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    • 4. 发明授权
    • Sliding vane pump with internal cam ring
    • 带内部凸轮环的滑动叶片泵
    • US09188005B2
    • 2015-11-17
    • US12389514
    • 2009-02-20
    • Robert R. KimberlinJie Jiang
    • Robert R. KimberlinJie Jiang
    • F01C21/08F04C2/344F04C14/06F04C14/26F04C14/28
    • F01C21/0836F04C2/3446F04C14/06F04C14/26F04C14/28F04C2270/21F04C2270/701F05C2225/00
    • The present disclosure provides a fluid pump having a pump motor, a pump drive shaft and a vane pump assembly. The pump assembly includes a pump housing having fluid inlet and outlet ports. The pump assembly also includes a distal bearing member having first and second sides and a second side, a plurality of inlet orifices, and a cavity formed in the second side. A first cam ring, having an elliptical interior opening, is disposed within the pump housing adjacent the distal bearing member. A rotor is disposed within the opening in the first cam ring. This rotor has first and second sides, a cavity in the first side, and a plurality of radial slots for sliding vanes. The vane pump assembly also includes a second cam ring, having an elliptical shape, disposed in the cavities formed in the distal bearing member second side and the rotor first side. In addition, the vane pump assembly includes a proximate bearing member disposed within the pump housing adjacent the first cam ring and having a plurality of outlet orifices.
    • 本公开提供了一种具有泵马达,泵驱动轴和叶片泵组件的流体泵。 泵组件包括具有流体入口和出口的泵壳体。 泵组件还包括具有第一侧和第二侧以及第二侧的远侧轴承构件,多个入口孔和形成在第二侧中的空腔。 具有椭圆形内部开口的第一凸轮环设置在泵外壳内邻近远侧轴承部件。 转子设置在第一凸轮环的开口内。 该转子具有第一侧和第二侧,第一侧中的空腔和用于滑动叶片的多个径向槽。 叶片泵组件还包括具有椭圆形状的第二凸轮环,其设置在形成在远端轴承部件第二侧和转子第一侧的空腔中。 此外,叶片泵组件包括邻近的第一凸轮环设置在泵壳体内并具有多个出口孔的邻近轴承构件。
    • 5. 发明申请
    • Sliding Vane Pump with Internal Cam Ring
    • 具有内部凸轮环的滑动叶片泵
    • US20090180913A1
    • 2009-07-16
    • US12389514
    • 2009-02-20
    • Robert R. KimberlinJie Jiang
    • Robert R. KimberlinJie Jiang
    • F01C1/00
    • F01C21/0836F04C2/3446F04C14/06F04C14/26F04C14/28F04C2270/21F04C2270/701F05C2225/00
    • The present disclosure provides a fluid pump having a pump motor, a pump drive shaft and a vane pump assembly. The pump assembly includes a pump housing having fluid inlet and outlet ports. The pump assembly also includes a distal bearing member having first and second sides and a second side, a plurality of inlet orifices, and a cavity formed in the second side. A first cam ring, having an elliptical interior opening, is disposed within the pump housing adjacent the distal bearing member. A rotor is disposed within the opening in the first cam ring. This rotor has first and second sides, a cavity in the first side, and a plurality of radial slots for sliding vanes. The vane pump assembly also includes a second cam ring, having an elliptical shape, disposed in the cavities formed in the distal bearing member second side and the rotor first side. In addition, the vane pump assembly includes a proximate bearing member disposed within the pump housing adjacent the first cam ring and having a plurality of outlet orifices.
    • 本公开提供了一种具有泵马达,泵驱动轴和叶片泵组件的流体泵。 泵组件包括具有流体入口和出口的泵壳体。 泵组件还包括具有第一侧和第二侧以及第二侧的远侧轴承构件,多个入口孔和形成在第二侧中的空腔。 具有椭圆形内部开口的第一凸轮环设置在泵外壳内邻近远侧轴承部件。 转子设置在第一凸轮环的开口内。 该转子具有第一侧和第二侧,第一侧中的空腔和用于滑动叶片的多个径向槽。 叶片泵组件还包括具有椭圆形状的第二凸轮环,其设置在形成在远端轴承部件第二侧和转子第一侧的空腔中。 此外,叶片泵组件包括邻近的第一凸轮环设置在泵壳体内并具有多个出口孔的邻近轴承构件。
    • 6. 发明授权
    • Andrographolide derivatives and use thereof in manufacture of medicaments
    • 穿心莲内酯衍生物及其在药物制造中的应用
    • US08367720B2
    • 2013-02-05
    • US12672476
    • 2008-08-07
    • Yuqiang WangXiaojian JiangJie JiangZaijun ZhangZhaoqi YangPei Yu
    • Yuqiang WangXiaojian JiangJie JiangZaijun ZhangZhaoqi YangPei Yu
    • A01N43/08A01N57/00A61K31/34A61K31/665A61K31/585C07D307/02C07D307/00
    • C07D307/58C07D307/60C07D409/12
    • The present invention relates to an andrographolide derivative of the formula (I), wherein R1, R2 and R3 are same or different substituents selected from hydrogen, substituted or unsubstituted organic acid radicals, inorganic acid radicals, alkyl, aryl or heteroaryl, and at least one of R1, R2 and R3 is R-lipoic acid, S-lipoic acid or a mixture thereof, or corresponding dihydrolipoic acids thereof, or N-acetylcysteine radical. The derivative has good antitumor effect, can induce apoptosis of tumor cells, can directly kill Gram-positive bacteria (staphylococcus aureus) and drug resistance bacteria (MRSA5676 and MRSA5677), can inhibit the QS-system of Gram-negative bacteria (Pseudomonas aeruginosa), can inhibit and destroy the formation of biofilm of Pseudomonas aeruginosa; and exhibits significant hypoglycemic effect, so that it can be used in manufacture of medicaments for treatment of cancers, inflammation, diabetes, and bacterial and viral infections.
    • 本发明涉及式(I)的穿心莲内酯衍生物,其中R 1,R 2和R 3是相同或不同的选自氢,取代或未取代的有机酸基,无机酸基,烷基,芳基或杂芳基的取代基,至少 R1,R2和R3之一是R-硫辛酸,S-硫辛酸或其混合物,或其相应的二氢硫辛酸或N-乙酰半胱氨酸碱基。 该衍生物具有良好的抗肿瘤作用,可诱导肿瘤细胞凋亡,可直接杀死革兰氏阳性菌(金黄色葡萄球菌)和耐药细菌(MRSA5676和MRSA5677),可抑制革兰氏阴性菌(绿脓假单胞菌)的QS系统, ,可以抑制和破坏铜绿假单胞菌生物膜的形成; 并显示出显着的降血糖作用,因此可用于制造用于治疗癌症,炎症,糖尿病以及细菌和病毒感染的药物。