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    • 1. 发明授权
    • Laser aligned robotic machining system for use in rebuilding heavy
machinery
    • 用于重型机械的激光对准机器人加工系统
    • US5768137A
    • 1998-06-16
    • US421008
    • 1995-04-12
    • Roger J. PolidoroHenry M. BassRussell J. ChurchillBruce L. ThomasLloyd K. Loftus
    • Roger J. PolidoroHenry M. BassRussell J. ChurchillBruce L. ThomasLloyd K. Loftus
    • G05B19/18G06F19/00G06G7/64G06G7/66
    • G05B19/182G05B2219/33002G05B2219/33027G05B2219/34065G05B2219/37275G05B2219/50168G05B2219/50173
    • A precision positioning system is used for resurfacing and repairing rails and guideways of large, heavy machinery at users facilities. The system has new components, an entire machining system, a new alignment system, parallel platforms for tool support and surface scanning. A sectioned, portable monorail frame is held by fixed supports at the locus of a heavy machine requiring guideway straightening. Fixed guides extend along the outer surface of the monorail. Guide wheels and drive wheels contact the guides and support and move an outer tubular beam carriage. An assembly of machining tools is adjustably positioned on the carriage. Laser alignment sources and sensors are connected to the carriage and to heavy machines off-axis and parallel to the monorail. Intelligent controls precisely position the tools for resurfacing the rails and guideways. Scanning and a printout of machine guideway accuracy, before and after the operation, provide written verification of quality improvement. The system increases accuracy and speed of machining, reduces chatter and vibration, eliminates imprecise manual determinations, and returns the equipment to acceptable improved tolerances. The system has applications in any machine tool rebuilder or company with a machine tool in need of requalification. Applications also include rail transport, autonomous vehicles, micro-machining, inspection camera positioning, laser machining, material deposition and other operations such as drilling, heat treating, brazing and welding.
    • 精密定位系统用于用户设施的大型重型机械的轨道和导轨的重铺和修理。 该系统具有新的组件,整个加工系统,新的对准系统,用于刀具支持和表面扫描的并行平台。 分段便携式单轨架由固定支架固定在需要导轨拉直的重型机器的轨迹上。 固定导轨沿着单轨的外表面延伸。 引导轮和驱动轮与引导件接触并支撑并移动外管式梁架。 加工工具的组件可调节地定位在托架上。 激光对准源和传感器连接到托架和离轴并且与单轨平行的重型机器。 智能控制器精确定位用于重新铺展导轨和导轨的工具。 扫描和打印机导轨精度,操作前后,提供书面验证质量改进。 该系统提高了加工的精度和速度,减少了颤动和振动,消除了不精确的手动测量,并将设备返回到可接受的改进公差。 该系统在任何机床重建工程师或具有需要重新鉴定的机床的公司都有应用。 应用还包括轨道交通,自主车辆,微机械加工,检测相机定位,激光加工,材料沉积等钻孔,热处理,钎焊和焊接等操作。
    • 2. 发明授权
    • Laser aligned five-axis position measurement device
    • 激光对准五轴位置测量装置
    • US5798828A
    • 1998-08-25
    • US614888
    • 1996-03-13
    • Bruce L. ThomasHenry M. BassLloyd K. LoftusRussell J. Churchill
    • Bruce L. ThomasHenry M. BassLloyd K. LoftusRussell J. Churchill
    • G01B11/26G01B11/30H04B10/00B23B39/08
    • G01B11/26G01B11/306Y10T408/175
    • A laser-based multi-axis position measurement unit measures position deviations in 5 axes while traversing a 6th linear axis. The apparatus includes three components: 1) a laser-beam unit which emits two parallel laser beams; 2) a sensor unit including at least three laser-position sensors, one of them being transparent; and 3) a microprocessor or computer unit which converts X,Y laser position data from the three sensors to displacements in 5 axes: X (horizontal), Y (vertical), Pitch (angular motion about the X axis), Yaw (angular motion about the Y axis), and Roll (angular motion about the line of travel). Readout of the 6th axis, the line of travel, is provided by means of a separate linear transducer or laser-based ranging system. The device includes an arrangement of three digital sensors on two parallel laser beams to deduce position in 5 axes. Applications for the measurement unit exist in machine tool measurement and calibration, robotics, coordinate measurement machines, optical alignment and other areas where position in multiple axes must be determined. The position information may be directly displayed or used as input for a closed-loop positioning system.
