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1. 发明授权

US06299628B1 Method and apparatus for catheter exchange 失效
标题翻译：用于导管交换的方法和装置
公开(公告)号：US06299628B1
公开(公告)日：2001-10-09
申请号：US07931695
申请日：1992-08-18
申请人： Kent D. Harrison , Scott P. Thome , Peter T. Keith , Daniel O. Adams , William H. Penny
发明人： Kent D. Harrison , Scott P. Thome , Peter T. Keith , Daniel O. Adams , William H. Penny
IPC分类号： A61M2510
CPC分类号： A61M25/0105 , A61M25/0169 , A61M2025/0098
摘要： An apparatus and method for exchanging a first intravascular catheter of the over-the-wire type, such as an angioplasty balloon dilation catheter, with a second intravascular catheter of the over-the-wire type while leaving a guide wire in position in a desired vascular site. The apparatus is used in conjunction with a conventional guide catheter, a guide wire, and an interventional catheter that can be positioned intravascularly through a lumen of the guide catheter over the guide wire and past a distal end of the guide catheter to a desired vascular site. The apparatus includes an elongate shaft that can be removably positioned in the lumen of the guide catheter and has an actuation capability therein. A trapping member is located at a distal portion of the elongate shaft for releasably fixing the relative position of the guide wire with respect to the guide catheter. The fixing and releasing of the trapping member is effected by the actuation capability from outside the body of the patient so that a first interventional catheter can be exchanged for a second interventional catheter by trapping the guide wire position relative to the guide catheter while withdrawing the first interventional device and replacing it with another.
摘要翻译：一种用于与线上类型的第二血管内导管（例如血管成形术球囊扩张导管）交换诸如血管成形术球囊扩张导管的第一血管内导管的装置和方法，同时将引导线留在期望的位置血管部位。该装置与传统的导向导管，导丝和介入导管一起使用，其可以通过引导导管的导管血管内定位并且经过引导导管的远端定位到期望的血管部位。该装置包括细长轴，其可移除地定位在引导导管的内腔中并且在其中具有致动能力。捕获构件位于细长轴的远侧部分，用于可释放地固定导丝相对于导向导管的相对位置。捕获构件的固定和释放通过来自患者体外的致动能力来实现，使得可以通过相对于引导导管捕获引导线位置而将第一介入导管更换为第二介入导管，同时撤回第一介入导管介入装置，并用另一种装置代替。

2. 发明授权

US5843051A Intravascular device for coronary heart treatment 失效
公开(公告)号：US5843051A
公开(公告)日：1998-12-01
申请号：US602920
申请日：1996-03-21
申请人： Daniel O. Adams , Scott P. Thome
发明人： Daniel O. Adams , Scott P. Thome
IPC分类号： A61M25/01 , A61M29/02 , A61M5/00
CPC分类号： A61M25/0102 , A61M25/0172 , A61M2025/0004 , A61M2025/0047 , A61M25/104
摘要： An intravascular device having an elongated flexible tube sized for insertion into a coronary vessel beyond a distal end of a guide catheter. In use, the flexible tube has its proximal end within a guide catheter and has its distal end extending to a treatment site in a coronary artery. The device also including a push rod attached to a proximal end of the flexible tube to facilitate placement of the flexible tube within the coronary artery requiring treatment. In certain applications, the intravascular device is used as a drug (or other fluid) delivery device or as an aspiration device. In other applications, the intravascular device is used as a guiding means for placement of an angioplasty device, such as a guide wire or a balloon catheter. Additionally, an attachment tube may be provided which is designed to couple with a proximal end of the flexible tube to provide a continuous conduit for aspiration or fluid delivery to a treatment site in a coronary artery.

