专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

11. 发明申请

WO2009073508A3 POLYSACCHARIDE GEL COMPOSITIONS AND METHODS FOR SUSTAINED DELIVERY OF DRUGS 审中-公开
标题翻译：多糖凝胶组合物和用于持续递送药物的方法
公开(公告)号：WO2009073508A3
公开(公告)日：2009-08-13
申请号：PCT/US2008084841
申请日：2008-11-26
申请人： ALLERGAN INC , TEZEL AHMET , ROBINSON MICHAEL R
发明人： TEZEL AHMET , ROBINSON MICHAEL R
IPC分类号： A61K8/73 , A61K9/10 , A61K31/715 , A61K47/36 , A61P27/02
CPC分类号： A61K47/4823 , A61K8/042 , A61K8/73 , A61K8/733 , A61K8/735 , A61K8/736 , A61K9/0095 , A61K31/58 , A61K31/715 , A61K47/61 , A61K47/6903
摘要： Methods of producing a biocompatible polysaccharide gel composition having sustained release properties are disclosed. Also disclosed is a biocompatible polysaccharide gel composition having sustained release properties, a method of treating a disease or condition using the present biocompatible polysaccharide gel composition, and a method of controlling rate of release of at least one target solute from the biocompatible polysaccharide gel composition. Pharmaceutical compositions which include the present biocompatible polysaccharide gel composition also are disclosed.
摘要翻译：公开了生产具有缓释性能的生物相容性多糖凝胶组合物的方法。还公开了具有持续释放性质的生物相容性多糖凝胶组合物，使用本发明的生物相容性多糖凝胶组合物治疗疾病或病症的方法，以及控制至少一种目标溶质从生物相容性多糖凝胶组合物中释放速率的方法。还公开了包含本发明的生物相容性多糖凝胶组合物的药物组合物。

12. 发明申请

WO2009073508A2 POLYSACCHARIDE GEL COMPOSITIONS AND METHODS FOR SUSTAINED DELIVERY OF DRUGS 审中-公开
标题翻译：多糖凝胶组合物和用于持续输送药物的方法
公开(公告)号：WO2009073508A2
公开(公告)日：2009-06-11
申请号：PCT/US2008/084841
申请日：2008-11-26
申请人： ALLERGAN, INC. , TEZEL, Ahmet , ROBINSON, Michael, R.
发明人： TEZEL, Ahmet , ROBINSON, Michael, R.
IPC分类号： C08B37/00 , C08B37/10 , C08B37/08 , C08B37/04 , A61K47/36 , A61K31/58 , A61K8/73 , A61K9/10 , A61K31/715 , A61P27/02
CPC分类号： A61K47/4823 , A61K8/042 , A61K8/73 , A61K8/733 , A61K8/735 , A61K8/736 , A61K9/0095 , A61K31/58 , A61K31/715 , A61K47/61 , A61K47/6903
摘要： Methods of producing a biocompatible polysaccharide gel composition having sustained release properties are disclosed. Also disclosed is a biocompatible polysaccharide gel composition having sustained release properties, a method of treating a disease or condition using the present biocompatible polysaccharide gel composition, and a method of controlling rate of release of at least one target solute from the biocompatible polysaccharide gel composition. Pharmaceutical compositions which include the present biocompatible polysaccharide gel composition also are disclosed.
摘要翻译：公开了具有持续释放特性的生物相容性多糖凝胶组合物的制备方法。还公开了具有持续释放性质的生物相容性多糖凝胶组合物，使用本生物相容性多糖凝胶组合物治疗疾病或病症的方法，以及从生物相容性多糖凝胶组合物中控制至少一种靶溶质释放速率的方法。还公开了包含本发明的生物相容性多糖凝胶组合物的药物组合物。

