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1. 发明授权

US09993009B2 Dry milk formula and method and system for preparing same 有权
公开(公告)号：US09993009B2
公开(公告)日：2018-06-12
申请号：US14782130
申请日：2014-04-03
申请人： N.V. Nutricia
发明人： John Tobin , Jitti Chiaranaipanich , Rudolph Eduardus Maria Verdurmen , Antonius Hendricus Janssen , Olivier Bertrand Rabartin , Raoul Charles Johan Moonen , Martijn Johannes Van Der Hoeven
IPC分类号： A23C9/15 , A23L1/29 , A23C1/12 , A23C9/142 , A23C9/144 , A23C9/146 , A23C1/00 , A23L33/00
CPC分类号： A23C9/1512 , A23C1/00 , A23C1/12 , A23C9/1422 , A23C9/1425 , A23C9/144 , A23C9/146 , A23L33/40 , A23V2002/00
摘要： A process and system is shown for obtaining a dry milk formula, having (a-i) ultrafiltration of an animal skim milk composition having 70-90 wt % casein and 10-30 wt % whey proteins, based on total protein, and (a-ii) ultrafiltration of an animal whey composition having 0-25 wt % casein and 75-100 wt % whey proteins, based on total protein; or (a-iii) ultrafiltration of a mixture of the compositions of (a-i) and (a-ii), (b) removing polyvalent ions from the UF permeate originating from step (a-i) and/or (a-ii) or (a-iii) to obtain at least one softened UF permeate; (c) combining the at least one softened UF permeate with a UF retentate to obtain a combined product; and (d) drying the combined product to obtain a dry milk formula.

2. 发明申请

US20170027989A1 Compositions and Methods for the Prevention and Treatment of Metabolic Diseases 审中-公开
标题翻译：用于预防和治疗代谢疾病的组合物和方法
公开(公告)号：US20170027989A1
公开(公告)日：2017-02-02
申请号：US15058452
申请日：2016-03-02
申请人： Rajan V. Vembu
发明人： Rajan V. Vembu
IPC分类号： A61K35/20 , A23C9/142 , A23K20/147 , A61K38/02 , A23K50/42 , A23K50/75 , A23K50/70 , A23L33/19 , A23C9/146 , A23K50/20
CPC分类号： A61K35/20 , A23C9/1425 , A23C9/1427 , A23C9/146 , A23K10/28 , A23K20/147 , A23K50/20 , A23K50/42 , A23K50/70 , A23K50/75 , A23L33/19 , A23V2002/00 , A61K33/00 , A61K38/018 , A61K38/02 , A61K45/06 , Y02P60/875 , A61K2300/00
摘要： The present invention is a new method and composition that enhance bone repair, formation, maintenance and slowing of bone resorption. The present invention relates to methods and compositions that enhance collagen formation, tendon health and tendon injury healing, bone maintenance and bone injury healing, and the prevention and treatment of metabolic diseases. The present invention is a part of the therapy to maintain bone health among patients with diabetic bone resorption and others with metabolic disorders. In one embodiment, the composition is a composite of hydroxyapatite and an organic matrix composed of milk pH-dependent serum proteins, i.e., bone morphogenic proteins (BMP), milk serum-derived specific proteins (MSSP), and milk serum derived proteins.
摘要翻译：本发明是增强骨修复，形成，维持和减缓骨吸收的新方法和组合物。本发明涉及增强胶原蛋白形成，肌腱健康和肌腱损伤愈合，骨维持和骨损伤愈合以及预防和治疗代谢性疾病的方法和组合物。本发明是维持患有糖尿病骨吸收的患者和具有代谢紊乱的其它患者的骨骼健康的治疗的一部分。在一个实施方案中，组合物是由乳酸pH依赖性血清蛋白，即骨形态发生蛋白（BMP），乳清血清特异蛋白（MSSP）和乳清血清衍生蛋白质组成的羟基磷灰石和有机基质的复合物。

