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1. 发明申请

US20110034485A1 NITRONE COMPOUNDS, PROCESS OF PREPARATION THEREOF, AND USE THEREOF IN MEDICAMENT MANUFACTURE 有权
标题翻译：硝基化合物，其制备方法及其在药物制造中的应用
公开(公告)号：US20110034485A1
公开(公告)日：2011-02-10
申请号：US12937405
申请日：2009-04-16
申请人： Yuqiang Wang , Jie Jiang , Pei Yu , Yewei Sun , Linda Wang , Zaijun Zhang
发明人： Yuqiang Wang , Jie Jiang , Pei Yu , Yewei Sun , Linda Wang , Zaijun Zhang
IPC分类号： A61K31/505 , C07D239/30 , A61P25/00 , A61P9/00 , A61P27/02 , A61P29/00 , A61P35/00
CPC分类号： C07D241/12
摘要： The present invention provides novel nitrones, their preparation and use. The novel compounds have the following formula: I The compounds of the present invention have strong antioxidative activity, and are thrombolytic. These compounds can be used to treat and/or prevent diseases caused by overproduction of free radicals and/or formation of thrombus.
摘要翻译：本发明提供新的硝酮，其制备和用途。该化合物具有以下结构式：I本发明化合物具有较强的抗氧化活性，且具有血栓溶解作用。这些化合物可用于治疗和/或预防由过度产生自由基和/或形成血栓引起的疾病。

2. 发明授权

US07141172B2 Versatile simulated moving bed systems 失效
标题翻译：多功能模拟移动床系统
公开(公告)号：US07141172B2
公开(公告)日：2006-11-28
申请号：US10416826
申请日：2002-09-27
申请人： Nien-Hwa Linda Wang , Chim Yong Chin
发明人： Nien-Hwa Linda Wang , Chim Yong Chin
IPC分类号： B01D15/08
CPC分类号： B01D53/0446 , B01D15/1842 , B01D53/0454 , B01D53/08 , B01D2215/023 , B01D2257/90 , B01D2259/40005 , B01D2259/40086 , B01D2259/4067
摘要： Distributed valve simulated moving beds are described in which junctions located between successive columns interrupt the flow of process fluid between columns, and either transmit the process fluid through a zone bypass to a succeeding column within the same zone or, if the junction is located between zones, direct the process fluid to an input/output line that is dedicated to the particular zone that immediately follows the junction. At each step of the SMB's operation, the distribution of flows in each junction is modulated to accomplish movement of ports consistent with the SMB's design. Further described are simulated moving beds that contain one or more decoupled on-line regeneration zones. The regeneration zone is decoupled from the separation zones in the sense that it observes a step time (a “regeneration interval”) that is different than the step time observed by the separation zones of the SMB. Because the regeneration zone is “on-line,” the SMB need not be stopped to remove columns for regeneration. Because the regeneration zone is decoupled from the separation zones, the column can stay in the regeneration zone as long as needed to accomplish the regeneration, regardless of the step time observed by the SMB.
摘要翻译：描述了分布式阀模拟移动床，其中位于连续柱之间的连接点中断了塔之间的过程流体的流动，并且将过程流体通过区域旁路传送到同一区域内的后续柱，或者如果结点位于区域之间将工艺流体引导到专用于紧接在结点之后的特定区域的输入/输出线。在SMB运营的每个步骤中，调整每个交叉点的流量分布，以实现与SMB设计一致的端口的移动。进一步描述的是包含一个或多个解耦的在线再生区的模拟移动床。在再现区域与分离区域分离的意义上，它观察到与SMB分离区观察到的步进时间不同的步骤时间（“再生间隔”）。因为再生区域是“在线”，所以不需要停止SMB以除去再生区。因为再生区域与分离区分离，所以只要需要完成再生，柱子就可以停留在再生区域中，而不管SMB观察到的步骤时间如何。

3. 发明授权

US08404688B2 Nitrone compounds, process of preparation thereof, and use thereof in medicament manufacture 有权
标题翻译：硝基化合物，其制备方法及其在药物制备中的应用
公开(公告)号：US08404688B2
公开(公告)日：2013-03-26
申请号：US12937405
申请日：2009-04-16
申请人： Yuqiang Wang , Jie Jiang , Pei Yu , Yewei Sun , Linda Wang , Zaijun Zhang
发明人： Yuqiang Wang , Jie Jiang , Pei Yu , Yewei Sun , Linda Wang , Zaijun Zhang
IPC分类号： A61K31/4965
CPC分类号： C07D241/12
摘要： The present invention provides novel nitrones, their preparation and use. The novel compounds have the following formula: I The compounds of the present invention have strong antioxidative activity, and are thrombolytic. These compounds can be used to treat and/or prevent diseases caused by overproduction of free radicals and/or formation of thrombus.
摘要翻译：本发明提供新的硝酮，其制备和用途。该化合物具有以下结构式：I本发明化合物具有较强的抗氧化活性，且具有血栓溶解作用。这些化合物可用于治疗和/或预防由过度产生自由基和/或形成血栓引起的疾病。