3. 发明授权

US5527292A Intravascular device for coronary heart treatment 失效
标题翻译：血管内装置用于冠心病治疗
公开(公告)号：US5527292A
公开(公告)日：1996-06-18
申请号：US303590
申请日：1994-09-09
申请人： Daniel O. Adams , Scott P. Thome
发明人： Daniel O. Adams , Scott P. Thome
IPC分类号： A61M25/01 , A61M29/02 , A61M5/00
CPC分类号： A61M25/0102 , A61M25/0172 , A61M2025/0004 , A61M2025/0047 , A61M25/104
摘要： An intravascular device having an elongated flexible tube sized for insertion into a coronary vessel beyond a distal end of a guide catheter. In use, the flexible tube has its proximal end within a guide catheter and has its distal end extending to a treatment site in a coronary artery. The device also including a push rod attached to a proximal end of the flexible tube to facilitate placement of the flexible tube within the coronary artery requiring treatment. In certain applications, the intravascular device is used as a drug (or other fluid) delivery device or as an aspiration device. In other applications, the intravascular device is used as a guiding means for placement of an angioplasty device, such as a guide wire or a balloon catheter. Additionally, an attachment tube may be provided which is designed to couple with a proximal end of the flexible tube to provide a continuous conduit for aspiration or fluid delivery to a treatment site in a coronary artery.
摘要翻译：一种具有细长柔性管的血管内装置，其尺寸适于插入超过引导导管的远端的冠状血管。在使用中，柔性管的近端具有导引导管，其远端延伸到冠状动脉的治疗部位。该装置还包括附接到柔性管的近端的推杆，以便于将柔性管置于需要治疗的冠状动脉内。在某些应用中，血管内装置用作药物（或其他流体）递送装置或用作抽吸装置。在其他应用中，血管内装置用作用于放置血管成形术装置（例如导丝或气囊导管）的引导装置。另外，可以设置附接管，其设计成与柔性管的近端连接以提供用于抽吸或液体输送到冠状动脉的治疗部位的连续导管。

4. 发明授权

US06183443B2 Expandable introducer sheath 失效
标题翻译：可扩展导引鞘
公开(公告)号：US06183443B2
公开(公告)日：2001-02-06
申请号：US09179231
申请日：1998-10-26
申请人： William F. Kratoska , Andrew G. Richardson , Sew-Wah Tay , Scott P. Thome , Peter T. Keith
发明人： William F. Kratoska , Andrew G. Richardson , Sew-Wah Tay , Scott P. Thome , Peter T. Keith
IPC分类号： A61M5178
CPC分类号： A61M25/0662 , A61B17/3439 , A61B2017/00867 , A61M2025/0024
摘要： The present invention comprises a method and device for providing an expandable introducer sheath. The method of employing the inventive device comprises inserting an elongate flexible tubular sheath into a vessel (with a proximal end of the sheath extending proximally outward through the skin), to slidably receive intravascular devices. When a larger size introducer sheath is desired, the sheath is manipulated while still in the vessel to expand its inner diameter to a larger size. In one embodiment, the sheath is made of a shape-memory polymer and is manipulated by inserting a heated mandrel (with an outer diameter larger than the inner diameter of the sheath) within the sheath to cause the sheath to expand to an inner diameter at least approximately equal to an outer diameter of the mandrel. The shape-memory polymer material ensures that the sheath will retain its expanded inner diameter. Alternatively, the sheath is formed from a telescoping multi-tubular arrangement of progressively larger tubes. In any case, insertion of the inventive sheath into the skin requires only a single small puncture which is then only expanded as needed while the sheath remains in place.
摘要翻译：本发明包括一种用于提供可扩展导引鞘的方法和装置。使用本发明的装置的方法包括将细长的柔性管状护套插入容器（护套的近端通过皮肤向近端延伸），以可滑动地容纳血管内装置。当需要更大尺寸的导引鞘时，在仍然在容器中操作护套以将其内径扩大到更大的尺寸。在一个实施例中，护套由形状记忆聚合物制成，并且通过将加热的心轴（具有大于护套的内径的外径大于外径）插入外壳中以使护套膨胀到内径至少近似等于心轴的外径。形状记忆聚合物材料确保护套将保持其膨胀的内径。或者，护套由逐渐变大的管的可伸缩多管布置形成。在任何情况下，将本发明的护套插入皮肤中仅需要一个小的穿刺，然后仅在护套保持就位的情况下根据需要扩张。