3. 发明授权

US08840947B2 Whey or raw milk demineralisation and fractionation 有权
$Whey or raw milk demineralisation and fractionation$
标题翻译：乳清或生牛奶去矿化和分馏
公开(公告)号：US08840947B2
公开(公告)日：2014-09-23
申请号：US13257217
申请日：2010-03-17
申请人： Stephen Niall Scott , Ashok Krishnapillai
发明人： Stephen Niall Scott , Ashok Krishnapillai
IPC分类号： A23L1/29 , A23C9/142 , A23C9/146
CPC分类号： A23C9/1425 , A23C9/1422 , A23C9/1427 , A23C9/146 , A23C2210/206
摘要： A process for the demineralization and fractionation of cheese whey or raw milk comprising the steps of: a) subjecting the whey or raw milk to ultrafiltration to provide a retentate fraction and a permeate fraction; b) concentrating the permeate fraction by means of nanofiltration; c) subjecting the nanofiltration retentate to ion permeation chromatography at elevated temperatures of between 50° C. and 80° C. using an appropriate resin; and d) eluting the nanofiltration retentate with water in various fractions to obtain fractions which may be low in mineral content and/or high in 3′-sialyl lactose content and/or high in other desirable components.
摘要翻译：一种干酪乳清或生奶的去矿化和分馏的方法，包括以下步骤：a）使乳清或生奶进行超滤以提供滞留物部分和渗透部分; b）通过纳滤法浓缩渗透部分; c）使用合适的树脂在纳米过滤滞留物进行离子渗透色谱之间的温度为50℃至80℃; 和d）用各种级分的水洗脱纳滤滤液，得到矿物质含量低和/或3'-唾液酸乳糖含量高和/或其它所需组分高的级分。

4. 发明授权

US08551547B2 Process for the preparation of angiogenin 有权
标题翻译：血管生成素的制备方法
公开(公告)号：US08551547B2
公开(公告)日：2013-10-08
申请号：US12447889
申请日：2007-11-09
申请人： Andrew Brown , Michelle Rowney , Peter Hobman , Matthew McDonagh , Angus Tester , Benjamin Cocks
发明人： Andrew Brown , Michelle Rowney , Peter Hobman , Matthew McDonagh , Angus Tester , Benjamin Cocks
IPC分类号： C12H1/04 , A23C9/12
CPC分类号： A23C9/146 , A23L33/18 , A23L33/19 , A61K35/20 , A61K38/00 , C07K14/515
摘要： The invention provides a process for the preparation of an angiogenin-enriched fraction from a milk product, the process comprising contacting the milk product with a cation exchange resin and eluting the angiogenin-enriched fraction from the cation exchange resin with a mobile phase. The invention also provides angiogenin-enriched fractions produced by process and food products, nutraceuticals and pharmaceutical comprising such angiogenin.
摘要翻译：本发明提供了一种从乳制品制备富含血管生成素的级分的方法，该方法包括使乳制品与阳离子交换树脂接触，并用流动相从阳离子交换树脂中洗脱含血管生成素的部分。本发明还提供由方法和食品，营养药物和包含这种血管生成素的药物产生的富含血管生成素的级分。