13. 发明申请

WO2012125698A1 SELF-ADJUSTING GASTRIC BAND HAVING VARIOUS COMPLIANT COMPONENTS AND/OR SATIETY BOOSTER 审中-公开
标题翻译：自调整带有各种合身部件和/或安心推杆
公开(公告)号：WO2012125698A1
公开(公告)日：2012-09-20
申请号：PCT/US2012/029036
申请日：2012-03-14
申请人： ALLERGAN, INC. , SNOW, Sean , BORRELL, Marcos , TEZEL, Ahmet , O'BRIEN, Paul
发明人： SNOW, Sean , BORRELL, Marcos , TEZEL, Ahmet , O'BRIEN, Paul
IPC分类号： A61F5/00 , A61B5/00
CPC分类号： A61F5/0056
摘要： In some embodiments, the present invention generally provides self-adjusting gastric banding systems (1100) for the treatment of obesity and obesity related conditions, as well as systems for allowing the automatic self - adjustment of gastric bands when a patient swallows a large bolus. In some embodiments, the present invention generally provides for gastric banding systems having a satiety booster (1117), for example, to increase satiety levels when a patient desires to curb appetite at a particular time. In some embodiments, the present invention may provide for gastric banding systems that allow for both the automatic self - adjustment of gastric bands when a patient swallows a large bolus and an incorporated satiety booster for increasing satiety levels when a patient desires to curb appetite at a particular time.
摘要翻译：在一些实施方案中，本发明通常提供用于治疗肥胖和肥胖相关病症的自调节胃束带系统（1100），以及当患者吞咽大量推注时允许胃束带自动自我调节的系统。在一些实施方案中，本发明通常提供具有饱腹感增强剂（1117）的胃束带系统，例如当患者希望在特定时间遏制食欲时增加饱腹感水平。在一些实施方案中，本发明可以提供胃束带系统，当患者吞咽大量推注时，允许胃束带的自动自我调节，并且当患者希望在一个患者期望遏制食欲时，增加饱和感觉增强剂特定的时间。

14. 发明申请

WO2012054752A1 TUNABLY CROSSLINKED POLYSACCHARIDE COMPOSITIONS 审中-公开
标题翻译： TUNABLY交联多糖组合物
公开(公告)号：WO2012054752A1
公开(公告)日：2012-04-26
申请号：PCT/US2011/057137
申请日：2011-10-20
申请人： ALLERGAN, INC. , STROUMPOULIS, Dimitrios , TEZEL, Ahmet
发明人： STROUMPOULIS, Dimitrios , TEZEL, Ahmet
IPC分类号： A61L27/20 , A61L27/52 , A61L27/58
CPC分类号： A61L27/20 , A61L27/52 , A61L2400/06 , A61L2430/34 , C08B37/0072 , C08J3/075 , C08J2305/08 , C08L5/08
摘要： The present specification generally relates to injectable dermal fillers including multifunctional polyethylene glycol-based crosslinking agents, hydrogel compositions comprising a matrix polymer crosslinked with such crosslinking agents, and methods of treating a soft tissue condition using such hydrogel compositions.
摘要翻译：本说明书通常涉及可注射的真皮填料，包括多官能聚乙二醇基交联剂，包含与这种交联剂交联的基质聚合物的水凝胶组合物，以及使用这种水凝胶组合物治疗软组织病症的方法。

15. 发明申请

WO2011119468A1 POLYSACCHARIDE AND PROTEIN-POLYSACCHARIDE CROSS-LINKED HYDROGELS FOR SOFT TISSUE AUGMENTATION 审中-公开
标题翻译：用于软组织补充剂的多糖和蛋白多糖交联氢化物
公开(公告)号：WO2011119468A1
公开(公告)日：2011-09-29
申请号：PCT/US2011/029150
申请日：2011-03-21
申请人： ALLERGAN, INC. , GUILLEN, Karina, Heredia , TEZEL, Ahmet
发明人： GUILLEN, Karina, Heredia , TEZEL, Ahmet
IPC分类号： A61L27/20 , A61L27/50 , A61L27/52
CPC分类号： A61L27/26 , A61K47/36 , A61K47/42 , A61L27/20 , A61L27/24 , A61L27/52 , A61L27/54 , A61L2300/402 , A61L2300/404 , A61L2300/41 , A61L2300/426 , A61L2300/43 , A61L2300/434 , A61L2300/442 , C08L5/08 , C08L89/06
摘要： Disclosed herein are cohesive soft tissue fillers, for example, dermal and subdermal fillers, based on hyaluronic acids and optionally including proteins. In one aspect, hyaluronic acid-based compositions described herein include zero-length cross-linked moieties and optionally at least one active agent. The present hyaluronic acid-based compositions have enhanced flow characteristics, hardness, and persistence compared to known hyaluronic acid-based compositions. Methods and processes of preparing such hyaluronic acid-based compositions are also provided.
摘要翻译：本文公开了基于透明质酸和任选地包括蛋白质的粘性软组织填充剂，例如真皮和皮下填充剂。一方面，本文所述的基于透明质酸的组合物包括零长度交联部分和任选的至少一种活性剂。与已知的基于透明质酸的组合物相比，本发明的透明质酸组合物具有增强的流动特性，硬度和持久性。还提供了制备这种基于透明质酸的组合物的方法和方法。

