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1. 发明公开

EP2620476A4 PIGMENT AND COLORED PHOTOSENSITIVE COMPOSITION 审中-公开
标题翻译：颜料和彩色感光组合物
公开(公告)号：EP2620476A4
公开(公告)日：2016-11-16
申请号：EP11826732
申请日：2011-09-08
申请人： ADEKA CORP
发明人： MAEDA YOSUKE , SHIMIZU MASAAKI , MATSUHIRA KEISUKE
IPC分类号： C09B23/00 , C09B11/02 , C09B11/06 , C09B23/01 , C09B23/10 , C09B23/14 , C09B57/00 , C09B67/20 , G02B5/20 , G02B5/22 , G02F1/1335 , G11B7/246
CPC分类号： C09B57/008 , B33Y70/00 , C09B11/02 , C09B11/06 , C09B23/0058 , C09B23/105 , C09B23/14 , C09B23/143 , G02B5/223 , G02F1/133514 , G02F2202/04 , G11B7/246

2. 发明公开

EP1553408A4 FLUORESCENT PROBE 审中-公开
标题翻译： FLUORESZENZSONDE
公开(公告)号：EP1553408A4
公开(公告)日：2005-08-17
申请号：EP03741232
申请日：2003-07-07
申请人： NAGANO TETSUO , DAIICHI PURE CHEMICALS CO LTD
发明人： NAGANO TETSUO , URANO YASUTERU , KENMOKU SUGURU , KANDA KOHJIRO
IPC分类号： C07D311/82 , C07D407/04 , C09B11/06 , C09B11/24 , G01N27/447 , G01N31/22 , G01N31/00 , G01N21/78
CPC分类号： G01N27/44726 , C07D311/82 , C09B11/06 , C09B11/245 , G01N31/22
摘要： A fluorescent probe represented by the following formula (I): (I) wherein R1 and R2 each represents hydrogen, a substituent for trapping a proton, metal ion, or active oxygen species, etc.; R3 represents a monovalent substituent; R4 and R5 each represents hydrogen or halogeno; and R6 represents hydrogen, alkylcarbonyl, or alkylcarbonyloxymethyl; provided that R1, R2, and R3 are selected in such a combination that (1) before the trapping of, e.g., a proton, R1, R2, and R3 give a substantially high electron density to the benzene ring to which they are bonded, in order that the compound represented by the formula (I) be substantially nonfluorescent and that (2) after the trapping of, e.g., a proton, R1, R2, and R3 substantially reduce the electron density of the benzene ring to which they are bonded, in order that the compound resulting from the trapping and derived from the compound represented by the formula (I) be substantially highly fluorescent. The fluorescent probe has excellent fluorescent properties.
摘要翻译：由下式（I）表示的荧光探针：（I）其中R 1和R 2各自表示氢，用于俘获质子的取代基，金属离子或活性氧等; R3代表一价取代基; R4和R5各自代表氢或卤代; 和R6代表氢，烷基羰基或烷基羰氧基甲基; 条件是R1，R2和R3以如下组合选择：（1）在俘获例如质子之前，R1，R2和R3给与它们键合的苯环提供相当高的电子密度，为了使式（I）表示的化合物基本上无荧光，并且（2）在捕获例如质子之后，R 1，R 2和R 3实质上降低它们键合的苯环的电子密度以便由捕获得到的和由式（I）代表的化合物衍生的化合物基本上是高度荧光的。荧光探针具有优异的荧光特性。

3. 发明公开

EP3050886A1 Fluorescent dyes and dye precursors 审中-公开
标题翻译： Fluoreszenzfarbstoffe undFarbstoffvorläufer
公开(公告)号：EP3050886A1
公开(公告)日：2016-08-03
申请号：EP15153463.3
申请日：2015-02-02
申请人： Bürkert Werke GmbH
发明人： Lelant, Célia , Bonnet, Dominique , Galzi, Jean-Luc
IPC分类号： C07D493/10 , A61K31/35 , A61K31/365 , C09B11/06 , C09K11/06 , C09K11/59 , C09K11/66 , C12N1/00 , C12Q1/02 , G01N33/48 , G01N33/50 , G01N21/64 , G01N33/52
CPC分类号： C07D493/10 , C09B11/06 , C09B11/08 , C09K11/06 , C12Q1/02 , G01N1/30 , G01N33/48 , G01N33/50 , G01N33/5091 , G01N33/582
摘要： A xanthene compound is used for discriminating living from non-living unicellular and multicellular organisms. The xanthene compound is represented by the following formula (I)

