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1. 发明申请

US20100057174A1 ELECTRICALLY CONDUCTIVE PATHWAYS IN MEDICAL DEVICES 有权
标题翻译：医疗器械中的电导通道
公开(公告)号：US20100057174A1
公开(公告)日：2010-03-04
申请号：US12199563
申请日：2008-08-27
申请人： Kent D. Harrison , Derek C. Sutermeister , Tim Ostroot
发明人： Kent D. Harrison , Derek C. Sutermeister , Tim Ostroot
IPC分类号： A61N1/04
CPC分类号： A61M25/0009 , A61L29/04 , A61L29/14 , A61M25/0029 , A61M25/0045 , A61M25/0051 , A61M2025/0039 , A61N1/05 , B29C47/0016 , B29C47/06 , B29K2065/00 , B29K2081/04 , B29K2995/0005 , B29L2031/7542 , Y10T29/49117
摘要： Apparatuses, systems, and methods for electrically conductive pathways in medical devices. One embodiment of a medical device can include an elongate polymeric body having a proximal end and a distal end. Discrete particles of an electrically conductive material in the elongate polymeric body can form an electrically conductive pathway that extends at least partially between the proximal end and the distal end of the elongate polymeric body.
摘要翻译：用于医疗器械中导电通路的装置，系统和方法。医疗装置的一个实施例可以包括具有近端和远端的细长聚合体。细长聚合物体中的导电材料的分散颗粒可以形成至少部分地延伸到细长聚合物体的近端和远端之间的导电通路。

2. 发明授权

US08359105B2 Electrically conductive pathways in medical devices 有权
标题翻译：医疗器械中的导电通路
公开(公告)号：US08359105B2
公开(公告)日：2013-01-22
申请号：US12199563
申请日：2008-08-27
申请人： Kent D. Harrison , Derek C. Sutermeister , Tim Ostroot
发明人： Kent D. Harrison , Derek C. Sutermeister , Tim Ostroot
IPC分类号： A61N1/00 , A61M5/00
CPC分类号： A61M25/0009 , A61L29/04 , A61L29/14 , A61M25/0029 , A61M25/0045 , A61M25/0051 , A61M2025/0039 , A61N1/05 , B29C47/0016 , B29C47/06 , B29K2065/00 , B29K2081/04 , B29K2995/0005 , B29L2031/7542 , Y10T29/49117
摘要： Apparatuses, systems, and methods for electrically conductive pathways in medical devices. One embodiment of a medical device can include an elongate polymeric body having a proximal end and a distal end. Discrete particles of an electrically conductive material in the elongate polymeric body can form an electrically conductive pathway that extends at least partially between the proximal end and the distal end of the elongate polymeric body.
摘要翻译：用于医疗器械中导电通路的装置，系统和方法。医疗装置的一个实施例可以包括具有近端和远端的细长聚合体。细长聚合物体中的导电材料的分散颗粒可以形成至少部分地延伸到细长聚合物体的近端和远端之间的导电通路。

3. 发明授权

US07837619B2 Transeptal apparatus, system, and method 有权
标题翻译：过境设备，系统和方法
公开(公告)号：US07837619B2
公开(公告)日：2010-11-23
申请号：US11207317
申请日：2005-08-19
申请人： David J. Sogard , Leonard B. Richardson , Kent D. Harrison , Diane M. Sheahen
发明人： David J. Sogard , Leonard B. Richardson , Kent D. Harrison , Diane M. Sheahen
IPC分类号： A61B1/00 , A61B17/08
CPC分类号： A61B17/0057 , A61B17/3478 , A61B2017/00243 , A61B2017/00575 , A61B2017/3488
摘要： Methods, apparatus, and systems for locating a patent foramen ovale (PFO) with a positioning device that can be configured to occlude the PFO. Methods, apparatus, and systems include the use of a positioning device that can be seated on the limbus of a septum secundum (SS). The positioning device includes a piercing member that can pierce the SS and a septum primum.
摘要翻译：用于定位具有定位装置的专利孔卵孔（PFO）的方法，装置和系统，所述定位装置可被配置为闭塞PFO。方法，装置和系统包括使用可以坐在隔膜（SS）的角膜缘上的定位装置。该定位装置包括能刺穿SS和穿孔的刺穿构件。

