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1. 发明申请

US20090024200A1 Drug Eluting Medical Device and Method 有权
标题翻译：药物洗脱医疗器械及方法
公开(公告)号：US20090024200A1
公开(公告)日：2009-01-22
申请号：US11780572
申请日：2007-07-20
申请人： Josiah Wilcox , Jeffrey Allen , Scott Doig , Rafaelita Brown
发明人： Josiah Wilcox , Jeffrey Allen , Scott Doig , Rafaelita Brown
IPC分类号： A61F2/84 , A61F2/82
CPC分类号： A61L31/16 , A61L31/10 , A61L2300/608 , A61L2420/08 , C08L5/02
摘要： A drug elution stent includes a stent framework and a drug elution portion disposed on the stent framework. The drug elution portion includes a first sugar layer disposed on the stent framework, at least one therapeutic agent layer disposed on the first sugar layer and a second sugar layer disposed on the at least one therapeutic agent layer. A method of manufacturing a drug elution stent includes the steps of providing a stent having a stent framework and coating at least a portion of the stent framework with a drug elution portion. The drug elution portion includes a first sugar layer disposed on the stent framework, at least one therapeutic agent layer disposed on the first sugar layer and a second sugar layer disposed on the at least one therapeutic agent layer
摘要翻译：药物洗脱支架包括支架框架和设置在支架框架上的药物洗脱部分。药物洗脱部分包括设置在支架框架上的第一糖层，设置在第一糖层上的至少一个治疗剂层和设置在至少一个治疗剂层上的第二糖层。制备药物洗脱支架的方法包括以下步骤：提供具有支架框架的支架，并用药物洗脱部分涂覆支架框架的至少一部分。药物洗脱部分包括设置在支架框架上的第一糖层，设置在第一糖层上的至少一个治疗剂层和设置在至少一个治疗剂层上的第二糖层

2. 发明授权

US08070798B2 Drug eluting medical device and method 有权
标题翻译：药物洗脱医疗器械及方法
公开(公告)号：US08070798B2
公开(公告)日：2011-12-06
申请号：US11780572
申请日：2007-07-20
申请人： Josiah Wilcox , Jeffrey Allen , Scott Doig , Rafaelita Brown
发明人： Josiah Wilcox , Jeffrey Allen , Scott Doig , Rafaelita Brown
IPC分类号： A61F2/82
CPC分类号： A61L31/16 , A61L31/10 , A61L2300/608 , A61L2420/08 , C08L5/02
摘要： A drug elution stent includes a stent framework and a drug elution portion disposed on the stent framework. The drug elution portion includes a first sugar layer disposed on the stent framework, at least one therapeutic agent layer disposed on the first sugar layer and a second sugar layer disposed on the at least one therapeutic agent layer. A method of manufacturing a drug elution stent includes the steps of providing a stent having a stent framework and coating at least a portion of the stent framework with a drug elution portion. The drug elution portion includes a first sugar layer disposed on the stent framework, at least one therapeutic agent layer disposed on the first sugar layer and a second sugar layer disposed on the at least one therapeutic agent layer.
摘要翻译：药物洗脱支架包括支架框架和设置在支架框架上的药物洗脱部分。药物洗脱部分包括设置在支架框架上的第一糖层，设置在第一糖层上的至少一个治疗剂层和设置在至少一个治疗剂层上的第二糖层。制备药物洗脱支架的方法包括以下步骤：提供具有支架框架的支架，并用药物洗脱部分涂覆支架框架的至少一部分。药物洗脱部分包括设置在支架框架上的第一糖层，设置在第一糖层上的至少一个治疗剂层和设置在至少一个治疗剂层上的第二糖层。

