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    • 7. 发明授权
    • LV threshold measurement and capture management
    • LV阈值测量和捕获管理
    • US08744579B2
    • 2014-06-03
    • US12700454
    • 2010-02-04
    • Purvee P. ParikhJohn C. StroebelTodd J. SheldonKaren J. Kleckner
    • Purvee P. ParikhJohn C. StroebelTodd J. SheldonKaren J. Kleckner
    • A61N1/00
    • A61N1/3627A61N1/3684A61N1/371
    • The invention provides methods and apparatus for determining in a non-tracking pacing mode (e.g., DDI/R, VVI/R) whether a ventricular pacing stimulus is capturing a paced ventricle, including some or all of the following aspects. For example, increasing a ventricular pacing rate a nominal amount to an overdrive pacing rate higher than a most recent heart rate and evaluating a conduction interval from a first pacing ventricle to a second sensing ventricle and then continuing to monitor the underlying rate to ensure that a threshold testing pacing rate will not exceed a predetermined minimum interval and providing pacing stimulation to the first ventricle and sensing the second ventricle to determine whether the pacing stimulation to the first ventricle was one of sub-threshold and supra-threshold. The methods and apparatus are especially useful in conjunction with ensuring actual delivery of a ventricular pacing regime (e.g., cardiac resynchronization therapy or “CRT”).
    • 本发明提供了用于在非跟踪起搏模式(例如,DDI / R,VVI / R)中确定心室起搏刺激是否捕获节奏心室的方法和装置,包括以下方面中的一些或全部。 例如,将心室起搏速率提高到高于最近心率的超速起搏速率的标称值,并评估从第一起搏心室到第二感测心室的传导间隔,然后继续监测潜在速率,以确保 阈值测试起搏速率不会超过预定的最小间隔,并且向第一脑室提供起搏刺激并且感测第二脑室以确定对第一脑室的起搏刺激是否是子阈值和超阈值之一。 所述方法和装置与确保心室起搏方案(例如,心脏再同步治疗或“CRT”)的实际递送相结合特别有用。
    • 8. 发明授权
    • Method and apparatus for detecting cardiac capture
    • 用于检测心脏捕获的方法和装置
    • US5902325A
    • 1999-05-11
    • US126469
    • 1998-07-30
    • Catherine R. CondieDaniel J. BaxterWilliam J. CombsDaniel J. GreeningerKaren J. KlecknerH. Toby MarkowitzJohn C. StroebelJohn D. Wahlstrand
    • Catherine R. CondieDaniel J. BaxterWilliam J. CombsDaniel J. GreeningerKaren J. KlecknerH. Toby MarkowitzJohn C. StroebelJohn D. Wahlstrand
    • A61N1/365A61N1/37
    • A61N1/36521A61N1/3712A61N1/3714
    • A method and apparatus for automatic determination of a pacemaker patient's pacing stimulation threshold. Circuitry is provided in a pacemaker for obtaining a signal reflecting cardiac impedance, which is known to reliably reflect certain aspects of cardiac function. Circuitry is also provided for monitoring the cardiac impedance waveform during a predetermined capture detect window following delivery of stimulating pulses. One or more values are derived which characterize the morphology of the impedance waveform during the capture detect window associated with each stimulation pulse delivered. These values are compared to predetermined control values in order to assess whether a stimulation pulse has achieved cardiac capture. The assessment of whether cardiac capture has been achieved is also based partly upon the conventional sensing of atrial and/or ventricular cardiac signals occurring during the capture detect window. In one embodiment of the invention, the control values against which impedance waveform characterization values are compared are obtained by delivering a series of stimulation pulses having sufficient energy to ensure that capture is achieved, and by monitoring the impedance waveform during delivery of these pulses.
    • 一种用于自动确定起搏器患者起搏刺激阈值的方法和装置。 在起搏器中提供电路以获得反映心脏阻抗的信号,这已知可靠地反映心脏功能的某些方面。 还提供电路用于在传送刺激脉冲之后的预定捕获检测窗口期间监测心脏阻抗波形。 导出一个或多个值,其表征在与递送的每个刺激脉冲相关联的捕获检测窗口期间阻抗波形的形态。 将这些值与预定的控制值进行比较,以便评估刺激脉冲是否已经实现心脏捕获。 是否已经实现心脏捕获的评估也部分地基于在捕获检测窗口期间发生的心房和/或心室心脏信号的常规感测。 在本发明的一个实施例中,通过递送具有足够能量的一系列刺激脉冲来确定阻抗波形表征值被比较的控制值,以确保实现捕获,并且通过在传送这些脉冲期间监视阻抗波形来获得。
    • 10. 发明申请
    • LV THRESHOLD MEASUREMENT AND CAPTURE MANAGEMENT
    • LV阈值测量和捕获管理
    • US20100137935A1
    • 2010-06-03
    • US12700454
    • 2010-02-04
    • Purvee P. ParikhJohn C. StroebelTodd J. SheldonKaren J. Kleckner
    • Purvee P. ParikhJohn C. StroebelTodd J. SheldonKaren J. Kleckner
    • A61N1/08A61N1/362
    • A61N1/3627A61N1/3684A61N1/371
    • The invention provides methods and apparatus for determining in a non-tracking pacing mode (e.g., DDI/R, VVI/R) whether a ventricular pacing stimulus is capturing a paced ventricle, including some or all of the following aspects. For example, increasing a ventricular pacing rate a nominal amount to an overdrive pacing rate higher than a most recent heart rate and evaluating a conduction interval from a first pacing ventricle to a second sensing ventricle and then continuing to monitor the underlying rate to ensure that a threshold testing pacing rate will not exceed a predetermined minimum interval and providing pacing stimulation to the first ventricle and sensing the second ventricle to determine whether the pacing stimulation to the first ventricle was one of sub-threshold and supra-threshold. The methods and apparatus are especially useful in conjunction with ensuring actual delivery of a ventricular pacing regime (e.g., cardiac resynchronization therapy or “CRT”).
    • 本发明提供了用于在非跟踪起搏模式(例如,DDI / R,VVI / R)中确定心室起搏刺激是否捕获节奏心室的方法和装置,包括以下方面中的一些或全部。 例如,将心室起搏速率提高到高于最近心率的超速起搏速率的标称值,并评估从第一起搏心室到第二感测心室的传导间隔,然后继续监测潜在速率,以确保 阈值测试起搏速率不会超过预定的最小间隔,并且向第一脑室提供起搏刺激并且感测第二脑室以确定对第一脑室的起搏刺激是否是子阈值和超阈值之一。 所述方法和装置与确保心室起搏方案(例如,心脏再同步治疗或“CRT”)的实际递送相结合特别有用。