4. 发明授权

US06575168B2 System and method for percutaneous coronary artery bypass 有权
标题翻译：经皮冠状动脉旁路的系统和方法
公开(公告)号：US06575168B2
公开(公告)日：2003-06-10
申请号：US09759996
申请日：2001-01-12
申请人： Daniel M. LaFontaine , Kent D. Harrison , Charles L. Euteneuer , Roger N. Hastings , Lixiao Wang
发明人： Daniel M. LaFontaine , Kent D. Harrison , Charles L. Euteneuer , Roger N. Hastings , Lixiao Wang
IPC分类号： A61B1900
CPC分类号： A61F2/82 , A61B17/32053 , A61B2017/00243 , A61B2017/00252 , A61B2017/1135 , A61B2017/306 , A61B2090/3929 , A61B2090/3945 , A61B2090/3958 , A61F2/06 , A61F2/064 , A61F2/90 , A61F2/958 , A61F2250/0098 , Y10S623/902
摘要： A percutaneous system for bypassing a restriction in a native vessel of a mammal having an aorta includes providing a graft having a body portion with a first end, a second end and a lumen therebetween. An aperture is formed in the aorta. The graft is inserted into the aorta and the first end of the graft is connected to the aorta about the aperture in the aorta. An aperture is then formed in the native vessel distal of the restriction. The second end of the graft is connected to the native vessel about the aperture therein such that the lumen in the graft communicates with the aorta and the native vessel.
摘要翻译：用于绕过具有主动脉的哺乳动物的天然血管中的限制的经皮系统包括提供具有主体部分的移植物，其具有第一端，第二端和其间的内腔。在主动脉中形成孔。将移植物插入主动脉，并且移植物的第一端围绕主动脉的孔连接到主动脉。然后在限制器的远端的天然血管中形成孔。移植物的第二端围绕其中的孔连接到天然血管，使得移植物中的内腔与主动脉和天然血管连通。

5. 发明授权

US06299628B1 Method and apparatus for catheter exchange 失效
标题翻译：用于导管交换的方法和装置
公开(公告)号：US06299628B1
公开(公告)日：2001-10-09
申请号：US07931695
申请日：1992-08-18
申请人： Kent D. Harrison , Scott P. Thome , Peter T. Keith , Daniel O. Adams , William H. Penny
发明人： Kent D. Harrison , Scott P. Thome , Peter T. Keith , Daniel O. Adams , William H. Penny
IPC分类号： A61M2510
CPC分类号： A61M25/0105 , A61M25/0169 , A61M2025/0098
摘要： An apparatus and method for exchanging a first intravascular catheter of the over-the-wire type, such as an angioplasty balloon dilation catheter, with a second intravascular catheter of the over-the-wire type while leaving a guide wire in position in a desired vascular site. The apparatus is used in conjunction with a conventional guide catheter, a guide wire, and an interventional catheter that can be positioned intravascularly through a lumen of the guide catheter over the guide wire and past a distal end of the guide catheter to a desired vascular site. The apparatus includes an elongate shaft that can be removably positioned in the lumen of the guide catheter and has an actuation capability therein. A trapping member is located at a distal portion of the elongate shaft for releasably fixing the relative position of the guide wire with respect to the guide catheter. The fixing and releasing of the trapping member is effected by the actuation capability from outside the body of the patient so that a first interventional catheter can be exchanged for a second interventional catheter by trapping the guide wire position relative to the guide catheter while withdrawing the first interventional device and replacing it with another.
摘要翻译：一种用于与线上类型的第二血管内导管（例如血管成形术球囊扩张导管）交换诸如血管成形术球囊扩张导管的第一血管内导管的装置和方法，同时将引导线留在期望的位置血管部位。该装置与传统的导向导管，导丝和介入导管一起使用，其可以通过引导导管的导管血管内定位并且经过引导导管的远端定位到期望的血管部位。该装置包括细长轴，其可移除地定位在引导导管的内腔中并且在其中具有致动能力。捕获构件位于细长轴的远侧部分，用于可释放地固定导丝相对于导向导管的相对位置。捕获构件的固定和释放通过来自患者体外的致动能力来实现，使得可以通过相对于引导导管捕获引导线位置而将第一介入导管更换为第二介入导管，同时撤回第一介入导管介入装置，并用另一种装置代替。