5. 发明申请

US20040197440A1 Milk product and process 失效
标题翻译：奶制品和工艺
公开(公告)号：US20040197440A1
公开(公告)日：2004-10-07
申请号：US10149162
申请日：2004-04-15
发明人： Ganugapati Vijaya Bhaskar , Brian Ashley Kells
IPC分类号： A23C009/12
CPC分类号： A23C9/1422 , A23C9/146 , A23C9/1565 , A23C2240/20
摘要： The invention relates to a translucent milk drink and a method for preparing it. The drink may be prepared by (a) providing an opaque milk starting material having a pH in the range of 5.6-8.0, preferably 5.6-7.0, most preferably 5.7-6.5; (b) contacting at least a portion of the starting material with a cation exchanger until the percentage transmission of the material (when separated from the exchanger) rises to at least 5%, preferably at least 25%, more preferably at least 40%; (c) optionally mixing the translucent milk sample with another milk sample while retaining the percentage transmission at least 5%, preferably at least 25%, more preferably at least 40%. The milk drink may be used as the base for a soft drink like milk drink, which may be carbonated.
摘要翻译：本发明涉及半透明乳饮料及其制备方法。饮料可以通过（a）提供pH为5.6-8.0，优选5.6-7.0，最优选5.7-6.5的不透明乳原料制备; （b）使至少一部分起始材料与阳离子交换剂接触，直到材料的百分比传输（当与交换器分离时）升至至少5％，优选至少25％，更优选至少40％; （c）任选地将半透明乳样品与另一种乳样品混合，同时保持百分比透射率至少5％，优选至少25％，更优选至少40％。牛奶饮料可以用作软饮料的基础，例如可以碳酸化的牛奶饮料。

6. 发明授权

US06472011B1 L-carnitine agent 有权
标题翻译：左旋肉碱剂
公开(公告)号：US06472011B1
公开(公告)日：2002-10-29
申请号：US09923849
申请日：2001-08-07
申请人： Takafumi Yakabe , Kiyoko Ozaki , Masaharu Shimatani , Tadashi Idota
发明人： Takafumi Yakabe , Kiyoko Ozaki , Masaharu Shimatani , Tadashi Idota
IPC分类号： A61K3114
CPC分类号： C07C227/28 , A23C9/1427 , A23C9/144 , A23C9/146 , A23C9/20 , C07C229/22
摘要： An L-carnitine agent has an indispensable function in the body and utility as a material for pharmaceutical agents or food and drink. By subjecting milk or modified milk products of mammals from which casein is removed, to the treatment of desalting and partial removal of lactose followed by drying, L-carnitine content, lactose content, and ash content are adjusted to 0.1˜100 mmol/100 g, 20˜95 g/100 g, and 5 g/100 g or less, respectively.
摘要翻译：左旋肉碱剂在身体和作为药剂或食品和饮料的材料中具有不可或缺的功能。通过将除去酪蛋白的哺乳动物的牛奶或改性乳制品进行脱盐处理和部分除去乳糖，然后干燥，将L-肉碱含量，乳糖含量和灰分调节至0.1〜100mmol / 100g ，20〜95g / 100g，5g / 100g以下。

7. 发明授权

US5310565A Method of removing antibiotics from milk 失效
标题翻译：从牛奶中除去抗生素的方法
公开(公告)号：US5310565A
公开(公告)日：1994-05-10
申请号：US866905
申请日：1992-04-10
申请人： James E. Geyer
发明人： James E. Geyer
IPC分类号： A23C9/146 , A23C7/04
CPC分类号： A23C9/146
摘要： This invention relates to the treatment of milk and milk products and more particularly to a method of removing antibiotics and animal drugs from milk without substantially changing the composition of the milk comprising the steps of: a) heating milk contaminated with an antibiotic to a temperature sufficient to solubilize fats; b) contacting the milk with a resin for a period of time sufficient to allow the resin to extract antibiotics contained in the milk; and c) collecting the milk.
摘要翻译：本发明涉及牛奶和奶制品的处理，更具体地说，涉及从牛奶中除去抗生素和动物药物而不显着改变牛奶组成的方法，包括以下步骤：a）将被抗生素污染的牛奶加热到足够的温度溶解脂肪 b）使乳与树脂接触足以允许树脂提取牛奶中包含的抗生素的时间; 和c）收集牛奶。