3. 发明申请

US20080249599A1 Stent With Therapeutic Agent Delivery Structures in Low Strain Regions 审中-公开
标题翻译：在低应变区域中具有治疗剂递送结构的支架
公开(公告)号：US20080249599A1
公开(公告)日：2008-10-09
申请号：US11696816
申请日：2007-04-05
申请人： Jeffrey Allen , Scott Doig , Matthew J. Birdsall , Darrel Untereker
发明人： Jeffrey Allen , Scott Doig , Matthew J. Birdsall , Darrel Untereker
IPC分类号： A61F2/82
CPC分类号： A61F2/915 , A61F2/91 , A61F2002/91558 , A61F2250/0023 , A61F2250/0067
摘要： A system for treating abnormalities of the cardiovascular system includes a stent having a plurality of therapeutic agent-carrying regions and non therapeutic agent-carrying regions. The therapeutic agent-carrying regions are located within low strain regions of the stent and the non therapeutic agent-carrying regions are located within high strain regions of the stent. Another embodiment of the invention includes a method of manufacturing a therapeutic agent-carrying stent comprising forming a stent framework and applying a formulation containing one or more therapeutic agents to the stent framework while preventing the therapeutic agents from contacting the high strain regions of the stent framework.
摘要翻译：用于治疗心血管系统异常的系统包括具有多个治疗剂携带区域和非治疗剂携带区域的支架。治疗剂携带区域位于支架的低应变区域内，并且非治疗剂携带区域位于支架的高应变区域内。本发明的另一个实施方案包括制备治疗剂携带支架的方法，包括形成支架框架并将含有一种或多种治疗剂的制剂施用于支架框架，同时防止治疗剂接触支架框架的高应变区域。

4. 外观设计

USD714453S1 Hand held unit for diagnostics or measurement 有权
标题翻译：用于诊断或测量的手持单元
公开(公告)号：USD714453S1
公开(公告)日：2014-09-30
申请号：US29430814
申请日：2012-08-30
申请人： Jonathan David Mongin , David Farquhar , William W. Wells, Jr. , Richard L. Fowler , Jeffrey Allen , Devin Lee Moore , Brian Andrew Wong-Shui , Jesse Marie Newton
设计人： Jonathan David Mongin , David Farquhar , William W. Wells, Jr. , Richard L. Fowler , Jeffrey Allen , Devin Lee Moore , Brian Andrew Wong-Shui , Jesse Marie Newton

5. 发明授权

US08562673B2 Stented transcatheter prosthetic heart valve delivery system and method 有权
公开(公告)号：US08562673B2
公开(公告)日：2013-10-22
申请号：US12886975
申请日：2010-09-21
申请人： Hubert Yeung , John Shanahan , Joshua Dwork , Adam Shipley , Jeffrey Allen , Susheel Deshmukh , Kishore Udipi , Ya Guo
发明人： Hubert Yeung , John Shanahan , Joshua Dwork , Adam Shipley , Jeffrey Allen , Susheel Deshmukh , Kishore Udipi , Ya Guo
IPC分类号： A61F2/24
CPC分类号： A61F2/2436 , A61F2/2412 , A61F2/2418 , A61F2/2427 , A61F2/966 , A61F2002/9528 , A61F2002/9534 , A61F2220/005 , A61F2230/0054 , A61F2230/0067 , A61F2230/008
摘要： A percutaneous stented valve delivery device including an inner shaft, a sheath, and a delivery capsule. The sheath slidably receives the inner shaft. A capsule proximal zone is attached to the sheath. A capsule distal zone is configured to transition between normal and flared states. A diameter of the distal zone is greater in the flared state, and the capsule includes a shape memory component that naturally assumes the normal state. The device is operable to perform a reversible partial deployment procedure in which a portion of the prosthesis is exposed distal the capsule and allowed to radially expand. Subsequently, with distal advancement of the capsule, the distal zone transitions to the flared state and imparts a collapsing force onto the prosthesis, causing the prosthesis to radially collapse and become recaptured within the delivery capsule. The capsule can include a laser cut tube encapsulated by a polymer.