4. 发明授权

US06843854B2 Method and apparatus for separating a component from a mixture 失效
标题翻译：用于从混合物中分离组分的方法和装置
公开(公告)号：US06843854B2
公开(公告)日：2005-01-18
申请号：US10159313
申请日：2002-05-31
申请人： Chad Farrenburg , Nien-Hwa Linda Wang , Yi Xie , Benjamin J. Hritzk
发明人： Chad Farrenburg , Nien-Hwa Linda Wang , Yi Xie , Benjamin J. Hritzk
IPC分类号： B01D15/18 , C07H1/06 , C07H17/08 , A23N1/00
CPC分类号： C07H17/08 , B01D15/1842 , B01D15/185 , B01D15/327 , C07H1/06
摘要： The present invention comprises the optimization of a four zone simulated moving bed system configured to separate a first component from a mixture containing the first component and a second component wherein the first component exhibits non-linear adsorption and non-negligible mass transfer resistances. In one example, the four zone simulated moving bed is optimized to separate Clarithromycin from a mixture containing Clarithromycin and 6,11-O-methyl erythromycin A. The present invention further comprises a four zone or a five zone apparatus having a first portion and a second portion and the optimization of the four zone or five zone apparatus to separate a first component from a mixture containing the first component and a second component and the method of using the same. In one example, the four zone and five zone simulated moving beds are optimized to separate Clarithromycin from a mixture containing Clarithromycin and 6,11-O-methyl erythromycin A. The present invention further comprises a batch elution system configured to separate Clarithromycin from a mixture containing Clarithromycin and 6,11-O-methyl erythromycin A.
摘要翻译：本发明包括四区模拟移动床系统的优化，该四区模拟移动床系统被配置为从包含第一组分和第二组分的混合物中分离第一组分，其中第一组分表现出非线性吸附和不可忽略的质量传递电阻。在一个实例中，四区模拟移动床被优化以将克拉霉素与含有克拉霉素和6,11-O-甲基红霉素A的混合物分离。本发明还包括四区或五区设备，其具有第一部分和第二部分和四区或五区设备的优化，以将第一组分与含有第一组分和第二组分的混合物分离出来，以及使用该组分的方法。在一个实例中，四区和五区模拟移动床被优化以将克拉霉素与含有克拉霉素和6,11-O-甲基红霉素A的混合物分离。本发明还包括配置为将克拉霉素与混合物分离的间歇洗脱系统含有克拉霉素和6,11-O-甲基红霉素A.

5. 发明授权

US5956865A Process for drying herbs 失效
标题翻译：草药干燥过程
公开(公告)号：US5956865A
公开(公告)日：1999-09-28
申请号：US81212
申请日：1998-05-20
申请人： Timothy Douglas Durance , Dragan Macura , Richard Scholmer Meyer , Alex N. Yousif , Christine H. Scaman , Jianhua (Linda) Wang
发明人： Timothy Douglas Durance , Dragan Macura , Richard Scholmer Meyer , Alex N. Yousif , Christine H. Scaman , Jianhua (Linda) Wang
IPC分类号： F26B5/04 , F26B3/34
CPC分类号： F26B5/048
摘要： Herbs are dried by applying microwave power to herbs in a chamber under reduced or negative pressure to reduce the moisture content of the herbs without significantly damaging the flavor of the dried herbs and produce a dried herb having a flavor more closely approaching the flavor of fresh herbs than dried herbs produced by conventional processes.
摘要翻译：通过在减压或负压下在室内对草药施加微波功率使草药干燥，以减少草药的水分含量，而不会显着损害干草药的风味，并产生具有更接近新鲜草药风味的风味的干草本植物比通过常规方法生产的干草药。

6. 发明申请

US20230093246A1 MULTI-DIMENSIONAL LIGAND-ASSISTED CHROMATOGRAPHY METHOD FOR THE PURIFICATION OF RARE EARTH ELEMENTS AND OTHER METAL IONS FROM WASTE MAGNETS 有权
公开(公告)号：US20230093246A1
公开(公告)日：2023-03-23
申请号：US17797826
申请日：2021-01-28
申请人： Nien-Hwa Linda WANG , David HARVEY , Yi DING , Purdue Research Foundation
发明人： Nien-Hwa Linda Wang , David Harvey , Yi Ding
IPC分类号： C22B59/00 , B01D15/38 , B01D15/20 , B01D15/18 , C22B3/42 , C22B3/06
摘要： A method of recovering substantially rare earth elements (REEs) from magnets, including first dissolving a magnet to yield a solution containing Nd, Pr, and Dy, and then equilibrating a first column with Cu2+ solution to yield a first equilibrated column, introducing the solution to the first equilibrated column, and introducing a ligand solution to the first equilibrated column to establish three bands of different liquid compositions in the column, wherein the three bands comprise a Dy/Nd mixed band, a first pure Nd band, and a Nd/Pr mixed band. Next, sending the Dy/Nd mixed band to a second column containing a Cu2+ solution and introducing a ligand solution to the second column to establish a pure Dy band and a second pure Nd band in the second column, and sending the Nd/Pr mixed band to a third column containing a Cu2+ solution and introducing a ligand solution to the third column to establish a third pure Nd band and a pure Pr band in the third column. Finally, eluting the respective pure Nd bands to recover Nd, eluting the pure Dy band to recover Dy, and eluting the pure Pr band to recover Pr.

