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1. 发明申请

US20110098804A1 STENTED TRANSCATHETER PROSTHETIC HEART VALVE DELIVERY SYSTEM AND METHOD 有权
公开(公告)号：US20110098804A1
公开(公告)日：2011-04-28
申请号：US12886975
申请日：2010-09-21
申请人： Hubert Yeung , John Shanahan , Joshua Dwork , Adam Shipley , Jeffrey Allen , Susheel Deshmukh , Kishore Udipi , Ya Guo
发明人： Hubert Yeung , John Shanahan , Joshua Dwork , Adam Shipley , Jeffrey Allen , Susheel Deshmukh , Kishore Udipi , Ya Guo
IPC分类号： A61F2/24
CPC分类号： A61F2/2436 , A61F2/2412 , A61F2/2418 , A61F2/2427 , A61F2/966 , A61F2002/9528 , A61F2002/9534 , A61F2220/005 , A61F2230/0054 , A61F2230/0067 , A61F2230/008
摘要： A percutaneous stented valve delivery device including an inner shaft, a sheath, and a delivery capsule. The sheath slidably receives the inner shaft. A capsule proximal zone is attached to the sheath. A capsule distal zone is configured to transition between normal and flared states. A diameter of the distal zone is greater in the flared state, and the capsule includes a shape memory component that naturally assumes the normal state. The device is operable to perform a reversible partial deployment procedure in which a portion of the prosthesis is exposed distal the capsule and allowed to radially expand. Subsequently, with distal advancement of the capsule, the distal zone transitions to the flared state and imparts a collapsing force onto the prosthesis, causing the prosthesis to radially collapse and become recaptured within the delivery capsule. The capsule can include a laser cut tube encapsulated by a polymer.
摘要翻译：一种经皮支架置入的瓣膜输送装置，包括内轴，护套和输送胶囊。护套可滑动地容纳内轴。胶囊近端区域附接到护套。胶囊远端区域被配置为在正常和扩张状态之间转变。远端区域的直径在扩张状态下较大，并且胶囊包括自然地呈现正常状态的形状记忆组件。该装置可操作以执行可逆部分展开过程，其中假体的一部分暴露在胶囊的远端并允许径向扩张。随后，随着胶囊的远端前进，远侧区域转变到扩张状态并且将塌陷力施加到假体上，导致假体径向折叠并在输送胶囊内重新捕获。胶囊可以包括由聚合物包封的激光切割管。

2. 发明授权

US08562673B2 Stented transcatheter prosthetic heart valve delivery system and method 有权
公开(公告)号：US08562673B2
公开(公告)日：2013-10-22
申请号：US12886975
申请日：2010-09-21
申请人： Hubert Yeung , John Shanahan , Joshua Dwork , Adam Shipley , Jeffrey Allen , Susheel Deshmukh , Kishore Udipi , Ya Guo
发明人： Hubert Yeung , John Shanahan , Joshua Dwork , Adam Shipley , Jeffrey Allen , Susheel Deshmukh , Kishore Udipi , Ya Guo
IPC分类号： A61F2/24
CPC分类号： A61F2/2436 , A61F2/2412 , A61F2/2418 , A61F2/2427 , A61F2/966 , A61F2002/9528 , A61F2002/9534 , A61F2220/005 , A61F2230/0054 , A61F2230/0067 , A61F2230/008
摘要： A percutaneous stented valve delivery device including an inner shaft, a sheath, and a delivery capsule. The sheath slidably receives the inner shaft. A capsule proximal zone is attached to the sheath. A capsule distal zone is configured to transition between normal and flared states. A diameter of the distal zone is greater in the flared state, and the capsule includes a shape memory component that naturally assumes the normal state. The device is operable to perform a reversible partial deployment procedure in which a portion of the prosthesis is exposed distal the capsule and allowed to radially expand. Subsequently, with distal advancement of the capsule, the distal zone transitions to the flared state and imparts a collapsing force onto the prosthesis, causing the prosthesis to radially collapse and become recaptured within the delivery capsule. The capsule can include a laser cut tube encapsulated by a polymer.

3. 发明申请

US20120303111A1 Attachment Mechanism for Stent Release 有权
公开(公告)号：US20120303111A1
公开(公告)日：2012-11-29
申请号：US13572319
申请日：2012-08-10
申请人： Joshua Dwork , Hubert Yeung , Adam Shipley
发明人： Joshua Dwork , Hubert Yeung , Adam Shipley
IPC分类号： A61F2/84
CPC分类号： A61F2/95 , A61F2/966 , A61F2002/9505
摘要： An attachment mechanism for coupling a stent to a delivery system is disclosed. The attachment mechanism is configured to pivot relative to an inner shaft assembly of the delivery system in order to release the stent from the delivery system.

