专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明公开

EP4443159A1 MEANS AND METHODS FOR DIAGNOSING A VIRAL INFECTION 审中-公开
公开(公告)号：EP4443159A1
公开(公告)日：2024-10-09
申请号：EP23166965.6
申请日：2023-04-06
申请人： Bruker BioSpin GmbH & Co. KG , Murdoch University
发明人： Wist, Julien , Sala, Samuele , Nitschke, Philipp , Nicholson, Jeremy J. , Holmes, Elaine , Trautwein, Christoph , Cannet, Claire
IPC分类号： G01N33/50 , C07F9/6558 , C07F9/6561 , G01N33/569 , G01N33/68
CPC分类号： G01N33/6848 , G01N33/5091 , G01N33/56983 , G01N2333/16520130101 , C07H19/06
摘要： The invention relates to the field of viral diagnosis. In particular, it is directed to a method for diagnosing a viral infection or a disease associated therewith in a subject comprising the steps of: (a) determining in a sample of said subject the amount of at least one biomarker selected from the group of 3'(,5'-di)deoxy-3',4'-didehydro furanose derivatives of formula (I) with the exception of 3'-deoxy-3',4'-didehydro-cytidine (ddhC); and (b) comparing the amount(s) of the at least one biomarkers determined in (a) with a reference, thereby diagnosing a viral infection.
Further, the invention is directed to a method for diagnosing a viral infection or a disease associated therewith in a subject comprising the steps of: (A) determining in a sample of said subject the amount of 3'-deoxy-3',4'-didehydro-cytidine (ddhC); and (B) comparing the amount of the ddhC determined in (A) with a reference, thereby diagnosing a viral infection;
wherein the determination in (a) is done by NMR spectroscopy and the sample of the subject is a urine sample of said subject.
The invention is also related to a diagnostic means for use in diagnosing a viral infection or a disease associated therewith, said diagnostic means comprising at least one biomarker selected from the group of 3'(,5'-di)deoxy-3',4'-didehydro furanose derivatives of formula (I) with the exception of 3'-deoxy-3',4'-didehydro-cytidine (ddhC), but also to a diagnostic means comprising 3'-deoxy-3',4'-didehydro-cytidine (ddhC) for use in diagnosing a viral infection or a disease associated therewith, wherein the amount of the biomarker is determined done by NMR spectroscopy in a urine sample of a subject.
Furthermore, the invention is directed to a device for diagnosing a viral infection or a disease associated therewith in a sample of a subject and to a kit for identifying a subject suffering from a viral infection or a disease associated therewith.

2. 发明授权

EP3262410B1 ASSAY TO DIAGNOSE AND TREAT DISORDERS OF THE ALTERNATIVE PATHWAY OF COMPLEMENT ACTIVATION 有权
公开(公告)号：EP3262410B1
公开(公告)日：2024-08-14
申请号：EP16756542.3
申请日：2016-02-29
IPC分类号： G01N33/50 , C12Q1/02 , A61K39/395 , A61P37/00
CPC分类号： C07K16/18 , C07K2317/2420130101 , C07K2317/7620130101 , G01N2440/0020130101 , G01N2800/2220130101 , G01N33/5091 , A61P7/00 , Y02A50/30

3. 发明公开

EP4392775A1 CANCER SCREENING IN COMPANION ANIMALS 审中-实审
公开(公告)号：EP4392775A1
公开(公告)日：2024-07-03
申请号：EP22862018.3
申请日：2022-08-24
申请人： Oncotect, Inc.
发明人： NAMGONG, Chan
IPC分类号： G01N33/48 , G01N33/487 , G01N30/72
CPC分类号： G01N33/5085 , G01N2333/4353420130101 , G01N33/5091 , G01N33/57407 , G01N33/5743 , G16H50/20 , G16H50/30 , G16H50/70 , G16H10/40 , G16H40/67 , G16H15/00 , G16H30/20 , G16H30/40

