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1. 发明授权

US06701188B2 Controlling noise sources during telemetry 有权
标题翻译：在遥测中控制噪声源
公开(公告)号：US06701188B2
公开(公告)日：2004-03-02
申请号：US09947691
申请日：2001-09-06
申请人： John C. Stroebel , Forrest C. M. Pape , Paul J. Huelskamp , David J. Peichel , Chris T. House , James H. Ericksen
发明人： John C. Stroebel , Forrest C. M. Pape , Paul J. Huelskamp , David J. Peichel , Chris T. House , James H. Ericksen
IPC分类号： A61N1362
CPC分类号： A61N1/3975 , A61N1/3718 , A61N1/3956 , A61N1/3981
摘要： The invention presents techniques for reducing the interference to telemetry from an implanted medical device caused by a source of controllable noise. In the context of an implanted system that includes a defibrillator system and a telemetry system, for example, the invention reduces the interference by suspending energy storage during telemetry. The invention further provides for suspending energy storage operation gradually rather than abruptly, by gradually reducing the duty cycle of a clock that controls the energy storage.
摘要翻译：本发明提出了用于减少由可控噪声源引起的植入式医疗装置对遥测的干扰的技术。在包括除颤器系统和遥测系统的植入系统的上下文中，例如，本发明通过在遥测期间暂停能量存储来减少干扰。本发明还通过逐渐降低控制能量存储的时钟的占空比来进一步提供暂停而不是突然地暂停能量存储操作。

2. 发明授权

US06754527B2 System and method for reducing noise in an implantable medical device 有权
标题翻译：用于减少植入式医疗装置中的噪声的系统和方法
公开(公告)号：US06754527B2
公开(公告)日：2004-06-22
申请号：US09948069
申请日：2001-09-06
申请人： John C. Stroebel , Forrest C. M. Pape , Paul J. Huelskamp
发明人： John C. Stroebel , Forrest C. M. Pape , Paul J. Huelskamp
IPC分类号： A61N139
CPC分类号： A61N1/3975 , A61N1/3718 , A61N1/3981 , Y10S128/901
摘要： A system and method for reducing the amount of noise causes by inductive elements within an implantable medical device. In particular, the invention provides a system for gradually initiating and terminating the current flow within inductive elements such as transformers that are used to charge energy storage devices such as high-voltage capacitors of an implantable cardio/defibrillator. This more gradual change in the rate of current flow prevents ground shifts and subsequent noise spikes within the device. This, in turn, allows cardiac signals to be sensed more accurately by sensing circuits, preventing oversensing, and minimizing the occurrence of inappropriate shock delivery.
摘要翻译：用于减少由可植入医疗装置内的感应元件引起的噪音量的系统和方法。特别地，本发明提供一种用于逐渐启动和终止电流元件（例如变压器）内的电流的系统，所述变压器用于对诸如可植入的心/除颤器的高压电容器等能量存储装置进行充电。电流流动速率的这种逐渐变化可防止器件内的接地位移和随后的噪声尖峰。这反过来又允许通过感测电路更精确地感测心脏信号，防止过度感染，并且使不适当的电击递送的发生最小化。