6. 发明授权

US06443158B1 Percutaneous coronary artery bypass through a venous vessel 失效
标题翻译：经皮冠状动脉旁路穿过静脉血管
公开(公告)号：US06443158B1
公开(公告)日：2002-09-03
申请号：US09088496
申请日：1998-06-01
申请人： Daniel M. LaFontaine , Kent D. Harrison , Chad J. Kugler , John M. K. Daniel
发明人： Daniel M. LaFontaine , Kent D. Harrison , Chad J. Kugler , John M. K. Daniel
IPC分类号： A61B1900
CPC分类号： A61B17/11 , A61B18/1492 , A61B2017/00243 , A61B2017/00252 , A61B2017/1107 , A61B2017/1135 , A61B2017/1139 , A61B2017/22067 , A61B2018/00023 , A61B2018/00261 , A61B2018/00386
摘要： A bypass system for bypassing a restriction in a parent vessel of a mammal to provide blood flow past the restriction. The bypass system couples a restricted artery to a venous vessel distal of a restriction to provide blood flow through the artery distal of the restriction. Blood flow is provided to a distal portion of the artery through an adjacent venous vessel so that blood can be provided to distal portions of the restricted artery.
摘要翻译：用于绕过哺乳动物的母体血管中的限制以提供血液流过限制的旁路系统。旁路系统将限制性动脉连接到限制器远端的静脉血管，以提供通过限制远端的动脉的血液流动。通过相邻的静脉血管将动脉血流提供到动脉的远端部分，以便可以将血液提供到受限动脉的远端部分。

7. 发明授权

US06238406B1 Percutaneous myocardial revascularization growth factor mediums and method 有权
标题翻译：经皮心肌血运重建生长因子介质及方法
公开(公告)号：US06238406B1
公开(公告)日：2001-05-29
申请号：US09516531
申请日：2000-03-01
申请人： Louis Ellis , Gary L. Hendrickson , Kent D. Harrison , Lixiao Wang , Timothy J. Mickley
发明人： Louis Ellis , Gary L. Hendrickson , Kent D. Harrison , Lixiao Wang , Timothy J. Mickley
IPC分类号： A61B1732
CPC分类号： A61B17/32002 , A61B17/320758 , A61B17/3468 , A61B17/3478 , A61B90/39 , A61B2017/00247 , A61B2017/003 , A61B2017/22077 , A61B2017/320084 , A61B2018/00208 , A61B2018/00392 , A61B2018/1425 , A61B2018/1861 , A61F2/2493 , A61M2025/0089
摘要： Devices and methods for increasing blood perfusion within the myocardium of the heart by wounding the myocardium and applying growth factors to promote vascularization. One method includes driving spikes into the myocardium from within the heart, with the spikes being formed of biodegradable material, containing releasable growth factors, and having lumens and side holes. An alternative method utilizes non-biodegradable spikes with lumens and side holes. Another method promotes vascularization by injecting angiogenic material into holes bored into the myocardium, leaving a patent hole. Another method includes injecting angiogenic material into the myocardium without boring, leaving no patent hole. The angiogenic material can be carried in a biodegradable adhesive. Revascularization of the myocardium is promoted in one method by externally wounding the heart and applying a patch including growth factors.
摘要翻译：通过伤害心肌并应用生长因子促进血管形成来增加心脏心肌内的血液灌注的装置和方法。一种方法包括从心脏内将尖峰驱动到心肌中，其中尖峰由可生物降解的材料形成，包含可释放的生长因子，并具有流明和侧孔。一种替代方法是利用不可生物降解的钉与流明和侧孔。另一种方法通过将血管生成材料注入穿入心肌的孔中来促进血管形成，留下专利孔。另一种方法包括将血管生成物质注入到心肌中而无需镗孔，没有留下专利孔。血管生成物质可以携带在可生物降解的粘合剂中。通过外部伤心并施用包括生长因子的贴片在一种方法中促进心肌的血运重建。

8. 发明授权

US06026814A System and method for percutaneous coronary artery bypass 失效
公开(公告)号：US06026814A
公开(公告)日：2000-02-22
申请号：US813038
申请日：1997-03-06
申请人： Daniel M. LaFontaine , Kent D. Harrison , Charles L. Euteneuer , Roger N. Hastings , Lixiao Wang
发明人： Daniel M. LaFontaine , Kent D. Harrison , Charles L. Euteneuer , Roger N. Hastings , Lixiao Wang
IPC分类号： A61B17/00 , A61B17/11 , A61B17/30 , A61B17/32 , A61B19/00 , A61F2/00 , A61F2/06 , A61F2/82 , A61F2/90
CPC分类号： A61F2/82 , A61F2/06 , A61F2/064 , A61B17/32053 , A61B2017/00243 , A61B2017/00252 , A61B2017/1135 , A61B2017/306 , A61B2090/3929 , A61B2090/3945 , A61B2090/3958 , A61F2/90 , A61F2/958 , A61F2250/0098 , Y10S623/902
摘要： A percutaneous system for bypassing a restriction in a native vessel of a mammal having an aorta includes providing a graft having a body portion with a first end, a second end and a lumen therebetween. An aperture is formed in the aorta. The graft is inserted into the aorta and the first end of the graft is connected to the aorta about the aperture in the aorta. An aperture is then formed in the native vessel distal of the restriction. The second end of the graft is connected to the native vessel about the aperture therein such that the lumen in the graft communicates with the aorta and the native vessel.

