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    • 1. 发明申请
    • Functionalized poly(ethylene glycol)
    • 官能化聚(乙二醇)
    • US20070238656A1
    • 2007-10-11
    • US11400935
    • 2006-04-10
    • John HarderJeffrey Leon
    • John HarderJeffrey Leon
    • A61K38/00
    • C08G65/329C08G65/334C08G65/3344C08G65/3348
    • The present invention relates to a bi-functional compound containing a linking material, and a particle comprising a linking material, and a linking material comprising a polyethylene glycol macromonomer backbone with a radical polymerizable group at one end of the macromonomer backbone and a different reactive chemical functionality at the other end of the macromonomer backbone, according to Formula I: wherein X is CH3, CN or H; Y is O, NR1, or S; L is a linking group or spacer; FG is a functional group; n is greater than 4 and less than 1000; and wherein R1 and R2 are independently selected from substituted or unsubstituted alkyl, aryl, or heteroyl.
    • 本发明涉及包含连接材料的双功能化合物和包含连接材料的颗粒,以及包含在大分子单体骨架的一端具有自由基聚合性基团的聚乙二醇大分子单体骨架和不同的反应性化学物质的连接材料 在大分子单体骨架的另一端的官能团,根据式I:其中X是CH 3,CN或H; Y是O,NR 1或S; L是连接基团或间隔基; FG是功能组; n大于4且小于1000; 并且其中R 1和R 2独立地选自取代或未取代的烷基,芳基或杂基。
    • 2. 发明申请
    • Nanogel-based contrast agents for optical molecular imaging
    • 基于Nanogel的光学分子成像造影剂
    • US20070237821A1
    • 2007-10-11
    • US11401343
    • 2006-04-10
    • Jeffrey LeonJames BennettTiecheng QiaoJohn HarderThomas MoureyGary SlaterLijun Dai
    • Jeffrey LeonJames BennettTiecheng QiaoJohn HarderThomas MoureyGary SlaterLijun Dai
    • A61K9/14
    • A61K49/0093A61K47/6903A61K47/6933A61K49/0032A61K49/0073B82Y5/00
    • The present invention relates to a nanogel comprising a polymer network of repetitive, crosslinked, ethylenically unsaturated monomers of Formula I: (X)m-(Y)n-(Z)o  Formula I wherein X is a water-soluble monomer containing ionic or hydrogen bonding moieties; Y is a water-soluble macromonomer containing repetitive hydrophilic units bound to a polymerizeable ethylenically unsaturated group; Z is a multifunctional crosslinking monomer; m ranges from 50-90 mol %; n ranges from 2-30 mol %; and o range from 1-15 mol % and a method for preparing a nanogel comprising preparing a header composition of a mixture of monomers X, Y, and Z, and a first portion of initiators in water; preparing a reactor composition of a second portion initiators, surfactant, and water; bringing the reactor composition to the polymerization temperature; holding the reactor composition at the polymerization temperature, and adding the header composition to the reactor composition to form a nanogel of Formula I.
    • 本发明涉及纳米凝胶,其包含式I的重复,交联,烯键式不饱和单体的聚合物网络:<?在线公式描述=“在线式”末端=“铅”→(X)m- (Y)n-(Z)o式I <?in-line-formula description =“In-line Formulas”end =“tail”?>其中X是含有离子或氢键结构部分的水溶性单体; Y是含有与可聚合烯属不饱和基团结合的重复亲水单元的水溶性大分子单体; Z是多功能交联单体; m范围为50-90摩尔%; n范围为2-30mol%; 其范围为1-15mol%,制备纳米凝胶的方法包括制备单体X,Y和Z的混合物的头部组合物和在水中的第一部分引发剂; 制备第二部分引发剂,表面活性剂和水的反应器组合物; 使反应器组成达到聚合温度; 将反应器组合物保持在聚合温度,并将集管组合物加入到反应器组合物中以形成式I的纳米凝胶。
    • 6. 发明申请
    • Switchable polymer printing plates with carbon bearing ionic and steric stabilizing groups
    • 具有碳离子和立体稳定基团的可切换聚合物印版
    • US20050260509A1
    • 2005-11-24
    • US10852552
    • 2004-05-24
    • Paul WestJeffrey LeonNicki Miller
    • Paul WestJeffrey LeonNicki Miller
    • B41C1/10G03C3/00
    • B41C1/1041
    • The present invention provides an imageable member having an imageable layer including a heat-sensitive ionomer characterized by a net positive or negative charge, and a photothermal conversion material. The photothermal conversion material includes carbonaceous particles having thereon both an organic moiety including an ionic substituent having like charge as the ionomer, and a group represented by the formula —X—[NIon]p-Rterminal; wherein X represents an aromatic group or an alkyl group, NIon represents a non-ionic, non-ionizable group, Rterminal represents hydrogen, an aromatic group, an alkoxy group, or an alkyl group, and p is an integer from 1 to about 500. The heat-sensitive ionomer and modified carbonaceous particles can be formulated in water or water-miscible solvents without agglomeration. Imageable members utilizing the modified carbonaceous particles as a photothermal conversion material exhibit acceptable optical density and exposure speed, and imaged members made therefrom exhibit excellent background performance.
    • 本发明提供了一种可成像的构件,其具有包括以正正电荷或负电荷为特征的热敏离聚物的可成像层和光热转换材料。 光热转换材料包括其上具有包含具有类似电荷的离子取代基的有机部分作为离聚物的碳质粒子和由式<β在线公式描述=“在线配方”中所示的基团末端=“铅 - - - - - - - - - - - - - <?in-line-formula description =“In-line formula”end =“tail”?>其中X表示芳族基团或烷基,NIon表示非离子型,不可离子化的基团R 代表氢,芳基,烷氧基或烷基,p是1至约500的整数。热敏离聚物和改性碳质颗粒可配制成水或水混溶性溶剂 无聚集。 利用改性碳质颗粒作为光热转换材料的可成像构件表现出可接受的光密度和曝光速度,并由其制成的成像构件表现出优异的背景性能。