4. 发明公开

EP4388315A1 IMMUNE REPERTOIRE BIOMARKERS FOR PREDICTION OF TREATMENT RESPONSE IN AUTOIMMUNE DISEASE 审中-实审
公开(公告)号：EP4388315A1
公开(公告)日：2024-06-26
申请号：EP22790590.8
申请日：2022-08-17
申请人： Life Technologies Corporation
发明人： SARDA, Shrutii , LOWMAN, Geoffrey
IPC分类号： G01N33/50 , G01N33/68 , C12Q1/6881 , C12Q1/6883
CPC分类号： G01N33/5052 , G01N33/5091 , G01N33/6854 , C12Q2600/10620130101 , C12Q1/6883 , C12Q2600/15620130101

5. 发明公开

EP4370921A1 COMPOSITIONS AND METHODS FOR IMPROVING TREATMENT OF CANCER 审中-实审
公开(公告)号：EP4370921A1
公开(公告)日：2024-05-22
申请号：EP22842956.9
申请日：2022-07-15
申请人： Cypre, Inc.
发明人： HRIBAR, Kolin , XUE, Bin
IPC分类号： G01N33/50 , C12N5/078 , C12N5/077
CPC分类号： G01N33/5091 , G01N33/5082 , G01N2800/702820130101 , C12N2533/9020130101 , C12N2502/132320130101 , C12N5/0693 , C12N2513/0020130101 , A61P35/00 , A61K39/4615 , A61K39/4611 , A61K39/4614 , A61K39/4612 , A61K39/4622 , A61K39/4613 , A61K39/4644

6. 发明公开

EP4354139A1 NON-INVASIVE METHOD OF CELL IMAGING 审中-公开
公开(公告)号：EP4354139A1
公开(公告)日：2024-04-17
申请号：EP22382976.3
申请日：2022-10-13
申请人： Fundación Carlos Simón para la Investigación en Salud de la Mujer , The Trustees of the University of Pennsylvania
发明人： PLACHTA, Nicolas , SIMÓN, Carlos , BISSIERE, Stephanie
IPC分类号： G01N33/50 , G01N33/533 , G01N33/58 , C12Q1/6841
CPC分类号： C12Q1/6841 , G01N33/5091 , G01N33/582 , G01N2333/471220130101 , G01N33/689
摘要： The present invention relates to a method for obtaining one or more fluorescent images of one or more cells, the method comprising the steps of incubating the one or more cells with a first probe for fluorescence imaging of nuclear DNA and with a second probe for fluorescence imaging of actin and visualizing of the one or more cells stained with both probes by fluorescence microscopy. The method is particularly useful for monitoring embryo development and for diagnosing aneuploidy.

7. 发明授权

EP1920071B1 NEOPLASTIC DISEASE-RELATED METHODS, KITS, SYSTEMS AND DATABASES 有权
公开(公告)号：EP1920071B1
公开(公告)日：2018-12-26
申请号：EP06813244.8
申请日：2006-07-28
申请人： Siemens Healthcare Diagnostics Inc.
发明人： WIRTZ, Ralph, M. , AVERDICK, Manuela , BRÜCKL, Wolfgang , WEIN, Axel , THIEL, Robert, P.
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6886 , C12Q2600/106 , C12Q2600/118 , G01N33/5091 , G01N33/574 , G01N2800/52
摘要： In one embodiment, the invention provides methods for predicting a clinical outcome of a patient's neoplastic disease comprising: (a) determining a predictor value algorithmically using patient sample values for (1) at least one tumor marker or at least one immune marker, and (2) at least one marker that is (i) an extracellular matrix (ECM) marker (ii) a marker that is indicative of extracellular matrix synthesis (fibrogenesis), or (iii) a marker that is indicative of extracellular matrix degradation (fibrolysis); and (b) predicting the clinical outcome of the neoplastic disease by evaluating the predictor value.

