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    • 22. 发明授权
    • Tert-alkylphenoxy-substituted polycyclic compounds
    • 叔烷基苯氧基取代的多环化合物
    • US07145010B2
    • 2006-12-05
    • US10472546
    • 2002-03-20
    • Arno BoehmWilli HelferGeorg BeckMatthias KriegerPeter Erk
    • Arno BoehmWilli HelferGeorg BeckMatthias KriegerPeter Erk
    • C07D221/18D06P1/00
    • C07D241/38C07D209/56C07D211/08C07D471/06C07D487/06C08K5/0041C09B3/44C09B5/62C09B47/18C09B69/00C09D5/36C09D11/037
    • Tert-alkylphenoxy-substituted polycyclic compounds of the general formula I where P is a conjugated polycyclic radical which is stable to bases and nucleophiles, optionally bears aryl substituents and contains no group from the group consisting of —CO—NH—CO—, —COOH and —CO—O—CO—; R is C1–C8-alkyl, whose carbon chain may be interrupted by one or more groups selected from the group consisting of —O—, —S—, —NR1—, —CO— and/or —SO2— and which may be monosubstituted or polysubstituted by C1–C6-alkoxy or by a 5- to 7-membered heterocyclic radical which is attached via a nitrogen atom and may contain further heteroatoms and be aromatic; C5–C8-cycloalkyl whose carbon chain may be interrupted by one or more groups selected from the group consisting of —O—, —S—, —NR1—, —CO— and/or —SO2— and which may be monosubstituted or polysubstituted by C1–C6-alkyl; R1 is hydrogen or C1–C6-alkyl; Hal is chlorine and/or bromine; m is from 0 to 15; n is from 1 to 16, subject to the proviso that the sum m+n is ≦16, are prepared and used.
    • 通式I的叔烷基苯氧基取代的多环化合物,其中P是对碱和亲核试剂稳定的共轭多环基团,任选地带有芳基取代基,并且不包含-CO-NH-CO-,-COOH 和-CO-O-CO-; R是C 1 -C 8 - 烷基,其碳链可以被一个或多个选自-O - , - S - , - NR 1 - , - CO - 和/或-SO 2 - ,并且其可以被C 1 -C 1单取代或多取代, 6 - 烷氧基或通过氮原子连接并可以含有其它杂原子并且为芳族的5-至7-元杂环基; C 5 -C 8 -C 8 - 环烷基,其碳链可被一个或多个选自-O - , - S - , - NR < -CO - 和/或-SO 2 - ,并且其可以被C 1 -C 6单取代或多取代, 亚烷基; R 1是氢或C 1 -C 6 - 烷基; Hal是氯和/或溴; m为0〜15; n为1至16,但条件是m + n之和<= 16,并被使用。