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    • 7. 发明申请
    • Integrated Analysis Device Which Can Be Fitted To A Container Housing A Sample To Be Analyzed
    • 综合分析装置可以适用于集装箱住房要分析的样本
    • US20080152541A1
    • 2008-06-26
    • US11597867
    • 2005-06-24
    • David MosticonePascal MontesJean-Claude RaymondBruno ColinCecile Paris
    • David MosticonePascal MontesJean-Claude RaymondBruno ColinCecile Paris
    • G01N30/00B01J19/00G01N35/10
    • B01L3/505B01L2300/044B01L2300/0663B01L2300/0672B01L2300/0825B01L2400/0406Y10T436/110833Y10T436/112499
    • The present invention relates generally to the field of analysis, for example biological analysis. More specifically, the present invention relates to an analysis device (10, 40, 501, 60) designed to be associated with a container (22, 50, 70) containing a sample (28) to be analyzed, said device comprising essentially: a first impervious membrane (12, 42, 52, 62); a second impervious membrane (14, 44, 54, 64) superposed on the first membrane (12, 42, 52, 62); said first and second membranes being fixedly attached over at least a part of their surface, defining a peripheral zone, in order to define an interstitial space forming an internal reaction cavity (16, 46, 56, 66), with no means of fluid communication with the outside of said analysis device (10, 40, 501, 60); at least one analysis means (18, 47, 57, 67), placed inside said internal reaction cavity (16, 46, 56, 66), designed to be placed in contact with the sample (28); at least one means designed to create a way for the sample to enter said internal reaction cavity. The present invention also relates to a container (22, 50, 70) comprising such an analysis device.The present invention also relates to a method of analyzing a sample contained in a container, in which an analysis device according to the invention is used.
    • 本发明一般涉及分析领域,例如生物分析。 更具体地说,本发明涉及一种设计成与容纳待分析样品(28)的容器(22,50,70)相关联的分析装置(10,40,501,60),所述装置基本上包括: 第一不透水膜(12,42,52,62); 叠置在第一膜(12,42,52,62)上的第二不透水膜(14,44,54,64); 所述第一和第二膜固定地附接在其表面的至少一部分上,限定了周边区域,以便限定形成内部反应腔(16,46,56,66)的间隙空间,没有任何流体连通 与所述分析装置的外部(10,40,501,60); 放置在与所述样品(28)接触的所述内部反应腔(16,46,56,66)内的至少一个分析装置(18,47,57,67); 至少一种设计用于创建样品进入所述内部反应腔的方式的装置。 本发明还涉及包括这种分析装置的容器(22,50,70)。 本发明还涉及一种分析包含在容器中的样品的方法,其中使用了根据本发明的分析装置。
    • 8. 发明授权
    • Integrated analysis device which can be fitted to a container housing a sample to be analyzed
    • 集成分析装置,其可以装配到容纳待分析样品的容器中
    • US08518342B2
    • 2013-08-27
    • US11597867
    • 2005-06-24
    • David MosticonePascal MontesJean-Claude RaymondBruno ColinCecile Paris
    • David MosticonePascal MontesJean-Claude RaymondBruno ColinCecile Paris
    • G01N21/75
    • B01L3/505B01L2300/044B01L2300/0663B01L2300/0672B01L2300/0825B01L2400/0406Y10T436/110833Y10T436/112499
    • The present invention relates generally to the field of analysis, for example biological analysis. More specifically, the present invention relates to an analysis device (10, 40, 501, 60) designed to be associated with a container (22, 50, 70) containing a sample (28) to be analyzed, said device comprising essentially: a first impervious membrane (12, 42, 52, 62); a second impervious membrane (14, 44, 54, 64) superposed on the first membrane (12, 42, 52, 62); said first and second membranes being fixedly attached over at least a part of their surface, defining a peripheral zone, in order to define an interstitial space forming an internal reaction cavity (16, 46, 56, 66), with no means of fluid communication with the outside of said analysis device (10, 40, 501, 60); at least one analysis means (18, 47, 57, 67), placed inside said internal reaction cavity (16, 46, 56, 66), designed to be placed in contact with the sample (28); at least one means designed to create a way for the sample to enter said internal reaction cavity. The present invention also relates to a container (22, 50, 70) comprising such an analysis device.The present invention also relates to a method of analyzing a sample contained in a container, in which an analysis device according to the invention is used.
    • 本发明一般涉及分析领域,例如生物分析。 更具体地说,本发明涉及一种设计成与容纳待分析样品(28)的容器(22,50,70)相关联的分析装置(10,40,501,60),所述装置基本上包括: 第一不透水膜(12,42,52,62); 叠置在第一膜(12,42,52,62)上的第二不透水膜(14,44,54,64); 所述第一和第二膜固定地附接在其表面的至少一部分上,限定了周边区域,以便限定形成内部反应腔(16,46,56,66)的间隙空间,没有任何流体连通 与所述分析装置的外部(10,40,501,60); 放置在与所述样品(28)接触的所述内部反应腔(16,46,56,66)内的至少一个分析装置(18,47,57,67); 至少一种设计用于创建样品进入所述内部反应腔的方式的装置。 本发明还涉及包括这种分析装置的容器(22,50,70)。 本发明还涉及一种分析包含在容器中的样品的方法,其中使用了根据本发明的分析装置。
    • 9. 发明授权
    • Method for identifying bacteria from the Bacillus cereus group
    • 从蜡样芽胞杆菌群鉴定细菌的方法
    • US08871465B2
    • 2014-10-28
    • US13496422
    • 2010-09-16
    • Marie CellierJohn MillsDavid MosticoneSylvain OrengaAntoine Vimont
    • Marie CellierJohn MillsDavid MosticoneSylvain OrengaAntoine Vimont
    • C12Q1/04
    • C12Q1/04C12Q1/44
    • The present invention relates to a method for identifying bacteria of the Bacillus cereus group, comprising the following steps: (a) providing a sample that may contain bacteria of the Bacillus cereus group, a reaction medium comprising at least one fluorescent phosphatidylcholine phospholipase C (PC-PLC) substrate and an inhibitor of Gram-negative bacteria; (b) inoculating the reaction medium with the sample; (c) incubating the inoculated reaction medium; and (d) identifying the bacteria of the Bacillus cereus group by detecting the PC-PLC substrate hydrolysis reaction, in which the pH of the reaction medium and the time necessary for detecting the PC-PLC substrate hydrolysis reaction are adapted such that said hydrolysis reaction by bacteria of the Bacillus cereus group is detected before hydrolysis of the PC-PLC substrate by any Gram-positive bacteria other than those belonging to the Bacillus cereus group, that may be present in the sample.
    • 本发明涉及一种用于鉴定蜡状芽孢杆菌群体细菌的方法,包括以下步骤:(a)提供可含有蜡样芽孢杆菌群细菌的样品,包含至少一种荧光磷脂酰胆碱磷脂酶C(PC -PLC)底物和革兰氏阴性菌的抑制剂; (b)用样品接种反应介质; (c)孵育接种的反应介质; 和(d)通过检测PC-PLC底物水解反应来鉴定蜡状芽孢杆菌群的细菌,其中反应介质的pH和检测PC-PLC底物水解反应所需的时间适应于所述水解反应 在可能存在于样品中的除了属于蜡状芽孢杆菌属的那些之外的任何革兰氏阳性细菌在PC-PLC底物水解之前检测到蜡状芽孢杆菌的细菌。