    • 基于激光的多轴位置测量单元测量5轴同时穿过第6个线性轴的位置偏差。 该装置包括三个部件:1)发射两个平行激光束的激光束单元; 2)传感器单元,其包括至少三个激光位置传感器,其中一个是透明的; 3)将X,Y激光位置数据从三个传感器转换为5轴的位移的微处理器或计算机单元:X(水平),Y(垂直),间距(X轴的角运动),Yaw 关于Y轴)和Roll(关于行程的角运动)。 通过单独的线性换能器或基于激光的测距系统提供第六轴的读数,行程。 该装置包括在两个平行的激光束上的三个数字传感器的布置,以推断在5个轴上的位置。 测量单元的应用存在于机床测量和校准,机器人,坐标测量机,光学对准以及其他必须确定多个轴位置的区域。 位置信息可以直接显示或用作闭环定位系统的输入。
    • 3. 发明授权
    • Optical chemical sensor and method using same employing a multiplicity
of fluorophores contained in the free volume of a polymeric optical
waveguide or in pores of a ceramic waveguide
    • 光学化学传感器和使用其的方法使用包含在聚合物光波导的自由体积中的多个荧光团或在陶瓷波导的孔中
    • US5577137A
    • 1996-11-19
    • US392152
    • 1995-02-22
    • Howard P. GrogerPeter LoRussell J. ChurchillMartin WeissShufang Luo
    • Howard P. GrogerPeter LoRussell J. ChurchillMartin WeissShufang Luo
    • G01N21/64G01N21/77G02B6/02G02B6/132G02B6/00G01N15/06
    • G02B6/132G01N21/6428G01N21/648G01N21/7703G02B6/02G01N2021/7793G01N21/6408
    • A fluorescent sensor for chemical analysis has a light source, an optical waveguide, and a detector. Fluorophores are associated with the optical waveguide. When an impervious waveguide is used, a fluorophore-containing layer is applied to a surface of the waveguide. The fluorophores are excited by a laser, a light emitting diode, an electroluminescent source or a lamp source emitting light propagating at angles to the waveguide. The light source is modulated. A mirror can be used to direct the light beam. The angle of light incidence on the waveguide can be altered by moving the waveguide itself. The waveguide traps the laser-induced fluorescence and projects fluorescence signals through a suitable filter to a photodetector or otherwise wavelength-specific photodetector positioned near the waveguide structure. Remote operation of the sensor is achieved using optical fibers. Patterned waveguides allow multiple excitation sources to illuminate multiple fluorescent probe materials. The change in fluorescence from each fluorophore is sensed as a vector response which is evaluated using digital signal processing. The sensor uses steady state fluorescence and fluorescence decay information to determine identity and concentration of analytes of interest. The invention is used for chemical analysis of gases or of liquid materials.
    • 用于化学分析的荧光传感器具有光源,光波导和检测器。 荧光团与光波导相关联。 当使用不透水波导时,将含荧光团的层施加到波导的表面。 荧光团由激光器,发光二极管,电致发光源或发射以波导角度传播的光的灯源激发。 光源被调制。 可以使用镜子来引导光束。 可以通过移动波导本身来改变波导上的光入射角度。 波导捕获激光诱导的荧光,并将荧光信号通过适当的滤光器投射到位于波导结构附近的光电检测器或其他波长特定的光电检测器。 使用光纤实现传感器的远程操作。 图案波导允许多个激发源照亮多个荧光探针材料。 感测来自每个荧光团的荧光的变化作为矢量响应,其使用数字信号处理进行评估。 传感器使用稳态荧光和荧光衰减信息来确定感兴趣的分析物的同一性和浓度。 本发明用于气体或液体材料的化学分析。
    • 4. 发明授权
    • Fluorescence decay measurement by calculation of inner product
    • 通过计算内部产物进行荧光衰减测量
    • US5757013A
    • 1998-05-26
    • US568382
    • 1995-12-06
    • Howard P. GrogerRussell J. ChurchillK. Peter LoShufang Luo
    • Howard P. GrogerRussell J. ChurchillK. Peter LoShufang Luo
    • G01N21/64F21V9/16
    • G01N21/6408
    • An apparatus and its accompanying method measures fluorescence decay, fluorescence amplitude and fluorescence polarization. The instrument includes a light emitting diode or laser diode light source, an amplified photodiode detector, and electronics and software for calculating the phase of the fluorescence from the computed inner product of the scattering and fluorescence signals. The electronics for measuring fluorescence decay includes two signal synthesizers, two downconverters, a simultaneously sampling analog-to-digital converter and means for calculating the inner product of the downconverted waveforms. A signal source, preferably a direct digital synthesizer, is used in combination with a digital-to-analog converter to provide a controllable output signal. That signal drives a modulatable light source, which is a light emitting diode, a laser diode or a combination of the two. Excitation light from the light source excites the sample fluorophore which is immobilized in a solid material. Fluorescence is detected using an amplified photodiode. The received signal is downconverted using a pair of mixers. The downconverted signals are digitized and stored. Preferably, the signals are digitized using a two-channel synchronous analog-to-digital converter controlled by a digital signal processor. Data from each channel are multiplied and summed to provide the inner product.
