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1. 发明申请

US20060293396A1 Amine polymer-modified nanoparticulate carriers 审中-公开
标题翻译：胺聚合物改性纳米颗粒载体
公开(公告)号：US20060293396A1
公开(公告)日：2006-12-28
申请号：US11165849
申请日：2005-06-24
申请人： Joseph Bringley , John Harder , Thomas Penner , Tiecheng Qiao , Ruizheng Wang
发明人： Joseph Bringley , John Harder , Thomas Penner , Tiecheng Qiao , Ruizheng Wang
IPC分类号： B01J13/00 , B32B5/16
CPC分类号： A61K9/146 , A61K9/5146 , A61K49/0032 , A61K49/0043 , A61K49/0076 , A61K49/0093 , B01J13/04 , C03C12/00 , C03C17/32 , Y10T428/2991 , Y10T428/2993 , Y10T428/2998
摘要： There are disclosed colloids containing polymer-modified core-shell particle carrier. The described colloids containing core-shell nanoparticulate carrier particles wherein the shell contains a polymer having amine functionalities. The described carrier particles are stable under physiological conditions. The carriers can be bioconjugated with biological, pharmaceutical or diagnostic components.
摘要翻译：公开了含有聚合物改性的核 - 壳粒子载体的胶体。所述胶体含有核 - 壳纳米颗粒载体颗粒，其中壳包含具有胺官能团的聚合物。所描述的载体颗粒在生理条件下是稳定的。载体可以与生物，药物或诊断成分生物共轭。

2. 发明授权

US07406797B2 Super high floating line 有权
标题翻译：超高浮线
公开(公告)号：US07406797B2
公开(公告)日：2008-08-05
申请号：US11213588
申请日：2005-08-26
申请人： John Harder , Marlin Roush , John Schultz , Timothy Moon
发明人： John Harder , Marlin Roush , John Schultz , Timothy Moon
IPC分类号： A01K91/00 , D02G3/00
CPC分类号： A01K91/12 , Y10T428/2927 , Y10T428/2929 , Y10T428/2933 , Y10T428/2967 , Y10T428/2969
摘要： Fly fishing lines and methods for manufacturing fly fishing lines entail the use of polymer microspheres within the fly line coating to produce lines with very low specific gravities. The fly lines have single or multiple coatings. In fly lines having multiple coatings, the inner coating includes polymer microspheres and the outer coating include either polymer microspheres or glass microspheres.
摘要翻译：飞钓线和用于制造飞钓线的方法需要在飞线涂层中使用聚合物微球以产生具有非常低比重的线。飞线具有单层或多层涂层。在具有多个涂层的飞线中，内涂层包括聚合物微球，外涂层包括聚合物微球体或玻璃微球体。

3. 发明申请

US20050192381A1 Amine polymer-modified nanoparticulate carriers 失效
标题翻译：胺聚合物改性纳米颗粒载体
公开(公告)号：US20050192381A1
公开(公告)日：2005-09-01
申请号：US11036814
申请日：2005-01-14
申请人： Joseph Bringley , Tiecheng Qiao , John Harder , Andrew Wunder , James Hewitt
发明人： Joseph Bringley , Tiecheng Qiao , John Harder , Andrew Wunder , James Hewitt
IPC分类号： B01J13/00 , B01J13/02 , B01J13/04 , C08F2/00
CPC分类号： B01J13/02 , B01J13/0008 , B01J13/0086 , B01J13/04 , Y10T428/2998
摘要： There are disclosed colloids containing polymer-modified core-shell particle carrier. The described colloids containing core-shell nanoparticulate carrier particles wherein the shell contains a polymer having amine functionalities. The described carrier particles are stable under physiological conditions. The carriers can be bioconjugated with biological, pharmaceutical or diagnostic components
摘要翻译：公开了含有聚合物改性的核 - 壳粒子载体的胶体。所述胶体含有核 - 壳纳米颗粒载体颗粒，其中壳包含具有胺官能团的聚合物。所描述的载体颗粒在生理条件下是稳定的。载体可以与生物，药物或诊断成分生物共轭

4. 发明授权

US4655448A Exercise apparatus 失效
标题翻译：运动器材
公开(公告)号：US4655448A
公开(公告)日：1987-04-07
申请号：US740729
申请日：1985-06-03
申请人： John Harder
发明人： John Harder
IPC分类号： A63B21/068 , A63B21/00
CPC分类号： A63B21/068
摘要： An exercise device of the body supporting type includes a generally H-shaped frame with collapsible legs at each end thereof, so that the frame can be elevated at the foot or head end; a board or backrest pivotally connected to the head end of the frame and extending towards the foot end of the frame; handles extending outwardly from the free end of the backrest for grasping by the user when in the prone position; and footrests for anchoring the feet of a user to the foot end of the frame. By grasping the handles and pressing against the footrests, the user can rotate the backrest around the head end of the frame to an inclined position in which the user is standing on the footrests.
摘要翻译：身体支撑型的运动装置包括在其每个端部具有可折叠的腿的大致H形的框架，使得框架可以在脚部或头部端部被升高; 枢转地连接到框架的头端并朝向框架的脚端延伸的板或靠背; 手柄从靠背的自由端向外延伸，用于当处于俯卧位时由使用者握住; 以及用于将使用者的脚固定到框架的脚端的搁脚板。通过握住把手并按压脚踏板，用户可以将围绕框架的头端的靠背旋转到使用者站在搁脚板上的倾斜位置。