3. 发明授权

US06959214B2 Implantable medical device for measuring mechanical heart function 失效
标题翻译：用于测量机械心脏功能的植入式医疗设备
公开(公告)号：US06959214B2
公开(公告)日：2005-10-25
申请号：US09996138
申请日：2001-11-28
申请人： Forrest C. M. Pape , Paul J. Huelskamp
发明人： Forrest C. M. Pape , Paul J. Huelskamp
IPC分类号： A61N1/362 , A61N1/365
CPC分类号： A61N1/36514 , A61N1/3627
摘要： An implantable device for measuring mechanical heart function of selected heart chambers using a heart contraction detection system that includes a magnetic field sensor. The system may be used for monitoring signs of acute or chronic cardiac heart failure, to enable diagnosis of the condition of the heart, to prescribe appropriate therapies, and to assess delivered pacing therapies. Distance measurements within the heart are made using the magnetic field sensor which is implanted at a sensor site in or on one of the right or left ventricle. A magnet implanted at a site relative to the other of the left or right heart ventricle is sufficiently spaced at a distance that fluctuates with expansion and contraction of the ventricles. The magnetic field sensor provides a sensor output signal having a signal magnitude proportional to the magnetic field strength of the magnet, and which is indicative of changing cardiac dimensions.
摘要翻译：一种用于使用包括磁场传感器的心脏收缩检测系统来测量所选择的心室的机械心脏功能的可植入装置。该系统可以用于监测急性或慢性心脏衰竭的迹象，以便能够诊断心脏的状况，开出适当的治疗方法，以及评估发放的起搏疗法。心脏内的距离测量使用植入在右心室或左心室中的一个传感器位置的磁场传感器来进行。植入在相对于左心室或右心室另一个的位置处的磁体在与心室的扩张和收缩波动的距离处充分间隔开。磁场传感器提供具有与磁体的磁场强度成比例的信号幅度的传感器输出信号，并且其指示改变心脏尺寸。

4. 发明授权

US06721592B2 Automatic electrogram measurement 有权
标题翻译：自动电描记测量
公开(公告)号：US06721592B2
公开(公告)日：2004-04-13
申请号：US09952717
申请日：2001-09-12
申请人： David Peichel , Tho Huynh , Forrest C. M. Pape , Robert A. Neumann , John C. Stroebel , Robert A. Gabler , James E. Willenbring
发明人： David Peichel , Tho Huynh , Forrest C. M. Pape , Robert A. Neumann , John C. Stroebel , Robert A. Gabler , James E. Willenbring
IPC分类号： A61B50452
CPC分类号： A61B5/0456 , A61N1/3704
摘要： Techniques for monitoring the magnitudes of representative filtered EGM signals over time. In a typical implementation, a group of digital peak values is generated in a time period and a representative digital peak value is selected for the time period. By comparing representative peak values for several time periods, changes in signal efficacy can be identified.
摘要翻译：用于随时间监视代表性滤波EGM信号幅度的技术。在典型的实现中，在一段时间内产生一组数字峰值，并在该时间段内选择代表性的数字峰值。通过比较几个时间段的代表性峰值，可以确定信号功效的变化。

5. 发明授权

US08050763B2 Isolation circuitry and method for gradient field safety in an implantable medical device 有权
标题翻译：可植入式医疗设备中梯度场安全的隔离电路和方法
公开(公告)号：US08050763B2
公开(公告)日：2011-11-01
申请号：US12759228
申请日：2010-04-13
申请人： Lonny V. Cabelka , David E. Manahan , Forrest C. M. Pape , John D. Wahlstrand
发明人： Lonny V. Cabelka , David E. Manahan , Forrest C. M. Pape , John D. Wahlstrand
IPC分类号： A61N1/372
CPC分类号： A61N1/3752 , A61N1/3718
摘要： An implantable medical device is provided for isolating an elongated medical lead from internal device circuitry in the presence of a gradient magnetic or electrical field. The device includes an isolation circuit adapted to operatively connect an internal circuit to the medical lead in a first operative state and to electrically isolate the medical lead from the internal circuit in a second operative state.
摘要翻译：提供了可植入医疗装置，用于在梯度磁场或电场的存在下将细长的医疗引线与内部装置电路隔离。该装置包括隔离电路，其适于在第一操作状态下将内部电路可操作地连接到医疗引线，并且在第二操作状态下将医疗引线与内部电路电隔离。