    • 一种仪器及其附带的方法测量荧光衰减,荧光振幅和荧光偏振。 该仪器包括发光二极管或激光二极管光源,放大光电二极管检测器,以及用于从计算的散射和荧光信号内积计算荧光相位的电子和软件。 用于测量荧光衰减的电子器件包括两个信号合成器,两个下变频器,同时采样模数转换器和用于计算下变换波形内积的装置。 信号源(优选直接数字合成器)与数模转换器组合使用以提供可控输出信号。 该信号驱动可调光源,其是发光二极管,激光二极管或两者的组合。 来自光源的激发光激发固定在固体材料中的样品荧光团。 使用放大的光电二极管检测荧光。 接收的信号使用一对混频器进行下变频。 下变频信号被数字化并存储。 优选地,使用由数字信号处理器控制的双通道同步模数转换器将信号数字化。 来自每个通道的数据相乘并相加以提供内部产品。
    • 6. 发明授权
    • Diode laser-based chemical and biological sensor
    • 二极管激光化学和生物传感器
    • US5766956A
    • 1998-06-16
    • US862929
    • 1997-05-27
    • Howard P. GrogerRussell J. ChurchillShu-Fang LuoK. Peter Lo
    • Howard P. GrogerRussell J. ChurchillShu-Fang LuoK. Peter Lo
    • G01N21/39G01N21/77G01N21/63
    • G01N21/7746G01N2021/391G01N2201/0612
    • A-compact, diode laser-based sensor has applications in biological and chemical analysis. Unlike existing optical waveguide-based sensors, no external coupling to external optical fibers or waveguides is required to perform optical chemical, immunological or nucleic acid-based assay or to detect the presence of toxic or otherwise important chemicals. The sensor includes a surface-sensitive diode laser having a substrate layer, an n-contact layer positioned on a bottom surface of the substrate, an n-clad layer overlying the top surface of the substrate, a first guide layer overlying the n-clad layer, a quantum well layer overlying the first guide layer, a second guide layer overlying the first quantum well layer, a p-clad layer overlying the second guided layer and a p-doped cap layer overlying the p-clad layer. A pair of electrodes separated by a surface-sensitive region is positioned on the cap layer. The surface active region includes an oxide layer grown on the thick cap layer and an absorbing or non-absorbing film deposited on the oxide layer. For internal reflection, inorganic material coatings are applied to end facets or Bragg reflectors are etched in the cap layer. Detectors are positioned proximate the diode laser for detecting changes in film thickness or refractive index, absorption or other optical properties resulting from film deposition, surface reactions such as immunological or ion-exchange reactions, or other detectable processes.
