专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

31. 发明授权

US06686195B1 Method and apparatus for ultrasonic lysis of biological cells 失效
标题翻译：生物细胞超声裂解的方法和装置
公开(公告)号：US06686195B1
公开(公告)日：2004-02-03
申请号：US09937992
申请日：2001-12-13
申请人： Bruno Colin , Philippe Cleuziat , Patrick Broyer , Claude Mabilat , Sandra Incardona
发明人： Bruno Colin , Philippe Cleuziat , Patrick Broyer , Claude Mabilat , Sandra Incardona
IPC分类号： C12M133
CPC分类号： B01J19/10 , B06B3/00 , C12M45/02
摘要： An apparatus including at least one sonotrode (2) designed to generate ultrasound of variable power in at least one biological sample (5) containing cells to be lysed, the sample (5) being contained in at least one receptacle (4 or 10) such that the sonotrode (2) is in direct contact with the receptacle(s) (4). Also disclosed is a method for using ultrasound to lyse a biological sample (5) contained in a receptacle (4), which includes placing the receptacle (4) in direct contact with the sonotrode (2), and activating the sonotrode (2) for long enough to lyse the cells in the sample (5) but preserve the DNA and/or RNA molecules released for subsequent operations, e.g. amplification. The invention is particularly applicable in the discipline of molecular biology.
摘要翻译：一种装置，包括至少一个超声波发生器（2），其被设计成在至少一个含有待裂解细胞的生物样品（5）中产生可变功率的超声波，所述样品（5）包含在至少一个容器（4或10）中，超声波发生器（2）与容器（4）直接接触。还公开了一种使用超声波来溶解包含在容器（4）中的生物样品（5）的方法，其包括将容器（4）放置在与超声焊极（2）直接接触的位置，并且激活超声焊极（2）以用于足以裂解样品（5）中的细胞，但保留释放用于后续操作的DNA和/或RNA分子，例如放大。本发明特别适用于分子生物学学科。

32. 发明授权

US06641545B1 Biological sampling method 有权
标题翻译：生物抽样方法
公开(公告)号：US06641545B1
公开(公告)日：2003-11-04
申请号：US09675648
申请日：2000-09-29
申请人： Bruno Colin , Cécile Jaravel , Marie Privat
发明人： Bruno Colin , Cécile Jaravel , Marie Privat
IPC分类号： A61B1000
CPC分类号： G01N35/1016 , G01N2035/1025 , Y10T436/2575
摘要： A method for drawing a biological sample using a suction-discharge device, such as a manual or automatic pipette, built into an automated device or not. A method for detecting the free surface of a biological sample and/or solid, a sample drawing device such as a pipette and a device for detecting the free surface of a biological sample or a solid are also disclosed. This method includes actuating a means causing a pressure variation or an air flow within the suction-discharge device, positioning the lower free end of the device in such a way so that it becomes flush with a free surface of the biological sample, measuring an overpressure within the suction-discharge device, and sampling a quantity of the sample by suction using the device. The invention finds a preferable application in the field of automatic analyzers.
摘要翻译：使用内置于自动化装置中的吸引 - 排出装置（例如手动或自动移液管）来绘制生物样品的方法。还公开了用于检测生物样品和/或固体的自由表面的方法，诸如移液管的样品拉伸装置和用于检测生物样品或固体的游离表面的装置。该方法包括致动一个在吸入 - 排出装置内产生压力变化或空气流动的装置，以这样的方式定位装置的下部自由端，使其与生物样品的自由表面齐平，测量过压并且使用该装置通过抽吸对一定量的样品进行采样。本发明在自动分析仪领域中发现了优选的应用。

33. 发明授权

US5951952A Test sample card 失效
公开(公告)号：US5951952A
公开(公告)日：1999-09-14
申请号：US872813
申请日：1997-06-11
申请人： Raymond E. O'Bear , Bruno Colin , G. R. Tegeler , John L. Staples
发明人： Raymond E. O'Bear , Bruno Colin , G. R. Tegeler , John L. Staples
IPC分类号： G01N33/52 , B01L3/00 , B29C45/00 , G01N1/28 , G01N21/03 , G01N35/00 , G01N35/02 , C12Q1/02
CPC分类号： B01L3/502715 , B01L3/502 , B01L3/5025 , B01L3/502723 , B29C45/0025 , B01L2200/025 , B01L2200/0684 , B01L2200/0689 , B01L2300/0816 , B01L2300/0864 , B01L2400/049 , G01N2035/00148 , Y10T436/111666 , Y10T436/112499 , Y10T436/113332
摘要： An improved sample card is provided. The improved card, typically used in biochemical analysis, achieves high sample well capacity and improved fluid flow, including by means of a plurality of through-channels which route the fluid flow of samples along both the front and back surfaces of the card. Elevated bubble traps are provided, as are integral interrupt slots for sensing card position and alignment. A bezeled leading edge facilitates insertion.