8. 发明授权

US4676988A Low-acid juice-milk beverages, juice and milk components therefor and methods of preparation 失效
标题翻译：低酸果汁乳饮料，果汁及其乳成分及其制备方法
公开(公告)号：US4676988A
公开(公告)日：1987-06-30
申请号：US591137
申请日：1984-03-19
申请人： John D. Efstathiou , Robert Dechaine , Robert Zoss
发明人： John D. Efstathiou , Robert Dechaine , Robert Zoss
IPC分类号： A23C9/146 , A23C9/156 , A23L2/02
CPC分类号： A23C9/1565 , A23C9/146 , A23L2/02
摘要： Disclosed are juice-milk beverages exhibiting minimal curdling and/or precipitation; new juice components and milk components for such beverages; and ion exchange methods of preparing such components and beverages. The milk component is prepared by first decationizing milk by contacting with a cation exchanging resin to a pH of below 3.2 to 1.5, and then anion exchanging to a pH of 3.5 to 4.5. The juice component is decationized to a pH of 2.5 to 1.3, deanionized to a pH of 8-11.5, and then acidulated by cation exchange to a pH of 3.0 to 4.5. Blends of the juice and milk are then essentially homogenized and then optionally pasteurized or sterilized and/or carbonated to prepare the new beverages.
摘要翻译：公开了显示出最小的凝结和/或沉淀的果汁 - 牛奶饮料; 这种饮料的新的果汁组分和牛奶组分; 以及制备这些组分和饮料的离子交换方法。通过首先通过与阳离子交换树脂接触至低于3.2至1.5的pH，然后阴离子交换至3.5至4.5的pH来分级乳制备乳组分。将果汁成分分解为2.5〜1.3的pH值，脱色至pH8〜11.5，然后通过阳离子交换酸化至3.0〜4.5的pH。然后将果汁和牛奶的混合物基本均化，然后任选地巴氏消毒或灭菌和/或碳酸化以制备新饮料。

9. 发明授权

US4525366A Process for treating a milk serum product 失效
标题翻译：处理乳清产品的方法
公开(公告)号：US4525366A
公开(公告)日：1985-06-25
申请号：US488446
申请日：1983-04-25
申请人： Rene J. M. Bolzer , Jean Clanchin
发明人： Rene J. M. Bolzer , Jean Clanchin
IPC分类号： A23C9/146 , A23C21/00 , A23J3/08 , A23C9/14
CPC分类号： A23J3/08 , A23C21/00 , A23C9/146
摘要： A milk serum product is delipidated and freed from microorganisms by adjusting the pH of the milk serum product to 4.3-5.0, causing coagulation in the pH adjusted milk serum product by heating it and adding milk casein substance thereto, and then separating coagulated material from the treated milk serum product.
摘要翻译：通过将乳清产品的pH调节至4.3-5.0，将乳清产品脱脂并脱除微生物，通过加热并加入乳酪酪蛋白质将pH调节乳清产物凝结，然后将凝结物从处理过的乳清产品。

10. 发明授权

US4138501A Demineralization of whey 失效
标题翻译：乳清脱矿质
公开(公告)号：US4138501A
公开(公告)日：1979-02-06
申请号：US901524
申请日：1978-05-01
申请人： Michel Chaveron , Jaak-Juri Sihver , Hubert Duperrex
发明人： Michel Chaveron , Jaak-Juri Sihver , Hubert Duperrex
IPC分类号： A23C9/144 , A23C9/146 , A23C9/20 , A23C11/04 , A23C9/14
CPC分类号： A23C11/04 , A23C9/144 , A23C9/146 , A23C9/20
摘要： A process for the treatment of milk serum in order to obtain a demineralized milk serum, which comprises subjecting the milk serum, in a clarified and skimmed state, to electrodialysis, and then to ion exchange with the aid of a strong cation exchange resin in the H.sup.+ cycle and a weak anion exchange resin in the OH.sup.- cycle.
摘要翻译：一种用于处理乳清液以获得软化牛奶血清的方法，其包括将澄清和脱脂状态的乳清血清进行电渗析，然后借助于强阳离子交换树脂进行离子交换 H +循环和OH-循环中的弱阴离子交换树脂。

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