16. 发明申请

WO2011100450A1 REMOTELY ADJUSTABLE GASTRIC BANDING SYSTEM 审中-公开
标题翻译：远程可调节的带式系统
公开(公告)号：WO2011100450A1
公开(公告)日：2011-08-18
申请号：PCT/US2011/024375
申请日：2011-02-10
申请人： ALLERGAN, INC. , BIRK, Janel , LESLIE, Dustin , SNOW, Sean , TEZEL, Ahmet
发明人： BIRK, Janel , LESLIE, Dustin , SNOW, Sean , TEZEL, Ahmet
IPC分类号： A61F5/00
CPC分类号： A61F5/0056 , A61F5/003 , A61F5/0059
摘要： An implantable device comprises a reservoir for holding a fluid and a sensor positioned between the gastric band and the reservoir. The sensor monitors a parameter of the fluid when filling and draining the inflatable portion of the gastric band. A first flow control device controls a flow of the fluid when filling and draining the inflatable portion of the gastric band. A pumping device moves the fluid into and out of the inflatable portion of the gastric band, and the pumping device is capable of being activated and deactivated using a telemetric signal received from a remote device.
摘要翻译：可植入装置包括用于保持流体的储存器和位于胃带和储存器之间的传感器。当填充和排空胃带的可充气部分时，传感器监测流体的参数。第一流量控制装置在填充和排出胃束带的可充气部分时控制流体的流动。泵送装置将流体移入和移出胃束带的可膨胀部分，并且泵送装置能够使用从远程装置接收到的遥测信号被激活和去激活。

17. 发明申请

WO2011022235A3 REINFORCED PROSTHETIC IMPLANT WITH FLEXIBLE SHELL 审中-公开
公开(公告)号：WO2011022235A3
公开(公告)日：2011-02-24
申请号：PCT/US2010/044896
申请日：2010-08-09
申请人： ALLERGAN, INC. , SCHUESSLER, David, J. , TEZEL, Ahmet
发明人： SCHUESSLER, David, J. , TEZEL, Ahmet
IPC分类号： A61L27/18 , A61F2/12 , A61L27/50
摘要： A fluid-filled soft prosthetic implant having a shell with a reinforced shell wall. The soft prosthetic implant may be for breast reconstruction or augmentation, or to restore the normal appearance of soft tissue in the buttocks, chin, calf, etc. The implants may be reinforced using several methods: reinforcement of the shell wall, non-homogeneous gel-filling, or both. At least a portion of the perimeter region desirably has a shell wall thickness greater than the average shell wall thickness of either the anterior face or the posterior face. The added material at the perimeter region strengthens that area in which a large percentage of implant ruptures occur. The reinforced perimeter also helps prevent the implant from collapsing or folding, which can cause undesirable rippling or wrinkling visible through the patient's skin. The remainder of the shell will desirably have a nominal wall thickness to retain the overall softness and supple feel of the implant. The implant shell may be filled with gels of different gel cohesiveness to counterbalance any reinforced area or to provide added reinforcement.