wherein
each X is, independently from each other, one of H, F, Cl, Br, I, CN;
Z is one of O, Si, Ge or Sn;
R 1 is hydrogen, -(C=O)-R 4 or -CH 2 -O-(C=O)-R 4 , wherein R 4 is substituted or unsubstituted alkyl having 1 to 18 carbon atoms, substituted or unsubstituted alkenyl having 2 to 18 carbon atoms, or substituted or unsubstituted aralkyl having at least 7 carbon atoms, or wherein R 1 is a residue derived from an amino acid, peptide, nucleotide or oligonucleotide, monosaccaride or polysaccharide;
A is -NH 2 , -OR 1 or -NR 5 (C=O)-R 4 wherein R 4 independently has the meaning as defined above and R 5 is H, substituted or unsubstituted alkyl having 1 to 18 carbon atoms, substituted or unsubstituted alkenyl having 2 to 18 carbon atoms, or substituted or unsubstituted aralkyl having at least 7 carbon atoms;
R 2 and R 3 are, independently from each other, H or -(C=O)-NR 6 R 7 , wherein at least one of R 2 and R 3 is not H, and wherein R 6 and R 7 are selected from H, substituted or unsubstituted alkyl having 1 to 18 carbon atoms, substituted or unsubstituted alkenyl having 2 to 18 carbon atoms, or substituted or unsubstituted aralkyl having at least 7 carbon atoms.
摘要翻译：呫吨化合物用于区分生活与非生物单细胞和多细胞生物的生物。呫吨化合物由下式（I）表示，其中每个X彼此独立地为H，F，Cl，Br，I，CN之一; Z是O，Si，Ge或Sn之一; R 1是氢， - （C = O）-R 4或-CH 2 -O-（C = O）-R 4，其中R 4是具有1至18个碳原子的取代或未取代的烷基， 2至18个碳原子，或取代或未取代的具有至少7个碳原子的芳烷基，或其中R 1是衍生自氨基酸，肽，核苷酸或寡核苷酸，单糖或多糖的残基; A是-NH 2，-OR 1或-NR 5（C = O）-R 4，其中R 4独立地具有如上定义的含义，R 5是H，取代或未取代的具有1至18个碳原子的烷基，取代或具有2至18个碳原子的未取代的烯基，或具有至少7个碳原子的取代或未取代的芳烷基; R 2和R 3彼此独立地为H或 - （C = O）-NR 6 R 7，其中R 2和R 3中的至少一个不是H，并且其中R 6和R 7选自 H，取代或未取代的碳原子数1〜18的烷基，取代或未取代的碳原子数为2〜18的烯基或取代或未取代的碳数7以上的芳烷基。

4. 发明公开

EP2768306A4 FLUORESCENT DYES 有权
标题翻译： FLUORESZENZFARBSTOFFE
公开(公告)号：EP2768306A4
公开(公告)日：2015-06-24
申请号：EP12839327
申请日：2012-10-09
申请人： ENZO LIFE SCIENCES INC
发明人： LI ZAIGUO , PANDE PRAVEEN
IPC分类号： C07D311/88 , C09B11/24 , C12Q1/70
CPC分类号： C07H21/00 , C07H19/04 , C09B11/02 , C09B11/06 , C09B11/24 , C12Q1/707
摘要： Provided are various compounds comprising the formula Also provided are fluorescent dyes comprising the above compound. Additionally, a fluorescence energy transfer system is provided that comprises the above-described fluorescent dye and a second dye, wherein the second dye is capable of energy transfer with the fluorescent dye. Further provided is a kit for labeling a target molecule, where the kit comprises the above-described fluorescent dye with additional reagents useful for labeling the target molecule. Additionally provided is a target molecule labeled with the above-described fluorescent dye. Methods of labeling a target molecule with the above-described fluorescent dye are also provided.
摘要翻译：提供包含式的各种化合物还提供了包含上述化合物的荧光染料。此外，提供了包含上述荧光染料和第二染料的荧光能量转移系统，其中第二染料能够与荧光染料进行能量转移。还提供了用于标记靶分子的试剂盒，其中试剂盒包含上述荧光染料和另外的可用于标记靶分子的试剂。另外提供了用上述荧光染料标记的靶分子。还提供了用上述荧光染料标记靶分子的方法。

