , EDMAN Karl , HANSSON, Thomas , HEMMERLING, Martin , HOSSAIN, Nafizal , JOHANSSON, Henrik , LEPISTÖ, Matti , NILSSON, Stinabritt , REHWINKEL, Hartmut
IPC分类号： C07D231/56 , A61K31/416 , A61K31/422 , A61K31/4439 , A61K31/444 , A61P11/00 , A61P29/00 , C07D401/12 , C07D401/14 , C07D403/10 , C07D403/12 , C07D407/14 , C07D409/12 , C07D409/14 , C07D413/12
CPC分类号： C07D409/14 , A61K31/416 , A61K31/4439 , A61K45/06 , C07D231/56 , C07D401/12 , C07D401/14 , C07D403/10 , C07D403/12 , C07D405/10 , C07D405/12 , C07D405/14 , C07D407/14 , C07D409/12 , C07D413/12
摘要： A compound of formula Ia: Formula (la) The present invention relates to novel indazolyl derivatives, to pharmaceutical compositions comprising such derivatives, to processes for preparing such novel derivatives and to the use of such derivatives as medicaments.
摘要翻译：式Ia化合物：式（Ia）本发明涉及新的吲唑基衍生物，包含该衍生物的药物组合物，制备这种新型衍生物的方法以及使用这些衍生物作为药物。

4. 发明申请

WO2004016615A1 PYRAZOLO (4,3c) CINNOLINE COMPOUNDS AS INHIBITORS OF ITK KINASE ACTIVITY 审中-公开
标题翻译： PYRAZOLO（4,3c）作为ITK激酶活性的抑制剂的氰基化合物
公开(公告)号：WO2004016615A1
公开(公告)日：2004-02-26
申请号：PCT/SE2003/001278
申请日：2003-08-13
申请人： ASTRAZENECA AB , DAHMEN, Jan , HEMMERLING, Martin , KLINGSTEDT, Tomas , SJÖ, Peter
发明人： DAHMEN, Jan , HEMMERLING, Martin , KLINGSTEDT, Tomas , SJÖ, Peter
IPC分类号： C07D487/04
CPC分类号： C07D487/04
摘要： There are provided novel compounds of formula (I) wherein R and X are as defined in the Specification and optical isomers, racemates and tautomers thereof, and pharmaceutically acceptable salts thereof; together with processes for their preparation, compositions containing them and their use in therapy. The compounds are inhibitors of the kinase Itk.
摘要翻译：提供新的式（I）化合物，其中R和X如本说明书和光学异构体，外消旋体和互变异构体及其药学上可接受的盐所定义; 以及其制备方法，含有它们的组合物及其在治疗中的用途。这些化合物是激酶Itk的抑制剂。

5. 发明申请

WO1997007422A1 ENDOSCOPE WITH VARIABLE MAGNIFICATION 审中-公开
标题翻译： SCOPE变倍
公开(公告)号：WO1997007422A1
公开(公告)日：1997-02-27
申请号：PCT/DE1996001529
申请日：1996-08-19
申请人： KARL STORZ GMBH & CO. , RUDISCHHAUSER, Jürgen , LEDERER, Frank , DAHMEN, Jan
发明人： KARL STORZ GMBH & CO.
IPC分类号： G02B23/24
CPC分类号： G02B23/2438
摘要： An endoscope has an objective arranged at its distal end, an image retransmitter that transmits the objective image to the proximal end and an eyepiece made of several groups through which the image transmitted by the image retransmitter is observed. The magnification of the eyepiece image is adjusted by moving at least one group of lenses and focusing is achieved by moving all groups of lenses of the eyepiece. The disclosed endoscope is characterised in that the lenses of the eyepiece that are not moved to adjust magnification are held in a first tube in which slides at least another tube for holding a group of lenses moved to adjust magnification.
摘要翻译：公开的是具有附接至内窥镜透镜，图像发送器，其发送该内窥镜透镜到近端的图像的前端的内窥镜，和由多于一个组的目镜的一组通过其从所述图像发送器的图像的发送的观看并且将所生成的放大率的调整通过移动允许在至少一个透镜组以及通过移动所述目镜的所有透镜组聚焦目镜的图像。本发明的内窥镜的特征在于，所述非移位以目镜的放大透镜的调整中的第一管，其中另一种管至少被引导，其中，转移到调整倍率透镜组保持被保持。

6. 发明申请

WO2009142571A8 PHENYL AND BENZODIOXINYL SUBSTITUTED INDAZOLES DERIVATIVES 审中-公开
公开(公告)号：WO2009142571A8
公开(公告)日：2009-11-26
申请号：PCT/SE2009/000267
申请日：2009-05-20
申请人： ASTRAZENECA AB , BAYER SCHERING PHARMA AG , BERGER, Markus , DAHMEN, Jan , EDMAN, Karl , ERIKSSON, Anders , HANSSON, Thomas , HEMMERLING, Martin , HOSSAIN Nafizal , KLINGSTEDT, Tomas , LEPISTÖ, Matti , NILSSON, Stinabritt , REHWINKEL, Hartmut
发明人： BERGER, Markus , DAHMEN, Jan , EDMAN, Karl , ERIKSSON, Anders , HANSSON, Thomas , HEMMERLING, Martin , HOSSAIN Nafizal , KLINGSTEDT, Tomas , LEPISTÖ, Matti , NILSSON, Stinabritt , REHWINKEL, Hartmut
IPC分类号： C07D409/14 , A61K31/416 , A61K31/4439 , A61P11/00 , A61P29/00 , C07D407/12 , C07D407/14
摘要： A compound of formula la: (Ia) The present invention relates to novel indazolyl derivatives, to pharmaceutical compositions comprising such derivatives, to processes for preparing such novel derivatives and to the use of such derivatives as medicaments.

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