8. 发明授权

EP3098602B1 DISTINCTION OF INFECTIOUS VIRUS BASED ON MOLECULAR BIOMARKER AND NEUTRALIZATION OF VIRUS CAUSING FOOD POISONING 有权
公开(公告)号：EP3098602B1
公开(公告)日：2018-10-31
申请号：EP16170158.6
申请日：2016-05-18
申请人： Industry Foundation of Chonnam National University , Korea Basic Science Institute
发明人： KIM, Du Woon , KWON, Joseph
IPC分类号： A61K38/16 , C12Q1/68 , G01N33/569 , G01N33/50
CPC分类号： G01N33/5088 , A61K38/168 , C12Q1/68 , G01N33/5091 , G01N33/56983 , G01N2333/08 , G01N2333/4603 , Y02A50/463
摘要： Discloses are a method for detecting Norovirus using a Norovirus animal model, a method for screening an antivial agent against Norovirus, and a composition for neutralizing the infection with an enteric virus, conaining concanavalin A as an active ingredient, so that the method for detecting Norovirus can allow the distinction between infectious Norovius and non-infectious Norovirus, and the composition can neutralize a virus causing food poisioning.

9. 发明授权

EP2972214B1 SHEATH FLUID SYSTEMS AND METHODS FOR PARTICLE ANALYSIS IN BLOOD SAMPLES 有权转让
公开(公告)号：EP2972214B1
公开(公告)日：2018-10-31
申请号：EP14723592.3
申请日：2014-03-17
申请人： Iris International, Inc.
发明人： FARRELL, Gregory, A. , WANDERS, Bart J. , ADAMS, Thomas H. , GRONER, Warren , ZHAO, Xiaodong
IPC分类号： G01N15/10 , G01N1/30 , G01N33/49 , G01N21/53 , G01N33/50 , G01N33/80 , G01N21/05 , G01N15/00 , G01N15/14
CPC分类号： G01N15/1404 , G01N1/30 , G01N15/1434 , G01N15/1463 , G01N15/1468 , G01N15/147 , G01N15/1475 , G01N21/53 , G01N33/49 , G01N33/4915 , G01N33/5091 , G01N33/5094 , G01N33/80 , G01N2015/0065 , G01N2015/1037 , G01N2015/1411 , G01N2015/1413 , G01N2015/1452 , G01N2015/1486 , G01N2021/058
摘要： The present disclosure relates to a staining methodology employing a particle contrast agent composition capable of rapidly staining cells in a single step. The particle contrast agent composition can be comprised of a combination of one or more particle contrast agents, one or more permeabilizing agents, and one or more fixing agents. The particle contrast agent composition can include Crystal Violet, New Methylene Blue, Saponin, and Gluteraldehyde.

10. 发明授权

EP2880440B1 GENDER, VIABILITY AND/OR DEVELOPMENTAL STAGE DETERMINATION OF AVIAN EMBRYOS IN OVO 有权转让
公开(公告)号：EP2880440B1
公开(公告)日：2018-10-31
申请号：EP13747889.7
申请日：2013-07-30
申请人： In Ovo B.V.
发明人： BRUINS, Wouter Sebastiaan , STUTTERHEIM, Wil Marijn
IPC分类号： G01N33/50 , G01N33/68
CPC分类号： G01N33/4833 , C12N7/00 , G01N33/50 , G01N33/5091 , G01N33/6812 , G01N2400/00 , G01N2800/7071 , G01N2800/7076
摘要： The present invention relates to a process for the non-destructive determination of gender, developmental stage and/or viability of an avian embryo in an egg, comprising (a) detecting at least a first developmental marker compound selected from sugars and/or amino acids, precursors and metabolites thereof in an egg at a time period of from the beginning of the incubation of the egg until the hatching; (b) measuring the amount of the at least first detected developmental marker compound, and (c) comparing the amount to a base line established for male and female, developmental stage of the embryo, and/or alive and deceased or non-developed embryo, to determine whether the embryo is viable, male and/or female, and/or the developmental stage of the embryo.

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式