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    • 9. 发明授权
    • Spectral monitoring of ingredient blending
    • 成分混合光谱监测
    • US08967851B1
    • 2015-03-03
    • US13353872
    • 2012-01-19
    • Gabor J. Kemeny
    • Gabor J. Kemeny
    • B01F15/00B01F15/06
    • B01F15/00253B01F7/00908B01F7/02B01F9/005B01F9/02B01F15/00214G01J2003/2826G01N21/359G01N21/65G01N2021/6417
    • Spectral and hyperspectral imaging systems allow monitoring of pharmaceutical or other industrial blending processes to establish the characteristics of the blend. To illustrate, a batch type blender may be equipped with a computer controlled drive mechanism that is slowed down at a predetermined point during rotation to assess the progress of the blending through an imaging window mounted on the blender. A fast hyperspectral imaging device can be provided directly on the blender to view the blend through the imaging window, or can be placed in a fixed position relative to the rotating blender. The image of the blend is preferably captured line-by-line at a location at or near the bottom of the blender synchronously with the blender's rotation. The spectral information acquired from the blend at each rotation can be used to assess whether the nominal blend composition is achieved, or to reveal uniformity of the blend.
    • 光谱和高光谱成像系统允许监测药物或其他工业混合过程以建立混合物的特征。 为了说明,批式混合器可以配备有计算机控制的驱动机构,其在旋转期间在预定点被减速以通过安装在搅拌器上的成像窗口评估混合的进度。 可以直接在混合器上提供快速超光谱成像装置,以通过成像窗口观看混合物,或者可以将其放置在相对于旋转搅拌机的固定位置。 混合物的图像优选在与搅拌器旋转同步的位于搅拌器底部或其附近的位置处逐条捕获。 在每次旋转时从共混物获取的光谱信息可用于评估标称共混物组合物是否达到,或显示共混物的均匀性。