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1. 发明申请

US20050004041A1 Novel peptide having angiotensin convertase inibitory effect 有权
标题翻译：新型肽具有血管紧张素转化酶的内在作用
公开(公告)号：US20050004041A1
公开(公告)日：2005-01-06
申请号：US10496200
申请日：2002-11-21
申请人： Yoshitaka Tamura , Hiroshi Miyakawa , Akio Yamada , Hitoshi Saito , Yasushi Kawaguchi , Hiroshi Ochi , Tomoko Ide , Eri Inoue
发明人： Yoshitaka Tamura , Hiroshi Miyakawa , Akio Yamada , Hitoshi Saito , Yasushi Kawaguchi , Hiroshi Ochi , Tomoko Ide , Eri Inoue
IPC分类号： A61K38/00 , A61P9/00 , A61P9/12 , A61P43/00 , C07K5/083 , C07K14/47 , C07K5/06 , A61K38/05
CPC分类号： C07K14/4732 , A61K38/00 , C07K5/081
摘要： A peptide Met-Lys-Pro, which is obtained by chemical synthesis ot hydrolysis of casein, is used as the active ingredient of angiotensin converting enzyme inhibitors or hypotensive drugs.
摘要翻译：用酪蛋白水解化学合成获得的肽Met-Lys-Pro作为血管紧张素转换酶抑制剂或降血压药物的有效成分。

2. 发明授权

US07022676B2 Peptide having angiotensin converting enzyme inhibitory effect 有权
标题翻译：肽具有血管紧张素转换酶的抑制作用
公开(公告)号：US07022676B2
公开(公告)日：2006-04-04
申请号：US10496200
申请日：2002-11-21
申请人： Yoshitaka Tamura , Hiroshi Miyakawa , Akio Yamada , Hitoshi Saito , Yasushi Kawaguchi , Hiroshi Ochi , Tomoko Ide , Eri Inoue
发明人： Yoshitaka Tamura , Hiroshi Miyakawa , Akio Yamada , Hitoshi Saito , Yasushi Kawaguchi , Hiroshi Ochi , Tomoko Ide , Eri Inoue
IPC分类号： A61K38/00
CPC分类号： C07K14/4732 , A61K38/00 , C07K5/081
摘要： A peptide Met-Lys-Pro, which is obtained by chemical synthesis ot hydrolysis of casein, is used as the active ingredient of angiotensin converting enzyme inhibitors or hypotensive drugs.
摘要翻译：用酪蛋白水解化学合成获得的肽Met-Lys-Pro作为血管紧张素转换酶抑制剂或降血压药物的有效成分。

3. 发明授权

US06395508B1 Peptide mixture and products thereof 失效
标题翻译：肽混合物及其产物
公开(公告)号：US06395508B1
公开(公告)日：2002-05-28
申请号：US09316957
申请日：1999-05-24
申请人： Seiichi Shimamura , Yoshitaka Tamura , Hiroshi Miyakawa , Hitoshi Saito , Yasushi Kawaguchi , Naoko Isomura , Yoko Akazome , Hiroshi Ochi , Mihoko Kawamoto
发明人： Seiichi Shimamura , Yoshitaka Tamura , Hiroshi Miyakawa , Hitoshi Saito , Yasushi Kawaguchi , Naoko Isomura , Yoko Akazome , Hiroshi Ochi , Mihoko Kawamoto
IPC分类号： A23C2102
CPC分类号： A61K38/018 , A23J3/08 , A23J3/343 , A23L33/18 , A61K38/01 , Y10S530/833
摘要： A method for producing a peptide mixture from a starting protein by (1) adding at least one protease to an aqueous solution of at least one starting protein to hydrolyse the starting protein, (2) measuring the amount of a free amino acid selected from the group consisting of lysine, phenylalanine, leucine and arginine produced during the hydrolysis of the starting protein, (3) calculating the amount of the free amino acid with respect to the total amount of amino acid contained in the starting protein, and (4) terminating the hydrolysis when the calculated amount of the free amino acid with respect to the total amount of the amino acid contained in the starting protein falls within a predetermined range. The inventive method provides a starting protein hydrolysate of uniform and consistent quality.
摘要翻译：（1）在至少一种起始蛋白质的水溶液中加入至少一种蛋白酶以水解起始蛋白质的方法，从起始蛋白质制备肽混合物的方法，（2）测量游离氨基酸的量在起始蛋白水解期间产生的赖氨酸，苯丙氨酸，亮氨酸和精氨酸组成的组，（3）计算游离氨基酸相对于起始蛋白质中所含氨基酸总量的量，以及（4）终止当游离氨基酸的计算量相对于起始蛋白质中含有的氨基酸总量的计算量落在预定范围内时，水解。本发明的方法提供均匀且一致质量的起始蛋白质水解产物。