5. 发明授权

US6090072A Expandable introducer sheath 失效
标题翻译：可扩展导引鞘
公开(公告)号：US6090072A
公开(公告)日：2000-07-18
申请号：US615066
申请日：1996-03-14
申请人： William F. Kratoska , Sew-Wah Tay , Scott P. Thome , Peter T. Keith
发明人： William F. Kratoska , Sew-Wah Tay , Scott P. Thome , Peter T. Keith
IPC分类号： A61B17/00 , A61B17/34 , A61M25/06 , A61M25/00
CPC分类号： A61M25/0662 , A61B17/3439 , A61B2017/00867 , A61M2025/0024
摘要： The present invention comprises a method and device for providing an expandable introducer sheath. The method of employing the inventive device comprises inserting an elongate flexible tubular sheath into a vessel (with a proximal end of the sheath extending proximally outward through the skin), to slidably receive intravascular devices. When a larger size introducer sheath is desired, the sheath is manipulated while still in the vessel to expand its inner diameter to a larger size. In one embodiment, the sheath is made of a shape-memory polymer and is manipulated by inserting a heated mandrel (with an outer diameter larger than the inner diameter of the sheath) within the sheath to cause the sheath to expand to an inner diameter at least approximately equal to an outer diameter of the mandrel. The shape-memory polymer material ensures that the sheath will retain its expanded inner diameter. Alternatively, the sheath is formed from a telescoping multi-tubular arrangement of progressively larger tubes. In any case, insertion of the inventive sheath into the skin requires only a single small puncture which is then only expanded as needed while the sheath remains in place.
摘要翻译：本发明包括一种用于提供可扩展导引鞘的方法和装置。使用本发明的装置的方法包括将细长的柔性管状护套插入容器（护套的近端通过皮肤向近端延伸），以可滑动地容纳血管内装置。当需要更大尺寸的导引鞘时，在仍然在容器中操作护套以将其内径扩大到更大的尺寸。在一个实施例中，护套由形状记忆聚合物制成，并且通过将加热的心轴（具有大于护套的内径的外径大于外径）插入外壳中以使护套膨胀到内径至少近似等于心轴的外径。形状记忆聚合物材料确保护套将保持其膨胀的内径。或者，护套由逐渐变大的管的可伸缩多管布置形成。在任何情况下，将本发明的护套插入皮肤中仅需要一个小的穿刺，然后仅在护套保持就位的情况下根据需要扩张。

6. 发明授权

US06910787B2 Light guard 有权
标题翻译：守卫
公开(公告)号：US06910787B2
公开(公告)日：2005-06-28
申请号：US09929827
申请日：2001-08-14
申请人： Maxine C. Thome , Scott P. Thome
发明人： Maxine C. Thome , Scott P. Thome
IPC分类号： F21V15/02 , F21V15/00
CPC分类号： F21V15/02
摘要： A light guard of the present invention protects a light source mounted to a fixed surface. The light guard includes a base flange that is removably mountable to the fixed surface and a body portion that extends from the base flange for extending about and alongside the light source to prevent destruction of the light source.
摘要翻译：本发明的防护装置保护安装在固定表面上的光源。防护罩包括可拆卸地安装到固定表面的基部凸缘和从基部凸缘延伸的本体部分，用于在光源周围和旁边延伸以防止光源的破坏。