5. 发明授权

US07563485B2 Method of manufacturing a super high floating line 有权
标题翻译：制造超高浮线的方法
公开(公告)号：US07563485B2
公开(公告)日：2009-07-21
申请号：US11387621
申请日：2006-03-23
申请人： John Harder , Marlin Roush , John Schultz , Timothy Moon
发明人： John Harder , Marlin Roush , John Schultz , Timothy Moon
IPC分类号： B05D5/00 , B05D7/02 , B05D7/24 , A01K91/00
CPC分类号： A01K91/12 , Y10T428/2927 , Y10T428/2929 , Y10T428/2933 , Y10T428/2967 , Y10T428/2969
摘要： Methods of manufacturing fly fishing lines with very low specific gravities entail adding polymer microspheres to a base coating and coating a core with the base coating containing the added polymer microspheres. To manufacture fly lines having multiple coatings, a second coating, which may contain polymer or glass microspheres, is disposed around a first coating that contains polymer microspheres.
摘要翻译：制造具有非常低比重的飞钓线的方法需要将聚合物微球加入到基底涂层中，并用含有添加的聚合物微球体的基底涂层涂覆芯。为了制造具有多个涂层的飞线，可以包含聚合物或玻璃微球的第二涂层围绕包含聚合物微球的第一涂层设置。

6. 发明申请

US20070238656A1 Functionalized poly(ethylene glycol) 审中-公开
标题翻译：官能化聚（乙二醇）
公开(公告)号：US20070238656A1
公开(公告)日：2007-10-11
申请号：US11400935
申请日：2006-04-10
申请人： John Harder , Jeffrey Leon
发明人： John Harder , Jeffrey Leon
IPC分类号： A61K38/00
CPC分类号： C08G65/329 , C08G65/334 , C08G65/3344 , C08G65/3348
摘要： The present invention relates to a bi-functional compound containing a linking material, and a particle comprising a linking material, and a linking material comprising a polyethylene glycol macromonomer backbone with a radical polymerizable group at one end of the macromonomer backbone and a different reactive chemical functionality at the other end of the macromonomer backbone, according to Formula I: wherein X is CH3, CN or H; Y is O, NR1, or S; L is a linking group or spacer; FG is a functional group; n is greater than 4 and less than 1000; and wherein R1 and R2 are independently selected from substituted or unsubstituted alkyl, aryl, or heteroyl.
摘要翻译：本发明涉及包含连接材料的双功能化合物和包含连接材料的颗粒，以及包含在大分子单体骨架的一端具有自由基聚合性基团的聚乙二醇大分子单体骨架和不同的反应性化学物质的连接材料在大分子单体骨架的另一端的官能团，根据式I：其中X是CH 3，CN或H; Y是O，NR 1或S; L是连接基团或间隔基; FG是功能组; n大于4且小于1000; 并且其中R 1和R 2独立地选自取代或未取代的烷基，芳基或杂基。

7. 发明申请

US20070237821A1 Nanogel-based contrast agents for optical molecular imaging 审中-公开
标题翻译：基于Nanogel的光学分子成像造影剂
公开(公告)号：US20070237821A1
公开(公告)日：2007-10-11
申请号：US11401343
申请日：2006-04-10
申请人： Jeffrey Leon , James Bennett , Tiecheng Qiao , John Harder , Thomas Mourey , Gary Slater , Lijun Dai
发明人： Jeffrey Leon , James Bennett , Tiecheng Qiao , John Harder , Thomas Mourey , Gary Slater , Lijun Dai
IPC分类号： A61K9/14
CPC分类号： A61K49/0093 , A61K47/6903 , A61K47/6933 , A61K49/0032 , A61K49/0073 , B82Y5/00
摘要： The present invention relates to a nanogel comprising a polymer network of repetitive, crosslinked, ethylenically unsaturated monomers of Formula I: (X)m-(Y)n-(Z)o Formula I wherein X is a water-soluble monomer containing ionic or hydrogen bonding moieties; Y is a water-soluble macromonomer containing repetitive hydrophilic units bound to a polymerizeable ethylenically unsaturated group; Z is a multifunctional crosslinking monomer; m ranges from 50-90 mol %; n ranges from 2-30 mol %; and o range from 1-15 mol % and a method for preparing a nanogel comprising preparing a header composition of a mixture of monomers X, Y, and Z, and a first portion of initiators in water; preparing a reactor composition of a second portion initiators, surfactant, and water; bringing the reactor composition to the polymerization temperature; holding the reactor composition at the polymerization temperature, and adding the header composition to the reactor composition to form a nanogel of Formula I.
摘要翻译：本发明涉及纳米凝胶，其包含式I的重复，交联，烯键式不饱和单体的聚合物网络：<？在线公式描述=“在线式”末端=“铅”→（X）m- （Y）n-（Z）o式I <？in-line-formula description =“In-line Formulas”end =“tail”？>其中X是含有离子或氢键结构部分的水溶性单体; Y是含有与可聚合烯属不饱和基团结合的重复亲水单元的水溶性大分子单体; Z是多功能交联单体; m范围为50-90摩尔％; n范围为2-30mol％; 其范围为1-15mol％，制备纳米凝胶的方法包括制备单体X，Y和Z的混合物的头部组合物和在水中的第一部分引发剂; 制备第二部分引发剂，表面活性剂和水的反应器组合物; 使反应器组成达到聚合温度; 将反应器组合物保持在聚合温度，并将集管组合物加入到反应器组合物中以形成式I的纳米凝胶。

