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    • 48. 发明申请
    • METHOD AND DEVICE FOR VASCULAR THERAPY
    • 用于血管治疗的方法和装置
    • US20120232636A1
    • 2012-09-13
    • US13476292
    • 2012-05-21
    • Ram H. Paul, Jr.
    • Ram H. Paul, Jr.
    • A61F2/82A61F2/84
    • A61M29/02A61M2025/0024A61M2025/0096A61M2025/0188
    • Medical devices, as well as methods of treatment and manufacturing such devices, are provided for applying vascular therapy locally within the body vessel. The medical devices include an expandable tubular frame and a sleeve. The medical devices can be used for local delivery of a therapeutic agent within a body vessel or a tamponade for a lacerated body vessel, while simultaneously allowing perfusion of fluid or blood flow distal of the implanted medical device. The tubular frame of the medical device can have a middle region with a plurality of members. The members can expand radially outward away from a longitudinal axis of the tubular frame, which can urge the sleeve to contact the wall of the body vessel. In the expanded configuration, a portion of the device allows fluid flow to continue while the sleeve is against the body vessel wall.
    • 提供医疗装置以及治疗和制造这种装置的方法,用于在体内血管局部施用血管治疗。 医疗装置包括可扩张的管状框架和套筒。 医疗装置可用于局部递送用于撕裂体血管的体内容器或填塞物中的治疗剂,同时允许灌注植入的医疗装置的远端的流体或血液流。 医疗装置的管状框架可以具有带有多个构件的中间区域。 构件可以从管状框架的纵向轴线径向向外膨胀,这可以促使套筒接触身体容器的壁。 在扩展构型中,当套管抵靠身体血管壁时,该装置的一部分允许流体流动继续。
    • 50. 发明申请
    • VESSEL CLOSURE DEVICE
    • 船舶关闭装置
    • US20120179172A1
    • 2012-07-12
    • US13497708
    • 2010-09-20
    • Ram H. Paul, JR.Brian L. BatesCleon Stanley
    • Ram H. Paul, JR.Brian L. BatesCleon Stanley
    • A61B17/128A61B17/122
    • A61B17/0057A61B17/29A61B2017/0034A61B2017/00473A61B2017/00575A61B2017/2905A61B2017/2931A61B2017/303
    • A device and system for closure of an opening formed in a body vessel includes a bioabsorbable grasping member and locking member. The grasping member includes grasping lingers that are radially collapsible to the closed positions by movement of the locking member over the fingers. A distal portion of the fingers is configured to grasp an outer wall portion of the body vessel surrounding the opening when the fingers are in the open position. Movement of the locking member can cause the fingers to at least substantially close the vessel opening. Structural features on the fingers and/or locking member can inhibit proximal or distal movement of the locking member when in a locking position. A detachable arm can be coupled to the grasping member to facilitate placement of the grasping member. A sheath can fit over the detachable arm and be configured to move the locking member over the fingers.
    • 用于封闭形成在体容器中的开口的装置和系统包括生物可吸收的抓持构件和锁定构件。 抓持构件包括通过锁定构件通过手指的移动而径向可折叠到关闭位置的抓握件。 手指的远端部分构造成当手指处于打开位置时抓住围绕开口的身体血管的外壁部分。 锁定构件的运动可导致手指至少基本上关闭容器开口。 手指和/或锁定构件上的结构特征可以在锁定位置时阻止锁定构件的近端或远端运动。 可拆卸臂可以联接到抓握构件以便于抓握构件的放置。 护套可以装配在可拆卸臂上方并且被配置成使锁定构件移动超过手指。