5. 发明公开

EP0553346A1 PHOTOGRAPHIC PRODUCTS AND PROCESSES 失效
标题翻译：摄影产品和程序。
公开(公告)号：EP0553346A1
公开(公告)日：1993-08-04
申请号：EP92919934.0
申请日：1992-08-19
申请人： POLAROID CORPORATION
发明人： JANDRUE, Charles, E., Sr. , KAMPE, Marcis, M. , SIMON, Myron, S. , WALLER, David, P. , WHRITENOUR, David, C.
IPC分类号： B32B7 , C07D307 , C07D311 , C07D333 , C09B11 , G03C8
CPC分类号： G03C8/48 , C07D307/94 , C07D311/96 , C09B11/06 , C09B11/24
摘要： On décrit une nouvelle catégorie de colorants indicateurs pontés présentant une absorption dans la zone infrarouge du spectre électromagnétique. Ces colorants indicateurs pontés sont utiles comme agents de filtrage optique sensibles au pH et absorbant la lumière dans des procédés photographiques de transfert par diffusion conçus pour être exécutés à la lumière ambiante, ainsi que dans des produits de transfert par diffusion convenant à ces procédés. Les colorants indicateurs peuvent également être utilisés pour effectuer des titrages et dans d'autres techniques d'analyse, ainsi que dans des produits où des colorants indicateurs sensibles au pH sont utilisés, et où l'absorption d'infrarouge est requise.

6. 发明公开

EP2814803A1 TRISUBSTITUTED METHYL ALCOHOLS AND THEIR POLYMERIZABLE DERIVATIVES 审中-公开
标题翻译：三取代甲醇及其衍生物的聚合
公开(公告)号：EP2814803A1
公开(公告)日：2014-12-24
申请号：EP12856663.5
申请日：2012-12-14
申请人： Indicator Systems International, Inc.
发明人： SWISS, Gerald F. , RAO, Photon , SABNIS, Ram W.
IPC分类号： C07C43/20 , C07C41/34 , C07C41/58
CPC分类号： C07C43/23 , C07C69/54 , C07C69/738 , C07C265/08 , C07C331/24 , C09B11/06 , C09B69/103
摘要： Provided herein are trisubstituted methyl alcohols, preferably pH indicators that are substituted with optionally substituted aryl and or optionally substituted heteroaryl groups, and optionally include one or more polymerizable substituents.

7. 发明公开

EP2768306A1 FLUORESCENT DYES 有权
标题翻译：荧光探针
公开(公告)号：EP2768306A1
公开(公告)日：2014-08-27
申请号：EP12839327.9
申请日：2012-10-09
申请人： Enzo Life Sciences, Inc., c/o Enzo Biochem, Inc.
发明人： LI, Zaiguo , PANDE, Praveen
IPC分类号： A01N43/16 , A61K31/35 , C07D311/88
CPC分类号： C07H21/00 , C07H19/04 , C09B11/02 , C09B11/06 , C09B11/24 , C12Q1/707
摘要： Provided are various compounds comprising the formula Also provided are fluorescent dyes comprising the above compound. Additionally, a fluorescence energy transfer system is provided that comprises the above-described fluorescent dye and a second dye, wherein the second dye is capable of energy transfer with the fluorescent dye. Further provided is a kit for labeling a target molecule, where the kit comprises the above-described fluorescent dye with additional reagents useful for labeling the target molecule. Additionally provided is a target molecule labeled with the above-described fluorescent dye. Methods of labeling a target molecule with the above-described fluorescent dye are also provided.