8. 发明申请

US20060172077A1 Method of manufacturing a super high floating line 有权
标题翻译：制造超高浮线的方法
公开(公告)号：US20060172077A1
公开(公告)日：2006-08-03
申请号：US11387621
申请日：2006-03-23
申请人： John Harder , Marlin Roush , John Schultz , Timothy Moon
发明人： John Harder , Marlin Roush , John Schultz , Timothy Moon
IPC分类号： B05D1/18
CPC分类号： A01K91/12 , Y10T428/2927 , Y10T428/2929 , Y10T428/2933 , Y10T428/2967 , Y10T428/2969
摘要： Fly fishing lines and methods for manufacturing fly fishing lines entail the use of polymer microspheres within the fly line coating to produce lines with very low specific gravities. The fly lines have single or multiple coatings. In fly lines having multiple coatings, the inner coating includes polymer microspheres and the outer coating include either polymer microspheres or glass microspheres.
摘要翻译：飞钓线和用于制造飞钓线的方法需要在飞线涂层中使用聚合物微球以产生具有非常低比重的线。飞线具有单层或多层涂层。在具有多个涂层的飞线中，内涂层包括聚合物微球，外涂层包括聚合物微球体或玻璃微球体。

9. 发明申请

US20060048440A1 Super high floating line and method of manufacturing same 有权
标题翻译：超高浮线和制造方法相同
公开(公告)号：US20060048440A1
公开(公告)日：2006-03-09
申请号：US11213588
申请日：2005-08-26
申请人： John Harder , Marlin Roush , John Schultz , Timothy Moon
发明人： John Harder , Marlin Roush , John Schultz , Timothy Moon
IPC分类号： A01K91/12
CPC分类号： A01K91/12 , Y10T428/2927 , Y10T428/2929 , Y10T428/2933 , Y10T428/2967 , Y10T428/2969
摘要： Fly fishing lines and methods for manufacturing fly fishing lines entail the use of polymer microspheres within the fly line coating to produce lines with very low specific gravities. The fly lines have single or multiple coatings. In fly lines having multiple coatings, the inner coating includes polymer microspheres and the outer coating include either polymer microspheres or glass microspheres.
摘要翻译：飞钓线和用于制造飞钓线的方法需要在飞线涂层中使用聚合物微球以产生具有非常低比重的线。飞线具有单层或多层涂层。在具有多个涂层的飞线中，内涂层包括聚合物微球，外涂层包括聚合物微球体或玻璃微球体。

10. 发明授权

US5831519A Traffic supervision system for vehicles 失效
标题翻译：车辆交通监管系统
公开(公告)号：US5831519A
公开(公告)日：1998-11-03
申请号：US836723
申请日：1997-07-21
申请人： Heine Ewi Pedersen , John Harder , Flemming Lohmann-Jensen
发明人： Heine Ewi Pedersen , John Harder , Flemming Lohmann-Jensen
IPC分类号： G08G1/017 , B61L25/02 , G08B25/10 , G08G1/127 , B60Q1/00
CPC分类号： G08G1/127 , B61L25/025 , B61L2205/04
摘要： A traffic supervision system for transport systems (17) of the type comprising a towing unit and one or more transporting or transported units, the towing unit having a data processing unit (1) with transmit and receive facilities adapted to read/write messages from stationarily located tags (10B) or to transmit information via a wireless transmission (7) in which the towed, transporting or transported unit or units have another data processing unit (15) having transmit and receive facilities capable of exchanging information with the data processing unit (1) in the towing unit via a wireless transmission (7) or via an interface (8).
摘要翻译： PCT No.PCT / DK95 / 00460 Sec。 371日期1997年7月21日 102（e）日期1997年7月21日PCT 1995年11月21日PCT PCT。 WO96 / 16387 PCT出版物日期1996年5月30日一种包括牵引单元和一个或多个运输或运输单元的运输系统（17）的交通监督系统，牵引单元具有数据处理单元（1），其具有适于读/ 从固定位置的标签（10B）写入消息或经由无线传输（7）发送信息，其中拖曳，传送或传送的单元或单元具有另一数据处理单元（15），该数据处理单元（15）具有能够与数据处理单元（1）经由无线传输（7）或经由接口（8）在拖曳单元中。

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