4. 发明授权

US5952193A Peptide mixture and products thereof 失效
标题翻译：肽混合物及其产物
公开(公告)号：US5952193A
公开(公告)日：1999-09-14
申请号：US817095
申请日：1997-04-14
申请人： Seiichi Shimamura , Yoshitaka Tamura , Hiroshi Miyakawa , Hitoshi Saito , Yasushi Kawaguchi , Naoko Isomura , Yoko Akazome , Hiroshi Ochi , Mihoko Kawamoto
发明人： Seiichi Shimamura , Yoshitaka Tamura , Hiroshi Miyakawa , Hitoshi Saito , Yasushi Kawaguchi , Naoko Isomura , Yoko Akazome , Hiroshi Ochi , Mihoko Kawamoto
IPC分类号： A23J3/08 , A23J3/34 , A23L1/305 , A61K38/01 , A23C21/02 , A23C21/04 , A23C21/06
CPC分类号： A61K38/018 , A23J3/08 , A23J3/343 , A23L33/18 , A61K38/01 , Y10S530/833
摘要： A method for producing a peptide mixture from whey protein by (1) adding at least one protease to an aqueous solution of at least one whey protein to hydrolyze the whey protein, (2) measuring the amount of a free amino acid selected from the group consisting of lysine, phenylalanine, leucine and arginine produced during the hydrolysis of the whey protein, (3) calculating the amount of the free amino acid with respect to the total amount of the amino acid contained in the whey protein, and (4) terminating the hydrolysis when the calculated amount of the free amino acid with respect to the total amount of the amino acid contained in the whey protein falls within a predetermined range. The inventive method provides a whey protein hydrolysate of consistent quality.
摘要翻译： PCT No.PCT / JP95 / 02109 Sec。 371日期1997年04月14日 102（e）1997年4月14日PCT 1995年10月13日PCT PCT。公开号WO96 / 11584 日期：1996年04月25日（一）通过（1）向至少一种乳清蛋白的水溶液中加入至少一种蛋白酶以水解乳清蛋白，从乳清蛋白制备肽混合物的方法，（2）测量游离氨基选自在乳清蛋白水解期间产生的赖氨酸，苯丙氨酸，亮氨酸和精氨酸的酸，（3）计算游离氨基酸相对于乳清蛋白中所含氨基酸总量的量，和（4）当游离氨基酸的计算量相对于乳清蛋白中所含氨基酸总量的计算量落在预定范围内时，终止水解。本发明的方法提供了质量一致的乳清蛋白水解产物。

5. 发明申请

US20070031506A1 Interleukin-18 inducer 审中-公开
标题翻译：白细胞介素-18诱导物
公开(公告)号：US20070031506A1
公开(公告)日：2007-02-08
申请号：US11580173
申请日：2006-10-12
申请人： Hirotoshi Hayasawa , Yoshitaka Tamura , Hiroshi Miyakawa , Akio Yamada , Tetsuya Kuhara , Hiroshi Ochi
发明人： Hirotoshi Hayasawa , Yoshitaka Tamura , Hiroshi Miyakawa , Akio Yamada , Tetsuya Kuhara , Hiroshi Ochi
IPC分类号： C12P21/06 , A61K35/20
CPC分类号： A61K38/018
摘要： Whey protein is hydrolyzed with hydrolase so that a rate of hydrolysis is preferably 20 to 30%. A fraction, which has molecular weights above 10,000 daltons, is removed from a resultant hydrolysate by means of an ultrafiltration method to obtain a whey protein hydrolysate which is used as an active ingredient of an interleukin-18 inducer.
摘要翻译：乳清蛋白用水解酶水解，水解速率优选为20〜30％。通过超滤方法从所得水解产物中除去分子量高于10,000道尔顿的级分，得到用作白细胞介素-18诱导剂活性成分的乳清蛋白水解产物。