6. 发明授权

US6141583A Implantable medical device incorporating performance based adjustable power supply 有权
标题翻译：可植入医疗器械，采用基于性能的可调电源
公开(公告)号：US6141583A
公开(公告)日：2000-10-31
申请号：US247458
申请日：1999-02-09
申请人： Forrest C. M. Pape , Carl A. Schu
发明人： Forrest C. M. Pape , Carl A. Schu
IPC分类号： A61N1/08 , A61N1/378
CPC分类号： A61N1/378 , A61N1/08
摘要： A method or apparatus for conserving power in an implantable medical device (IMD) of the type having at least one IC powered by a battery wherein, in each such IC, a voltage dependent oscillator for providing oscillator output signals at an oscillation frequency dependent upon applied supply voltage to the IC is incorporated into the IC. The voltage dependent oscillator oscillates at a frequency that is characteristic of the switching speed of all logic circuitry on the IC die that can be attained with the applied supply voltage. The applied supply voltage is regulated so that the oscillation frequency is maintained at no less than a target or desired oscillation frequency or within a desired oscillation frequency range. The power supply voltage that is applied to the IC is based directly on the performance of all logic circuitry of the IC. In order to provide the comparison function, the oscillator output signals are counted, and the oscillator output signal count accumulated over a predetermined number of system clock signals is compared to a target count that is correlated to the desired oscillation frequency. The counts are compared, and the supply voltage is adjusted upward or downward or is maintained the same dependent upon whether the oscillator output signal count falls below or rises above or is equal to the target count, respectively. The supply voltage adjustment is preferably achieved employing a digitally controlled power supply by calculating a digital voltage from the comparison of the oscillator output signal count to the target count, and storing the digital voltage in a register of the power supply.
摘要翻译：一种用于在具有由电池供电的至少一个IC的类型的可植入医疗装置（IMD）中节省电力的方法或装置，其中在每个这样的IC中，具有电压的振荡器，用于以取决于应用的振荡频率提供振荡器输出信号将IC的电源电压并入IC。电压相关振荡器以可以通过施加的电源电压获得的IC芯片上所有逻辑电路的开关速度特性的频率振荡。所施加的电源电压被调节，使得振荡频率保持在不小于目标或期望的振荡频率或在期望的振荡频率范围内。施加到IC的电源电压基于IC的所有逻辑电路的性能。为了提供比较功能，对振荡器输出信号进行计数，并将累积在预定数量的系统时钟信号上的振荡器输出信号计数与与期望的振荡频率相关的目标计数进行比较。比较计数，并且电源电压被向上或向下调整或保持相同，这取决于振荡器输出信号计数是否分别低于或等于目标计数。优选地，通过从振荡器输出信号计数与目标计数的比较计算数字电压，并将数字电压存储在电源的寄存器中，通过使用数字控制的电源来实现电源电压调节。

7. 发明授权

US07729770B2 Isolation circuitry and method for gradient field safety in an implantable medical device 失效
标题翻译：可植入式医疗设备中梯度场安全的隔离电路和方法
公开(公告)号：US07729770B2
公开(公告)日：2010-06-01
申请号：US11380241
申请日：2006-04-26
申请人： Lonny V. Cabelka , David E. Manahan , Forrest C. M. Pape , John D. Wahlstrand
发明人： Lonny V. Cabelka , David E. Manahan , Forrest C. M. Pape , John D. Wahlstrand
IPC分类号： A61N1/372
CPC分类号： A61N1/3752 , A61N1/3718
摘要： An implantable medical device is provided for isolating an elongated medical lead from internal device circuitry in the presence of a gradient magnetic or electrical field. The device includes an isolation circuit adapted to operatively connect an internal circuit to the medical lead in a first operative state and to electrically isolate the medical lead from the internal circuit in a second operative state.
摘要翻译：提供了可植入医疗装置，用于在梯度磁场或电场的存在下将细长的医疗引线与内部装置电路隔离。该装置包括隔离电路，其适于在第一操作状态下将内部电路可操作地连接到医疗引线，并且在第二操作状态下将医疗引线与内部电路电隔离。

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