7. 发明授权

US5893870A Device and method for restricting venous flow for improved blood sampling 失效
标题翻译：用于限制静脉血流以改善血液采样的装置和方法
公开(公告)号：US5893870A
公开(公告)日：1999-04-13
申请号：US897488
申请日：1997-07-21
申请人： David J. Talen , Scott P. Thome
发明人： David J. Talen , Scott P. Thome
IPC分类号： A61B17/132 , A61M17/00
CPC分类号： A61B17/1322 , A61B17/1327
摘要： An apparatus used in a method of restricting venous flow in an extremity includes a first flexible, stretchable elongate band and a first flexible, stretchable loop fixed to a first end of the first band. A second loop sized to fit about the extremity is defined by passing a free end of the first band through the first loop. Upon pulling a free end of the first band through the first loop in a direction outward from the extremity, the first band stretches against the first loop, thereby causing the second loop to tighten about the extremity to restrict venous flow therethrough. A combination of frictional engagement and stretching of the first band and of the first loop against each other releasably secures the second loop about the extremity in its tightened position, thereby eliminating the need to hold the apparatus to maintain the tightened position. With venous flow restricted in the extremity, various procedures can be performed such as obtaining a blood sample with a conventional fingerstick puncture of the extremity.
摘要翻译：用于限制末端静脉流的方法中使用的装置包括第一柔性可拉伸细长带和固定到第一带第一端的第一柔性可拉伸环。通过使第一带的自由端穿过第一环来定义尺寸适于围绕末端的第二环。在从第一环向外拉动第一环的自由端穿过第一环时，第一带拉伸抵靠第一环，从而使第二环围绕末端紧固以限制静脉血流通过其中。第一带和第一环的摩擦接合和拉伸的结合彼此可释放地将第二环围绕其紧固位置的末端固定，从而消除了保持装置以保持紧固位置的需要。由于静脉流限制在末端，所以可以进行各种程序，例如用常规的手指针刺穿刺获得血液样本。

8. 发明授权

US06223085B1 Device and method for preventing restenosis 失效
标题翻译：用于预防再狭窄的装置和方法
公开(公告)号：US06223085B1
公开(公告)日：2001-04-24
申请号：US08852154
申请日：1997-05-06
申请人： Mitchell Dann , Scott P. Thome , Jonathan R. McGrath , Eric N. Rudie , Jonathan L. Flachman , Teruo T. Hirose
发明人： Mitchell Dann , Scott P. Thome , Jonathan R. McGrath , Eric N. Rudie , Jonathan L. Flachman , Teruo T. Hirose
IPC分类号： A61B1736
CPC分类号： A61B18/18 , A61B18/1492 , A61B18/1815 , A61B2017/22002 , A61B2017/22038 , A61B2017/22067 , A61B2018/00023 , A61B2018/00214 , A61B2018/00369 , A61B2018/00422 , A61B2018/1435 , A61B2018/183 , A61B2018/1838 , A61B2018/1846 , A61B2018/1861 , A61N5/045
摘要： A method and apparatus for reducing restenosis of a stenotic region of a blood vessel after performing a dilatation angioplasty treatment is disclosed. The method includes radiating microwave energy from a microwave antenna to kill a medial tissue layer of the blood vessel in the stenotic region. The radiation is applied during or after inflation of dilatation balloon to permanently dilate the stenotic region. When radiation is applied during dilatation of the stenotic region, the dilatation balloon forms a seal against the inner wall surface of the blood vessel to exclude blood in the vessel from contacting the stenotic region. The method preferably further includes cooling the blood circulating in the blood vessel about a shaft of the catheter with cooling fluid circulating within cooling lumens of the catheter and cooling an inner wall surface of the blood vessel in the stenotic region during the application of radiation to the medial cell layer. Finally, the method also preferably includes perfusing blood in the vessel through the catheter across the stenotic region during dilatation of the stenotic region to maintain circulation of blood through the blood vessel during the dilatation of the stenotic region.
摘要翻译：公开了一种用于在进行扩张血管成形术治疗后减少血管狭窄区域的再狭窄的方法和装置。该方法包括从微波天线辐射微波能量以杀死狭窄区域中血管的内侧组织层。在膨胀气球充气期间或之后施加辐射以永久扩张狭窄区域。当在狭窄区域的扩张期间施加辐射时，扩张气囊对血管的内壁表面形成密封，以排除血管中的血液与狭窄区域接触。该方法优选还包括：在导管冷却腔内循环的冷却流体冷却在血管周围的血液循环的血液，并且在将辐射施加到第二导管的过程中冷却狭窄区域中血管的内壁表面内侧细胞层。最后，该方法还优选包括在狭窄区域的扩张期间通过穿过狭窄区域的导管在血管中灌注血液，以在狭窄区域的扩张期间维持血液通过血管的循环。