6. 发明授权

US5744179A Low-phosphorus whey protein, manufacturing method thereof, low-phosphorus purified whey hydrolysate and manufacturing method thereof 失效
标题翻译：低磷乳清蛋白及其制备方法，低磷纯化乳清水解物及其制备方法
公开(公告)号：US5744179A
公开(公告)日：1998-04-28
申请号：US428129
申请日：1995-09-06
申请人： Seiichi Shimamura , Yoshitaka Tamura , Teruhiko Mizota , Yasushi Kawaguchi , Yoko Nagasako , Hiroshi Ochi
发明人： Seiichi Shimamura , Yoshitaka Tamura , Teruhiko Mizota , Yasushi Kawaguchi , Yoko Nagasako , Hiroshi Ochi
IPC分类号： A23J1/20 , A23J3/34 , A23C9/146
CPC分类号： C12Y304/00 , A23J1/205 , A23J3/343 , A23V2002/00
摘要： A whey protein having a phosphorus content reduced to below 0.15 mg per gram of protein, a manufacturing method thereof, a low-phosphorus hydrolysate highly purified having a low phosphorus content. The method comprises the steps of adjusting pH of the solution containing the whey protein to below 4, and contacting the solution with a cation exchange resin, sequentially contacting the solution with an anion exchange resin, thereby reducing the phosphorus content to below 0.15 mg per gram of protein, and the highly purified low-phosphorus whey protein hydrolysate of the present invention is available by hydrolyzing the above-mentioned low-phosphorus whey protein with proteases.
摘要翻译： PCT No.PCT / JP93 / 01729 Sec。 371日期：1995年9月6日 102（e）日期1995年9月6日PCT提交1993年11月26日PCT公布。公开号WO94 / 12053 日期：1995年6月9日具有磷含量降低至低于0.15mg /克蛋白质的乳清蛋白，其制造方法，具有低磷含量的高度纯化的低磷水解产物。该方法包括以下步骤：将含有乳清蛋白的溶液的pH调节至4以下，并使该溶液与阳离子交换树脂接触，依次使该溶液与阴离子交换树脂接触，从而将磷含量降低至低于0.15mg /克的蛋白质，通过用蛋白酶水解上述低磷乳清蛋白，可获得本发明的高纯度低磷乳清蛋白水解产物。

7. 发明申请

US20120263839A1 METHOD FOR MANUFACTURING LOW-PHOSPHORUS WHEY 有权
标题翻译：制造低磷白蛋白的方法
公开(公告)号：US20120263839A1
公开(公告)日：2012-10-18
申请号：US13497646
申请日：2010-09-24
申请人： Nobuo Seki , Masatoshi Ohnishi , Kie Kinoshita , Yoshitaka Tamura , Hitoshi Saito , Hiroshi Ochi , Takafumi Kimura
发明人： Nobuo Seki , Masatoshi Ohnishi , Kie Kinoshita , Yoshitaka Tamura , Hitoshi Saito , Hiroshi Ochi , Takafumi Kimura
IPC分类号： A23C21/00
CPC分类号： A23C9/1425 , A23C9/146 , A23J3/08 , A23L33/40 , A23V2002/00 , A23V2250/54252 , A23V2300/30 , A23V2300/34
摘要： A method of manufacturing a low-phosphorus whey, the method including subjecting a raw whey liquid to a demineralization treatment using a nanofiltration method to obtain a low-chloride whey liquid in which the chloride content has been reduced to not more than 30 mmol per 100 g of solids, and passing the low-chloride whey liquid through an ion exchange resin to obtain an ion-exchanged whey liquid having a reduced phosphorus content, wherein the ion exchange resin is composed of an anion exchange resin, and at least an anion exchange resin in chloride form is used as the anion exchange resin. The method of manufacturing a low-phosphorus whey can reduce the phosphorus content within the whey while suppressing reduction in the calcium and magnesium content.
摘要翻译：一种低磷乳清的制造方法，其特征在于，使用纳滤法对原料乳清液进行脱盐处理，得到氯化物含量降低至不足30mmol / L以下的低氯化物乳清液 g的固体，并使低氯化物乳清液通过离子交换树脂，得到具有降低的磷含量的离子交换乳清液，其中所述离子交换树脂由阴离子交换树脂构成，并且至少阴离子交换使用氯化物形式的树脂作为阴离子交换树脂。制备低磷乳清的方法可以降低乳清中的磷含量，同时抑制钙和镁含量的降低。