8. 发明公开

EP2620476A1 PIGMENT AND COLORED PHOTOSENSITIVE COMPOSITION 审中-公开
标题翻译： GIFÄRBTELICHTEMPFINDLICHE ZUSAMMENSETZUNG的颜料
公开(公告)号：EP2620476A1
公开(公告)日：2013-07-31
申请号：EP11826732.7
申请日：2011-09-08
申请人： Adeka Corporation
发明人： MAEDA, Yosuke , SHIMIZU, Masaaki , MATSUHIRA, Keisuke
IPC分类号： C09B23/00 , C09B67/20 , G02B5/20 , G02B5/22 , G02F1/1335
CPC分类号： C09B57/008 , B33Y70/00 , C09B11/02 , C09B11/06 , C09B23/0058 , C09B23/105 , C09B23/14 , C09B23/143 , G02B5/223 , G02F1/133514 , G02F2202/04 , G11B7/246
摘要： The present invention provides a dye that is excellent in solubility and excellent in heat resistance and a novel compound that is preferable for the dye, and specifically provides a yellow dye having a wavelength of maximum absorption in the region of 400 to 450 nm, and also provides a coloring (alkali-developable) photosensitive composition using the above-mentioned dye, and an optical filter using the above-mentioned coloring (alkali-developable) photosensitive composition, specifically a color filter that does not decrease luminance and thus is preferable for image display devices such as liquid crystal display panels. Specifically, a compound represented by the following general formula (1) is used as the dye. The content of the above-mentioned general formula (1) is as described in the description.
摘要翻译：本发明提供溶解性优异，耐热性优异的染料，对染料优选的新化合物，特别是在400〜450nm范围内提供最大吸收波长的黄色染料，提供使用上述染料的着色（碱显影性）感光性组合物和使用上述着色（碱显影性）感光性组合物的滤光器，特别是不降低亮度的滤色器，因此优选用于图像显示装置如液晶显示面板。具体地，使用由以下通式（1）表示的化合物作为染料。上述通式（1）的含量如说明书所述。

9. 发明公开

EP1553408A1 FLUORESCENT PROBE 审中-公开
标题翻译： FLUORESZENZSONDE
公开(公告)号：EP1553408A1
公开(公告)日：2005-07-13
申请号：EP03741232.7
申请日：2003-07-07
申请人： Nagano, Tetsuo , DAIICHI PURE CHEMICALS CO., LTD.
发明人： NAGANO, Tetsuo , URANO, Yasuteru , KENMOKU, Suguru , KANDA, Kohjiro
IPC分类号： G01N31/00 , G01N21/78
CPC分类号： G01N27/44726 , C07D311/82 , C09B11/06 , C09B11/245 , G01N31/22
摘要： A fluorescent probe which is represented by the following formula (I):
(wherein, R 1 and R 2 represent hydrogen atom, or a substituent for trapping proton, a metal ion, or an active oxygen species, or the like; R 3 represents a monovalent substituent; R 4 and R 5 represent hydrogen atom or a halogen atom; R 6 represents hydrogen atom, an alkylcarbonyl group, or an alkylcarbonyloxymethyl group, provided that a combination of R 1 , R 2 , and R 3 provides (1)substantially high electron density of the benzene ring to which said groups bind, so that the compound represented by the formula (I) is substantially no fluorescent before the trapping of proton, or the like, and (2) substantially reduced electron density of the benzene ring to which said groups bind, so that a compound after the trapping, which is derived from the compound represented by the formula (I) is substantially highly fluorescent after the trapping of proton or the like). A fluorescent probe having an excellent fluorescence property is provided.
摘要翻译：由下式（I）表示的荧光探针：（其中，R 1和R 2表示氢原子，或用于捕获质子，金属离子或活性氧的取代基， R 3表示一价取代基; R 4和R 5表示氢原子或卤素原子; R 6表示氢原子，烷基羰基或烷基羰氧基甲基，条件是a R 1，R 2和R 3的组合提供了（1）所述基团结合的苯环的基本上高的电子密度，使得由式（I）表示的化合物基本上不是荧光在质子捕获之前等等，以及（2）所述基团所结合的苯环的电子密度大大降低，从而得到由式（I）表示的化合物衍生的捕获后的化合物为在捕获质子等之后基本上高度荧光）。提供具有优异荧光特性的荧光探针。

10. 发明公开

EP0519198A2 Immobilization of PH-sensitive dyes to solid supports 失效
标题翻译： Immobilisierung von pH-empfindlichen Farbstoffen a festenTrägern。
公开(公告)号：EP0519198A2
公开(公告)日：1992-12-23
申请号：EP92107900.0
申请日：1992-05-11
申请人： Hewlett-Packard Company
发明人： Robotti, Karla M. , Myerholtz, Carl A.
IPC分类号： C09B11/04 , G01N21/80 , G01N33/52 , C09B11/06 , C09B11/08 , C09B11/22 , C09B11/24 , G01N31/22
CPC分类号： C07D307/885 , C07D307/92 , C07D327/04 , C09B11/06 , G01N31/221
摘要： Disclosed are pH dyes containing a suitable compatible substituent which permits binding of the dye to a solid support. Also disclosed are methods for synthesizing such dyes prior to their coupling to the solid supports.
摘要翻译：公开了含有合适的相容取代基的pH染料，其允许染料与固体支持物结合。还公开了在与固体支持物偶联之前合成这些染料的方法。

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