34. 发明授权

US5932177A Test sample card 失效
公开(公告)号：US5932177A
公开(公告)日：1999-08-03
申请号：US872812
申请日：1997-06-11
申请人： Raymond E. O'Bear , Bruno Colin , G. R. Tegeler , John L. Staples
发明人： Raymond E. O'Bear , Bruno Colin , G. R. Tegeler , John L. Staples
IPC分类号： G01N33/52 , B01L3/00 , B29C45/00 , G01N1/28 , G01N21/03 , G01N35/00 , G01N35/02 , C12M1/18
CPC分类号： B01L3/502715 , B01L3/502 , B01L3/5025 , B01L3/502723 , B29C45/0025 , B01L2200/025 , B01L2200/0684 , B01L2200/0689 , B01L2300/0816 , B01L2300/0864 , B01L2400/049 , G01N2035/00148 , Y10T436/111666 , Y10T436/112499 , Y10T436/113332
摘要： An improved sample card is provided. The improved card, typically used in biochemical analysis, achieves high sample well capacity and improved fluid flow, including by means of a plurality of through-channels which route the fluid flow of samples along both the front and back surfaces of the card. Elevated bubble traps are provided, as are integral interrupt slots for sensing card position and alignment. A bezeled leading edge facilitates insertion.

35. 发明授权

US11092600B2 Method for the real-time detection of microorganisms in a liquid culture medium by agglutination 有权
公开(公告)号：US11092600B2
公开(公告)日：2021-08-17
申请号：US12918159
申请日：2009-03-12
申请人： Bruno Colin , David Mosticone , Jean-Claude Raymond , Thierry Sofia , Antoine Vimont
发明人： Bruno Colin , David Mosticone , Jean-Claude Raymond , Thierry Sofia , Antoine Vimont
IPC分类号： G01N33/569 , C12Q1/04 , G01N33/53
摘要： A method for detecting at least one microorganism that may be present in a sample, comprising the steps of: a) bringing into contact, in a container: a culture medium that enables the growth and/or detection of microorganisms, said sample and a sensitized solid support; b) subjecting the whole to a temperature that promotes the growth and/or detection of microorganisms; and c) observing, in real time, the appearance of an agglutination indicating the presence of the microorganism(s) or confirming said presence when said microorganisms are detected in said culture medium, when step b) has been completed, and a method for detecting and identifying at least one target microorganism that may be present in a sample.

36. 发明授权

US09353398B2 Method for isolating a sample well of a test card for analysis, and resulting test card 有权
标题翻译：用于分离测试卡的样品阱以分析的方法，以及所得到的测试卡
公开(公告)号：US09353398B2
公开(公告)日：2016-05-31
申请号：US13879887
申请日：2011-10-19
申请人： Bruno Colin , Cécile Paris
发明人： Bruno Colin , Cécile Paris
IPC分类号： C12Q1/24 , B01L3/00
CPC分类号： B01L3/50853 , B01L3/502738 , B01L2200/0689 , B01L2300/0864 , B01L2300/0887 , B01L2400/0481 , B01L2400/0638 , B01L2400/0655 , C12Q1/24
摘要： The invention relates to a method for isolating at least one fluid sample well laid out in a test card for analysis, said test card including a plate (3) having at least one first main face from which is laid out at least one channel communicating with at least said well, this first face being coated with a membrane (17) provided with an adhesive (18) and which will cover said channel with a covering area (171), the method for isolation including a phase for introducing a fluid sample into at least said well and a phase for isolating said well consisting of exerting a force on at least one portion of the covering area (171) of the adhesive membrane (17) for ensuring displacement of the adhesive into an obturation area for the sample well.
摘要翻译：本发明涉及一种隔离在测试卡中布置的至少一个流体样本的方法，用于分析，所述测试卡包括板（3），板（3）具有至少一个第一主面，布置有至少一个与至少所述井，该第一面涂覆有具有粘合剂（18）的膜（17），并且其将覆盖所述通道并具有覆盖区域（171），所述隔离方法包括用于将流体样品引入的相至少所述井以及用于隔离所述井的相，其包括在所述粘合膜（17）的覆盖区域（171）的至少一部分上施加力，以确保所述粘合剂移动到所述样品井的封闭区域。

37. 发明授权

US09085792B2 Methods for inoculating culture media on Petri dishes by means of vibration frequencies 有权
标题翻译：通过振动频率将培养基接种在培养皿上的方法
公开(公告)号：US09085792B2
公开(公告)日：2015-07-21
申请号：US14238673
申请日：2012-08-30
申请人： Bruno Colin , Marie-Pierre Montet
发明人： Bruno Colin , Marie-Pierre Montet
IPC分类号： C12Q1/24 , C12M1/22 , C12M1/00 , C12M1/26
CPC分类号： C12Q1/24 , C12M23/10 , C12M23/38 , C12M33/08
摘要： The present invention relates to a method for inoculating at least one agar culture medium, contained in a Petri dish, with at least one sample likely to contain microorganisms. The method includes the steps of: providing at least one agar culture medium contained in a Petri dish; providing the sample likely to contain microorganisms in liquid form; performing at least one deposition of the liquid sample onto the lid of the Petri dish such that the liquid sample can be transferred from the lid to the agar culture medium; and spraying the liquid sample, initially deposited onto the cover, onto the agar culture medium by vibrating the Petri dish.
摘要翻译：本发明涉及用至少一种可能含有微生物的样品接种培养皿中含有的至少一种琼脂培养基的方法。该方法包括以下步骤：提供培养皿中所含的至少一种琼脂培养基; 提供样品可能含有液体形式的微生物; 将液体样品的至少一次沉积物执行到培养皿的盖上，使得液体样品可以从盖子转移到琼脂培养基中; 并通过振动培养皿将初始沉积到盖上的液体样品喷洒到琼脂培养基上。