6. 发明授权

US08317588B2 Apparatus for providing amusement 有权
公开(公告)号：US08317588B2
公开(公告)日：2012-11-27
申请号：US12849022
申请日：2010-08-03
申请人： John G. Kroeckel , Gennady I. Soliterman , Bryan M. Kelly , Dennis Lockard , Jeffrey C. Tallcott , Jeffrey Allen , Robert Luciano , Robert Luciano, Sr., legal representative
发明人： John G. Kroeckel , Gennady I. Soliterman , Bryan M. Kelly , Dennis Lockard , Jeffrey C. Tallcott , Jeffrey Allen , Robert Luciano
IPC分类号： G06F17/00
CPC分类号： G07F17/3295 , G07F17/32 , G07F17/3244 , G07F17/3248 , G07F17/3293 , G07F17/34
摘要： Certain non-limiting exemplary embodiments are taught which include a game comprising, a digital processor, digital storage coupled to the digital processor for storing instructions, a display coupled to the digital processor displaying a first plurality of indicia arranged in a plurality of rows and a plurality of columns such that there are a plurality of paylines through a contiguous plurality of indicia, a user interface coupled to the digital processor to select a subset of the first plurality of indicia taken along at least one column and to initiate a display of a second plurality of indicia which includes the selected subset of the first plurality of indicia on the display, and an award dispenser providing an award which is at least as large as the largest award associated with the plurality of paylines.

7. 发明授权

US08051826B2 Injection system for an internal combustion engine 有权
标题翻译：内燃机喷射系统
公开(公告)号：US08051826B2
公开(公告)日：2011-11-08
申请号：US12038214
申请日：2008-02-27
申请人： Jeffrey Allen , Paul Bartholomew Ravenhill , Steven Barraclough
发明人： Jeffrey Allen , Paul Bartholomew Ravenhill , Steven Barraclough
IPC分类号： F01M1/16
CPC分类号： F01M1/14 , F01M1/08 , F01M1/16 , F01N3/208 , F01N3/36 , F01N2560/021 , F01N2560/06 , F01N2610/1433 , F01N2610/146 , F01N2900/08 , F02M51/04 , F02M59/462 , F04B17/046 , Y02A50/2325 , Y02T10/24
摘要： The present invention relates to an internal combustion engine having an injector which functions as a positive displacement pump and dispenses an amount of lubricant fixed for each and every operation of the injector. The fluid dispensed could be a lubricant delivered directly to crankshaft bearings, camshaft bearings, tappets or cylinder sleeve. Alternatively the fluid could be fuel, water or urea delivered to an exhaust system upstream of a catalytic converter. The injector can have a one-way valve with a valve element having a domed or conical surface for directing fluid flow across a sharp edge which induces turbulence in the fluid flow.
摘要翻译：本发明涉及一种内燃机，其具有用作正排量泵的喷射器，并且分配针对喷射器的每次操作而固定的润滑剂量。分配的流体可以是直接输送到曲轴轴承，凸轮轴轴承，挺杆或气缸套的润滑剂。或者，流体可以是输送到催化转化器上游的排气系统的燃料，水或尿素。喷射器可以具有单向阀，阀单元具有圆顶或圆锥形表面，用于引导流体流过锋利的边缘，这引起流体流动中的湍流。

8. 发明申请

US20110217784A1 METHOD FOR PRODUCING SOLUBLE RECOMBINANT INTERFERON PROTEIN WITHOUT DENATURING 有权
标题翻译：生产可溶性重组干扰素蛋白的方法，无需去除
公开(公告)号：US20110217784A1
公开(公告)日：2011-09-08
申请号：US13039183
申请日：2011-03-02
申请人： Jeffrey Allen , Ping-Hua Feng , Anant Patkar , Keith L. Haney , Lawrence Chew , Lei Lei Phokham Sengchanthalangsy
发明人： Jeffrey Allen , Ping-Hua Feng , Anant Patkar , Keith L. Haney , Lawrence Chew , Lei Lei Phokham Sengchanthalangsy
IPC分类号： G01N33/68 , C07K1/14 , C12P21/00
CPC分类号： C12P21/02 , A61K38/21 , C07K14/555
摘要： The present invention relates to the field of recombinant protein production in bacterial hosts. It further relates to extraction of soluble, active recombinant protein from an insoluble fraction without the use of denaturation and without the need for a refolding step. In particular, the present invention relates to a production process for obtaining high levels a soluble recombinant Type 1 interferon protein from a bacterial host.
摘要翻译：本发明涉及细菌宿主中重组蛋白质生产领域。它还涉及从不溶性级分中提取可溶性活性重组蛋白，而不需要使用变性，而不需要重折叠步骤。特别地，本发明涉及从细菌宿主获得高水平的可溶性重组型1型干扰素蛋白的制备方法。