9. 发明授权

US5555893A Shaft movement control apparatus 失效
标题翻译：轴运动控制装置
公开(公告)号：US5555893A
公开(公告)日：1996-09-17
申请号：US048492
申请日：1993-04-16
申请人： Steven S. Hackett , Roger N. Hastings , Arnold W. Thornton , Darlene A. Thometz , Kenneth R. Larson , Scott P. Thome , John W. Humphrey
发明人： Steven S. Hackett , Roger N. Hastings , Arnold W. Thornton , Darlene A. Thometz , Kenneth R. Larson , Scott P. Thome , John W. Humphrey
IPC分类号： A61M25/00 , A61M25/01 , A61M25/02 , A61B5/00
CPC分类号： A61M25/0169 , A61M25/0127 , A61M25/09041 , A61M2025/09116
摘要： The present invention is a device and method for controlling longitudinal movement of a tube relative to a shaft slidably disposed within the tube, especially in the catheterization of a patient. An operative segment on the shaft cooperates with an ancillary tool to create a coupling force field between the shaft and the tool. The tube can then be moved over the shaft while the coupling force field operates through the tube to restrict the movement of the shaft. In preferred embodiment, the shaft is a guide wire and the tube is a catheter with a lumen for slidably receiving the guide wire, while the coupling force field is created magnetically. In one embodiment, the operative segment is borne on a short guide wire extension which is selectively securable to a standard guide wire.
摘要翻译：本发明是一种用于控制管相对于可滑动地设置在管内的轴的纵向运动的装置和方法，特别是在患者的导管插入中。轴上的操作段与辅助工具协作以在轴和工具之间产生联接力场。然后，管可以在轴上移动，同时耦合力场通过管操作以限制轴的运动。在优选实施例中，所述轴是导丝，并且所述管是具有用于可滑动地接收所述导丝的内腔的导管，而所述耦合力场是磁力产生的。在一个实施例中，操作段承载在可选择性地固定到标准导丝的短导丝延伸部上。

10. 发明授权

US5470522A Method of molding Y-adapter with a sideport radius 失效
标题翻译： Y侧适配器侧边半径成型方法
公开(公告)号：US5470522A
公开(公告)日：1995-11-28
申请号：US273811
申请日：1994-07-12
申请人： Scott P. Thome , Thomas J. Holman
发明人： Scott P. Thome , Thomas J. Holman
IPC分类号： A61M39/10 , B29C45/36 , B29C45/44
CPC分类号： A61M39/10 , A61M2039/1077 , A61M2039/1083 , Y10S425/058
摘要： A method of molding the main body of a Y-adapter that has a straight passageway extending from one extremity to the other and an arcuate passageway that is generated along the arc of a circle. Core pins for the straight and arcuate passageways are placed in a mold such that they merges together to form a single, smooth lumen in the Y-adapter. The arcuate core pin can be withdrawn from the finished Y-adapter as a result of its circular arc.
摘要翻译：将具有从一个末端延伸到另一个末端的直通道的Y型适配器的主体成型的方法和沿着圆弧产生的弓形通道的方法。直线和弓形通道的芯针放置在模具中，使得它们合并在一起以在Y适配器中形成单个光滑的内腔。弓形芯销可以由于其圆弧而从完成的Y型适配器中取出。

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