4. 发明申请

US20120022628A1 Attachment Mechanism for Stent Release 有权
标题翻译：支架释放机构
公开(公告)号：US20120022628A1
公开(公告)日：2012-01-26
申请号：US12842496
申请日：2010-07-23
申请人： Joshua Dwork , Hubert Yeung , Adam Shipley
发明人： Joshua Dwork , Hubert Yeung , Adam Shipley
IPC分类号： A61F2/84
CPC分类号： A61F2/966 , A61F2/95 , A61F2002/9505
摘要： An attachment mechanism for coupling a stent to a delivery system is disclosed. The attachment mechanism is configured to pivot relative to an inner shaft assembly of the delivery system in order to release the stent from the delivery system.
摘要翻译：公开了一种用于将支架耦合到输送系统的附接机构。附接机构构造成相对于输送系统的内轴组件枢转，以将支架从输送系统释放。

5. 发明授权

US09192495B2 Attachment mechanism for stent release 有权
标题翻译：支架释放机构
公开(公告)号：US09192495B2
公开(公告)日：2015-11-24
申请号：US13572319
申请日：2012-08-10
申请人： Joshua Dwork , Hubert Yeung , Adam Shipley
发明人： Joshua Dwork , Hubert Yeung , Adam Shipley
IPC分类号： A61F2/95 , A61F2/966
CPC分类号： A61F2/95 , A61F2/966 , A61F2002/9505
摘要： An attachment mechanism for coupling a stent to a delivery system is disclosed. The delivery system includes an inner shaft assembly. The attachment mechanism is configured to pivot relative to the inner shaft assembly of the delivery system in order to release the stent from the delivery system upon retraction of a delivery sheath capsule compressively containing the stent.
摘要翻译：公开了一种用于将支架耦合到输送系统的附接机构。输送系统包括内轴组件。附接机构构造成相对于输送系统的内轴组件枢转，以便在收缩包含该支架的输送护套胶囊收回时将支架从输送系统中释放。

6. 发明授权

US08876878B2 Attachment mechanism for stent release 有权
标题翻译：支架释放机构
公开(公告)号：US08876878B2
公开(公告)日：2014-11-04
申请号：US12842496
申请日：2010-07-23
申请人： Joshua Dwork , Hubert Yeung , Adam Shipley
发明人： Joshua Dwork , Hubert Yeung , Adam Shipley
IPC分类号： A61F2/97 , A61F2/95 , A61F2/966
CPC分类号： A61F2/966 , A61F2/95 , A61F2002/9505
摘要： An attachment mechanism for coupling a stent to a delivery system is disclosed. The attachment mechanism is configured to pivot relative to an inner shaft assembly of the delivery system in order to release the stent from the delivery system.
摘要翻译：公开了一种用于将支架耦合到输送系统的附接机构。附接机构构造成相对于输送系统的内轴组件枢转，以将支架从输送系统释放。

7. 发明授权

US08876893B2 Transcatheter prosthetic heart valve delivery device with passive trigger release 有权
标题翻译：经导管假体心脏瓣膜输送装置，被动触发释放
公开(公告)号：US08876893B2
公开(公告)日：2014-11-04
申请号：US13095147
申请日：2011-04-27
申请人： Joshua Dwork , Glenn Stante , Adam Shipley
发明人： Joshua Dwork , Glenn Stante , Adam Shipley
IPC分类号： A61F2/24
CPC分类号： A61F2/2436 , A61F2/2418 , A61F2002/9505 , A61F2230/0054 , A61F2230/008
摘要： A delivery device for percutaneously deploying a prosthetic valve includes a sheath, an inner shaft, and a release assembly. The release assembly is disposed between the sheath and the inner shaft, and includes a retraction member, a release member, and a retention member. The retraction member can self-retract in length from an extended condition to a retracted condition. The release member can self-expand from a compressed condition to an expanded condition. The retention member is distal the release member. In a delivery state, the sheath end is distal the retention member, the release member is in the compressed condition and the retraction member in the extended condition to retain the prosthesis. In a deployment state, the sheath end is positioned to permit the release member to self-transition to the expanded condition, allowing the retraction member to self-transition to the retracted condition and release the prosthesis.
摘要翻译：用于经皮部署假性瓣膜的输送装置包括护套，内轴和释放组件。释放组件设置在护套和内轴之间，并且包括缩回构件，释放构件和保持构件。缩回构件可以从伸长状态自动缩回到缩回状态。释放构件可以从压缩状态自膨胀到膨胀状态。保持构件远离释放构件。在输送状态下，护套端部处于保持构件的远侧，释放构件处于压缩状态，并且延伸构件处于延伸状态以保持假体。在展开状态中，护套端部被定位成允许释放构件自我转变到扩张状态，允许收回构件自我转变到缩回状态并释放假体。