18. 发明申请

WO2011022235A2 REINFORCED PROSTHETIC IMPLANT WITH FLEXIBLE SHELL 审中-公开
标题翻译：带有柔韧外壳的加强人造血管植入物
公开(公告)号：WO2011022235A2
公开(公告)日：2011-02-24
申请号：PCT/US2010044896
申请日：2010-08-09
申请人： ALLERGAN INC , SCHUESSLER DAVID J , TEZEL AHMET
发明人： SCHUESSLER DAVID J , TEZEL AHMET
IPC分类号： A61L27/02
CPC分类号： A61F2/12 , A61F2240/001 , A61L27/18 , A61L27/26 , A61L27/50 , A61L2430/04 , B29C41/04 , B29C41/22 , B29K2083/00 , B29L2031/7532 , C08L83/04
摘要： A fluid-filled soft prosthetic implant having a shell with a reinforced shell wall. The soft prosthetic implant may be for breast reconstruction or augmentation, or to restore the normal appearance of soft tissue in the buttocks, chin, calf, etc. The implants may be reinforced using several methods: reinforcement of the shell wall, non-homogeneous gel-filling, or both. At least a portion of the perimeter region desirably has a shell wall thickness greater than the average shell wall thickness of either the anterior face or the posterior face. The added material at the perimeter region strengthens that area in which a large percentage of implant ruptures occur. The reinforced perimeter also helps prevent the implant from collapsing or folding, which can cause undesirable rippling or wrinkling visible through the patient's skin. The remainder of the shell will desirably have a nominal wall thickness to retain the overall softness and supple feel of the implant. The implant shell may be filled with gels of different gel cohesiveness to counterbalance any reinforced area or to provide added reinforcement.
摘要翻译：一种流体填充的软性假体植入物，其具有带有加强壳壁的壳体。软性假体植入物可以用于乳房再造或隆起，或恢复臀部，下巴，小腿等中的软组织的正常外观。可以使用几种方法来增强植入物：加强壳壁，不均匀凝胶填充，或两者兼而有之。希望周边区域的至少一部分的壳壁厚度大于前表面或后表面的平均壳壁厚度。在周边区域添加的材料增强了大部分植入物破裂出现的区域。加强的周边也有助于防止植入物塌陷或折叠，这可能会导致通过患者皮肤看到不希望的波纹或起皱。壳体的其余部分将理想地具有标称壁厚以保持植入物的整体柔软度和柔软感。植入物外壳可以填充有不同凝胶粘结性的凝胶以平衡任何加固区域或提供附加的加固。

19. 发明申请

WO2008147817A2 COATED HYALURONIC ACID PARTICLES 审中-公开
标题翻译：涂覆的羟丙酸颗粒
公开(公告)号：WO2008147817A2
公开(公告)日：2008-12-04
申请号：PCT/US2008/064378
申请日：2008-05-21
申请人： ALLERGAN, INC. , CHAMPION, Julie, A. , MITRAGOTRI, Samir , TEZEL, Ahmet
发明人： CHAMPION, Julie, A. , MITRAGOTRI, Samir , TEZEL, Ahmet
IPC分类号： A61L27/20 , A61L27/58 , A61K9/16 , A61K31/728
CPC分类号： A61L27/20 , A61K9/0019 , A61K9/5031 , A61K9/5036 , A61K9/5052 , A61K31/728 , A61L27/58 , A61L2430/34
摘要： The present invention generally relates to particles comprising hyaluronic acid, wherein the particles are coated or encapsulated with a coating. The coating preferably comprises a polymer, protein, polysaccharide, or combination thereof that decreases the rate of degradation of the hyaluronic acid once the particles are placed in an aqueous environment, such as inside mammalian skin. The compositions of the present invention comprising such coated hyaluronic acid are useful for soft tissue augmentation, and are particularly useful as dermal fillers.
摘要翻译：本发明一般涉及包含透明质酸的颗粒，其中颗粒被涂层包被或包封。涂层优选包含聚合物，蛋白质，多糖或其组合，其一旦将颗粒置于水性环境（例如哺乳动物皮肤内）中，则降低透明质酸的降解速率。包含这种涂覆的透明质酸的本发明的组合物可用于软组织增加，并且特别可用作皮肤填充剂。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式