9. 发明申请

US20110184253A1 Life support and microclimate integrated system and process with internal and external active heating 有权
标题翻译：生活支持和微气候综合系统和过程与内部和外部主动加热
公开(公告)号：US20110184253A1
公开(公告)日：2011-07-28
申请号：US12931078
申请日：2011-01-24
申请人： Ian Archer , Jeffrey Allen , Kevin Kankolenski , Manus Michael O'Donnell , Lucas Mesmer
发明人： Ian Archer , Jeffrey Allen , Kevin Kankolenski , Manus Michael O'Donnell , Lucas Mesmer
IPC分类号： A61B5/0205 , A61M16/00 , A61B5/01 , A61B5/1455 , A61B5/024
CPC分类号： A61F7/0085 , A61B5/02055 , A61B5/024 , A61B5/14551 , A61F7/00 , A61F7/0053 , A61F7/0097 , A61F7/02 , A61F7/08 , A61F2007/0054 , A61F2007/0087 , A61F2007/0096 , A61F2007/0225 , A61F2007/0231 , A61F2007/0234 , A61M5/44 , A61M16/00 , A61M16/022 , A61M16/10 , A61M16/14 , A61M19/00 , A61M2205/3606 , A61M2205/366
摘要： The present invention of one embodiment includes a combined microclimate, thermal management, life-support system for care of patient and system for measurement of vital signs. The system of one embodiment, provides active external heating and simultaneously provides active internal heating.
摘要翻译：一个实施例的本发明包括组合的微气候，热管理，用于照顾患者的生命支持系统和用于测量生命体征的系统。一个实施例的系统提供主动的外部加热并同时提供主动的内部加热。

10. 发明授权

US07976373B2 Apparatus for providing amusement 有权
标题翻译：提供娱乐的装置
公开(公告)号：US07976373B2
公开(公告)日：2011-07-12
申请号：US11651918
申请日：2007-01-09
申请人： John G. Kroeckel , Gennady I. Soliterman , Bryan M. Kelly , Dennis Lockard , Jeffrey C. Tallcott , Jeffrey Allen , Robert Luciano
发明人： John G. Kroeckel , Gennady I. Soliterman , Bryan M. Kelly , Dennis Lockard , Jeffrey C. Tallcott , Jeffrey Allen , Robert Luciano
IPC分类号： G06F17/00
CPC分类号： G07F17/3295 , G07F17/32 , G07F17/3244 , G07F17/3248 , G07F17/3293 , G07F17/34
摘要： Certain non-limiting exemplary embodiments are taught which include a game comprising, a digital processor, digital storage coupled to the digital processor for storing instructions, a display coupled to the digital processor displaying a first plurality of indicia arranged in a plurality of rows and a plurality of columns such that there are a plurality of paylines through a contiguous plurality of indicia, a user interface coupled to the digital processor to select a subset of the first plurality of indicia taken along at least one column and to initiate a display of a second plurality of indicia which includes the selected subset of the first plurality of indicia on the display, and an award dispenser providing an award which is at least as large as the largest award associated with the plurality of paylines.
摘要翻译：教导了包括游戏的某些非限制性示例性实施例，该游戏包括数字处理器，耦合到数字处理器的用于存储指令的数字存储器，耦合到数字处理器的显示器，显示以多行排列的第一多个标记，以及多个列，使得通过连续的多个标记存在多个支付线;用户界面，其耦合到所述数字处理器，以选择沿着至少一列取得的所述第一多个标记的子集，并且开始显示第二个多个标记，其包括显示器上的第一多个标记的选定子集，以及授权分配器，其提供至少与与多个支付线相关联的最大奖励一样大的奖励。

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