38. 发明申请

US20140093428A1 DEVICE AND METHOD FOR IMMUNOASSAYS 审中-公开
标题翻译：用于免疫功能的装置和方法
公开(公告)号：US20140093428A1
公开(公告)日：2014-04-03
申请号：US14123145
申请日：2012-06-04
申请人： Hélène Briand , Bruno Colin , Cécile Paris
发明人： Hélène Briand , Bruno Colin , Cécile Paris
IPC分类号： G01N33/53 , B29C43/46
CPC分类号： G01N33/5302 , B29C43/46 , G01N33/54386 , G01N33/558 , G01N33/56988
摘要： The present invention relates to a device for performing an immunoassay, the device including a) a support, b) a porous matrix, fixed on the support, the matrix including (i) a liquid sample application area, (ii) a labeling area and (iii) at least one reaction area which includes a test results display area and a verification area, said liquid sample application area labeling area and reaction area being in fluid communication; the device including, at the verification area, at least a part of the porous matrix has pores with dimensions smaller than those of the labeled particles, such that at least a proportion of the labeled particles from the labeling area is stopped at said verification area forming a symbol which is visible or displayable for a user; and a method for manufacturing the device.
摘要翻译：本发明涉及一种用于进行免疫测定的装置，该装置包括a）支撑体，b）固定在载体上的多孔基质，所述基质包括（i）液体样品施用区域，（ii）标记区域和（iii）至少一个包括测试结果显示区域和验证区域的反应区域，所述液体样品应用区域标记区域和反应区域处于流体连通状态; 所述装置包括在验证区域处的多孔基质的至少一部分具有尺寸小于被标记颗粒尺寸的孔，使得至少一部分来自标记区域的标记颗粒在所述验证区域形成对用户可见或可显示的符号; 以及该装置的制造方法。

39. 发明申请

US20130011566A1 Petri Dish Comprising Means for Holding Agar Culture Medium 审中-公开
标题翻译：培养皿包含琼脂培养培养基的培养皿
公开(公告)号：US20130011566A1
公开(公告)日：2013-01-10
申请号：US13636196
申请日：2011-03-24
申请人： Bruno Colin , Nathalie Simon
发明人： Bruno Colin , Nathalie Simon
IPC分类号： C12M1/22 , B05D3/00
CPC分类号： C12M23/10 , B01L3/508 , B01L2300/0851
摘要： The present invention relates to a Petri dish, intended for receiving an agar culture medium for microorganisms, including a base receiving said culture medium and a lid capable of being positioned on the base, said base and said lid being substantially circular, said Petri dish being characterised in that the base includes at least one means intended to avoid the retraction of the culture medium, said means projecting and being positioned on the periphery of the base.
摘要翻译：本发明涉及一种用于接收微生物的琼脂培养基的培养皿，包括接收所述培养基的基底和能够定位在基底上的盖，所述基部和所述盖基本上是圆形的，所述培养皿是其特征在于，所述底座包括用于避免所述培养基回缩的至少一个装置，所述装置突出并定位在所述基部的周边上。

40. 发明申请

US20130004287A1 Holder for Culture Plates with De-Nesting Feature 审中-公开
标题翻译：具有脱巢功能的文化馆持有人
公开(公告)号：US20130004287A1
公开(公告)日：2013-01-03
申请号：US13609382
申请日：2012-09-11
申请人： Bruno Colin , Yaneli lakimova , Kevin G. Ketsenberg , David M. Robbins , Stéphane Bellet
发明人： Bruno Colin , Yaneli lakimova , Kevin G. Ketsenberg , David M. Robbins , Stéphane Bellet
IPC分类号： B65G59/06 , B65G61/00
CPC分类号： C12M23/48 , C12M23/10 , G01N35/04 , G01N2035/042 , G01N2035/0425
摘要： A holding structure for holding a plurality of culture plates in a stacked arrangement includes a feature for de-nesting the bottom culture plate from the plate above it. The de-nesting feature is preferably a structure which urges a plate to move laterally relative to the plate above it. The de-nesting of the bottom culture plate from the adjacent culture plate facilitates withdrawal of the bottom culture plate from the base via a robotic plate transfer mechanism. The de-nesting feature can be entirely passive, such as ramps formed in the base of the holding structure.
摘要翻译：用于保持多个培养板的堆叠布置的保持结构包括用于将底部培养板从其上方的板上嵌套的特征。去嵌套特征优选地是一种促使板相对于其上方的板横向移动的结构。来自相邻培养板的底部培养板的解嵌有助于通过机器人板转移机构将底部培养板从基底中取出。去嵌套特征可以是完全无源的，例如形成在保持结构的基部中的斜面。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式