8. 发明申请

US20110264203A1 Transcatheter Prosthetic Heart Valve Delivery Device With Passive Trigger Release 有权
标题翻译：经导管假人心脏瓣膜输送装置与被动触发释放
公开(公告)号：US20110264203A1
公开(公告)日：2011-10-27
申请号：US13095147
申请日：2011-04-27
申请人： Joshua Dwork , Glenn Stante , Adam Shipley
发明人： Joshua Dwork , Glenn Stante , Adam Shipley
IPC分类号： A61F2/24
CPC分类号： A61F2/2436 , A61F2/2418 , A61F2002/9505 , A61F2230/0054 , A61F2230/008
摘要： A delivery device for percutaneously deploying a prosthetic valve includes a sheath, an inner shaft, and a release assembly. The release assembly is disposed between the sheath and the inner shaft, and includes a retraction member, a release member, and a retention member. The retraction member can self-retract in length from an extended condition to a retracted condition. The release member can self-expand from a compressed condition to an expanded condition. The retention member is distal the release member. In a delivery state, the sheath end is distal the retention member, the release member is in the compressed condition and the retraction member in the extended condition to retain the prosthesis. In a deployment state, the sheath end is positioned to permit the release member to self-transition to the expanded condition, allowing the retraction member to self-transition to the retracted condition and release the prosthesis.
摘要翻译：用于经皮部署假性瓣膜的输送装置包括护套，内轴和释放组件。释放组件设置在护套和内轴之间，并且包括缩回构件，释放构件和保持构件。缩回构件可以从伸长状态自动缩回到缩回状态。释放构件可以从压缩状态自膨胀到膨胀状态。保持构件远离释放构件。在输送状态下，护套端部处于保持构件的远侧，释放构件处于压缩状态，并且延伸构件处于延伸状态以保持假体。在展开状态中，护套端部被定位成允许释放构件自转过渡到膨胀状态，允许收回构件自转过渡到缩回状态并释放假体。

9. 发明申请

US20110264198A1 Transcatheter Prosthetic Heart Valve Delivery System and Method with Controlled Expansion of Prosthetic Heart Valve 有权
标题翻译：经导管假性心脏瓣膜输送系统及心脏瓣膜控制膨胀的方法
公开(公告)号：US20110264198A1
公开(公告)日：2011-10-27
申请号：US13091917
申请日：2011-04-21
申请人： Robert J. Murray, III , Charles Tabor , Andrew Crisman , Adam Shipley
发明人： Robert J. Murray, III , Charles Tabor , Andrew Crisman , Adam Shipley
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/2436 , A61F2/2439 , A61F2230/0054
摘要： A delivery system for use with a prosthetic heart valve having a stent frame to which a valve structure is attached includes a shaft assembly including a distal end, an intermediate portion, and a first coupling structure disposed near the distal end and configured to be coupled to a distal end of the prosthetic heart valve via a first tether. A sheath assembly defines a lumen sized to slidably receive the shaft assembly. The delivery system is configured to transition from a loaded state in which the sheath assembly encompasses the prosthetic heart valve to a deployed state in which the sheath assembly is withdrawn from the prosthetic heart valve. The first coupling structure is configured to be manipulated in a first direction to provide a controlled expansion or contraction of the distal end of the prosthetic heart valve.
摘要翻译：一种与具有附接有阀结构的支架框架的假体心脏瓣膜一起使用的输送系统包括：轴组件，包括远端，中间部分和设置在远端附近的第一联接结构，经由第一系绳的假体心脏瓣膜的远端。护套组件限定尺寸为可滑动地容纳轴组件的内腔。输送系统被配置成从其中护套组件包围假体心脏瓣膜的负载状态转变到其中护套组件从假体心脏瓣膜抽出的展开状态。第一联接结构构造成在第一方向上被操纵以提供假体心脏瓣膜的远端的可控膨胀或收缩。

10. 发明申请

US20110251681A1 Transcatheter Prosthetic Heart Valve Delivery System with Recapturing Feature and Method 有权
标题翻译：经导管假手术心脏瓣膜输送系统具有恢复特征和方法
公开(公告)号：US20110251681A1
公开(公告)日：2011-10-13
申请号：US12757138
申请日：2010-04-09
申请人： Adam Shipley , John P. Shanahan , Andrew Crisman
发明人： Adam Shipley , John P. Shanahan , Andrew Crisman
IPC分类号： A61F2/24
CPC分类号： A61F2/2436 , A61F2/2418 , A61F2/2427 , A61F2/243 , A61F2002/9517 , A61F2002/9534
摘要： A delivery system for percutaneously deploying a prosthetic heart valve. The system includes an inner shaft assembly, a delivery sheath capsule and a handle maintaining a first actuator and a second actuator. The capsule is configured to compressively retain the prosthetic heart valve over the inner shaft assembly. The first actuator is operated to proximally retract the delivery sheath capsule and expose the prosthetic heart valve relative to the capsule. The second actuator is operated to proximally retract the prosthetic heart valve by transmitting forces to the inner shaft assembly.
摘要翻译：用于经皮部署假性心脏瓣膜的输送系统。该系统包括内轴组件，输送护套胶囊和保持第一致动器和第二致动器的手柄。胶囊构造成将假体心脏瓣膜压缩地保持在内轴组件上。第一致动器被操作以向近端缩回输送护套胶囊并相对于胶囊暴露假体心脏瓣膜。操作第二致动器以通过将力传递到内轴组件来近侧缩回假体心脏瓣膜。

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