9. 发明授权

US5964782A Closure device and method 失效
标题翻译：封闭装置和方法
公开(公告)号：US5964782A
公开(公告)日：1999-10-12
申请号：US932990
申请日：1997-09-18
申请人： Daniel M. Lafontaine , Kent D. Harrison
发明人： Daniel M. Lafontaine , Kent D. Harrison
IPC分类号： A61B17/04 , A61B17/00 , A61B17/10 , A61B18/04 , A61B18/14
CPC分类号： A61B18/148 , A61B17/0057 , A61B2017/00637 , A61B2017/00663 , A61B2017/00668 , A61B2017/00672 , A61B2018/00196 , A61B2018/0022 , A61B2018/00273 , A61B2018/00279
摘要： An apparatus is provided for closing a perforation in a wall of a patient's blood vessel or other organs, and a method of introducing the apparatus and causing the closure are described. The apparatus includes an elongated support member having a distal end supporting one or more tissue engaging hooks configured to engage fibrous vessel tissue when moved in a first direction and to disengage the tissue when moved in a second direction, and a proximal end for applying rotational torque to the support member to cause the hooks to engage collagen fibrous tissue in the adventitia of the blood vessel or fibrous tissue in other body organs. The hooks engaging the collagen fiber causes the blood vessel tissue surrounding the perforation to be drawn into close proximity such that the perforation can be closed. The apparatus can be removed by applying reverse rotation of the support member, whereby the hooks are disengaged. The apparatus is deployed in an outer sheath with the hooks encased until a selected engaging location has been achieved. When positioned in the aperture to be closed, the hooks are exposed to allow interaction with the adventitia. Puncture closure can be accomplished by various techniques, including stasis, cauterizing, or by clamping. Various embodiments of the apparatus are described.
摘要翻译：提供了用于封闭患者血管或其他器官的壁中的穿孔的装置，并且描述了引入该装置并引起闭合件的方法。该装置包括细长的支撑构件，其具有支撑一个或多个组织接合钩的远端，所述组织接合钩构造成当沿第一方向移动时接合纤维血管组织，并且在沿第二方向移动时使组织脱离，以及用于施加旋转扭矩的近端到支撑构件以引起钩将胶原纤维组织接合在血管的外膜或其他身体器官中的纤维组织中。接合胶原纤维的钩使得穿孔周围的血管组织被拉近，使得穿孔可以闭合。可以通过施加支撑构件的反向旋转来移除该装置，由此钩脱开。该装置部署在外护套中，钩被包住，直到达到选定的接合位置。当定位在要关闭的孔中时，钩暴露以允许与外膜相互作用。穿刺闭合可以通过各种技术来实现，包括瘀斑，烧灼或夹紧。描述该装置的各种实施例。

10. 发明授权

US5716340A Blood perfusion catheter 失效
标题翻译：血液灌注导管
公开(公告)号：US5716340A
公开(公告)日：1998-02-10
申请号：US715126
申请日：1996-09-17
申请人： Cyril J. Schweich, Jr. , Kent D. Harrison , Matthew M. Burns
发明人： Cyril J. Schweich, Jr. , Kent D. Harrison , Matthew M. Burns
IPC分类号： A61M25/00 , A61F2/958 , A61M16/04 , A61M29/02 , A61M29/00
CPC分类号： A61M25/1002 , A61M16/0481 , A61M2025/105 , A61M2025/1052 , A61M2025/1072 , A61M2025/1097
摘要： A blood perfusion balloon catheter is provided. The perfusion catheter includes an elongate tubular shaft having a proximal portion and a distal portion and a plurality of toroidal-shaped inflatable balloons laced through the distal portion of the tubular shaft, the balloons creating a blood flow lumen when they are inflated. The perfusion catheter may also include a cylindrical sheath attached to the balloons.
摘要翻译：提供血液灌注球囊导管。灌注导管包括细长的管状轴，其具有穿过管状轴的远端部分的近端部分和远端部分以及多个环形形状的可充气气球，所述气囊在充气时产生血流腔。灌注导管还可以包括附接到气囊的圆柱形护套。

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