    • A型紧凑型二极管激光传感器在生物和化学分析中有应用。 与现有的基于光波导的传感器不同,不需要外部耦合到外部光纤或波导进行光学化学,免疫学或基于核酸的测定或检测有毒或其他重要化学物质的存在。 该传感器包括具有衬底层,位于衬底底表面上的n接触层,覆盖在衬底顶表面上的n覆盖层的表面敏感二极管激光器,覆盖n覆层的第一引导层 层,覆盖第一引导层的量子阱层,覆盖第一量子阱层的第二引导层,覆盖第二引导层的p覆盖层和覆盖p覆盖层的p掺杂覆盖层。 由表面敏感区域隔开的一对电极位于盖层上。 表面活性区域包括在厚盖层上生长的氧化物层和沉积在氧化物层上的吸收或非吸收膜。 对于内反射,将无机材料涂层施加到端面,或者在盖层中蚀刻布拉格反射器。 检测器位于二极管激光器附近,用于检测由膜沉积,表面反应如免疫或离子交换反应或其它可检测过程引起的膜厚度或折射率,吸收或其他光学性能的变化。
    • 7. 发明授权
    • Fluorescent probes based on the affinity of a polymer matrix for an analyte of interest
    • 基于聚合物基质对感兴趣分析物的亲和力的荧光探针
    • US06521185B1
    • 2003-02-18
    • US08553773
    • 1995-10-23
    • Howard P. GrogerShufang LuoK. Peter LoMartin WeissJames M. SloanRussell J. Churchill
    • Howard P. GrogerShufang LuoK. Peter LoMartin WeissJames M. SloanRussell J. Churchill
    • G01N2164
    • G01N21/6428G01N21/648G01N2021/6439G01N2021/6482
    • A highly-sensitive, rapid response fluorescent probe is based on the affinity of a polymer matrix for an analyte of interest. The probe includes a polymer matrix and a dye immobilized in the matrix. The polymer matrix has an affinity for an analyte of interest and the dye has little or no sensitivity to the analyte of interest when excited by an excitation source in a free state but has significant sensitivity to the analyte of interest when excited by the excitation source when immobilized in the matrix. Sensors incorporating the polymer/fluorophore probes of the present invention have the sensitivity and rapid response needed for detection of chemical agent and biological materials. Sensors using the probes provide sensitivity to Sarin at several hundred parts per trillion in one second or less. That is a notable advance over state-of-the-art detectors that require preconcentration steps, which in turn restrict response times to one minute or more. A wide-range of near-infrared excitable fluorophores are used as sensitive probes for analytes not detectable when the fluorophores are outside the polymer matrix. The present sensors provide early warning of the presence of toxic chemicals, provides for on-line analysis of trace materials in chemical and biological processing operations and biomedical processing operations, and provides for effective biomedical and environmental monitoring.
    • 高灵敏度,快速响应的荧光探针是基于聚合物基质对感兴趣的分析物的亲和力。 探针包括聚合物基质和固定在基质中的染料。 聚合物基质对感兴趣的分析物具有亲和力,并且当激发源在自由状态下激发时,染料对感兴趣的分析物几乎没有或没有敏感性,但当被激发源激发时对染料分析物具有显着的敏感性, 固定在基质中。 结合本发明的聚合物/荧光团探针的传感器具有检测化学试剂和生物材料所需的灵敏度和快速反应。 使用探针的传感器可以在一秒或更短的时间内以每万亿次几百份的比例提供对Sarin的敏感性。 这是一个显着的进步,超过最先进的检测器,需要预浓缩步骤,从而将响应时间限制在一分钟以上。 当荧光团在聚合物基质外部时,广泛的近红外可激发荧光团被用作不可检测的分析物的敏感探针。 本传感器提供有毒化学物质的早期预警,提供化学和生物加工操作和生物医学加工操作中痕量物质的在线分析,并提供有效的生物医学和环境监测。
    • 9. 发明授权
    • Chemical sensor using eddy current or resonant electromagnetic circuit
detection
    • 化学传感器采用涡流或谐振电磁回路检测
    • US5514337A
    • 1996-05-07
    • US179679
    • 1994-01-11
    • Howard P. GrogerRussell J. ChurchillJames Kelsch
    • Howard P. GrogerRussell J. ChurchillJames Kelsch
    • G01N27/02G01N27/06G01N27/12
    • G01N27/023
    • An instrument is applied to the measurement of chemical species and concentration through the use of a chemically-sensitive coating on the eddy current coil or in the vicinity of the eddy current coil which produces a change in impedance of the probe through induced eddy currents in the coating. An eddy current or resonance circuit chemical detector is a non-contact sensor for measuring chemical species identity and concentration. The chemical detector is resilient and does not require reference electrodes. The chemical sensor is selective as a result of data available on the change in vector impedance of the probe, the change in resonant frequency of the tuned circuit, and the availability of data to construct a vector response from multiple probes having differing chemistries. The probe is used in extreme temperatures.
    • 通过在涡流线圈或涡流线圈附近使用化学敏感性涂层,将仪器应用于化学物质和浓度的测量,通过涡流线圈中的感应涡流产生探头的阻抗变化 涂层。 涡流或谐振电路化学检测器是用于测量化学物种识别和浓度的非接触传感器。 化学检测器是弹性的,不需要参考电极。 化学传感器是选择性的,因为数据可用于探头的矢量阻抗的变化,调谐电路的谐振频率的变化,以及构建具有不同化学成分的多个探针的向量响应的数据的可用性。 探头在极端温度下使用。