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    • 6. 发明授权
    • Process for the production of acid anhydrides from epoxides
    • 从环氧化物生产酸酐的方法
    • US09403788B2
    • 2016-08-02
    • US14378290
    • 2013-02-12
    • Novomer, Inc.
    • Han LeeMichael A. Slowik
    • C07D307/60C07D303/12B01J31/22C07D305/12
    • C07D307/60B01J31/2295B01J2231/48B01J2531/31B01J2531/845C07D303/12C07D305/12
    • A method of making acid anhydrides from epoxide and carbon monoxide feedstocks is presented. In various aspects, the method includes steps of reacting the contents of a feed stream comprising an epoxide, a solvent, a carbonylation catalyst and carbon monoxide to produce a first carbonylation product stream comprising a beta-lactone, then reacting the contents of the first carbonylation product stream with additional carbon monoxide to produce a second carbonylation product stream comprising an acid anhydride, and separating at least a portion of the acid anhydride from the second carbonylation product stream to produce: i) an acid anhydride product stream comprising the separated portion of acid anhydride; and ii) a recycling stream comprising the carbonylation catalyst, and finally adding the recycling stream to the feed stream.
    • 提出了一种从环氧化物和一氧化碳原料制备酸酐的方法。 在各个方面,该方法包括使包含环氧化物,溶剂,羰基化催化剂和一氧化碳的进料流的内容物反应以产生包含β-内酯的第一羰基化产物流,然后使第一羰基化反应的内容物 产生含有一氧化碳的产物流以产生包含酸酐的第二羰基化产物流,并将至少一部分酸酐与第二羰基化产物流分离以产生:i)包含酸的分离部分的酸酐产物流 酐; 和ii)包含羰基化催化剂的再循环流,最后将再循环流加入进料流中。
    • 9. 发明申请
    • METHOD OF MANUFACTURING PYRIDAZINONE COMPOUND
    • 制备吡咯烷酮化合物的方法
    • US20160060225A1
    • 2016-03-03
    • US14779383
    • 2014-03-17
    • SUMITOMO CHEMICAL COMPANY, LIMITED
    • Akio MANABE
    • C07D237/14C07D307/60
    • C07D237/14C07D237/16C07D307/60
    • A compound represented by formula (2) wherein X represents a hydrogen atom, a fluorine atom, a chlorine atom or a bromine atom, and Y represents a hydrogen atom, a fluorine atom, a chlorine atom or a bromine atom,is reacted with a brominating agent and an alkanol having 1 to 6 carbon atoms in the presence of a base to obtain a compound represented by formula (3) wherein R represents a C1 to C6 alkyl group, and X and Y represent the same meaning as described above,and then the compound represented by the formula (3) is reacted with hydrazine, whereby a compound represented by formula (1) wherein X and Y represent the same meaning as described above, which is useful as a production intermediate of a fungicide, can be obtained.
    • 由式(2)表示的化合物,其中X表示氢原子,氟原子,氯原子或溴原子,Y表示氢原子,氟原子,氯原子或溴原子,与 溴化剂和具有1至6个碳原子的链烷醇,以获得由式(3)表示的化合物,其中R表示C1至C6烷基,X和Y表示与上述相同的含义, 然后将由式(3)表示的化合物与肼反应,由此得到其中X和Y表示与上述相同含义的式(1)表示的化合物,其可用作杀真菌剂的生产中间体 。