8. 发明授权

US08795750B2 Method for manufacturing low-phosphorus whey 有权
标题翻译：低磷乳清制备方法
公开(公告)号：US08795750B2
公开(公告)日：2014-08-05
申请号：US13497646
申请日：2010-09-24
申请人： Nobuo Seki , Masatoshi Ohnishi , Kie Kinoshita , Yoshitaka Tamura , Hitoshi Saito , Hiroshi Ochi , Takafumi Kimura
发明人： Nobuo Seki , Masatoshi Ohnishi , Kie Kinoshita , Yoshitaka Tamura , Hitoshi Saito , Hiroshi Ochi , Takafumi Kimura
IPC分类号： A23C9/14 , A23C9/142 , A23C9/146 , A23J3/08 , A23L1/29
CPC分类号： A23C9/1425 , A23C9/146 , A23J3/08 , A23L33/40 , A23V2002/00 , A23V2250/54252 , A23V2300/30 , A23V2300/34
摘要： A method of manufacturing a low-phosphorus whey, the method including subjecting a raw whey liquid to a demineralization treatment using a nanofiltration method to obtain a low-chloride whey liquid in which the chloride content has been reduced to not more than 30 mmol per 100 g of solids, and passing the low-chloride whey liquid through an ion exchange resin to obtain an ion-exchanged whey liquid having a reduced phosphorus content, wherein the ion exchange resin is composed of an anion exchange resin, and at least an anion exchange resin in chloride form is used as the anion exchange resin. The method of manufacturing a low-phosphorus whey can reduce the phosphorus content within the whey while suppressing reduction in the calcium and magnesium content.
摘要翻译：一种低磷乳清的制造方法，其特征在于，使用纳滤法对原料乳清液进行脱盐处理，得到氯化物含量降低至不足30mmol / L以下的低氯化物乳清液 g的固体，并使低氯化物乳清液通过离子交换树脂，得到具有降低的磷含量的离子交换乳清液，其中所述离子交换树脂由阴离子交换树脂构成，并且至少阴离子交换使用氯化物形式的树脂作为阴离子交换树脂。制备低磷乳清的方法可以降低乳清中的磷含量，同时抑制钙和镁含量的降低。

9. 发明申请

US20060188606A1 Process for producing cheese 审中-公开
标题翻译：生产奶酪的方法
公开(公告)号：US20060188606A1
公开(公告)日：2006-08-24
申请号：US10548927
申请日：2004-04-27
申请人： Kiyotaka Takahashi , Kiyotaka Miyauchi , Rei Mizuno , Hiroshi Miyakawa , Hiroshi Ochi
发明人： Kiyotaka Takahashi , Kiyotaka Miyauchi , Rei Mizuno , Hiroshi Miyakawa , Hiroshi Ochi
IPC分类号： A23C9/12
CPC分类号： A23C19/0684 , A23C19/06 , A23C19/08 , A23C19/0912 , A23C2250/052 , A23C2250/054
摘要： A cheese production process of the present invention includes stretching cheese curds in hot water and contacting the cheese curds and a texture modifier capable of binding or adsorbing calcium either before or simultaneously with the stretching so as to enable the obtaining of cheese having a preferable rice cake-like elastic texture by improving the gum-like adhesive texture, hard rubber-like chewiness, and residual particles in the mouth when eating after baking, of cheese that is produced by going through a step of stretching cheese curds in hot water.
摘要翻译：本发明的奶酪生产方法包括在热水中拉伸干酪凝乳并使奶酪凝乳和能够在拉伸之前或同时结合或吸附钙的纹理调节剂接触，以便获得具有优选米糕的奶酪通过改善胶状粘合剂质地，硬橡胶状咀嚼性和在烘烤后进食时口中残留颗粒的类似弹性织构，通过在热水中拉伸干酪凝乳的步骤产生的奶酪。

10. 发明授权

US07580763B2 Recording apparatus for recording signal including a plurality of sound information 失效
标题翻译：用于记录包括多个声音信息的信号的记录装置
公开(公告)号：US07580763B2
公开(公告)日：2009-08-25
申请号：US11254284
申请日：2005-10-20
申请人： Hiroshi Ochi
发明人： Hiroshi Ochi
IPC分类号： G06F17/00
CPC分类号： H04N5/76 , G11B27/034 , G11B27/28 , H04N5/781 , H04N9/8205 , H04N9/8227
摘要： A first sound signal includes a first kind of sound signals and a second kind of sound signals. Chapter numbers are added to the first sound signal for respective switching of the kind of the sound. A second sound signal indicates a resulting sound signal after deletion of the second kind of sound signals from the first sound signal. A third sound signal indicates a sound signal in which remaining portions after deletion of the second kind of sound signals are combined with each other and chapter numbers are newly set. As described above, a chapter corresponding to a kind of a sound signal is added when the kind of the sound signal is switched, and a received signal is edited based on the chapter.
摘要翻译：第一声音信号包括第一种声音信号和第二种声音信号。将第一声音信号加到第一声音信号上，以便各种切换声音。第二声音信号表示在从第一声音信号中删除第二类声音信号之后产生的声音信号。第三声音信号表示将第二种声音信号删除之后的剩余部分相互组合的声音信号，并且重新设定章节编号。如上所述，当切换声音信号的种类时，添加与声音信号的种类对应的章节，并且基于该章节编辑接收信号。

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