7. 发明申请

US20220195559A1 PREPARATION OF RARE EARTH METALS AND OTHER CHEMICALS FROM INDUSTRIAL WASTE COAL ASH 有权
公开(公告)号：US20220195559A1
公开(公告)日：2022-06-23
申请号：US17536403
申请日：2021-11-29
申请人： Nien-Hwa Linda Wang , Hoon Choi , David Harvey
发明人： Nien-Hwa Linda Wang , Hoon Choi , David Harvey
IPC分类号： C22B7/00 , C22B7/02 , C22B3/42 , C22B3/44 , C01B33/14 , C22B59/00 , C22B21/00 , C22B3/10 , C01G49/06 , C01F7/0693 , C01F11/02 , C01G49/02 , C01F11/24 , C01B33/26 , C01B33/32 , C01G49/10 , C01F17/271 , C22B3/06 , C22B3/08
摘要： A process disclosed herein is related to the isolation and purification of substantially pure chemicals, including silica gel, sodium silicate, aluminum silicate, iron oxide, and rare earth elements (or rare earth metals, REEs), from massive industrial waste coal ash. In one embodiment, the process includes a plurality of caustic extractions of coal ash at an elevated temperature, followed by an acidic treatment to dissolve aluminum silicate and REEs. The dissolved aluminum silicate is precipitated out by pH adjustment as a solid product while REEs remain in the solution. REEs are captured and enriched using an ion exchange column. Alternatively, the solution containing aluminum silicate and REEs is heated to produce silica gel, which is easily separated from the enriched REEs solution. REEs are then isolated and purified from the enriched solution to afford substantially pure individual REE by a ligand-assisted chromatography. Additionally, a simplified process using one caustic extraction and one acidic extraction with an ion exchange process was also investigated and optimized to afford a comparable efficiency.

8. 发明申请

US20120325691A1 KIND OF PACKING BOX OF WET WIPES 有权
标题翻译：包装盒的WIP WIPES的种类
公开(公告)号：US20120325691A1
公开(公告)日：2012-12-27
申请号：US13595310
申请日：2012-08-27
申请人： Linda WANG
发明人： Linda WANG
IPC分类号： B65D43/22
CPC分类号： A47K10/421 , A47K2010/3266
摘要： A packing box of wet wipes, which includes a body and a cover connected to the body. The cover includes: a cover body having a press button mounted therein, a top lid having a fastening part mounted thereon and mated with the press button, and a resilient connection part having a first end secured to a side of the top lid opposite to the fastening part and a second end protruding through a through hole of the top lid and secured to the cover body. The packing box of wet wipes of present invention has a simple structure, and can be used repeatedly and easy to open.
摘要翻译：一种湿巾包装盒，其包括主体和连接到身体的盖子。所述盖包括：具有安装在其中的按钮的盖体，具有安装在其上并与所述按钮配合的紧固部的顶盖，以及弹性连接部，所述弹性连接部具有固定到所述顶盖的与所述第一端相对的一侧的第一端紧固部分和通过顶盖的通孔突出并固定到盖体的第二端。本发明的湿巾包装盒具有简单的结构，可重复使用并易于打开。

9. 发明授权

US08499958B2 Kind of packing box of wet wipes 有权
标题翻译：湿巾包装盒种类
公开(公告)号：US08499958B2
公开(公告)日：2013-08-06
申请号：US13595310
申请日：2012-08-27
申请人： Linda Wang
发明人： Linda Wang
IPC分类号： B65D43/22
CPC分类号： A47K10/421 , A47K2010/3266
摘要： A packing box of wet wipes, which includes a body and a cover connected to the body. The cover includes: a cover body having a press button mounted therein, a top lid having a fastening part mounted thereon and mated with the press button, and a resilient connection part having a first end secured to a side of the top lid opposite to the fastening part and a second end protruding through a through hole of the top lid and secured to the cover body. The packing box of wet wipes of present invention has a simple structure, and can be used repeatedly and easy to open.
摘要翻译：一种湿巾包装盒，其包括主体和连接到身体的盖子。所述盖包括：具有安装在其中的按钮的盖体，具有安装在其上并与所述按钮配合的紧固部的顶盖，以及弹性连接部，所述弹性连接部具有固定到所述顶盖的与所述第一端相对的一侧的第一端紧固部分和通过顶盖的通孔突出并固定到盖体的第二端。本发明的湿巾包装盒具有简单的结构，可重复使用并易于打开。

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